Aliases for FEM1A Gene
Aliases for FEM1A Gene
External Ids for FEM1A Gene
- HGNC: 16934
- Entrez Gene: 55527
- Ensembl: ENSG00000141965
- OMIM: 613538
- UniProtKB: Q9BSK4
Previous GeneCards Identifiers for FEM1A Gene
- GC19P004883
- GC19P004732
- GC19P004742
- GC19P004553
Summaries for FEM1A Gene
GeneCards Summary for FEM1A Gene
FEM1A (Fem-1 Homolog A) is a Protein Coding gene. Diseases associated with FEM1A include Rhabdomyosarcoma. GO annotations related to this gene include ubiquitin-protein transferase activity and EP4 subtype prostaglandin E2 receptor binding. An important paralog of this gene is FEM1C.
UniProtKB/Swiss-Prot for FEM1A Gene
-
Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit (By similarity). May participate in antiinflammatory signaling via its interaction with PTGER4.
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FEM1A Gene
Genomics for FEM1A Gene
Regulatory Elements for FEM1A Gene
Enhancers for FEM1A Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH19G004828 | 1.3 | ENCODE dbSUPER | 11.6 | +39.5 | 39486 | 4.6 | HDGF ARNT SIN3A ARID4B DMAP1 YY1 SLC30A9 ZNF143 ZNF207 ZNF548 | SAFB2 PLIN3 SAFB ARRDC5 FEM1A MIR7-3 MIR7-3HG SNRPEP4 ENSG00000269807 DPP9-AS1 |
| GH19G004744 | 1.1 | Ensembl ENCODE | 13.4 | -46.6 | -46584 | 1.1 | FOXA2 SIN3A INSM2 KLF17 EGR1 ZNF366 ZMIZ1 FOS CREM EGR2 | MIR7-3HG MIR7-3 FEM1A DPP9 PLIN3 GC19M004737 TRV-CAC3-1 |
| GH19G004741 | 0.7 | ENCODE | 13.4 | -49.0 | -48967 | 1.4 | MXI1 ZNF473 ZSCAN4 CEBPG ZIC2 ZNF48 RAD21 ZFHX2 ZBTB48 SMC3 | MIR7-3 MIR7-3HG FEM1A PLIN3 TRV-CAC3-1 GC19M004737 |
| GH19G004790 | 1.4 | ENCODE dbSUPER | 0.7 | +0.2 | 208 | 2.4 | CREB3L1 DMAP1 FEZF1 YY1 SLC30A9 ZNF143 SP3 NFYC TBX21 MEF2D | DPP9-AS1 SAFB2 ENSG00000267030 SAFB ENSG00000267255 ENSG00000267769 SH3GL1 HDGFL2 ENSG00000268536 SNRPEP4 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FEM1A on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for FEM1A Gene
- Chromosome:
- 19
- Start:
- 4,791,681 bp from pter
- End:
- 4,801,273 bp from pter
- Size:
- 9,593 bases
- Orientation:
- Plus strand
Genomic View for FEM1A Gene
Genes around FEM1A on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19p13.3 by Ensembl
- 19p13.3 by Entrez Gene
- 19p13.3 by HGNC
FEM1A Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FEM1A Gene
Proteins for FEM1A Gene
-
Protein details for FEM1A Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9BSK4-FEM1A_HUMAN
- Recommended name:
- Protein fem-1 homolog A
- Protein Accession:
- Q9BSK4
- B2RDI3
- Q711P8
- Q9NPN7
- Q9NPW8
Protein attributes for FEM1A Gene
- Size:
- 669 amino acids
- Molecular mass:
- 73639 Da
- Quaternary structure:
-
- Component of some E3 ubiquitin-protein ligase complex (By similarity). Interacts with PTGER4.
Protein Expression for FEM1A Gene
Post-translational modifications for FEM1A Gene
Other Protein References for FEM1A Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for FEM1A
- Invitrogen Antibodies for FEM1A
- antibodies-online Antibodies for FEM1A: See all 31
- GeneTex FEM1A antibody for FEM1A
Protein Products
-
OriGene Purified Proteins for FEM1A
- Search Origene for MassSpec and Protein Over-expression Lysates for FEM1A
- Origene Custom Protein Services for FEM1A
- antibodies-online Proteins for FEM1A: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Proteins for FEM1A
Assay Products
- antibodies-online Kits for FEM1A: See all 3
No data available for DME Specific Peptides for FEM1A Gene
Domains & Families for FEM1A Gene
Gene Families for FEM1A Gene
Protein Domains for FEM1A Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for FEM1A Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9BSK4- Family:
-
- Belongs to the fem-1 family.
Function for FEM1A Gene
Molecular function for FEM1A Gene
- UniProtKB/Swiss-Prot Function:
- Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit (By similarity). May participate in antiinflammatory signaling via its interaction with PTGER4.
- UniProtKB/Swiss-Prot Induction:
- Frequently down-regulated in rhabdomyosarcoma.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004842 | ubiquitin-protein transferase activity | ISS | -- |
| GO:0031867 | EP4 subtype prostaglandin E2 receptor binding | IPI | 16424369 |
Phenotypes for FEM1A Gene
- GenomeRNAi human phenotypes for FEM1A:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for FEM1A gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FEM1A gene
- Search ViGene Biosciences for FEM1A
CRISPR Products
-
OriGene CRISPR knockouts for FEM1A
-
Santa Cruz Biotechnology (SCBT) CRISPR for FEM1A
- GenScript: Design CRISPR guide RNA sequences for FEM1A
miRNA for FEM1A Gene
- miRTarBase miRNAs that target FEM1A
-
- hsa-mir-760 (MIRT036724)
- hsa-mir-504-5p (MIRT041076)
- hsa-mir-484 (MIRT042261)
- hsa-mir-423-3p (MIRT042591)
- hsa-mir-431-5p (MIRT293799)
- hsa-mir-649 (MIRT293801)
- hsa-mir-548t-3p (MIRT293803)
- hsa-mir-548aa (MIRT293804)
- hsa-mir-4421 (MIRT293805)
- hsa-mir-4424 (MIRT293806)
- hsa-mir-4682 (MIRT293807)
- hsa-mir-548ap-3p (MIRT293808)
- hsa-mir-548as-3p (MIRT293809)
- hsa-mir-548at-3p (MIRT293810)
- hsa-mir-5692a (MIRT293811)
- hsa-mir-5699-3p (MIRT293812)
- hsa-mir-548ay-3p (MIRT293813)
- hsa-mir-6796-5p (MIRT460555)
- hsa-mir-2110 (MIRT460556)
- hsa-mir-6742-5p (MIRT460557)
- hsa-mir-4472 (MIRT460558)
- hsa-mir-4447 (MIRT460559)
- hsa-mir-3151-5p (MIRT460560)
- hsa-mir-491-5p (MIRT460561)
- hsa-mir-6780b-5p (MIRT460562)
- hsa-mir-4725-3p (MIRT460563)
- hsa-mir-4271 (MIRT460564)
- hsa-mir-4764-5p (MIRT460565)
- hsa-mir-493-3p (MIRT460566)
- hsa-mir-581 (MIRT460567)
- hsa-mir-4673 (MIRT460568)
- hsa-mir-4645-5p (MIRT460569)
- hsa-mir-4514 (MIRT460570)
- hsa-mir-4692 (MIRT460571)
- hsa-mir-1324 (MIRT460572)
- hsa-mir-299-3p (MIRT460573)
- hsa-mir-1265 (MIRT460574)
- hsa-mir-4524b-3p (MIRT460575)
- hsa-mir-1273d (MIRT460576)
- hsa-mir-6757-5p (MIRT460577)
- hsa-mir-632 (MIRT460578)
- hsa-mir-4288 (MIRT460579)
- hsa-mir-6780a-5p (MIRT460580)
- hsa-mir-6779-5p (MIRT460581)
- hsa-mir-3689c (MIRT460582)
- hsa-mir-3689b-3p (MIRT460583)
- hsa-mir-3689a-3p (MIRT460584)
- hsa-mir-30b-3p (MIRT460585)
- hsa-mir-1273h-5p (MIRT460586)
- hsa-mir-4279 (MIRT460587)
- hsa-mir-4451 (MIRT460588)
- hsa-mir-6799-5p (MIRT460589)
- hsa-mir-6883-5p (MIRT460590)
- hsa-mir-6785-5p (MIRT460591)
- hsa-mir-149-3p (MIRT460592)
- hsa-mir-650 (MIRT460593)
- hsa-mir-3612 (MIRT460594)
- hsa-mir-657 (MIRT460595)
- hsa-mir-509-3p (MIRT460596)
- hsa-mir-1827 (MIRT460597)
- hsa-mir-17-3p (MIRT460598)
- hsa-mir-1184 (MIRT460599)
- hsa-mir-3158-5p (MIRT460600)
- hsa-mir-1976 (MIRT460601)
- hsa-mir-3653-5p (MIRT460602)
- hsa-mir-5088-3p (MIRT460603)
- hsa-mir-6871-5p (MIRT460604)
- hsa-mir-6831-5p (MIRT460605)
- hsa-mir-6873-5p (MIRT460606)
- hsa-mir-3927-3p (MIRT460607)
- hsa-mir-4291 (MIRT460608)
- hsa-mir-4710 (MIRT460609)
- hsa-mir-3175 (MIRT460610)
- hsa-mir-4728-5p (MIRT460611)
- hsa-mir-8085 (MIRT460612)
- hsa-mir-4722-5p (MIRT460613)
- hsa-mir-6731-5p (MIRT460614)
- hsa-mir-7854-3p (MIRT460615)
- hsa-mir-6804-5p (MIRT460616)
- hsa-mir-6787-3p (MIRT460617)
- hsa-mir-4768-3p (MIRT460618)
- hsa-mir-922 (MIRT460619)
- hsa-mir-6165 (MIRT460620)
- hsa-mir-5581-3p (MIRT490635)
- hsa-mir-6848-5p (MIRT490637)
- hsa-mir-6846-5p (MIRT490638)
- hsa-mir-4697-5p (MIRT490639)
- hsa-mir-4488 (MIRT490640)
- hsa-mir-1237-5p (MIRT490641)
- hsa-mir-6816-5p (MIRT490642)
- hsa-mir-3196 (MIRT490643)
- hsa-mir-3180-3p (MIRT490644)
- hsa-mir-3180 (MIRT490645)
- hsa-mir-4467 (MIRT490646)
- hsa-mir-8072 (MIRT490647)
- hsa-mir-4532 (MIRT490648)
- hsa-mir-3960 (MIRT490649)
- hsa-mir-384 (MIRT551918)
- hsa-mir-3685 (MIRT551919)
- hsa-mir-8077 (MIRT551920)
- hsa-mir-643 (MIRT551921)
- hsa-mir-4638-5p (MIRT551922)
- hsa-mir-5708 (MIRT571370)
- hsa-mir-6720-5p (MIRT571371)
- hsa-mir-6512-3p (MIRT571372)
- hsa-mir-6849-3p (MIRT571373)
- hsa-mir-4293 (MIRT571374)
- hsa-mir-4439 (MIRT606832)
- hsa-mir-3136-5p (MIRT606833)
- hsa-mir-3118 (MIRT606834)
- hsa-mir-134-5p (MIRT606835)
- hsa-mir-6857-3p (MIRT606836)
- hsa-mir-6855-3p (MIRT606837)
- hsa-mir-4513 (MIRT606838)
- hsa-mir-6730-3p (MIRT606839)
- hsa-mir-5190 (MIRT606840)
- hsa-mir-6865-3p (MIRT606841)
- hsa-mir-520h (MIRT606842)
- hsa-mir-520g-3p (MIRT606843)
- hsa-mir-3973 (MIRT606844)
- hsa-mir-4519 (MIRT606845)
- hsa-mir-888-3p (MIRT606846)
- hsa-mir-93-5p (MIRT611836)
- hsa-mir-526b-3p (MIRT611837)
- hsa-mir-519d-3p (MIRT611838)
- hsa-mir-20b-5p (MIRT611839)
- hsa-mir-20a-5p (MIRT611840)
- hsa-mir-17-5p (MIRT611841)
- hsa-mir-106b-5p (MIRT611842)
- hsa-mir-106a-5p (MIRT611843)
- hsa-mir-520e (MIRT616799)
- hsa-mir-520d-3p (MIRT616800)
- hsa-mir-520c-3p (MIRT616801)
- hsa-mir-520b (MIRT616802)
- hsa-mir-520a-3p (MIRT616803)
- hsa-mir-373-3p (MIRT616804)
- hsa-mir-372-3p (MIRT616805)
- hsa-mir-302e (MIRT616806)
- hsa-mir-302d-3p (MIRT616807)
- hsa-mir-302c-3p (MIRT616808)
- hsa-mir-302b-3p (MIRT616809)
- hsa-mir-302a-3p (MIRT616810)
- hsa-mir-1200 (MIRT649232)
- hsa-mir-6829-3p (MIRT649233)
- hsa-mir-6791-3p (MIRT649234)
- hsa-mir-2276-3p (MIRT649235)
- hsa-mir-544b (MIRT649236)
- hsa-mir-660-3p (MIRT649237)
- hsa-mir-4324 (MIRT649238)
- hsa-mir-365b-5p (MIRT703568)
- hsa-mir-365a-5p (MIRT703569)
- hsa-mir-8052 (MIRT703570)
- hsa-mir-3199 (MIRT703571)
- hsa-mir-6778-3p (MIRT703572)
- hsa-mir-6747-3p (MIRT703573)
- hsa-mir-6727-3p (MIRT703574)
- hsa-mir-4722-3p (MIRT703575)
- hsa-mir-4740-3p (MIRT703576)
- hsa-mir-452-3p (MIRT719368)
- hsa-mir-6769a-5p (MIRT719369)
- hsa-mir-6769b-5p (MIRT719370)
- hsa-mir-92a-2-5p (MIRT719371)
- hsa-mir-654-5p (MIRT719372)
- hsa-mir-541-3p (MIRT719373)
- hsa-mir-4456 (MIRT719374)
- hsa-mir-3922-3p (MIRT719375)
- hsa-mir-3176 (MIRT719376)
- hsa-mir-6791-5p (MIRT719377)
- hsa-mir-3190-5p (MIRT719378)
- hsa-mir-4292 (MIRT719379)
- hsa-mir-4308 (MIRT719380)
- hsa-mir-3126-3p (MIRT719381)
- hsa-mir-651-5p (MIRT719382)
- hsa-mir-6500-5p (MIRT719383)
- hsa-mir-4633-3p (MIRT719384)
miRNA Products
- Search ViGene Biosciences for FEM1A
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FEM1A
- Browse OriGene Inhibitory RNA Products For FEM1A
-
ViGene Biosciences ready-to-package AAV shRNAs for FEM1A gene
Clone Products
-
OriGene ORF clones in human for FEM1A
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for FEM1A
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
Horizon Cell Lines for FEM1A
-
ViGene Biosciences adenoviral particle packaged cDNA for FEM1A gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FEM1A gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FEM1A gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FEM1A Gene
Localization for FEM1A Gene
Subcellular locations from UniProtKB/Swiss-Prot for FEM1A Gene
- Cytoplasm.
| Compartment | Confidence |
|---|---|
| cytosol | 2 |
| mitochondrion | 1 |
| nucleus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
Pathways & Interactions for FEM1A Gene
No Data Available
UniProtKB/Swiss-Prot Q9BSK4-FEM1A_HUMAN
- Pathway: Protein modification; protein ubiquitination.
Interacting Proteins for FEM1A Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016567 | protein ubiquitination | IEA | -- |
| GO:0043687 | post-translational protein modification | TAS | -- |
| GO:0050728 | negative regulation of inflammatory response | IDA | 16424369 |
| GO:0051438 | regulation of ubiquitin-protein transferase activity | ISS | -- |
No data available for Pathways by source and SIGNOR curated interactions for FEM1A Gene
Transcripts for FEM1A Gene
mRNA/cDNA for FEM1A Gene
- (1) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (231) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FEM1A Gene
CRISPR Products
-
OriGene CRISPR knockouts for FEM1A
-
Santa Cruz Biotechnology (SCBT) CRISPR for FEM1A
- GenScript: Design CRISPR guide RNA sequences for FEM1A
miRNA Products
- Search ViGene Biosciences for FEM1A
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FEM1A
- Browse OriGene Inhibitory RNA Products For FEM1A
-
ViGene Biosciences ready-to-package AAV shRNAs for FEM1A gene
Clone Products
-
OriGene ORF clones in human for FEM1A
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for FEM1A
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Expression for FEM1A Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Peripheral Nervous System (Nervous System)
- Schwann Precursor Cells Peripheral Nerve Domain
-
Skeletal Muscle (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for FEM1A Gene
This gene is overexpressed in Muscle - Skeletal (x20.8).
This gene is overexpressed in Adrenal (40.1) and Plasma (24.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for FEM1A Gene
NURSA nuclear receptor signaling pathways regulating expression of FEM1A Gene:
FEM1ASOURCE GeneReport for Unigene cluster for FEM1A Gene:
Hs.515082mRNA Expression by UniProt/SwissProt for FEM1A Gene:
Q9BSK4-FEM1A_HUMAN
Tissue specificity:
Present in macrophages derived from peripheral blood monocytes. Also present in atheromata (at protein level).
Evidence on tissue expression from TISSUES for FEM1A Gene
- Muscle(4.7)
- Kidney(4.2)
- Nervous system(4.2)
- Skin(2.1)
Primer Products
-
OriGene qPCR primer pairs for FEM1A
-
OriGene qPCR primer pairs and template standards for FEM1A
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for FEM1A Gene
Orthologs for FEM1A Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FEM1A 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | FEM1A 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | FEM1A 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | FEM1A 35 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | 4931440F15Rik 35 |
|
OneToMany | |
| Fem1a 34 16 35 |
|
||||
| platypus (Ornithorhynchus anatinus) |
Mammalia | FEM1A 35 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Fem1a 34 |
|
||
| chicken (Gallus gallus) |
Aves | FEM1A 34 35 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | fem1a 34 35 |
|
||
| wufi20c04 34 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | CG6966 36 35 |
|
||
| CG11896 36 |
|
|
|||
| worm (Caenorhabditis elegans) |
Secernentea | fem-1 36 35 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToMany |
- Species where no ortholog for FEM1A was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Paralogs for FEM1A Gene
(2) SIMAP similar genes for FEM1A Gene using alignment to 1 proteins:
Pseudogenes.org Pseudogenes for FEM1A Gene
Variants for FEM1A Gene
| SNP ID | Clin | Chr 19 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000625232 | -- | 4,795,663(+) | GCCAC(C/T)TCCCC | downstream-variant-500B | |
| rs1000976145 | -- | 4,795,986(+) | CCACT(A/G)CACCT | downstream-variant-500B | |
| rs1002244460 | -- | 4,791,146(+) | AAATG(A/C)ATAAA | upstream-variant-2KB | |
| rs1002642024 | -- | 4,789,717(+) | TCTGT(C/T)GCCCA | upstream-variant-2KB | |
| rs1002701738 | -- | 4,790,906(+) | AGTCC(C/T)AGCTA | upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1062709 | CNV | loss | 25217958 |
| nsv962994 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
17.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.04;
21.32% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FEM1A Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FEM1A Gene
Disorders for FEM1A Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| rhabdomyosarcoma |
|
|
Search FEM1A in MalaCards
View complete list of genes associated with diseases
Relevant External Links for FEM1A
No data available for UniProtKB/Swiss-Prot and Genatlas for FEM1A Gene
Publications for FEM1A Gene
- A novel prostaglandin E receptor 4-associated protein participates in antiinflammatory signaling. (PMID: 16424369) Takayama K. … Libby P. (Circ. Res. 2006) 3 4 22 64
- FEM1A is a candidate gene for polycystic ovary syndrome. (PMID: 16390781) Maher J.F. … Cowan B.D. (Gynecol. Endocrinol. 2005) 3 4 46 64
- The Fem1a gene is downregulated in Rhabdomyosarcoma. (PMID: 16254458) Ventura-Holman T. … Maher J.F. (Tumor Biol. 2005) 3 4 22 64
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 46 64
- Family-based analysis of candidate genes for polycystic ovary syndrome. (PMID: 20200332) Ewens K.G. … Spielman R.S. (J. Clin. Endocrinol. Metab. 2010) 3 46 64
Products for FEM1A Gene
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