Aliases for FCN3 Gene
Aliases for FCN3 Gene
External Ids for FCN3 Gene
- HGNC: 3625
- Entrez Gene: 8547
- Ensembl: ENSG00000142748
- OMIM: 604973
- UniProtKB: O75636
Previous GeneCards Identifiers for FCN3 Gene
- GC01P027890
- GC01M026727
- GC01M026928
- GC01M027300
- GC01M027568
- GC01M027695
- GC01M025951
Summaries for FCN3 Gene
-
Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for FCN3 Gene
FCN3 (Ficolin 3) is a Protein Coding gene. Diseases associated with FCN3 include Immunodeficiency Due To Ficolin 3 Deficiency and Progressive Relapsing Multiple Sclerosis. Among its related pathways are Innate Immune System and Creation of C4 and C2 activators. GO annotations related to this gene include carbohydrate binding and antigen binding. An important paralog of this gene is FCN1.
UniProtKB/Swiss-Prot for FCN3 Gene
-
May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FCN3 Gene
Genomics for FCN3 Gene
Regulatory Elements for FCN3 Gene
Enhancers for FCN3 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH01G027368 | 0.9 | Ensembl ENCODE | 0.4 | +5.2 | 5175 | 1.7 | CTCF TAL1 CEBPB DPF2 RAD21 IKZF1 SMC3 ZNF24 RELB IKZF2 | TMEM222 SYTL1 MAP3K6 FCN3 |
| GH01G027382 | 0.7 | Ensembl | 0.4 | -8.6 | -8554 | 1.3 | PKNOX1 KLF1 ZNF146 BCL11B HIC1 POLR2A KDM5B KLF8 PHF8 SP3 | CD164L2 FCN3 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FCN3 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the FCN3 gene promoter:
Regulatory Element Products
Genomic Location for FCN3 Gene
- Chromosome:
- 1
- Start:
- 27,369,110 bp from pter
- End:
- 27,374,825 bp from pter
- Size:
- 5,716 bases
- Orientation:
- Minus strand
Genomic View for FCN3 Gene
Genes around FCN3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p36.11 by Ensembl
- 1p36.11 by Entrez Gene
- 1p36.11 by HGNC
FCN3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FCN3 Gene
Proteins for FCN3 Gene
-
Protein details for FCN3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O75636-FCN3_HUMAN
- Recommended name:
- Ficolin-3
- Protein Accession:
- O75636
- Q6IBJ5
- Q8WW86
Protein attributes for FCN3 Gene
- Size:
- 299 amino acids
- Molecular mass:
- 32903 Da
- Quaternary structure:
-
- Homotrimer (PubMed:17215869). May form an octadecamer consisting of an elementary trimer unit. Does not interact with fibronectin, elastin or zymosan. Interacts with MASP1 and MASP2.
Three dimensional structures from OCA and Proteopedia for FCN3 Gene
Protein Expression for FCN3 Gene
Post-translational modifications for FCN3 Gene
- The N-terminus is blocked.
- Glycosylation at Asn189
- Modification sites at PhosphoSitePlus
Other Protein References for FCN3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
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Abcam antibodies for FCN3
-
Cloud-Clone Corp. Antibodies for FCN3
- Invitrogen Antibodies for FCN3
- antibodies-online Antibodies for FCN3: See all 38
- Search GeneTex for Antibodies for FCN3
Protein Products
- R&D Systems Proteins and Enzymes for FCN3 (Ficolin-3)
-
OriGene Purified Proteins for FCN3
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Cloud-Clone Corp. Proteins for FCN3
- antibodies-online Proteins for FCN3: See all 5
- Search antibodies-online for peptides
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-
Abcam proteins for FCN3
Assay Products
-
Custom Assay ServicesOriGene ELISA Kits for FCN3
-
Cloud-Clone Corp Assay Kits for FCN3
- antibodies-online Kits for FCN3: See all 8
No data available for DME Specific Peptides for FCN3 Gene
Domains & Families for FCN3 Gene
Gene Families for FCN3 Gene
Protein Domains for FCN3 Gene
Suggested Antigen Peptide Sequences for FCN3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O75636- Family:
-
- Belongs to the ficolin lectin family.
Function for FCN3 Gene
Molecular function for FCN3 Gene
- GENATLAS Biochemistry:
- ficolin 3 (collagen/fibrinogen domain-containing),TGF1 binding protein,Hakata antigen,present in the serum as homopolymers,reactin with the serum from patients with systemic lupus erythromatous,expressed in the lung,produced by both ciliated bronchial epithelial cells and Type II alveolar epithelial cells and was secreted into the bronchus and alveolus,also expressed in liver,Hakata antigen is produced by bile duct epithelial cells and hepatocytes and secreted into the bile duct
- UniProtKB/Swiss-Prot Function:
- May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003823 | antigen binding | IDA | 22851708 |
| GO:0004252 | serine-type endopeptidase activity | TAS | -- |
| GO:0005515 | protein binding | IPI | 11907111 |
| GO:0030246 | carbohydrate binding | TAS,IEA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for FCN3 Gene
- GenomeRNAi human phenotypes for FCN3:
Animal Model Products
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ViGene Biosciences lentiviral particle packaged cDNA for FCN3 gene
-
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- Search ViGene Biosciences for FCN3
CRISPR Products
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OriGene CRISPR knockouts for FCN3
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Santa Cruz Biotechnology (SCBT) CRISPR for FCN3
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miRNA Products
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Inhibitory RNA Products
- Origene RNAi, shRNA, and siRNA products in human, mouse, rat for FCN3
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Cell Line Products
-
Horizon Cell Lines for FCN3
-
ViGene Biosciences adenoviral particle packaged cDNA for FCN3 gene
-
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Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FCN3 Gene
Localization for FCN3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for FCN3 Gene
- Secreted. Note=Found in blood plasma, bronchus, alveolus and bile duct.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| plasma membrane | 1 |
| mitochondrion | 1 |
| nucleus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005581 | collagen trimer | IEA | -- |
| GO:0072562 | blood microparticle | IDA | 22516433 |
Pathways & Interactions for FCN3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Creation of C4 and C2 activators | ||
| 2 | Innate Immune System |
.61
|
|
| 3 | Immune response Lectin induced complement pathway | ||
Pathways by source for FCN3 Gene
1 GeneGo (Thomson Reuters) pathway for FCN3 Gene
Interacting Proteins for FCN3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001867 | complement activation, lectin pathway | TAS | -- |
| GO:0002376 | immune system process | IEA | -- |
| GO:0006508 | proteolysis | IEA | -- |
| GO:0006956 | complement activation | TAS | -- |
| GO:0043654 | recognition of apoptotic cell | IDA | 15804047 |
No data available for SIGNOR curated interactions for FCN3 Gene
Transcripts for FCN3 Gene
mRNA/cDNA for FCN3 Gene
- (2) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (81) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FCN3 Gene
CRISPR Products
-
OriGene CRISPR knockouts for FCN3
-
Santa Cruz Biotechnology (SCBT) CRISPR for FCN3
- GenScript: Design CRISPR guide RNA sequences for FCN3
miRNA Products
- Search ViGene Biosciences for FCN3
Inhibitory RNA Products
- Origene RNAi, shRNA, and siRNA products in human, mouse, rat for FCN3
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-
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Clone Products
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Flow Cytometry Products
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||
| SP3: | |||||||||||||||||||||
| SP4: |
Expression for FCN3 Gene
mRNA differential expression in normal tissues according to GTEx for FCN3 Gene
This gene is overexpressed in Lung (x26.4) and Liver (x6.5).
This gene is overexpressed in Serum (35.7), Plasma (20.6), and Synovial fluid (8.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for FCN3 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of FCN3 Gene:
FCN3SOURCE GeneReport for Unigene cluster for FCN3 Gene:
Hs.333383mRNA Expression by UniProt/SwissProt for FCN3 Gene:
O75636-FCN3_HUMAN
Tissue specificity:
Liver and lung. In liver it is produced by bile duct epithelial cells and hepatocytes. In lung it is produced by both ciliated bronchial epithelial cells and type II alveolar epithelial cells.
Evidence on tissue expression from TISSUES for FCN3 Gene
- Liver(4.5)
- Lung(4.5)
- Bone marrow(4)
- Blood(2)
Phenotype-based relationships between genes and organs from Gene ORGANizer for FCN3 Gene
Germ Layers:
- ectoderm
- mesoderm
Systems:
- immune
- integumentary
- lymphatic
- respiratory
Organs:
Thorax:
- bronchus
- lung
Limb:
- digit
- foot
- lower limb
- toe
General:
- blood
- bone marrow
- skin
- white blood cell
Primer Products
-
OriGene qPCR primer pairs for FCN3
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for FCN3 Gene
Orthologs for FCN3 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FCN3 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | FCN3 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
ManyToMany | |
| mouse (Mus musculus) |
Mammalia | Fcna 35 |
|
ManyToMany | |
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
ManyToMany | |
| fruit fly (Drosophila melanogaster) |
Insecta | CG30280 36 |
|
|
|
| CG30281 36 |
|
|
|||
| CG5550 36 |
|
|
|||
| sca 36 |
|
|
|||
| CG41520 35 |
|
OneToMany | |||
| worm (Caenorhabditis elegans) |
Secernentea | T15B7.1 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
ManyToMany | |
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany |
- Species where no ortholog for FCN3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- dog (Canis familiaris)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- zebrafish (Danio rerio)
Paralogs for FCN3 Gene
Paralogs for FCN3 Gene
(27) SIMAP similar genes for FCN3 Gene using alignment to 3 proteins:
Variants for FCN3 Gene
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs532781899 | Pathogenic | 27,373,180(+) | GGAGG(-/G)CCCTG | reference, frameshift-variant | |
| rs1000151649 | -- | 27,372,761(+) | ATGCC(C/T)CTCCC | intron-variant | |
| rs1001720221 | -- | 27,371,951(+) | AGATG(C/G)GGTTT | intron-variant | |
| rs1001864708 | -- | 27,376,272(+) | GACCT(C/T)AGGTG | upstream-variant-2KB | |
| rs1002052355 | -- | 27,370,625(+) | CCAGT(A/G)CCAGC | reference, missense |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv1006916 | CNV | deletion | 20482838 |
| nsv1147132 | CNV | insertion | 26484159 |
| nsv516766 | CNV | loss | 19592680 |
| nsv526051 | CNV | gain | 19592680 |
Residual Variation Intolerance Score:
90.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.02;
50.08% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FCN3 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FCN3 Gene
Disorders for FCN3 Gene
(5) MalaCards diseases for FCN3 Gene - From: OMIM, ClinVar, GeneTests, Orphanet, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| immunodeficiency due to ficolin 3 deficiency |
|
|
| progressive relapsing multiple sclerosis |
|
|
| rheumatic fever |
|
|
| hereditary angioedema |
|
|
| systemic lupus erythematosus |
|
|
Search FCN3 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
FCN3_HUMAN- Ficolin 3 deficiency (FCN3D) [MIM:613860]: A disorder characterized by immunodeficiency, recurrent infections, brain abscesses and recurrent warts on the fingers. Affected individuals have normal levels of lymphocytes, normal T-cell responses, and normal antibodies, but a selective deficient antibody response to pneumococcal polysaccharide vaccine. {ECO:0000269 PubMed:19535802}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Relevant External Links for FCN3
No data available for Genatlas for FCN3 Gene
Publications for FCN3 Gene
- Exploring the role of polymorphisms in ficolin genes in respiratory tract infections in children. (PMID: 19220833) Ruskamp J.M. … Sanders E.A. (Clin. Exp. Immunol. 2009) 3 22 46 64
- Structural insights into the innate immune recognition specificities of L- and H-ficolins. (PMID: 17215869) Garlatti V. … Gaboriaud C. (EMBO J. 2007) 3 4 22 64
- Polymorphisms in the ficolin 1 gene (FCN1) are associated with susceptibility to the development of rheumatoid arthritis. (PMID: 18032536) Vander Cruyssen B. … De Keyser F. (Rheumatology (Oxford) 2007) 3 22 46 64
- Activation of the lectin complement pathway by H-ficolin (Hakata antigen). (PMID: 11907111) Matsushita M. … Fujita T. (J. Immunol. 2002) 3 4 22 64
- Hakata antigen, a new member of the ficolin/opsonin p35 family, is a novel human lectin secreted into bronchus/alveolus and bile. (PMID: 10330454) Akaiwa M. … Hamasaki N. (J. Histochem. Cytochem. 1999) 2 3 4 64
Products for FCN3 Gene
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- antibodies-online Antibodies for FCN3: See all 38
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- antibodies-online Proteins for FCN3: See all 5
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- ViGene Biosciences adenoviral particle packaged cDNA for FCN3 gene
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- Horizon Cell Lines for FCN3
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- VectorBuilder custom plasmid, inducible vectors for FCN3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FCN3
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FCN3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer