Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



FCHSD2 Gene

protein-coding   GIFtS: 49
GCID: GC11M072547

FCH And Double SH3 Domains 2

(Previous name: SH3 multiple domains 3)
(Previous symbol: SH3MD3)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
FCH And Double SH3 Domains 21 2     carom2
SH3MD31 2 3     FCH And Double SH3 Domains Protein 22
SH3 Multiple Domains 31 2     Nervous Wreck Homolog2
SH3 Multiple Domains Protein 32 3     Carom3
NWK2     KIAA07693

External Ids:    HGNC: 291141   Entrez Gene: 98732   Ensembl: ENSG000001374787   UniProtKB: O948683   

Export aliases for FCHSD2 gene to outside databases

Previous GC identifers: GC11M072275 GC11M072225 GC11M068842


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for FCHSD2 Gene:
FCHSD2 (FCH and double SH3 domains 2) is a protein-coding gene. Diseases associated with FCHSD2 include genital herpes, and pulmonary edema. An important paralog of this gene is FCHSD1.

Gene Wiki entry for FCHSD2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
Regulatory elements:
   Regulatory transcription factor binding sites in the FCHSD2 gene promoter:
         TBP   STAT1   NF-1/L   NF-1   Sp1   HNF-3beta   Egr-4   Gfi-1   AREB6   TFIID   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFCHSD2 promoter sequence
   Search Chromatin IP Primers for FCHSD2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FCHSD2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13.4   Ensembl cytogenetic band:  11q13.4   HGNC cytogenetic band: 11q13.3

FCHSD2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FCHSD2 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M072547:  view genomic region     (about GC identifiers)

Start:
72,547,790 bp from pter      End:
72,853,306 bp from pter
Size:
305,517 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: FCSD2_HUMAN, O94868 (See protein sequence)
Recommended Name: FCH and double SH3 domains protein 2  
Size: 740 amino acids; 84276 Da
Subunit: Interacts with CASK and MAGI1. CASK inhibits interaction with MAGI1
Sequence caution: Sequence=BAA34489.2; Type=Erroneous initiation;
2 PDB 3D structures from and Proteopedia for FCHSD2:
2DL5 (3D)        2DL7 (3D)    
Secondary accessions: B4DNI3 Q7L8J9 Q8WVM2 Q96FV7 Q9UF77
Alternative splicing: 3 isoforms:  O94868-1   O94868-2   O94868-3   

Explore the universe of human proteins at neXtProt for FCHSD2: NX_O94868

Explore proteomics data for FCHSD2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See FCHSD2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055639.2  
    ENSEMBL proteins: 
     ENSP00000308978   ENSP00000386987   ENSP00000386722   ENSP00000386903   ENSP00000402972  
     ENSP00000386314   ENSP00000406420   ENSP00000441616   ENSP00000408706  

    FCHSD2 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for FCHSD2
    OriGene Protein Over-expression Lysate for FCHSD2
    OriGene MassSpec for FCHSD2
    OriGene Custom Protein Services for FCHSD2
    GenScript Custom Purified and Recombinant Proteins Services for FCHSD2
    Novus Biologicals FCHSD2 Protein
    Novus Biologicals FCHSD2 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for FCHSD2

    FCHSD2 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for FCHSD2
    OriGene Custom Antibody Services for FCHSD2
    Novus Biologicals FCHSD2 Antibody
    Abcam antibodies for FCHSD2 (O94868, O94868 )
    Cloud-Clone Corp. Antibodies for FCHSD2
    Search ThermoFisher Antibodies for FCHSD2
    LSBio Antibodies in human, mouse, rat for FCHSD2

    FCHSD2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for FCHSD2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for FCHSD2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for FCHSD2
    Cloud-Clone Corp. CLIAs for FCHSD2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    2 InterPro protein domains:
     IPR001060 FCH_dom
     IPR001452 SH3_domain

    Graphical View of Domain Structure for InterPro Entry O94868

    ProtoNet protein and cluster: O94868

    1 Blocks protein domain: IPB001452 SH3 domain signature

    UniProtKB/Swiss-Prot: FCSD2_HUMAN, O94868
    Similarity: Contains 1 FCH domain
    Similarity: Contains 2 SH3 domains


    FCHSD2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI14627983
         
    FCHSD2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FCHSD2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FCHSD2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FCHSD2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FCHSD2

    miRNA
    Products:
        
    miRTarBase miRNAs that target FCHSD2:
    hsa-mir-124-3p (MIRT023044)

    Block miRNA regulation of human, mouse, rat FCHSD2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FCHSD2 (see all 47):
    hsa-miR-576-3p hsa-miR-3194-5p hsa-miR-4272 hsa-miR-15a hsa-miR-503 hsa-miR-605 hsa-miR-3653 hsa-miR-219-5p
    SwitchGear 3'UTR luciferase reporter plasmidFCHSD2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for FCHSD2
    Predesigned siRNA for gene silencing in human, mouse, rat FCHSD2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for FCHSD2

    Clone
    Products:
         
    OriGene clones in human, mouse for FCHSD2 (see all 11)
    OriGene ORF clones in mouse, rat for FCHSD2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FCHSD2 (NM_014824)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FCHSD2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FCHSD2

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for FCHSD2
    Browse ESI BIO Cell Lines and PureStem Progenitors for FCHSD2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FCHSD2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2
    cytoskeleton1
    plasma membrane1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FCHSD2
    Interactions:

        Search GeneGlobe Interaction Network for FCHSD2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for FCHSD2 (O948681, 2, 3 ENSP000003867224) via UniProtKB, MINT, STRING, and/or I2D (see all 71)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    VCPP550721, 3, ENSP000003517774EBI-1215612,EBI-355164 I2D: score=1 STRING: ENSP00000351777
    MAGI1Q96QZ71, 3, ENSP000003854504EBI-1215612,EBI-924464 I2D: score=2 STRING: ENSP00000385450
    CCDC85BQ158343, ENSP000003116954I2D: score=4 STRING: ENSP00000311695
    CASKO149363, ENSP000003674084I2D: score=3 STRING: ENSP00000367408
    C2orf73Q8N5S33, ENSP000003816314I2D: score=1 STRING: ENSP00000381631
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FCHSD2 (FCSD2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for FCHSD2 gene: 
    NM_014824.2  

    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000311172(uc001oth.4) ENST00000409314(uc009ytl.3 uc010rrg.2)
    ENST00000409418 ENST00000409263 ENST00000458644 ENST00000409853(uc001oti.2)
    ENST00000432043 ENST00000543644 ENST00000422375
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat FCHSD2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FCHSD2 (see all 47):
    hsa-miR-576-3p hsa-miR-3194-5p hsa-miR-4272 hsa-miR-15a hsa-miR-503 hsa-miR-605 hsa-miR-3653 hsa-miR-219-5p
    SwitchGear 3'UTR luciferase reporter plasmidFCHSD2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for FCHSD2
    Predesigned siRNA for gene silencing in human, mouse, rat FCHSD2
    Clone
    Products:
         
    OriGene clones in human, mouse for FCHSD2 (see all 11)
    OriGene ORF clones in mouse, rat for FCHSD2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FCHSD2 (NM_014824)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FCHSD2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FCHSD2
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for FCHSD2
    OriGene qSTAR qPCR primer pairs in human, mouse for FCHSD2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FCHSD2
      QuantiTect SYBR Green Assays in human, mouse, rat FCHSD2
      QuantiFast Probe-based Assays in human, mouse, rat FCHSD2

    Selected AceView cDNA sequences (see all 167):

    AI866699 AI201270 AI243845 AA768713 AW504155 BU625889 BU615534 AI985360 
    BM842025 BX643249 BQ018424 BQ021044 BQ181350 BQ007622 BG541971 AA831767 
    AL046367 AI825771 BU621921 AI655690 AI623254 AI672421 BQ720875 BE463795 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    FCHSD2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCTCCTTTTT
    FCHSD2 Expression
    About this image

    FCHSD2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FCHSD2 Protein Expression

    UniProtKB/Swiss-Prot: FCSD2_HUMAN, O94868
    Tissue specificity: Liver, brain, heart, placenta, skeletal muscle, pancreas, lung and kidney

        Custom PCR Arrays for FCHSD2
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for FCHSD2
    OriGene qSTAR qPCR primer pairs in human, mouse for FCHSD2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FCHSD2
    QuantiTect SYBR Green Assays in human, mouse, rat FCHSD2
    QuantiFast Probe-based Assays in human, mouse, rat FCHSD2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FCHSD2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for FCHSD2 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fchsd21 , 5 FCH and double SH3 domains 21, 5 91.8(n)1
    96.49(a)1
      7 (54.50 cM)5
    2072781  NM_199012.21  NP_950177.21 
     1011087755 
    chicken
    (Gallus gallus)
    Aves FCHSD21 FCH and double SH3 domains 2 80.48(n)
    88.18(a)
      419068  XM_417258.4  XP_417258.4 
    lizard
    (Anolis carolinensis)
    Reptilia FCHSD26
    FCH and double SH3 domains 2
    88(a)
    1 ↔ 1
    GL343298.1(502074-683197)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia BX688645.12   -- 73.29(n)    BX688645.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BI881946.12   -- 74.15(n)    BI881946.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta nwk1 nervous wreck 49.24(n)
    41.46(a)
      39052  NM_001259763.2  NP_001246692.1 


    ENSEMBL Gene Tree for FCHSD2 (if available)
    TreeFam Gene Tree for FCHSD2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for FCHSD2 gene
    FCHSD12  
    4 SIMAP similar genes for FCHSD2 using alignment to 7 protein entries:     FCSD2_HUMAN (see all proteins):
    ARHGEF7    FCHSD1    SH3GL1    SH3GL2

    FCHSD2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for FCHSD2 (see all 4869)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs760226791,2
    C--68923110(+) CATTC-/TTTTTTTT
    TTTTTTTTTT
    TTTTT
    1 -- int10--------
    rs3740801341,2
    C--68960208(+) GGGGA-/A/    
       T
    /TTT
    TTTTT
    1 -- int10--------
    rs1180519171,2
    C,F--72410935(+) GGGACC/TGAGAA 1 -- int11Minor allele frequency- T:0.02NA 120
    rs1153139981,2
    F--72410965(+) CATTAC/TTCCTT 1 -- int11Minor allele frequency- T:0.05WA 118
    rs729698211,2
    C,F--72411108(+) AGCTGC/ACTCTA 1 -- int11Minor allele frequency- A:0.02WA 118
    rs560600521,2
    --72411177(+) TTTTTG/TCCCAT 1 -- int10--------
    rs1440013661,2
    C--72411177(+) TTTTT-/CCCCAT 1 -- int10--------
    rs1402649801,2
    C--72411192(+) AAAGCA/GAAGAC 1 -- int10--------
    rs10453721,2
    C--72411533(-) GCACCA/CCAGTG 1 -- ut31 ese33Minor allele frequency- C:0.00MN NA 188
    rs746695411,2
    C,F--72411760(+) ATTTAA/GTAAGC 1 -- ut312Minor allele frequency- G:0.07NA EA 240

    HapMap Linkage Disequilibrium report for FCHSD2 (72547790 - 72797790 bp, first 250kb of FCHSD2)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for FCHSD2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2422418CNV Duplication17116639
    nsv386CNV Loss18451855

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FCHSD2
    DNA2.0 Custom Variant and Variant Library Synthesis for FCHSD2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    10 diseases for FCHSD2:    
    About MalaCards
    genital herpes    pulmonary edema    crohn's disease    acute myeloid leukemia
    myeloid leukemia    pancreatic cancer    pancreatitis    leukemia
    malaria    neuronitis


    FCHSD2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): FCHSD2
    Human Genome Epidemiology (HuGE) Navigator: FCHSD2 (1 document)

    Export disorders for FCHSD2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for FCHSD2 gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with FCHSD2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of human FCHSD1 and FCHSD2 genes in silico. (PubMed id 15067381)1, 2, 3, 9 Katoh M. and Katoh M. (Int. J. Mol. Med. 2004)
    2. Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9872452)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 1998)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)1, 2 Taylor T.D....Sakaki Y. (Nature 2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Carom: a novel membrane-associated guanylate kinase-interacting protein with two SH3 domains. (PubMed id 14627983)1, 2 Ohno H.... Hata Y. (Oncogene 2003)
    7. Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations. (PubMed id 23850713)1 Yang S.K....Song K. (Gut 2014)
    8. A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population. (PubMed id 23266558)1 Yamazaki K....Kubo M. (Gastroenterology 2013)
    9. FCHSD2 predicts response to chemotherapy in acute myeloid leukemia patients. (PubMed id 22902056)1 Han Y....Minden M.D. (Leuk. Res. 2012)
    10. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (J. Cell. Sci. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 9873 HGNC: 29114 AceView: FCHSD2 Ensembl:ENSG00000137478 euGenes: HUgn9873
    ECgene: FCHSD2 H-InvDB: FCHSD2

    (According to HUGE)
    About This Section

    TryGeneCards Plus
    HUGE: KIAA0769

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for FCHSD2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for FCHSD2 gene:
    Search GeneIP for patents involving FCHSD2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for FCHSD2   OriGene RNAi products in human, mouse, rat for FCHSD2  
     OriGene qPCR primer pairs and template standards for FCHSD2   OriGene Protein Over-expression Lysate for FCHSD2  
     OriGene MassSpec something-or-other for FCHSD2   OriGene clones in human, mouse for FCHSD2  
     OriGene qSTAR qPCR primer pairs in human, mouse for FCHSD2   OriGene Purified Protein for FCHSD2  
     OriGene ORF clones in mouse, rat for FCHSD2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for FCHSD2   OriGene Custom Protein Services for FCHSD2  

     
     
     Block miRNA regulation of human, mouse, rat FCHSD2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing FCHSD2
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FCHSD2 Predesigned siRNA for gene silencing in human, mouse, rat FCHSD2
     QuantiFast Probe-based Assays in human, mouse, rat FCHSD2 QuantiTect SYBR Green Assays in human, mouse, rat FCHSD2
     Custom PCR Arrays for FCHSD2 Search Chromatin IP Primers for FCHSD2
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FCHSD2  Search GeneGlobe Interaction Network for FCHSD2
     Regulatory tfbs in FCHSD2 promoter
     GenScript Custom Purified and Recombinant Proteins Services for FCHSD2 GenScript cDNA clones with any tag delivered in your preferred vector for FCHSD2
     GenScript Custom Assay Services for FCHSD2 GenScript Custom overexpressing Cell Line Services for FCHSD2
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for FCHSD2 (FCSD2)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     FCHSD2 antibodies
     FCHSD2 proteins
     FCHSD2 lysates
     Antibodies for FCHSD2
     See all of Abcam's Antibodies, Kits and Proteins for FCHSD2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for FCHSD2
     Antibodies for FCHSD2
     ELISAs for FCHSD2
     CLIAs for FCHSD2



     Browse ESI BIO Cell Lines and PureStem Progenitors for FCHSD2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FCHSD2
     SwitchGear 3'UTR luciferase reporter plasmids for FCHSD2
     SwitchGear Promoter luciferase reporter plasmids for FCHSD2
     Search ThermoFisher Antibodies for FCHSD2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FCHSD2
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FCHSD2
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FCHSD2
     LSBio Antibodies in human, mouse, rat for FCHSD2
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      FCHSD2 gene at Home site.
    Version: 3.12.162 20 Aug 2014
    hostname: 356980-web2.xennexinc.com index build: 126 solr: 1.4