FCRL3 Gene
protein-coding GIFtS: 53
GCID: GC01M157646
|
|
Fc receptor-like 3
| |
Aliases for FCRL3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Fc Receptor-Like 31 2 | | SH2 Domain-Containing Phosphatase Anchor Protein 22 3 | | FCRH31 2 3 5 | | SPAP2a1 | | IFGP31 2 3 | | SPAP2b1 | | IRTA31 2 3 | | SPAP2c1 | | SPAP21 2 3 | | SPAP2d1 | | CD307c1 2 | | SPAP2e1 | | FcR-Like Protein 32 3 | | Fc Receptor-Like Protein 32 | | Immune Receptor Translocation-Associated Protein 32 3 | | Immunoglobulin Superfamily Receptor Translocation Associated Protein 32 | | Fc Receptor Homolog 32 3 | | FcRH33 | | HIFGP31 | | FcRL33 | | IFGP Family Protein 32 3 | | CD307c Antigen3 |
Export aliases for FCRL3 gene to outside databasesPrevious GC identifers: GC01M154460 GC01M155912 GC01M129005 |
Summaries for FCRL3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for FCRL3: This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-likeglycoproteins clustered on the long arm of chromosome 1. The encoded protein contains immunoreceptor-tyrosineactivation motifs and immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain and may play a role inregulation of the immune system. Mutations in this gene have been associated with rheumatoid arthritis, autoimmunethyroid disease, and systemic lupus erythematosus. (provided by RefSeq, Jul 2008) Gene Wiki entry for FCRL3
|
Genomic Views for FCRL3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the FCRL3 gene promoter: AML1a Other transcription factors
Search SABiosciences Chromatin IP Primers for FCRL3
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FCRL3 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q21-q22 Ensembl cytogenetic band: 1q23.1 HGNC cytogenetic band: 1q21-q22FCRL3 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M157646: view genomic region
(about GC identifiers)
Start:
|
157,646,271 bp from pter |
End:
|
157,670,775 bp from pter |
Size:
|
24,505 bases |
Orientation:
|
minus strand |
|
Proteins for FCRL3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: FCRL3_HUMAN, Q96P31 (See
protein sequence)Recommended Name: Fc receptor-like protein 3 precursor Size: 734 amino acids; 80856 Da
Subunit: Interacts with PTPN6, PTPN11, SYK and ZAP70
Subcellular location: Cell membrane; Single-pass type I membrane protein
Secondary accessions: A0N0M4 A8MTH7 D3DVD2 Q5VXZ8 Q8N6S2 Q96LA4 Q96P27 Q96P28 Q96P29 Q96P30Alternative splicing: 7 isoforms: Q96P31-1 Q96P31-2 Q96P31-3 Q96P31-4 Q96P31-5 Q96P31-6 Q96P31-7 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for FCRL3: NX_Q96P31
Post-translational modifications:
Phosphorylated on cytoplasmic tyrosines; required for interaction with protein tyrosine phosphatases and proteintyrosine kinases1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96P31 FCRL3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_443171.2 ENSEMBL proteins: ENSP00000433430 ENSP00000435487 ENSP00000357169 ENSP00000434331 ENSP00000357167 ENSP00000292392 Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005886 | plasma membrane |
IEA | -- | | GO:0016021 | integral to membrane |
IEA | -- |
FCRL3 for ontologies About GeneDecksing
FCRL3 Antibody Products: Assay Products for FCRL3: |
Protein
Domains / Families for FCRL3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FCRL3 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q96P31ProtoNet protein and cluster: Q96P31 2 Blocks protein families: IPB002052 N-6 Adenine-specific DNA methylase IPB003598 Immunoglobulin C-2 type
UniProtKB/Swiss-Prot: FCRL3_HUMAN, Q96P31Similarity: Contains 6 Ig-like C2-type (immunoglobulin-like) domains |
Function for FCRL3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FCRL3 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FCRL3 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FCRL3 (NM_052939) | |  | Sino Biological Human cDNA Clone for FCRL3 | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FCRL3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FCRL3  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FCRL3 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004872 | receptor activity |
-- | -- |
FCRL3 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for FCRL3: Animal Models: Mouse knock-out Fcrl5tm1Lex for FCRL3 1 MGI phenotypic allele for Fcrl5 (no phenotypes)
FCRL3 for phenotypes About GeneDecksing
|
Pathways & Interactions for FCRL3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FCRL3
STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)
 4 Interacting proteins for FCRL3 (Q96P313 ENSP000003571674) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds for FCRL3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for FCRL3 Search CenterWatch for drugs/clinical trials and news about FCRL3 
|
Transcripts for FCRL3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for FCRL3 gene (2 alternative transcripts): NM_052939.3 NM_001024667.1 Unigene Cluster for FCRL3: Fc receptor-like 3 Hs.292449 [show with all ESTs]Unigene Representative Sequence: NM_05293912 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000477837 ENST00000492769 ENST00000480682 ENST00000494724 ENST00000368186 ENST00000485028 ENST00000368184(uc001fqx.4 uc001fqy.4 uc001fqz.4 uc009wsn.3 uc009wso.3 uc001frb.3) ENST00000292392(uc001frc.1) ENST00000473231(uc001fra.3) ENST00000468507 ENST00000478179 ENST00000496769
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FCRL3 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FCRL3 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FCRL3 (NM_052939) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FCRL3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FCRL3  |
Additional cDNA sequence: AF459027.1 AK098122.1 AK125622.1 AK301257.1 AY043466.1 BC013698.1 BC028933.1 11 DOTS entries: DT.97839192 DT.99936266 DT.99956633 DT.92325152 DT.100017548 DT.95156352 DT.97839193 DT.97839190 DT.95090097 DT.95156353 DT.97839195 24/55 AceView cDNA sequences (see all 55): AI357107 AA485839 AA485705 BC028933 NM_052939 AK098122 AL833391 AA765694 BM455913 AA972108 AW403530 BM458374 AW576446 BM458414 AF459027 BF514552 BF343316 BG105889 BI836314 BM459359 AF416903 AY043466 AW504347 AK125622 GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for FCRL3 (see all 8) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for FCRL3
|
Expression for FCRL3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FCRL3 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CAGTGCTCTA
About this image See FCRL3 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for FCRL3
SOURCE GeneReport for Unigene cluster: Hs.292449 UniProtKB/Swiss-Prot: FCRL3_HUMAN, Q96P31Tissue specificity: Primarily expressed in secondary lymphoid tissues by mature subsets of B-cells. Detected in spleen,lymph node, peripheral blood lymphocytes, thymus, bone marrow, kidney, salivary gland, adrenal gland and uterus.Expressed a low levels in naive, germinal center and memory B-cells but also expressed in NK cells (at protein level) SABiosciences Custom PCR Arrays for FCRL3
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FCRL3 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FCRL3 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FCRL3 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FCRL3 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FCRL3 |
Orthologs for FCRL3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for FCRL3 gene from 1/8 species (see all 8) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
FCRL21 |
Fc receptor-like 2 |
49.72(n) 39.89(a) |
  |
425592 NM_001097529.1 NP_001090998.1 |
ENSEMBL Gene Tree for FCRL3 (if available) TreeFam Gene Tree for FCRL3 (if available)  |
Paralogs for FCRL3 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for FCRL3 gene
- FCGR2B2 FCGR1B2 FCGR3B2 FCRL22 FCRLB2 FCRL12 FCRL42 FCRL52
- FCRLA2 FCGR1A2 FCGR2A2 FCGR3A2 FCER1A2 FCRL62
11 SIMAP similar genes for FCRL3 using alignment to 3 protein entries: FCRL3_HUMAN (see all proteins):FCRL1 FCRL2 FLJ00333 FCRL4 FCGR3A FCRLB DKFZp686L20250 FCGR2B FCGR1A FCGR3B Fc-gamma receptor IIIB
FCRL3 for paralogs About GeneDecksing
|
Genomic Variants for FCRL3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 1 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for FCRL3 (157646271 - 157670775 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for FCRL3: -- Human Gene Mutation Database (HGMD): FCRL3
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FCRL3 |
|
Disorders
/ Diseases for FCRL3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
FCRL3 for disorders About GeneDecksing
OMIM gene information: 606510
OMIM disorders: --
UniProtKB/Swiss-Prot: FCRL3_HUMAN, Q96P31
Genetic variation in FCRL3 may be a cause of susceptibility to rheumatoid arthritis (RA) [MIM:180300]. It is asystemic inflammatory disease with autoimmune features and a complex genetic component. It primarily affects thejoints and is characterized by inflammatory changes in the synovial membranes and articular structures, widespreadfibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bonystructures Note=Genetic variation in FCRL3 may influence susceptibility to autoimmune disorders, including Gravesdisease. Graves disease is an autoimmune disorder associated with overactivity of the thyroid gland andhyperthyroidism 20/29 diseases for FCRL3 (see all 29): About MalaCardssystemic lupus erythematosus lupus erythematosus rheumatoid arthritis autoimmune thyroiditis arthritis thyroiditis graft versus host disease alopecia areata primary biliary cirrhosis ankylosing spondylitis rheumatoid arthritis, association with chronic lymphocytic leukemia alopecia lymphocytic leukemia spondylitis behcet's disease graves' disease autoimmune pancreatitis autoimmune hepatitis multiple sclerosis
2 diseases from the University of Copenhagen DISEASES database for FCRL3:Rheumatoid arthritis Graves' disease 5 Novoseek disease relationships for FCRL3 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| autoimmune thyroid disease |
74.6 |
5 |
17117947 (1), 17133579 (1), 17462505 (1) |
| autoimmune diseases |
71.8 |
19 |
17200162 (2), 17462505 (2), 17389014 (1), 17868046 (1) (see all 14) |
| rheumatoid arthritis |
62.2 |
16 |
15838509 (2), 16859508 (1), 17117947 (1), 17200162 (1) (see all 11) |
| lupus erythematosus systemic |
55.2 |
7 |
17117947 (1), 18556175 (1), 19690864 (1), 17462505 (1) (see all 5) |
| autoimmunity |
42 |
7 |
17200162 (2), 15838509 (2), 17462505 (2) |
Human Genome Epidemiology (HuGE) Navigator: FCRL3 (38 documents) Export disorders for FCRL3 gene to outside databases
|
Publications for FCRL3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FCRL3 gene, integrated from 9 sources (see all 68): (articles sorted by number of sources associating them with FCRL3) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Identification of a family of Fc receptor homologs with preferential B cell expression. (PubMed id 11493702)1, 2, 3 Davis R.S....Cooper M.D. (2001)
- A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities. (PubMed id 15838509)1, 2, 9 Kochi Y....Yamamoto K. (2005)
- Rheumatoid arthritis association with the FCRL3 -169C polymorphism is restricted to PTPN22 1858T-homozygous individuals in a Canadian population. (PubMed id 17133579)1, 2, 9 Newman W.G.... Siminovitch K.A. (2006)
- FCRL3 promoter 169 CC homozygosity is associated with susceptibility to rheumatoid arthritis in Dutch Caucasians. (PubMed id 17179172)1, 2, 9 Thabet M.M....Huizinga T.W. (2007)
- Epistatic interaction between FCRL3 and NFkappaB1 genes in Spanish patients with rheumatoid arthritis. (PubMed id 16476711)1, 2, 9 Martinez A....Martin J. (2006)
- Association of the FCRL3 gene with rheumatoid arthritis: a further example of population specificity? (PubMed id 16859508)1, 2, 9 Eyre S....Barton A. (2006)
- Supportive evidence for a genetic association of the FCRL3 promoter polymorphism with rheumatoid arthritis. (PubMed id 16176992)1, 2, 9 Ikari K....Kamatani N. (2006)
- Meta-analysis evidence of a differential risk of the FCRL3 -169T-->C polymorphism in white and East Asian rheumatoid arthritis patients. (PubMed id 17763442)1, 2 Begovich A.B.... Schrodi S.J. (2007)
- Contribution of single nucleotide polymorphisms within FCRL3 and MAP3K7IP2 to the pathogenesis of Graves' disease. (PubMed id 16384851)1, 2 Simmonds M.J....Gough S.C.L. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
|
External Searches for FCRL3 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing FCRL3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FCRL3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FCRL3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for FCRL3 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FCRL3 gene: Search GeneIP for patents involving FCRL3
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for FCRL3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for FCRL3 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FCRL3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FCRL3 | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for FCRL3 | | Browse 3'-UTR reporter clones for miRNA target validation | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FCRL3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FCRL3 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for FCRL3 | | OriGene Custom Protein Services for FCRL3 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FCRL3 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FCRL3 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FCRL3 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FCRL3 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FCRL3 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FCRL3 |
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| | | Search Tocris compounds for FCRL3 |
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 | | FCRL3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FCRL3 |
|  |  |  | | | Search ThermoFisher Antibodies for FCRL3 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FCRL3 |
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