Aliases for FCRL3 Gene
Aliases for FCRL3 Gene
External Ids for FCRL3 Gene
- HGNC: 18506
- Entrez Gene: 115352
- Ensembl: ENSG00000160856
- OMIM: 606510
- UniProtKB: Q96P31
Previous GeneCards Identifiers for FCRL3 Gene
- GC01M154460
- GC01M155912
- GC01M157646
- GC01M129005
Summaries for FCRL3 Gene
-
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains immunoreceptor-tyrosine activation motifs and immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain and may play a role in regulation of the immune system. Mutations in this gene have been associated with rheumatoid arthritis, autoimmune thyroid disease, and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
GeneCards Summary for FCRL3 Gene
FCRL3 (Fc Receptor Like 3) is a Protein Coding gene. Diseases associated with FCRL3 include Neuromyelitis Optica and Rheumatoid Arthritis. Among its related pathways are B Cell Development Pathways. An important paralog of this gene is FCRL5.
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FCRL3 Gene
Genomics for FCRL3 Gene
Regulatory Elements for FCRL3 Gene
Enhancers for FCRL3 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH01G157721 | 1.2 | Ensembl ENCODE dbSUPER | 24 | -23.4 | -23449 | 6.4 | CTCF ZBTB7B RAD21 RELA GATA3 POLR2A SMC3 RELB IKZF2 ZNF654 | FCRL3 ENSG00000227217 FCRL2 FCRL1 VDAC1P9 SONP1 |
| GH01G157695 | 0.8 | ENCODE dbSUPER | 20.6 | +2.1 | 2051 | 7.7 | ZNF366 MTA2 ZNF512 FOS ATF2 TBX21 | FCRL3 ENSG00000227217 |
| GH01G157773 | 0.6 | ENCODE | 18.1 | -73.2 | -73207 | 1.5 | CTCF TARDBP TRIM22 NBN SMC3 RAD21 SPI1 | FCRL3 FCRL1 FCRL5 FCRL2 PIR43091 |
| GH01G157595 | 0.8 | ENCODE | 10.8 | +105.5 | 105450 | 0.1 | TBL1XR1 WRNIP1 BMI1 CBX5 EED ETV6 RELB IKZF2 CREM CHD2 | FCRL5 ENSG00000227217 FCRL3 FCRL2 FCRL1 FCRL4 |
| GH01G157733 | 0.7 | ENCODE dbSUPER | 11.5 | -33.6 | -33591 | 2.1 | PKNOX1 TBX21 | FCRL3 FCRL2 ENSG00000227217 FCRL1 VDAC1P9 PIR43091 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FCRL3 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the FCRL3 gene promoter:
Regulatory Element Products
Genomic Location for FCRL3 Gene
- Chromosome:
- 1
- Start:
- 157,674,321 bp from pter
- End:
- 157,700,985 bp from pter
- Size:
- 26,665 bases
- Orientation:
- Minus strand
Genomic View for FCRL3 Gene
Genes around FCRL3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1q23.1 by Ensembl
- 1q23.1 by Entrez Gene
- 1q23.1 by HGNC
FCRL3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FCRL3 Gene
Proteins for FCRL3 Gene
-
Protein details for FCRL3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96P31-FCRL3_HUMAN
- Recommended name:
- Fc receptor-like protein 3
- Protein Accession:
- Q96P31
- A0N0M4
- A8MTH7
- D3DVD2
- Q5VXZ8
- Q8N6S2
- Q96LA4
- Q96P27
- Q96P28
- Q96P29
- Q96P30
Protein attributes for FCRL3 Gene
- Size:
- 734 amino acids
- Molecular mass:
- 80856 Da
- Quaternary structure:
-
- Interacts with PTPN6, PTPN11, SYK and ZAP70.
Protein Expression for FCRL3 Gene
Post-translational modifications for FCRL3 Gene
- Phosphorylated on cytoplasmic tyrosines; required for interaction with protein tyrosine phosphatases and protein tyrosine kinases.
- Glycosylation at isoforms=2, 3, 6, 7561
- Modification sites at PhosphoSitePlus
Other Protein References for FCRL3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for FCRL3 (FCRL3/FcRH3)
- Novus Biologicals Antibodies for FCRL3
-
Abcam antibodies for FCRL3
- Invitrogen Antibodies for FCRL3
- antibodies-online Antibodies for FCRL3: See all 1
- GeneTex FCRL3 antibody for FCRL3
-
Santa Cruz Biotechnology (SCBT) Antibodies for FCRL3
Protein Products
- R&D Systems Proteins and Enzymes for FCRL3 (FCRL3/FcRH3)
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for FCRL3
- Origene Custom Protein Services for FCRL3
- Novus Biologicals proteins for FCRL3
- Search GeneTex for Proteins for FCRL3
-
Abcam proteins for FCRL3
Assay Products
No data available for DME Specific Peptides for FCRL3 Gene
Domains & Families for FCRL3 Gene
Gene Families for FCRL3 Gene
Protein Domains for FCRL3 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for FCRL3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for FCRL3 Gene
Function for FCRL3 Gene
Phenotypes for FCRL3 Gene
- GenomeRNAi human phenotypes for FCRL3:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for FCRL3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FCRL3 gene
- Search ViGene Biosciences for FCRL3
CRISPR Products
-
OriGene CRISPR knockouts for FCRL3
-
Santa Cruz Biotechnology (SCBT) CRISPR for FCRL3
- GenScript: Design CRISPR guide RNA sequences for FCRL3
miRNA Products
- Search ViGene Biosciences for FCRL3
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FCRL3
- Browse OriGene Inhibitory RNA Products For FCRL3
-
ViGene Biosciences ready-to-package AAV shRNAs for FCRL3 gene
Clone Products
-
OriGene ORF clones in human for FCRL3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for FCRL3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- R&D Systems cDNA Clones for FCRL3 (FCRL3/FcRH3)
Cell Line Products
-
Horizon Cell Lines for FCRL3
-
ViGene Biosciences adenoviral particle packaged cDNA for FCRL3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FCRL3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FCRL3 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FCRL3 Gene
Localization for FCRL3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for FCRL3 Gene
- Cell membrane; Single-pass type I membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 1 |
| mitochondrion | 1 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for FCRL3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | B Cell Development Pathways | ||
Pathways by source for FCRL3 Gene
1 R&D Systems pathway for FCRL3 Gene
No data available for SIGNOR curated interactions for FCRL3 Gene
Transcripts for FCRL3 Gene
mRNA/cDNA for FCRL3 Gene
- (4) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (55) Selected AceView cDNA sequences:
- (12) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for FCRL3
-
Santa Cruz Biotechnology (SCBT) CRISPR for FCRL3
- GenScript: Design CRISPR guide RNA sequences for FCRL3
miRNA Products
- Search ViGene Biosciences for FCRL3
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FCRL3
- Browse OriGene Inhibitory RNA Products For FCRL3
-
ViGene Biosciences ready-to-package AAV shRNAs for FCRL3 gene
Clone Products
-
OriGene ORF clones in human for FCRL3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for FCRL3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- R&D Systems cDNA Clones for FCRL3 (FCRL3/FcRH3)
Flow Cytometry Products
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||||||||
| SP3: | - | - | - | ||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||
| SP7: | - | ||||||||||||||||||||||||||||||||
| SP8: |
Expression for FCRL3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Cardiovascular System)
- T Helper Cells Thymus
- Mature B-Cells Peripheral Blood
-
Thymus (Hematopoietic System)
- T Helper Cells Thymus
mRNA differential expression in normal tissues according to GTEx for FCRL3 Gene
This gene is overexpressed in Spleen (x22.0), Whole Blood (x12.0), and Small Intestine - Terminal Ileum (x10.1).
This gene is overexpressed in Plasma (61.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for FCRL3 Gene
NURSA nuclear receptor signaling pathways regulating expression of FCRL3 Gene:
FCRL3SOURCE GeneReport for Unigene cluster for FCRL3 Gene:
Hs.292449mRNA Expression by UniProt/SwissProt for FCRL3 Gene:
Q96P31-FCRL3_HUMAN
Tissue specificity:
Primarily expressed in secondary lymphoid tissues by mature subsets of B-cells. Detected in spleen, lymph node, peripheral blood lymphocytes, thymus, bone marrow, kidney, salivary gland, adrenal gland and uterus. Expressed a low levels in naive, germinal center and memory B-cells but also expressed in NK cells (at protein level).
Evidence on tissue expression from TISSUES for FCRL3 Gene
- Lymph node(4.3)
- Bone marrow(4)
- Thyroid gland(2.5)
Primer Products
-
OriGene qPCR primer pairs for FCRL3
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for FCRL3 Gene
Orthologs for FCRL3 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FCRL3 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | FCRL3 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | FCRL3 34 |
|
||
| -- 35 |
|
ManyToMany | |||
| chicken (Gallus gallus) |
Aves | FCRL2 34 35 |
|
||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | LOC100494132 34 |
|
- Species where no ortholog for FCRL3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for FCRL3 Gene
Paralogs for FCRL3 Gene
(13) SIMAP similar genes for FCRL3 Gene using alignment to 4 proteins:
Variants for FCRL3 Gene
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| VAR_042926 | A breast cancer sample | ||||
| rs1000151000 | -- | 157,697,061(+) | CCACC(A/G)TCCTA | intron-variant | |
| rs1000297160 | -- | 157,677,634(+) | TTACA(C/T)AAGTA | intron-variant, utr-variant-3-prime | |
| rs1000376176 | -- | 157,702,396(+) | CAGCA(C/T)GCTCA | upstream-variant-2KB | |
| rs1000504315 | -- | 157,683,381(+) | CTCCA(C/G)CCTCC | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2761949 | CNV | loss | 21179565 |
| nsv1003791 | CNV | loss | 25217958 |
| nsv520011 | CNV | loss | 19592680 |
| nsv946432 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
92.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.00;
60.21% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FCRL3 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FCRL3 Gene
Disorders for FCRL3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| neuromyelitis optica |
|
|
| rheumatoid arthritis |
|
|
| autoimmune disease of endocrine system |
|
|
| systemic lupus erythematosus |
|
|
| graves' disease |
|
|
Search FCRL3 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
FCRL3_HUMAN- Note=Genetic variation in FCRL3 may influence susceptibility to autoimmune disorders, including Graves disease. Graves disease is an autoimmune disorder associated with overactivity of the thyroid gland and hyperthyroidism. {ECO:0000269 PubMed:15838509, ECO:0000269 PubMed:16384851, ECO:0000269 PubMed:17952073}.
- Rheumatoid arthritis (RA) [MIM:180300]: An inflammatory disease with autoimmune features and a complex genetic component. It primarily affects the joints and is characterized by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. {ECO:0000269 PubMed:15838509, ECO:0000269 PubMed:16176992, ECO:0000269 PubMed:16476711, ECO:0000269 PubMed:16859508, ECO:0000269 PubMed:17133579, ECO:0000269 PubMed:17179172, ECO:0000269 PubMed:17763442}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
Relevant External Links for FCRL3
No data available for Genatlas for FCRL3 Gene
Publications for FCRL3 Gene
- FCRL3 promoter 169 CC homozygosity is associated with susceptibility to rheumatoid arthritis in Dutch Caucasians. (PMID: 17179172) Thabet M.M. … Huizinga T.W.J. (Ann. Rheum. Dis. 2007) 3 4 22 46 64
- Supportive evidence for a genetic association of the FCRL3 promoter polymorphism with rheumatoid arthritis. (PMID: 16176992) Ikari K. … Kamatani N. (Ann. Rheum. Dis. 2006) 3 4 22 46 64
- Epistatic interaction between FCRL3 and NFkappaB1 genes in Spanish patients with rheumatoid arthritis. (PMID: 16476711) Martinez A. … Martin J. (Ann. Rheum. Dis. 2006) 3 4 22 46 64
- Association of the FCRL3 gene with rheumatoid arthritis: a further example of population specificity? (PMID: 16859508) Eyre S. … Barton A. (Arthritis Res. Ther. 2006) 3 4 22 46 64
- Rheumatoid arthritis association with the FCRL3 -169C polymorphism is restricted to PTPN22 1858T-homozygous individuals in a Canadian population. (PMID: 17133579) Newman W.G. … Siminovitch K.A. (Arthritis Rheum. 2006) 3 4 22 46 64
Products for FCRL3 Gene
- R&D Systems Antibodies for FCRL3 (FCRL3/FcRH3)
- R&D Systems Proteins and Enzymes for FCRL3 (FCRL3/FcRH3)
- Browse R&D Systems for biochemical assays
- R&D Systems cDNA Clones for FCRL3 (FCRL3/FcRH3)
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for FCRL3
- Origene Custom Protein Services for FCRL3
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for FCRL3
- Browse OriGene Inhibitory RNA Products For FCRL3
- OriGene qPCR primer pairs for FCRL3
- OriGene CRISPR knockouts for FCRL3
- OriGene ORF clones in human for FCRL3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For FCRL3
- GenScript: Next-day shipping cDNA ORF clone for FCRL3 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for FCRL3
- GenScript Custom Assay Services for FCRL3
- GenScript Custom overexpressing Cell Line Services for FCRL3
- GenScript: Design CRISPR guide RNA sequences for FCRL3
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for FCRL3
- Sino Biological Human cDNA Clone for FCRL3
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for FCRL3
- Novus Biologicals proteins for FCRL3
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for FCRL3
- Abcam proteins for FCRL3
- Search for Assays for FCRL3 at Abcam
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- ViGene Biosciences adenoviral particle packaged cDNA for FCRL3 gene
- ViGene Biosciences lentiviral particle packaged cDNA for FCRL3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for FCRL3 gene
- Search ViGene Biosciences for FCRL3
- Santa Cruz Biotechnology (SCBT) Antibodies for FCRL3
- Search Santa Cruz Biotechnology (SCBT) for FCRL3 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for FCRL3
- Horizon Cell Lines for FCRL3
- Cyagen custom Knockout/knockin (KOKI) mouse models for FCRL3
- VectorBuilder custom plasmid, inducible vectors for FCRL3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FCRL3
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FCRL3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer