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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FDX1L Gene

protein-coding   GIFtS: 45
GCID: GC19M010416

Ferredoxin 1-Like

  Search for FDX1L
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ferredoxin 1-Like1 2
Ferredoxin-1-Like Protein2 3
FDX22
Adrenodoxin-Like Protein, Mitochondrial2

External Ids:    HGNC: 305461   Entrez Gene: 1128122   Ensembl: ENSG000002676737   OMIM: 6145855   UniProtKB: Q6P4F23   

Export aliases for FDX1L gene to outside databases

Previous GC identifers: GC19M010278 GC19M010281 GC19M010001


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for FDX1L Gene: 
FDX1L (ferredoxin 1-like) is a protein-coding gene. Among its related super-pathways are Electron Transport from NADPH to Ferredoxin and Metabolic pathways. GO annotations related to this gene include electron carrier activity and 2 iron, 2 sulfur cluster binding. An important paralog of this gene is FDX1.

UniProtKB/Swiss-Prot: ADXL_HUMAN, Q6P4F2
Function: Essential for heme A and Fe/S protein biosynthesis




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NT_011295.11  NC_018930.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FDX1L gene promoter:
         PPAR-gamma1   Sp1   AP-2beta   AP-2gamma   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFDX1L promoter sequence
   Search SABiosciences Chromatin IP Primers for FDX1L

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FDX1L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.2   Ensembl cytogenetic band:  19p13.2   HGNC cytogenetic band: 19p13.2

FDX1L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FDX1L gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M010416:  view genomic region     (about GC identifiers)

Start:
10,416,103 bp from pter      End:
10,426,691 bp from pter
Size:
10,589 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ADXL_HUMAN, Q6P4F2 (See protein sequence)
Recommended Name: Adrenodoxin-like protein, mitochondrial precursor  
Size: 183 amino acids; 19521 Da
Cofactor: Binds 1 2Fe-2S cluster (By similarity)
Subcellular location: Mitochondrion. Mitochondrion matrix (By similarity)
1 PDB 3D structure from and Proteopedia for FDX1L:
2Y5C (3D)    

Explore the universe of human proteins at neXtProt for FDX1L: NX_Q6P4F2

Explore proteomics data for FDX1L at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6P4F2

  • FDX1L Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    FDX1L Protein Expression
    REFSEQ proteins: NP_001026904.1  
    ENSEMBL proteins: 
     ENSP00000377311   ENSP00000467188   ENSP00000441093  
    Reactome Protein details: Q6P4F2
    Human Recombinant Protein Products for FDX1L: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for FDX1L 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005759mitochondrial matrix TAS--

    FDX1L for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for FDX1L


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR012675 Beta-grasp_dom
     IPR001055 Adrenodoxin
     IPR018298 Adrenodoxin_Fe-S_BS
     IPR001041 2Fe-2S_ferredoxin-type

    Graphical View of Domain Structure for InterPro Entry Q6P4F2

    ProtoNet protein and cluster: Q6P4F2

    2 Blocks protein domains:
    IPB001041 Ferredoxin
    IPB001055 Adrenodoxin


    UniProtKB/Swiss-Prot: ADXL_HUMAN, Q6P4F2
    Similarity: Belongs to the adrenodoxin/putidaredoxin family
    Similarity: Contains 1 2Fe-2S ferredoxin-type domain


    FDX1L for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ADXL_HUMAN, Q6P4F2
    Function: Essential for heme A and Fe/S protein biosynthesis

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0009055electron carrier activity IEA--
    GO:0046872metal ion binding IEA--
    GO:0051536iron-sulfur cluster binding ----
    GO:00515372 iron, 2 sulfur cluster binding IEA--
         
    FDX1L for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for FDX1L 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FDX1L 
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    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate FDX1L:
    hsa-miR-1301
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for FDX1L About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Mitochondrial Iron-Sulfur Cluster Biogenesis
    Electron Transport from NADPH to Ferredoxin0.33
    Mitochondrial Iron-Sulfur Cluster Biogenesis0.33
    2Metabolism
    Metabolism0.40

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3        Reactome Pathways for FDX1L
        Mitochondrial Iron-Sulfur Cluster Biogenesis
    Metabolism
    Electron Transport from NADPH to Ferredoxin



    FDX1L for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FDX1L

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/7 Interacting proteins for FDX1L (Q6P4F23 ENSP000003773114) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ASNA1O436813, ENSP000003498874I2D: score=4 STRING: ENSP00000349887
    RPS6KA2Q153493I2D: score=2 
    UBE2G2P606043I2D: score=1 
    NFS1ENSP000003632054STRING: ENSP00000363205
    ISCUENSP000003106234STRING: ENSP00000310623
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0022900electron transport chain ----
    GO:0044281small molecule metabolic process TAS--
    GO:0055114oxidation-reduction process IEA--

    FDX1L for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FDX1L (ADXL)

    Search CenterWatch for drugs/clinical trials and news about FDX1L / ADXL

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FDX1L gene (2 alternative transcripts): 
    NM_080665.3  NM_001031734.2  

    Unigene Cluster for FDX1L:

    Ferredoxin 1-like
    Hs.654865  [show with all ESTs]
    Unigene Representative Sequence: AL524608
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000393708(uc002mny.1) ENST00000492239 ENST00000494368 ENST00000460631
    ENST00000343376 ENST00000453681 ENST00000486454 ENST00000541276(uc002mnx.1)

    miRNA
    Products:
         
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate FDX1L:
    hsa-miR-1301
    SwitchGear 3'UTR luciferase reporter plasmidFDX1L 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    GenScript: all cDNA clones in your preferred vector: FDX1L (NM_001031734)
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                         Customized lentivirus expression plasmids for stable overexpression of FDX1L 
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for FDX1L
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FDX1L
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FDX1L

    Additional mRNA sequence: 

    AK300568.1 BC010155.2 BC063460.1 

    11 DOTS entries:

    DT.212385  DT.121422214  DT.100782700  DT.100782699  DT.100024418  DT.95374300  DT.92420928  DT.121422192 
    DT.97841891  DT.99960882  DT.100037615 

    24/529 AceView cDNA sequences (see all 529):

    CB123158 C01301 BM926198 BQ101075 CK823014 AW237209 BQ066216 AI289404 
    BM738616 BC034409 BF724596 BC058903 BM460975 BX104157 BQ719653 CR597964 
    BC029904 BE257181 AI493502 BE395527 BM675275 CR590285 AW245043 BM715373 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FDX1L expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCCAGGCTCT
    FDX1L Expression
    About this image


    See FDX1L Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FDX1L

    SOURCE GeneReport for Unigene cluster: Hs.654865

    UniProtKB/Swiss-Prot: ADXL_HUMAN, Q6P4F2
    Tissue specificity: Widely expressed, with highest levels in testis, kidney and brain (at protein level)

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for FDX1L gene from 8/19 species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fdx1l1 , 5 ferredoxin 1-like1, 5 83.14(n)1
    83.91(a)1
      9 (7.70 cM)5
    681651  NM_001039824.21  NP_001034913.11 
     210675205 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.78542 Transcribed sequence with weak similarity to protein more 84.31(n)    CF376289.1 
    zebrafish
    (Danio rerio)
    Actinopterygii fdx1l1 ferredoxin 1-like 71.61(n)
    80.47(a)
      767726  NM_001076664.1  NP_001070132.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Fdxh1 Ferredoxin 63.91(n)
    61.65(a)
      39070  NM_001202146.1  NP_001189075.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_Y73F8A.271 Protein Y73F8A.27 58.63(n)
    58.16(a)
      178434  NM_070460.3  NP_502861.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes YAH11 Yah1p 53.94(n)
    45.45(a)
      855824   NP_015071.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons MFDX21 ferredoxin 2 52.01(n)
    51.72(a)
      827856  NM_118227.3  NP_193841.2 
    rice
    (Oryza sativa)
    Liliopsida Os09g04379001 hypothetical protein 52.87(n)
    50(a)
      4347157  NM_001069801.1  NP_001063266.1 


    ENSEMBL Gene Tree for FDX1L (if available)
    TreeFam Gene Tree for FDX1L (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FDX1L gene
    FDX12  ENSG000001678072  
    1 SIMAP similar gene for FDX1L using alignment to 1 protein entry:     ADXL_HUMAN:
    FDX1

    FDX1L for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/99 SNPs in FDX1L are shown (see all 99)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1495435531,2
    --10422294(+) GATGGG/TCTTGA 1 -- int10--------
    rs1922061761,2
    --10422298(+) GTCTTG/TATCTC 1 -- int10--------
    rs124628551,2
    C,F,A,H--10422323(+) TGCCCG/ACCTCA 1 -- int15Minor allele frequency- A:0.42NA 12
    rs124628571,2
    C,F,A,H--10422341(+) AAAGTG/CCTGGG 1 -- int14Minor allele frequency- C:0.50NA 10
    rs1840931461,2
    --10422356(+) CAGGCA/GTAAGC 1 -- int10--------
    rs345312861,2
    C--10422562(+) TTTTT-/T/TT  
            
    GAGGT
    1 -- int12NA 4
    rs43892481,2
    C--10422568(+) tgaggG/Tggagt 1 -- int10--------
    rs1125997361,2
    C,F--10422730(+) TAGTAG/TAGATG 1 -- int11Minor allele frequency- T:0.50NA 2
    rs1852809351,2
    --10422836(+) CCACCA/GCACCT 1 -- int10--------
    rs605387041,2
    C--10422849(+) TTTTT-/TGTAGA 1 -- int11Minor allele frequency- T:0.00NA 2

    HapMap Linkage Disequilibrium report for FDX1L (10416103 - 10426691 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for FDX1L:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2667969CNV Deletion23128226
    nsv911040CNV Loss21882294
    nsv911030CNV Loss21882294
    nsv911029CNV Loss21882294
    dgv3726n71CNV Loss21882294
    dgv3725n71CNV Loss21882294
    nsv470124CNV Gain18288195

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing FDX1L
    DNA2.0 Custom Variant and Variant Library Synthesis for FDX1L

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    FDX1L for disorders           About MalaCards
    OMIM gene information: 614585    OMIM disorders: --


    FDX1L for disorders           About GeneDecksing

    Genetic Association Database (GAD): FDX1L
    Human Genome Epidemiology (HuGE) Navigator: FDX1L (1 document)

    Export disorders for FDX1L gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FDX1L gene integrated from 9 sources:
    (articles sorted by number of sources associating them with FDX1L)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Humans possess two mitochondrial ferredoxins, Fdx1 an d Fdx2, with distinct roles in steroidogenesis, heme, and Fe/S cluster biosynth esis. (PubMed id 20547883)1, 2 Sheftel A.D....Lill R. (2010)
    2. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    4. Human ferredoxin-2 displays a unique conformational ch ange. (PubMed id 23208207)1 Qi W....Cowan J.A. (2013)
    5. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    6. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 112812 HGNC: 30546 AceView: ICAM3andMGC19604andRAVER1 Ensembl:ENSG00000267673 euGenes: HUgn112812
    ECgene: FDX1L H-InvDB: FDX1L

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FDX1L Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for FDX1L gene:
    Search GeneIP for patents involving FDX1L

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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