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FCRL1 Gene

protein-coding   GIFtS: 50
GCID: GC01M157764

Fc Receptor-Like 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Fc Receptor-Like 11 2     IFGP Family Protein 12 3
FCRH12 3 5     CD307a2
Fc Receptor Homolog 12 3     Fc Receptor-Like Protein 12
FcR-Like Protein 12 3     Immunoglobulin Superfamily Fc Receptor, Gp422
Immune Receptor Translocation-Associated Protein 52 3     FcRH13
IFGP12 3     FcRL13
IRTA52 3     CD307a Antigen3
hIFGP12 3     

External Ids:    HGNC: 185091   Entrez Gene: 1153502   Ensembl: ENSG000001635347   OMIM: 6065085   UniProtKB: Q96LA63   
ORGUL members:         

Export aliases for FCRL1 gene to outside databases

Previous GC identifers: GC01M154579 GC01M156030 GC01M129122


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for FCRL1 Gene:
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like
glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like
immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine
activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing
results in multiple transcript variants. (provided by RefSeq, Apr 2009)

GeneCards Summary for FCRL1 Gene:
FCRL1 (Fc receptor-like 1) is a protein-coding gene. Diseases associated with FCRL1 include hairy cell leukemia, and chronic lymphocytic leukemia. An important paralog of this gene is FCGR1B.

UniProtKB/Swiss-Prot: FCRL1_HUMAN, Q96LA6
Function: May function as an activating coreceptor in B-cells. May function in B-cells activation and
differentiation

Gene Wiki entry for FCRL1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NT_004487.20  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the FCRL1 gene promoter:
         RP58   USF1   AP-1   AML1a   AP-4   Evi-1   RORalpha1   Max   USF-1   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFCRL1 promoter sequence
   Search Chromatin IP Primers for FCRL1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FCRL1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21-q22   Ensembl cytogenetic band:  1q23.1   HGNC cytogenetic band: 1q21-q22

FCRL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FCRL1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M157764:  view genomic region     (about GC identifiers)

Start:
157,764,193 bp from pter      End:
157,789,940 bp from pter
Size:
25,748 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: FCRL1_HUMAN, Q96LA6 (See protein sequence)
Recommended Name: Fc receptor-like protein 1 precursor  
Size: 429 amino acids; 46936 Da
Secondary accessions: B2RE05 Q8N759 Q8NDI0 Q96PJ6
Alternative splicing: 4 isoforms:  Q96LA6-1   Q96LA6-2   Q96LA6-3   Q96LA6-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FCRL1: NX_Q96LA6

Explore proteomics data for FCRL1 at MOPED

Post-translational modifications: 

  • Phosphorylated on tyrosines upon activation1
  • Glycosylation2 at Asn293
  • Modification sites at PhosphoSitePlus

  • See FCRL1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001152869.1  NP_001152870.1  NP_443170.1  

    ENSEMBL proteins: 
     ENSP00000351039   ENSP00000357158   ENSP00000418130  

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    Sino Biological Recombinant Protein for FCRL1
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    Cloud-Clone Corp. Proteins for FCRL1

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    LSBio Antibodies in human, mouse, rat for FCRL1

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    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for FCRL1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for FCRL1
    Cloud-Clone Corp. CLIAs for FCRL1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    CD: CD molecules
    IGD: Immunoglobulin superfamily / Immunoglobulin-like domain containing

    3 InterPro protein domains:
     IPR013783 Ig-like_fold
     IPR007110 Ig-like_dom
     IPR003599 Ig_sub

    Graphical View of Domain Structure for InterPro Entry Q96LA6

    ProtoNet protein and cluster: Q96LA6

    UniProtKB/Swiss-Prot: FCRL1_HUMAN, Q96LA6
    Similarity: Contains 3 Ig-like C2-type (immunoglobulin-like) domains


    FCRL1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FCRL1_HUMAN, Q96LA6
    Function: May function as an activating coreceptor in B-cells. May function in B-cells activation and
    differentiation
    Induction: Down-regulated in activated B-cells

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    FCRL1 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Fcrl1 (no phenotypes)

    FCRL1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Fcrl1tm1Lex for FCRL1

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FCRL1
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FCRL1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FCRL1

    miRNA
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    Block miRNA regulation of human, mouse, rat FCRL1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FCRL1 (see all 10):
    hsa-miR-374b hsa-miR-27a hsa-miR-374a hsa-miR-146a* hsa-miR-9* hsa-miR-3185 hsa-miR-1193 hsa-miR-3919
    SwitchGear 3'UTR luciferase reporter plasmidFCRL1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat FCRL1

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    GenScript: all cDNA clones in your preferred vector (see all 3): FCRL1 (NM_052938)
    Sino Biological Human cDNA Clone for FCRL1
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FCRL1

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FCRL1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    FCRL1_HUMAN, Q96LA6: Cell membrane; Single-pass type I membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    cytosol1
    endoplasmic reticulum1
    extracellular1
    golgi apparatus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0016021integral component of membrane IEA--

    FCRL1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FCRL1
    Interactions:

        Search GeneGlobe Interaction Network for FCRL1

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FCRL1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for FCRL1 gene (3 alternative transcripts): 
    NM_001159397.1  NM_001159398.1  NM_052938.4  

    Unigene Cluster for FCRL1:

    Fc receptor-like 1
    Hs.656112  [show with all ESTs]
    Unigene Representative Sequence: NM_052938
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000463001(uc001frf.3) ENST00000489998 ENST00000358292(uc001frh.3 uc001frg.3 uc001fri.3 uc001frj.3)
    ENST00000368175 ENST00000368176 ENST00000495126 ENST00000491942 ENST00000480310

    miRNA
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    Block miRNA regulation of human, mouse, rat FCRL1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FCRL1 (see all 10):
    hsa-miR-374b hsa-miR-27a hsa-miR-374a hsa-miR-146a* hsa-miR-9* hsa-miR-3185 hsa-miR-1193 hsa-miR-3919
    SwitchGear 3'UTR luciferase reporter plasmidFCRL1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat FCRL1
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): FCRL1 (NM_052938)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FCRL1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FCRL1
    Primer
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    OriGene qPCR primer pairs and template standards for FCRL1
    OriGene qSTAR qPCR primer pairs in human, mouse for FCRL1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FCRL1
      QuantiTect SYBR Green Assays in human, mouse, rat FCRL1
      QuantiFast Probe-based Assays in human, mouse, rat FCRL1

    Additional mRNA sequence: 

    AF329488.1 AF459634.1 AK096690.1 AK315748.1 AL833674.1 AL833970.1 AY043464.1 BC021274.2 
    BC033690.1 

    6 DOTS entries:

    DT.311895  DT.40196801  DT.40201708  DT.100021758  DT.95370220  DT.100721783 

    Selected AceView cDNA sequences (see all 51):

    AL833674 BC033690 AA767265 AK096690 AA810016 CB956381 AA769152 AF459634 
    AY043464 AA813919 NM_052938 AA278822 BC021274 AA766150 AI572979 AA804243 
    AW504600 AA505047 AW198126 AW294948 BP338112 BX644389 AA282433 BX092089 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for FCRL1 (see all 7)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
    SP1:                                -     -                                               -         
    SP2:                                                        -                             -         
    SP3:                                                        -                             -         
    SP4:                                                        -     -                 -               
    SP5:                                                        -     -                       -         


    ECgene alternative splicing isoforms for FCRL1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FCRL1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCACCAAACT
    FCRL1 Expression
    About this image


    FCRL1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             Mature B-Cells Peripheral Blood
     
     Spleen (Hematopoietic System)
    FCRL1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FCRL1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.656112

    UniProtKB/Swiss-Prot: FCRL1_HUMAN, Q96LA6
    Tissue specificity: Primarily expressed in secondary lymphoid tissues by mature subsets of B-cells. Detected in
    spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. Specifically expressed by mature B
    lineage cells with higher expression in naive versus memory B-cells (at protein level)

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for FCRL1 gene from Selected species (see all 5)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fcrl11 , 5 Fc receptor-like 11, 5 75.16(n)1
    59.75(a)1
      3 (38.19 cM)5
    2294991  NM_153090.21  NP_694730.21 
     873763875 
    chicken
    (Gallus gallus)
    Aves FCRL26
    Gallus gallus Fc receptor-like 2 (FCRL2), mRNA.
    21(a)
    1 → many
    25(1587904-1591630)


    ENSEMBL Gene Tree for FCRL1 (if available)
    TreeFam Gene Tree for FCRL1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FCRL1 gene
    FCGR1B2  FCGR2B2  FCRLB2  FCGR3B2  FCRL22  FCRLA2  FCRL52  FCRL42  
    FCGR2A2  FCGR1A2  FCGR3A2  FCRL32  FCER1A2  FCRL62  
    4 SIMAP similar genes for FCRL1 using alignment to 1 protein entry:     FCRL1_HUMAN:
    FCRL2    FCRL3    FCRL5    FLJ00333

    FCRL1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FCRL1 (see all 647)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs772920731,2
    C,F--157763816(+) CATAAT/GGTTCA 3 -- ds50011Minor allele frequency- G:0.03NA 120
    rs1811917921,2
    --157763853(+) AGACTA/GGACAT 3 -- ds50010--------
    rs779373201,2
    F--157763928(+) CAAATG/ACATGC 3 -- ds50011Minor allele frequency- A:0.09WA 118
    rs1843452061,2
    --157763965(+) CATAAA/GATCTA 3 -- ds50010--------
    rs66675561,2
    C,F,A,H--157763970(+) aatctA/Gtgcat 3 -- ds500112Minor allele frequency- G:0.05NS EA NA WA 1486
    rs730171391,2
    C,F--157764143(+) GTGTCC/TGGAGG 3 -- ds50011Minor allele frequency- T:0.50WA 2
    rs1503896851,2
    C--157764200(+) TATAAA/TTTACC 3 -- ut310--------
    rs1890471031,2
    --157764249(+) AGTAAC/TACACC 3 -- ut310--------
    rs569394711,2
    C,F--157764266(+) ACTGAT/CTTCCC 3 -- ut312Minor allele frequency- C:0.05WA 120
    rs759426611,2
    C,F--157764275(+) CCAGAC/TGTTGT 3 -- ut311Minor allele frequency- T:0.05WA 118

    HapMap Linkage Disequilibrium report for FCRL1 (157764193 - 157789940 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for FCRL1: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FCRL1
    DNA2.0 Custom Variant and Variant Library Synthesis for FCRL1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606508    OMIM disorders: --

    10 diseases for FCRL1:    
    About MalaCards
    hairy cell leukemia    chronic lymphocytic leukemia    b-cell chronic lymphocytic leukemia    non-hodgkin lymphoma
    hodgkin's lymphoma    t-cell leukemia    lymphoblastic leukemia    leukemia
    hepatitis b    hepatitis


    FCRL1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): FCRL1
    Human Genome Epidemiology (HuGE) Navigator: FCRL1 (2 documents)

    Export disorders for FCRL1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FCRL1 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with FCRL1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. IRTAs: a new family of immunoglobulin-like receptors differentially expressed in B cells. (PubMed id 11929751)1, 2, 3 Miller I....Dalla-Favera R. (Blood 2002)
    2. Identification of a family of Fc receptor homologs with preferential B cell expression. (PubMed id 11493702)1, 2, 3 Davis R.S.... Cooper M.D. (Proc. Natl. Acad. Sci. U.S.A. 2001)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Expression pattern of the human FcRH/IRTA receptors in normal tissue and in B-chronic lymphocytic leukemia. (PubMed id 16849395)1, 2 Polson A.G.... Ebens A. (Int. Immunol. 2006)
    5. FcRH1: an activation coreceptor on human B cells. (PubMed id 15479727)1, 2 Leu C.-M.... Cooper M.D. (Blood 2005)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. A family of highly diverse human and mouse genes structurally links leukocyte FcR, gp42 and PECAM-1. (PubMed id 12037601)1, 2 Guselnikov S.V.... Taranin A.V. (Immunogenetics 2002)
    8. FCRL1 on chronic lymphocytic leukemia, hairy cell leukemia, and B-cell non-Hodgkin lymphoma as a target of immunotoxins. (PubMed id 17895404)1, 9 Du X....Pastan I. (Blood 2008)
    9. [Expression of human B-cell specific receptor FCRL1 in normal individuals and in patients with autoimmune diseases]. (PubMed id 22888639)1 Baranov K.O....Naiakshin A.M. (Mol. Biol. (Mosk.) 2012)
    10. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (Genes Immun. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 115350 HGNC: 18509 AceView: FCRH1 Ensembl:ENSG00000163534 euGenes: HUgn115350
    ECgene: FCRL1 H-InvDB: FCRL1

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for FCRL1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FCRL1 gene:
    Search GeneIP for patents involving FCRL1

    GeneCards and IP:
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