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FER Gene

protein-coding   GIFtS: 65

GC05P108111
fer (fps/fes related) tyrosine kinase
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    
(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases
EC 2.7.10.2 3
TYK3 1, 2, 3, 5
c-FER 3
p94-FER 3
Descriptions
Tyrosine kinase 3 3
fer (fps/fes related) tyrosine kinase 2
phosphoprotein NCP94 2
External Ids
HGNC: 36551
Entrez Gene: 22412
UniProtKB: P165913
Ensembl: ENSG000001514227
Search outside databases for aliases for FER gene

Previous GC identifers: GC05P107703 GC05P108524 GC05P108114 GC05P108159

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for FER:
Fer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. It
regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via
growth factor receptors. [provided by RefSeq]

UniProtKB/Swiss-Prot: FER_HUMAN, P16591
Function: Tyrosine kinase of the non-receptor type. Probably performs an important function,
perhaps in regulatory processes such as cell cycle control

Gene Wiki entry for FER

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the FER gene  

Entrez Gene cytogenetic band: 5q21   Ensembl cytogenetic band:  5q21.3   HGNC cytogenetic band: 5q21

FER Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P108111:     (about GC identifiers)

Start:
108,111,422 bp from pter
End:
108,551,272 bp from pter
Size:
439,851 bases
Orientation:
plus strand
RefSeq DNA sequence:
NC_000005.8  NT_034772.5  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: FER_HUMAN, P16591 (See protein sequence)
Recommended Name: Proto-oncogene tyrosine-protein kinase FER  
Size: 822 amino acids; 94638 Da
Subcellular location: Cytoplasm. Nucleus. Note=Associated with the chromatin

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_005237.2  

    ENSEMBL proteins: 
    ENSP00000281092 


    Human Recombinant Proteins 
    Invitrogen human recombinant proteins for FER
    Millipore Purified and/or Recombinant FER Protein
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (FER)
    Browse Abnova for Human Recombinant Proteins
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    2 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634 nucleus IEA--
    GO:0005737 cytoplasm IEA--
    About this table

    Antibodies for FER: 
    Browse Antibodies Central at Invitrogen
    Millipore Mono- and Polyclonal Antibodies for the study of FER
    Sigma-Aldrich Antibodies for FER
    Browse R&D Systems for Antibodies
    Cell Signaling Technology (CST) Antibodies for FER 
    Antibodies from Abcam (FER), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (FER)
    Novus Biologicals Antibodies for FER

    Assays for FER: 
    Invitrogen Assays for FER
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    5/7 InterPro domains/families (see all 7 ):
     IPR017441 Protein_kinase_ATP_BS
     IPR001060 FCH
     IPR001245 Tyr_pkinase
     IPR016250 TyrPK_fps
     IPR000980 SH2


       GeneDecks  FER for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry P16591

    ProtoNet protein and cluster: P16591

    3 Blocks protein families:
    IPB000980 SH2 domain signature
    IPB001060 Cdc15/Fes/CIP4
    IPB008266 Tyrosine protein kinase


    UniProtKB/Swiss-Prot: FER_HUMAN, P16591
    Similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily
    Similarity: Contains 1 FCH domain
    Similarity: Contains 1 protein kinase domain
    Similarity: Contains 1 SH2 domain

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (FER)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (FER)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_005246

                  Applied Biosystems Silencer® siRNAs for FER

                  Sigma-Aldrich siRNA and siRNA Panels for FER  
                         Sigma-Aldrich shRNA Panels and shRNA for FER  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Browse Clone Ranger at Invitrogen for clones
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_005246
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_005246
                                     untagged cDNA clones in CMV expression vector (see all 2): NM_005246 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_005246

    UniProtKB/Swiss-Prot: FER_HUMAN, P16591
    Function: Tyrosine kinase of the non-receptor type. Probably performs an important function,
    perhaps in regulatory processes such as cell cycle control
    Catalytic activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
    Enzyme Number (IUBMB): EC 2.7.10.2 

    Genatlas biochemistry entry for FER:
    fer (fps/fes related) oncogene homolog

    1 MGI mutant phenotype (inferred from 2 alleles(MGI details for Fert2):

    normal

    5 Gene Ontology (GO) molecular function terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166 nucleotide binding IEA--
    GO:0004715 non-membrane spanning protein tyrosine kinase activity IEA--
    GO:0005515 protein binding IEA--
    GO:0005524 ATP binding IEA--
    GO:0016740 transferase activity IEA--
    About this table

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    2 Invitrogen iPath™ Online BioAtlas - Pathways for FER (Maps provided by GeneGo):
     Cadherin-mediated cell adhesion
     Fc epsilon RI pathway

       GeneDecks  FER for the pathways selected above  
    About GeneDecksing

    3 Millipore Pathways for FER
     Neurophysiological process Receptor-mediated axon growth repulsion
     Cell adhesion Cadherin-mediated cell adhesion
     Immune response Fc epsilon RI pathway

       GeneDecks  FER for the pathways selected above  
    About GeneDecksing

    2 Sigma-Aldrich "Your Favorite Gene" Pathways for  FER  (Your Favorite Gene powered by Ingenuity) 
     Leukocyte Extravasation Signaling
     Germ Cell-Sertoli Cell Junction Signaling

       GeneDecks  FER for the pathways selected above  
    About GeneDecksing

    3 Cell Signaling Technology (CST) Pathways for FER: 
     Wnt/b-Catenin Signaling
     Translational Control: Regulation of eIF4E and p70 S6 Kinase
     Protein Acetylation

       GeneDecks  FER for the pathways selected above  
    About GeneDecksing

    1 Kegg Pathway  (Kegg details for FER):
     hsa04520 Adherens junction

       GeneDecks  FER for the pathways selected above  
    About GeneDecksing
     Gene Network CentralTM Interacting Genes and Proteins Network for  FER 


    5 Interacting proteins for FER (P165912) via UniProtKB, MINT, and/or STRING
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ERBB2P046262MINT-74533
    ERBB3P218602MINT-74534
    --O424862MINT-6764543 MINT-6792840
    --O130162MINT-6764561
    --Q022482MINT-45999
    About this table

    2 Gene Ontology (GO) biological process terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007242 intracellular signaling cascade TAS2209086
    GO:0018108 peptidyl-tyrosine phosphorylation IEA--
    About this table
    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for FER
    3 Novoseek chemical compound relationships for FER gene
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    tyrosine 67.29 97 11006284 (6), 12738762 (5), 12972546 (5), 19159681 (5) (see all 28)
    iron 30.95 9 8144027 (1), 8861664 (1), 11427634 (1), 16060121 (1) (see all 6)
    phosphatidylinositol 23.96 7 11006284 (3), 12738762 (1)
    About this table


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (FER)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (FER)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_005246

                  Sigma-Aldrich siRNA and siRNA Panels for FER  
                         Sigma-Aldrich shRNA Panels and shRNA for FER  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_005246  

    REFSEQ mRNAs for FER gene: 

    NM_005246.2   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_005246  

                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_005246
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_005246
                                     untagged cDNA clones in CMV expression vector (see all 2): NM_005246 

    Additional cDNA sequence: 

    AK293376.1 AK296874.1 AK299855.1 AK315234.1 BC017060.1 BC058030.1 CR612158.1 J03358.1 

    9 DOTS entries:

    DT.204962  DT.91664750  DT.100015683  DT.101956348  DT.100664607  DT.100743018  DT.95147128  DT.97773964 
    DT.95197173 

    24/28 AceView cDNA sequences (see all 28 ):

    AL553206 BM461740 BE464122 BM836424 J03358 CR612158 NM_005246 BX111092 
    BX329084 BC017060 BQ948178 BG611933 AI969987 CB120902 BG199979 BX645595 
    BX327980 BE620300 BU155168 AA534773 AI654758 CB853071 BC058030 CF129502 

    highest scoring ESTs for FER:

    J03358 AA534773 AI654758 AI918808 AI969987 BE464122 BE548973 BG199979 BQ948178 CF129502 

    Unigene Cluster for FER:

    Fer (fps/fes related) tyrosine kinase
    Hs.221472  [show with all ESTs]
    Unigene Representative Sequence: AK299855


    GeneLoc Exon Structure

    1 Ensembl transcript including schematic representation:
    ENST00000281092  
    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    FER expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for FER

    1 / 2 / 3

    4 probe-sets matching FER gene


    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank

    35133_at2, 3 U95-A 2 1.00 0.97 1.00 1.00 J03358 1.00 0.87 0.94 1

    1623_s_at2, 3 U95-A 2 1.00 0.94 0.46 0.36 HG1761-HT1778 0.20 1.00 0.72 1

    206412_at2, 3 U133-A 2 1.00 0.95 -- -- NM_005246 0.60 1.00 0.82 1

    206412_at2 U133Plus2 2 1.00 0.95 -- -- -- -- -- -- --
    About this table
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: GTGCAATTCC

    SOURCE GeneReport for Unigene cluster: Hs.221472

    Expression variation in blood from EXPOLDB for FER

    UniProtKB/Swiss-Prot: FER_HUMAN, P16591
    Tissue specificity: Expressed in a variety of lymphoid cell lines

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section


    Orthologs for FER gene from 5/9 species (see all 9 )
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    FER1   -- fer (fps/fes related) tyrosine kinase 93.27(n)
    95.62(a)
    403754  NM_001003141.1  NP_001003141.1 
    chimpanzee
    (Pan troglodytes)
    FER1   -- fer (fps/fes related) tyrosine kinase 99.59(n)
    99.88(a)
    461981  XM_001139935.1  XP_001139935.1 
    rat
    (Rattus norvegicus)
    Fert21   -- fer (fms/fps related) protein kinase, testis specific more 86.74(n)
    93.31(a)
    301737  XM_217492.4  XP_217492.3 
    mouse
    (Mus musculus)
    Fert21, 5 175
    fer (fms/fps related) protein kinase, testis specific more1, 5 88.36(n)1
    92.94(a)1
    141581  NM_001037997.11  NP_001033086.11 
     AF2865375  AK0211755  (see all 13)
    chicken
    (Gallus gallus)
    FER1   -- fer (fps/fes related) tyrosine kinase (phosphoprotein more 81.31(n)
    87.96(a)
    415614  XM_413981.2  XP_413981.2 
    About this table        Species with no ortholog for FER

    ENSEMBL Gene Tree for FER
    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for FER gene
    FES2  

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/1995 NCBI SNPs in FER are shown (see all 1995 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 500)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 5 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ------------
    rs11333921,2
    C,F,H108551192(+) CGCCAA/TACTCA 1 -- ut3111Minor allele frequency- T:0.07NA EU EA WA 970
    rs339408431,2
    C,F108261446(-) TACCAT/CAGATG 1 V/M mis15Minor allele frequency- C:0.03NA EU EA WA 496
    rs344999461,2
    C,F108309808(+) CTGCAC/GTGGGC 1 L/V mis14Minor allele frequency- G:0.05EU EA WA 420
    rs342043081,2
    C,F108318519(+) TATCAT/CACAAT 1 T/I mis14Minor allele frequency- C:0.12EU EA WA 420
    rs351502101,2
    C,F108199308(+) GACAGG/TTTACC 1 V/F mis14Minor allele frequency- T:0.01EU EA WA 420
    rs131814291,2
    H108110423(+) AAAACT/ACCGAA 1 -- ng514Minor allele frequency- A:0.00EU EA WA 418
    rs342598241,2
    C108309820(+) CTTCAG/CCAGTA 1 P/A mis14Minor allele frequency- C:0.00EU EA WA 420
    rs342699851,2
    C108322868(+) TCCTCA/TACTTA 1 Q/L mis14Minor allele frequency- T:0.00EU EA WA 420
    rs22290851,2
    C,F,H108161866(+) ACAGTA/GAAGAA 1 V/V syn113Minor allele frequency- G:0.15MN NA EU EA WA 1090
    rs9197711,2
    C,F,H108408318(-) GTTTTA/GTCCTT 1 D/D syn14Minor allele frequency- G:0.05EU EA WA 420
    About this table

    HapMap Linkage Disequilibrium images for FER (up to first 250kb)

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    OMIM: 176942

    5 Novoseek disease relationships for FER gene

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    prostate carcinoma 23.29 2 10687853 (2)
    metaplasia 21.50 1 10687853 (1)
    prostate cancer 5.94 11 19147545 (7), 10687853 (1)
    cancer 0.00 2 16732323 (1), 10687853 (1)
    tumors 0.00 1 19147545 (1)
    About this table

    Human Gene Mutation Database: FER
    Tumor Gene Database: FER

    (Possibly Related Articles in Doctor's Guide)
    About This Section

      --

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    10/71 PubMed articles for FER gene (see all 71 ):
    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)
    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section

    Entrez Gene: 2241 HGNC: 3655 AceView: FER Ensembl:ENSG00000151422 euGenes: HUgn2241
    ECgene: FER H-InvDB: FER
    (According to HUGE)
    About This Section

      --
    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section

    NameDescription
    ATLAS Chromosomes in Cancer entry for FER Genetics and Cytogenetics in Oncology and Haematology
    (Available from WIS Yeda, Salk, Tufts)
    About This Section

      --
    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for FER:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
      Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for FER-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for FER Antibodies for FER
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for FER Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
     Antibodies   Primer Pairs  
     Cell Culture Products   ELISAs  
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     Cell Selection/Detection Kits & Reagents   ELISA/Assay Development Kits & Reagents  
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     Recombinant & Natural Proteins  

     Search for Recombinant Proteins
     Antibodies (FER)
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     Custom Service for Mouse Mab
     Custom Service for Rabbit Pab from Full-length Protein
      
     Antibodies & Assays for FER 

     Recombinant Proteins
    (FER)
     Antibodies (FER)
     Search OriGene for FER
     Search Tocris compounds for FER




     Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
     Antibodies for FER

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