Aliases for FDPSP2 Gene
Aliases for FDPSP2 Gene
External Ids for FDPSP2 Gene
- HGNC: 3633
- Entrez Gene: 619190
- Ensembl: ENSG00000233980
Previous HGNC Symbols for FDPSP2 Gene
- FPSL2
- FDPSL2
- FDPSL2A
Previous GeneCards Identifiers for FDPSP2 Gene
- GC07M076101
Summaries for FDPSP2 Gene
GeneCards Summary for FDPSP2 Gene
FDPSP2 (Farnesyl Diphosphate Synthase Pseudogene 2) is a Pseudogene.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FDPSP2 Gene
Genomics for FDPSP2 Gene
Regulatory Elements for FDPSP2 Gene
Enhancers for FDPSP2 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH07G076469 | 1 | Ensembl ENCODE dbSUPER | 0.4 | +6.9 | 6903 | 0.9 | HDGF IKZF1 SIN3A | DTX2 FDPSP2 |
| GH07G076466 | 0.7 | Ensembl dbSUPER | 0.4 | +8.3 | 8300 | 0.2 | IRF9 CEBPB CEBPG | DTX2 FDPSP2 |
| GH07G076470 | 0.5 | dbSUPER | 0.4 | +12.0 | 12044 | 3.6 | JUNB MLLT1 ZBTB7A | UPK3B DTX2 FDPSP2 |
| GH07G076472 | 0.5 | dbSUPER | 0.4 | +11.4 | 11436 | 4.3 | MLLT1 ZBTB7A RBFOX2 | UPK3B DTX2 FDPSP2 |
| GH07G076465 | 0.4 | dbSUPER | 0.4 | +8.9 | 8945 | 0.6 | RBFOX2 | DTX2 FDPSP2 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FDPSP2 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for FDPSP2 Gene
- Chromosome:
- 7
- Start:
- 76,470,020 bp from pter
- End:
- 76,475,000 bp from pter
- Size:
- 4,981 bases
- Orientation:
- Minus strand
Genomic View for FDPSP2 Gene
Genes around FDPSP2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 7q11.23 by Ensembl
- 7q11.23 by Entrez Gene
- 7q11.23 by HGNC
FDPSP2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FDPSP2 Gene
Proteins for FDPSP2 Gene
Post-translational modifications for FDPSP2 Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for FDPSP2
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for FDPSP2
- Origene Custom Protein Services for FDPSP2
- Search GeneTex for Proteins for FDPSP2
Assay Products
No data available for DME Specific Peptides for FDPSP2 Gene
Domains & Families for FDPSP2 Gene
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for FDPSP2 Gene
Function for FDPSP2 Gene
Phenotypes for FDPSP2 Gene
- GenomeRNAi human phenotypes for FDPSP2:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Search ViGene Biosciences for FDPSP2
CRISPR Products
- Browse CRISPR knockouts for FDPSP2
miRNA Products
- Search ViGene Biosciences for FDPSP2
Inhibitory RNA Products
- Search ViGene Biosciences for FDPSP2
Cell Line Products
- Search ViGene Biosciences for FDPSP2
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FDPSP2 Gene
Localization for FDPSP2 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FDPSP2 Gene
Drugs & Compounds for FDPSP2 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Alendronate | Approved | Pharma | Inhibition, Inhibitor | Bone resorption inhibitor, Osteoclast function modifiers (important in bone metastasis) | 162 |
(1) ApexBio Compounds for FDPSP2 Gene
| Compound | Action | Cas Number |
|---|---|---|
| Alendronate | Bone resorption inhibitor | 121268-17-5 |
Drug Products
- ApexBio compounds for FDPSP2
Transcripts for FDPSP2 Gene
mRNA/cDNA for FDPSP2 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for FDPSP2
miRNA Products
- Search ViGene Biosciences for FDPSP2
Inhibitory RNA Products
- Search ViGene Biosciences for FDPSP2
Flow Cytometry Products
Expression for FDPSP2 Gene
mRNA differential expression in normal tissues according to GTEx for FDPSP2 Gene
This gene is overexpressed in Esophagus - Mucosa (x6.0), Whole Blood (x4.8), and Minor Salivary Gland (x4.2).
NURSA nuclear receptor signaling pathways regulating expression of FDPSP2 Gene:
FDPSP2Primer Products
-
OriGene qPCR primer pairs for FDPSP2
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FDPSP2 Gene
Orthologs for FDPSP2 Gene
No data available for Orthologs for FDPSP2 Gene
Paralogs for FDPSP2 Gene
No data available for Paralogs for FDPSP2 Gene
Variants for FDPSP2 Gene
| SNP ID | Clin | Chr 07 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1001256708 | -- | 76,469,559(+) | GGCTA(A/C)TTTTT | intron-variant, downstream-variant-500B | |
| rs1001858343 | -- | 76,472,576(+) | CCCCC(A/C)TCAGC | intron-variant, nc-transcript-variant | |
| rs1001924934 | -- | 76,472,102(+) | GGACT(A/G)CTGTC | intron-variant, nc-transcript-variant | |
| rs1002934825 | -- | 76,474,498(+) | TTCAT(C/G)TTCTC | intron-variant, nc-transcript-variant | |
| rs1003944336 | -- | 76,476,232(+) | GGCAT(A/C)ATTAG | intron-variant, upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv120n16 | CNV | deletion | 17901297 |
| dgv1218e199 | CNV | deletion | 23128226 |
| dgv21n31 | CNV | gain | 19718026 |
| dgv232e55 | CNV | gain | 17911159 |
| dgv233e55 | CNV | loss | 17911159 |
| dgv234e55 | CNV | gain | 17911159 |
| dgv235e55 | CNV | loss | 17911159 |
| dgv6470n100 | CNV | loss | 25217958 |
| dgv6471n100 | CNV | gain | 25217958 |
| dgv6472n100 | CNV | loss | 25217958 |
| dgv6473n100 | CNV | gain | 25217958 |
| dgv6474n100 | CNV | loss | 25217958 |
| dgv6475n100 | CNV | gain | 25217958 |
| dgv6476n100 | CNV | gain | 25217958 |
| esv23516 | CNV | gain | 19812545 |
| esv2422494 | CNV | duplication | 17116639 |
| esv2734687 | CNV | deletion | 23290073 |
| esv2761124 | CNV | gain | 21179565 |
| esv2764008 | CNV | gain+loss | 21179565 |
| esv33074 | CNV | gain | 17666407 |
| nsv1034692 | CNV | gain+loss | 25217958 |
| nsv428174 | CNV | gain | 18775914 |
| nsv471446 | CNV | gain | 19718026 |
| nsv482106 | CNV | gain | 20164927 |
| nsv517634 | CNV | gain+loss | 19592680 |
| nsv528969 | CNV | gain | 19592680 |
| nsv607585 | CNV | gain | 21841781 |
| nsv7403 | OTHER | inversion | 18451855 |
| nsv970894 | CNV | duplication | 23825009 |
| nsv981537 | CNV | duplication | 23825009 |
Relevant External Links for FDPSP2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- FDPSP2
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for FDPSP2 Gene
Disorders for FDPSP2 Gene
Relevant External Links for FDPSP2
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- FDPSP2
No disorders were found for FDPSP2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FDPSP2 Gene
Publications for FDPSP2 Gene
- Dispersed family of human genes with sequence similarity to farnesyl pyrophosphate synthetase. (PMID: 2613235) Heinzmann C. … Lusis A.J. (Genomics 1989) 2 3 64
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
- Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PMID: 10737800) Dias Neto E. … Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3 64
Products for FDPSP2 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for FDPSP2
- Origene Custom Protein Services for FDPSP2
- Browse OriGene Inhibitory RNA Products For FDPSP2
- OriGene qPCR primer pairs for FDPSP2
- Browse CRISPR knockouts for FDPSP2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For FDPSP2
- GenScript: Custom all cDNA clones Services for FDPSP2
- GenScript Custom Purified and Recombinant Proteins Services for FDPSP2
- GenScript Custom Assay Services for FDPSP2
- GenScript Custom overexpressing Cell Line Services for FDPSP2
- Browse GenScript CRISPR for FDPSP2
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for FDPSP2
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ApexBio compounds for FDPSP2
- Cyagen custom Knockout/knockin (KOKI) mouse models for FDPSP2
- VectorBuilder custom plasmid, inducible vectors for FDPSP2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FDPSP2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FDPSP2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer