Aliases for FDXR Gene
External Ids for FDXR Gene
Previous Symbols for FDXR Gene
This gene encodes a mitochondrial flavoprotein that initiates electron transport for cytochromes P450 receiving electrons from NADPH. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012]
GeneCards Summary for FDXR Gene
FDXR (Ferredoxin Reductase) is a Protein Coding gene. Diseases associated with FDXR include locked-in syndrome and prostate cancer. Among its related pathways are Pathways in cancer and Akt Signaling. GO annotations related to this gene include NADPH binding and NADPH-adrenodoxin reductase activity.
UniProtKB/Swiss-Prot for FDXR Gene
Serves as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver