Aliases for FCRL2 Gene
External Ids for FCRL2 Gene
Previous HGNC Symbols for FCRL2 Gene
Previous GeneCards Identifiers for FCRL2 Gene
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs. This protein may be a prognostic marker for chronic lymphocytic leukemia. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Apr 2009]
GeneCards Summary for FCRL2 Gene
FCRL2 (Fc Receptor-Like 2) is a Protein Coding gene. Diseases associated with FCRL2 include chronic lymphocytic leukemia. GO annotations related to this gene include SH3/SH2 adaptor activity. An important paralog of this gene is FCRL6.
UniProtKB/Swiss-Prot for FCRL2 Gene
May have an regulatory role in normal and neoplastic B cell development.