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FCRL5 Gene

protein-coding   GIFtS: 52
GCID: GC01M157477

Fc Receptor-Like 5

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Fc Receptor-Like 51 2     CD307e2
IRTA22 3 5     PRO8202
Fc Receptor Homolog 52 3     Fc Receptor-Like Protein 52
FcR-Like Protein 52 3     Immunoglobulin Superfamily Receptor Translocation Associated 2 (IRTA2)2
Immune Receptor Translocation-Associated Protein 22 3     FcRH53
BXMAS12 3     FcRL53
FCRH52 3     CD307e Antigen3
CD3072     

External Ids:    HGNC: 185081   Entrez Gene: 834162   Ensembl: ENSG000001432977   OMIM: 6058775   UniProtKB: Q96RD93   

Export aliases for FCRL5 gene to outside databases

Previous GC identifers: GC01M154297 GC01M155752 GC01M128841


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for FCRL5 Gene:
This gene encodes a member of the immunoglobulin receptor superfamily and the Fc-receptor like family. This gene
and several other Fc receptor-like gene members are clustered on the long arm of chromosome 1. The encoded
protein is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains. This gene is
implicated in B cell development and lymphomagenesis. Alternatively spliced transcript variants encoding
different isoforms have been identified. (provided by RefSeq, Sep 2010)

GeneCards Summary for FCRL5 Gene:
FCRL5 (Fc receptor-like 5) is a protein-coding gene. Diseases associated with FCRL5 include hairy cell leukemia, and mantle cell lymphoma. An important paralog of this gene is FCGR1B.

UniProtKB/Swiss-Prot: FCRL5_HUMAN, Q96RD9
Function: May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be
useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells

Gene Wiki entry for FCRL5 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NC_018912.2  NT_004487.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the FCRL5 gene promoter:
         AML1a   GCNF   LUN-1   RORalpha1   POU2F1   POU2F1a   FOXJ2 (long isoform)   GCNF-1   FOXJ2   GCNF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFCRL5 promoter sequence
   Search Chromatin IP Primers for FCRL5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FCRL5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21   Ensembl cytogenetic band:  1q23.1   HGNC cytogenetic band: 1q21

FCRL5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FCRL5 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M157477:  view genomic region     (about GC identifiers)

Start:
157,483,167 bp from pter      End:
157,522,310 bp from pter
Size:
39,144 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: FCRL5_HUMAN, Q96RD9 (See protein sequence)
Recommended Name: Fc receptor-like protein 5 precursor  
Size: 977 amino acids; 106437 Da
Secondary accessions: A0N0M2 B7WNT9 B7WP94 Q495Q2 Q495Q4 Q5VYK9 Q6UY46
Alternative splicing: 5 isoforms:  Q96RD9-1   Q96RD9-2   Q96RD9-3   Q96RD9-4   Q96RD9-5   

Explore the universe of human proteins at neXtProt for FCRL5: NX_Q96RD9

Explore proteomics data for FCRL5 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn383
  • Modification sites at PhosphoSitePlus

  • See FCRL5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001182317.1  NP_112571.2  

    ENSEMBL proteins: 
     ENSP00000354691   ENSP00000357173   ENSP00000357172   ENSP00000349434   ENSP00000357174  
     ENSP00000357171  

    FCRL5 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    CD: CD molecules
    IGD: Immunoglobulin superfamily / Immunoglobulin-like domain containing

    4 InterPro protein domains:
     IPR003598 Ig_sub2
     IPR013783 Ig-like_fold
     IPR007110 Ig-like_dom
     IPR003599 Ig_sub

    Graphical View of Domain Structure for InterPro Entry Q96RD9

    ProtoNet protein and cluster: Q96RD9

    2 Blocks protein domains:
    IPB003598 Immunoglobulin C-2 type
    IPB003599 Immunoglobulin subtype


    UniProtKB/Swiss-Prot: FCRL5_HUMAN, Q96RD9
    Domain: Contains 2 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based
    inhibitor motif (ITIM) (By similarity)
    Similarity: Contains 8 Ig-like C2-type (immunoglobulin-like) domains


    FCRL5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FCRL5_HUMAN, Q96RD9
    Function: May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be
    useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    FCRL5 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FCRL5
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    SwitchGear 3'UTR luciferase reporter plasmidFCRL5 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    FCRL5_HUMAN, Q96RD9: Cell membrane; Single-pass type I membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0016021integral component of membrane IEA--
    GO:0043235receptor complex IDA--

    FCRL5 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FCRL5
    Interactions:

        Search GeneGlobe Interaction Network for FCRL5

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FCRL5



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for FCRL5 gene (2 alternative transcripts): 
    NM_001195388.1  NM_031281.2  

    Unigene Cluster for FCRL5:

    Fc receptor-like 5
    Hs.415950  [show with all ESTs]
    Unigene Representative Sequence: NM_031281
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000462218 ENST00000361835(uc001fqu.3 uc009wsm.3) ENST00000461387
    ENST00000497286 ENST00000483875 ENST00000368190(uc010phv.1 uc010phw.1)
    ENST00000368189(uc001fqv.1 uc010phx.2) ENST00000481082 ENST00000356953
    ENST00000368191 ENST00000368188
    miRNA
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    8 qRT-PCR Assays for microRNAs that regulate FCRL5:
    hsa-miR-1298 hsa-miR-3155 hsa-miR-1291 hsa-miR-484 hsa-miR-664 hsa-miR-4316 hsa-miR-141* hsa-miR-3155b
    SwitchGear 3'UTR luciferase reporter plasmidFCRL5 3' UTR sequence
    Inhib. RNA
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      QuantiFast Probe-based Assays in human, mouse, rat FCRL5

    Additional mRNA sequence: 

    AF343662.1 AF343663.1 AF343664.1 AF343665.1 AF369794.2 AF397453.1 AK090475.1 AK300010.1 
    AK301356.1 AK311561.1 AY358085.1 BC101066.2 BC101067.1 BC101068.2 BC101069.2 

    7 DOTS entries:

    DT.301929  DT.97838658  DT.97838659  DT.100741381  DT.86845826  DT.121450283  DT.99947136 

    Selected AceView cDNA sequences (see all 81):

    AW614462 AW452574 AA721628 AA642412 AA813901 AA730057 AA732643 AY358085 
    AA747579 AI377702 AW241983 AA827165 AI367121 CD724126 AF343664 AL832301 
    AI433612 CD633059 CD633069 AK090423 CD724079 AI347054 AF397453 AF343665 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for FCRL5 (see all 9)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b ^ 12 ^ 13 ^ 14a · 14b ^ 15a · 15b ^ 16
    SP1:        -                                               -     -                 -     -           -                                   -               
    SP2:        -                                               -     -                 -     -           -                       -           -               
    SP3:                                                                                -     -           -                                   -               
    SP4:        -                                               -     -                                                                                       
    SP5:                                                                                                                                      -               


    ECgene alternative splicing isoforms for FCRL5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FCRL5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CATTTATCAT
    FCRL5 Expression
    About this image


    FCRL5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Blood (Hematopoietic System)
             Mature B-Cells Peripheral Blood
    FCRL5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FCRL5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.415950

    UniProtKB/Swiss-Prot: FCRL5_HUMAN, Q96RD9
    Tissue specificity: Expressed in marginal zone B-cells, immunoblasts, tonsillar germinal center centrocytes and in
    the intraepithelial and interfollicular regions of the tonsil. Expressed in many lymphoma cell lines and on hairy
    cell leukemia cells. Isoform 1, isoform 3, isoform 4 and isoform 5 are detected in lymph node, spleen, bone
    marrow, and small intestine with preponderance of isoform 3. Expressed in mature and memory B-cells and
    down-regulated in germinal center cells (at protein level)

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for FCRL5 gene from Selected species (see all 6)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fcrl51 Fc receptor-like 5 62.82(n)
    44.66(a)
      329693  NM_183222.3  NP_899045.3 
    chicken
    (Gallus gallus)
    Aves FCRL26
    Gallus gallus Fc receptor-like 2 (FCRL2), mRNA.
    30(a)
    1 → many
    25(1587904-1591630)


    ENSEMBL Gene Tree for FCRL5 (if available)
    TreeFam Gene Tree for FCRL5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FCRL5 gene
    FCGR1B2  FCGR2B2  FCRLB2  FCGR3B2  FCRL22  FCRL12  FCRLA2  FCRL42  
    FCGR2A2  FCGR1A2  FCGR3A2  FCRL32  FCER1A2  FCRL62  
    10 SIMAP similar genes for FCRL5 using alignment to 3 protein entries:     FCRL5_HUMAN (see all proteins):
    FLJ00333    FCRL2    FCRL4    FCGR2B    FCGR1A    FCRL1
    FCGR3B    Fc-gamma receptor IIIB    FCRLB    FCGR3A

    FCRL5 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for FCRL5
    PGOHUM00000244290 PGOHUM00000245023


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FCRL5 (see all 1111)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0355144
    A breast cancer sample4--see VAR_0355142 S C mis40--------
    rs718171861,2
    C--157483520(+) TCCCA-/ATGAGA 2 -- ut310--------
    rs3718767021,2
    C--157489941(+) TTCGT-/GGGGGG 2 -- int10--------
    rs608188671,2
    C,F--157498679(+) TAGACA/TTTGGT 2 -- int11Minor allele frequency- T:0.01WA 118
    rs568013761,2
    C--157498933(+) GGGCAA/GAGGAC 2 -- int10--------
    rs769155371,2
    C,F--157498970(+) TATACG/AAACAG 2 -- int13Minor allele frequency- A:0.40WA NA CSA 5
    rs43811761,2
    C--157499079(+) aaaacA/Caaaaa 2 -- int11Minor allele frequency- C:0.00NA 2
    rs1114204711,2
    C--157499385(+) TACGC-/ATGT  
            
    GTGTG
    2 -- int11Minor allele frequency- ATGT:0.00CSA 2
    rs109085761,2
    C,F,A,H--157499386(+) acgcaC/Tgtgtg 2 -- int14Minor allele frequency- T:0.29NA 14
    rs722292951,2
    C--157499386(+) ACGCA-/TGTGTGT 2 -- int10--------

    HapMap Linkage Disequilibrium report for FCRL5 (157483167 - 157522310 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for FCRL5:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2718507CNV Deletion23290073
    nsv3143CNV Insertion18451855
    esv275399CNV Loss21479260
    nsv831681CNV Gain+Loss17160897

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605877    OMIM disorders: --

    UniProtKB/Swiss-Prot: FCRL5_HUMAN, Q96RD9
  • Note=A chromosomal aberration involving FCRL5 has been found in cell lines with 1q21 abnormalities
    derived from Burkitt lymphoma. Duplication dup(1)(q21q32)

  • 19 diseases for FCRL5:    
    About MalaCards
    hairy cell leukemia    mantle cell lymphoma    chronic lymphocytic leukemia    ankylosing spondylitis
    b-cell chronic lymphocytic leukemia    spondylitis    tonsillitis    sinusitis
    burkitt's lymphoma    multiple myeloma    t-cell leukemia    graves' disease
    myeloma    lymphoblastic leukemia    breast and colorectal cancer    leukemia
    hepatitis b    hepatitis    colorectal cancer


    FCRL5 for disorders           About GeneDecksing

    2 Novoseek inferred disease relationships for FCRL5 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    leukemia hairy cell 71.9 1 15671532 (1)
    lymphoma 27.1 5 15671532 (2), 17051241 (2)

    Genetic Association Database (GAD): FCRL5
    Human Genome Epidemiology (HuGE) Navigator: FCRL5 (4 documents)

    Export disorders for FCRL5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FCRL5 gene, integrated from 10 sources (see all 31):
    (articles sorted by number of sources associating them with FCRL5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. IRTA1 and IRTA2, novel immunoglobulin superfamily receptors expressed in B cells and involved in chromosome 1q21 abnormalities in B cell malignancy. (PubMed id 11290337)1, 2, 3 Hatzivassiliou G.... Dalla-Favera R. (Immunity 2001)
    2. IRTAs: a new family of immunoglobulin-like receptors differentially expressed in B cells. (PubMed id 11929751)1, 2, 9 Miller I....Dalla-Favera R. (Blood 2002)
    3. Association of Fc receptor-like 5 (FCRL5) with Graves' disease is secondary to the effect of FCRL3. (PubMed id 20626413)1, 4 Simmonds M.J....Gough S.C. (Clin. Endocrinol. (Oxf) 2010)
    4. A single-nucleotide polymorphism marker within the FCRL5 gene and HLA-B27 positive Han Chinese ankylosing spondylitis patients. (PubMed id 19775371)1, 4 Tang X....Xu J. (Tissue Antigens 2009)
    5. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    8. BXMAS1 identifies a cluster of homologous genes differentially expressed in B cells. (PubMed id 11453668)1, 2 Nakayama Y.... Bothwell A.L.M. (Biochem. Biophys. Res. Commun. 2001)
    9. Identification of a family of Fc receptor homologs with preferential B cell expression. (PubMed id 11493702)1, 2 Davis R.S.... Cooper M.D. (Proc. Natl. Acad. Sci. U.S.A. 2001)
    10. Altered gene expression upon BCR cross-linking in Burkitt's lymphoma B cell line. (PubMed id 11027651)1, 3 Nakayama Y....Bothwell A.L. (Biochem. Biophys. Res. Commun. 2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 83416 HGNC: 18508 AceView: IRTA2 Ensembl:ENSG00000143297 euGenes: HUgn83416
    ECgene: FCRL5 H-InvDB: FCRL5

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for FCRL5 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for FCRL5 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FCRL5 gene:
    Search GeneIP for patents involving FCRL5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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