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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FCRLA Gene

protein-coding   GIFtS: 52
GCID: GC01P161676

Fc Receptor-Like A

(Previous name: Fc receptor-like and mucin-like 1)
(Previous symbol: FCRLM1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Fc Receptor-Like A1 2     FCRX2 3
FCRLM11 2 3     FCRLX2
FREB2 3 5     FCRLb2
Fc Receptor-Like And Mucin-Like 11 2     FCRLc12
Fc Receptor Homolog Expressed In B-Cells2 3     FCRLc22
Fc Receptor-Like And Mucin-Like Protein 12 3     FCRLd2
Fc Receptor-Like Protein2 3     FCRLe2
Fc Receptor-Related Protein X2 3     Fc Receptor Homolog Expressed In B Cells (FREB)2
FCRL2 3     Fc Receptor Related Protein X2
FCRL12 3     FcRX3

External Ids:    HGNC: 185041   Entrez Gene: 848242   Ensembl: ENSG000001321857   OMIM: 6068915   UniProtKB: Q7L5133   

Export aliases for FCRLA gene to outside databases

Previous GC identifers: GC01P159944 GC01P132921


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FCRLA Gene:
This gene encodes a protein similar to receptors for the Fc fragment of gamma immunoglobulin (IgG). These
receptors, referred to as FCGRs, mediate the destruction of IgG-coated antigens and of cells induced by
antibodies. This encoded protein is selectively expressed in B cells, and may be involved in their development.
This protein may also be involved in the development of lymphomas. Multiple alternatively spliced transcript
variants that encode different protein isoforms have been described for this gene. (provided by RefSeq, Aug 2011)

GeneCards Summary for FCRLA Gene: 
FCRLA (Fc receptor-like A) is a protein-coding gene. Diseases associated with FCRLA include diffuse large b-cell lymphoma, and tonsillitis. An important paralog of this gene is FCGR1B.

UniProtKB/Swiss-Prot: FCRLA_HUMAN, Q7L513
Function: May be implicated in B-cell differentiation and lymphomagenesis

Gene Wiki entry for FCRLA Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FCRLA gene promoter:
         STAT5B   STAT1   Tal-1   POU3F1   MyoD   LCR-F1   Roaz   YY1   E47   FOXL1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFCRLA promoter sequence
   Search SABiosciences Chromatin IP Primers for FCRLA

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FCRLA


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q23.3   Ensembl cytogenetic band:  1q23.3   HGNC cytogenetic band: 1q23.3

FCRLA Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FCRLA gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P161676:  view genomic region     (about GC identifiers)

Start:
161,676,762 bp from pter      End:
161,684,142 bp from pter
Size:
7,381 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: FCRLA_HUMAN, Q7L513 (See protein sequence)
Recommended Name: Fc receptor-like A precursor  
Size: 359 amino acids; 38927 Da
Subunit: Monomer or homodimer; disulfide-linked
Subcellular location: Secreted (Probable). Cytoplasm
Caution: It is uncertain whether Met-1 or Met-8 is the initiator
1 PDB 3D structure from and Proteopedia for FCRLA:
4HWN (3D)    
Secondary accessions: A0N0M1 Q5VXA1 Q5VXA2 Q5VXA3 Q5VXA4 Q5VXB0 Q8NEW4 Q8WXH3 Q96PC6 Q96PJ0
Q96PJ1 Q96PJ2 Q96PJ4 Q9BR57
Alternative splicing: 9 isoforms:  Q7L513-1   Q7L513-2   Q7L513-3   Q7L513-4   Q7L513-5   Q7L513-6   Q7L513-7   Q7L513-8   
Q7L513-9   

Explore the universe of human proteins at neXtProt for FCRLA: NX_Q7L513

Explore proteomics data for FCRLA at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q7L513

  • FCRLA Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    FCRLA Protein Expression
    REFSEQ proteins (7 alternative transcripts): 
    NP_001171795.1  NP_001171796.1  NP_001171799.1  NP_001171800.1  NP_001171801.1  NP_001171802.1  NP_116127.3  

    ENSEMBL proteins: 
     ENSP00000236938   ENSP00000356934   ENSP00000294798   ENSP00000309596   ENSP00000294796  
     ENSP00000356930   ENSP00000356927   ENSP00000356936   ENSP00000439838   ENSP00000442870  
     ENSP00000356926   ENSP00000344808   ENSP00000446380  

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    Browse Sino Biological Cell Lysates 
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    Cloud-Clone Corp. Proteins for FCRLA 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0005737cytoplasm IDA15815692

    FCRLA for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    IGD: Immunoglobulin superfamily / Immunoglobulin-like domain containing

    3 InterPro protein domains:
     IPR013783 Ig-like_fold
     IPR007110 Ig-like_dom
     IPR003599 Ig_sub

    Graphical View of Domain Structure for InterPro Entry Q7L513

    ProtoNet protein and cluster: Q7L513

    1 Blocks protein domain: IPB003599 Immunoglobulin subtype

    UniProtKB/Swiss-Prot: FCRLA_HUMAN, Q7L513
    Similarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains


    FCRLA for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FCRLA_HUMAN, Q7L513
    Function: May be implicated in B-cell differentiation and lymphomagenesis

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    FCRLA for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for FCRLA:
     Decreased number of cells in m  Small cells 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Fcrla):
     immune system 

    FCRLA for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for FCRLA 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for FCRLA

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FCRLA 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FCRLA 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FCRLA
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate FCRLA:
    hsa-miR-1286 hsa-miR-3672
    SwitchGear 3'UTR luciferase reporter plasmidFCRLA 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector (see all 7): FCRLA (NM_032738)
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FCRLA


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FCRLA

    1 Interacting protein for FCRLA (Q7L5133) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TRAF2Q129333I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030154cell differentiation IEA--

    FCRLA for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FCRLA

    Search CenterWatch for drugs/clinical trials and news about FCRLA

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FCRLA gene (7 alternative transcripts): 
    NM_001184866.1  NM_001184867.1  NM_001184870.1  NM_001184871.1  NM_001184872.1  NM_001184873.1  NM_032738.3  

    Unigene Cluster for FCRLA:

    Fc receptor-like A
    Hs.266331  [show with all ESTs]
    Unigene Representative Sequence: NM_001184866
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000236938 ENST00000367957 ENST00000465403 ENST00000349527 ENST00000309691
    ENST00000294796 ENST00000367953 ENST00000367950 ENST00000470841 ENST00000367959(uc001gbe.3)
    ENST00000546024(uc001gbf.3) ENST00000540521(uc009wuo.3 uc001gbg.3)
    ENST00000367949(uc009wup.3) ENST00000350710(uc009wuq.3) ENST00000540926(uc001gbd.3)

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FCRLA
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate FCRLA:
    hsa-miR-1286 hsa-miR-3672
    SwitchGear 3'UTR luciferase reporter plasmidFCRLA 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FCRLA

    Additional mRNA sequence: 

    AF329489.1 AF329491.1 AF329493.1 AF329494.1 AF329495.1 AF390036.1 AF426461.1 AF531423.1 
    AY091642.2 AY358348.1 BC006521.2 

    7 DOTS entries:

    DT.100798878  DT.100816700  DT.101983413  DT.447471  DT.95191684  DT.121362313  DT.95191706 

    24/146 AceView cDNA sequences (see all 146):

    BM015660 CR592613 BQ061343 BM477199 CR612235 BG759709 AW402824 BQ064967 
    BC006521 BQ061950 BU154998 AI470743 AW403434 CD695339 AI434284 AF531423 
    BQ006753 BX112608 NM_032738 BM455468 AW575245 BU160454 BP338143 AF329489 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for FCRLA (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d · 5e
    SP1:                                -                                                   
    SP2:                                -                 -                                 
    SP3:                                -           -                                       
    SP4:                                -     -     -                                       
    SP5:                                -           -     -                                 


    ECgene alternative splicing isoforms for FCRLA

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FCRLA expression in normal human tissues (normalized intensities)      FCRLA embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATCTCACTTA
    FCRLA Expression
    About this image


    FCRLA expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             Small Pre B-Cells Hematopoietic Bone Marrow
     
     Lymph (Hematopoietic System)
             LYMPH NODE   
     
     Spleen (Hematopoietic System)
             Conventional Dendritic Cells I Spleen

     -- (Integumentary System)
             SKIN   

    See FCRLA Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FCRLA

    SOURCE GeneReport for Unigene cluster: Hs.266331

    UniProtKB/Swiss-Prot: FCRLA_HUMAN, Q7L513
    Tissue specificity: Expressed specifically in primary and secondary lymphoid tissues like lymph node, spleen and
    tonsil. Specifically expressed in B-cells with a high level in normal germinal center B-cells, centroblasts and
    in a subset of diffuse large B-cell lymphomas. Highly expressed in bone marrow B-cells and weakly in earlier B
    lineage cells. Expressed in pre-germinal and germinal center B-cells in secondary lymphoid tissues. Also
    expressed in melanoma and melanocytes

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FCRLA

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of human and mouse.

    Orthologs for FCRLA gene from 1/7 species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fcrla1 , 5 Fc receptor-like A1, 5 78.6(n)1
    71.89(a)1
      1 (77.65 cM)5
    987521  NM_145141.21  NP_660123.11 
     1709175765 


    ENSEMBL Gene Tree for FCRLA (if available)
    TreeFam Gene Tree for FCRLA (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FCRLA gene
    FCGR1B2  FCGR2B2  FCRLB2  FCGR3B2  FCRL22  FCRL12  FCRL52  FCRL42  
    FCGR2A2  FCGR1A2  FCGR3A2  FCRL32  FCER1A2  FCRL62  
    4 SIMAP similar genes for FCRLA using alignment to 9 protein entries:     FCRLA_HUMAN (see all proteins):
    DKFZp686L20250    FCGR1A    FCRL6    FCRLB

    FCRLA for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/277 SNPs in FCRLA are shown (see all 277)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1154711401,2
    C,F--161674878(+) CAGTGG/AGGTCC 7 -- us2k11Minor allele frequency- A:0.03WA 118
    rs559607101,2
    C,F--161675110(+) ATCCAG/ACACTT 7 -- us2k15Minor allele frequency- A:0.12WA CSA NA 244
    rs107999111,2
    C,F,A--161675155(+) AGATCG/AAGACC 7 -- us2k13Minor allele frequency- A:0.33NA WA 6
    rs1832425271,2
    --161675186(+) ACCCCA/GTCTCT 7 -- us2k10--------
    rs1402401651,2
    --161675251(+) TACTCA/GGGAGG 7 -- us2k10--------
    rs1876366111,2
    --161675262(+) CTGAGA/GCAGGA 7 -- us2k10--------
    rs612134021,2
    C--161675354(+) ATCTC-/AAAAAA 7 -- us2k11Minor allele frequency- A:0.00CSA 2
    rs120367231,2
    C,F--161675367(+) aaaaaT/AaTTAT 7 -- us2k1 tfbs3 trp31Minor allele frequency- A:0.50NA 2
    rs1835792201,2
    --161675470(+) TCAACC/TACCCC 7 -- us2k10--------
    rs1477286691,2
    --161675577(+) TTATGC/TCCGTG 7 -- us2k10--------

    HapMap Linkage Disequilibrium report for FCRLA (161676762 - 161684142 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for FCRLA:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv524449CNV Loss19592680
    nsv428257CNV Loss18775914
    nsv464184CNV Gain19166990
    esv33393CNV Gain+Loss17666407
    dgv138e1CNV Complex17122850
    dgv135e1CNV Complex17122850
    dgv133e1CNV Complex17122850

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606891    OMIM disorders: --

    8 diseases for FCRLA:    About MalaCards
    diffuse large b-cell lymphoma    tonsillitis    b-cell lymphomas    hepatitis b
    rheumatoid arthritis    arthritis    melanoma    hepatitis


    FCRLA for disorders           About GeneDecksing

    Genetic Association Database (GAD): FCRLA
    Human Genome Epidemiology (HuGE) Navigator: FCRLA (1 document)

    Export disorders for FCRLA gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FCRLA gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with FCRLA)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. FCRL, a novel member of the leukocyte Fc receptor family possesses unique structural features. (PubMed id 11754007)1, 2, 3 Mechetina L.V....Taranin A.V. (2002)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    3. Novel melanoma antigen, FCRL/FREB, identified by cDNA profile comparison using DNA chip are immunogenic in multiple melanoma patients. (PubMed id 15551350)1, 2 Inozume T.... Kawakami Y. (2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (2004)
    6. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    7. Definition of an Fc receptor-related gene (FcRX) expressed in human and mouse B cells. (PubMed id 12202404)1, 2 Davis R.S.... Burrows P.D. (2002)
    8. An unusual Fc receptor-related protein expressed in human centroblasts. (PubMed id 11891275)1, 2 Facchetti F.... Colonna M. (2002)
    9. Host-microbe interactions have shaped the genetic arch itecture of inflammatory bowel disease. (PubMed id 23128233)1 Jostins L....Cho J.H. (2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84824 HGNC: 18504 AceView: FREB Ensembl:ENSG00000132185 euGenes: HUgn84824
    ECgene: FCRLA H-InvDB: FCRLA

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FCRLA Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for FCRLA gene:
    Search GeneIP for patents involving FCRLA

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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