Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



FCHSD1 Gene

protein-coding   GIFtS: 51
GCID: GC05M141018

FCH And Double SH3 Domains 1

  Search for FCHSD1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
FCH And Double SH3 Domains 11 2
NWK22
FCH And Double SH3 Domains Protein 12
Nervous Wreck Homolog 22

External Ids:    HGNC: 254631   Entrez Gene: 898482   Ensembl: ENSG000001979487   UniProtKB: Q86WN13   

Export aliases for FCHSD1 gene to outside databases

Previous GC identifers: GC05M141048 GC05M140999 GC05M136163


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for FCHSD1 Gene:
FCHSD1 (FCH and double SH3 domains 1) is a protein-coding gene. An important paralog of this gene is FCHSD2.

Gene Wiki entry for FCHSD1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000005.10  NT_029289.12  NC_018916.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the FCHSD1 gene promoter:
         AP-2alpha isoform 3   AP-1   AP-2alpha isoform 2   AP-2alpha isoform 4   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFCHSD1 promoter sequence
   Search Chromatin IP Primers for FCHSD1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FCHSD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q31.3   Ensembl cytogenetic band:  5q31.3   HGNC cytogenetic band: 5q31.3

FCHSD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FCHSD1 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M141018:  view genomic region     (about GC identifiers)

Start:
141,018,869 bp from pter      End:
141,030,986 bp from pter
Size:
12,118 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: FCSD1_HUMAN, Q86WN1 (See protein sequence)
Recommended Name: FCH and double SH3 domains protein 1  
Size: 690 amino acids; 76942 Da
Sequence caution: Sequence=BAA92232.1; Type=Erroneous initiation;
Secondary accessions: Q6UX75 Q86Y77 Q9NXX8
Alternative splicing: 3 isoforms:  Q86WN1-1   Q86WN1-2   Q86WN1-3   

Explore the universe of human proteins at neXtProt for FCHSD1: NX_Q86WN1

Explore proteomics data for FCHSD1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See FCHSD1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_258260.1  
    ENSEMBL proteins: 
     ENSP00000399259   ENSP00000427796   ENSP00000428677   ENSP00000430448   ENSP00000428776  

    FCHSD1 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for FCHSD1
    OriGene Protein Over-expression Lysate for FCHSD1
    OriGene Custom MassSpec
    OriGene Custom Protein Services for FCHSD1
    GenScript Custom Purified and Recombinant Proteins Services for FCHSD1
    Novus Biologicals FCHSD1 Protein
    Novus Biologicals FCHSD1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for FCHSD1

    FCHSD1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for FCHSD1
    OriGene Custom Antibody Services for FCHSD1
    Novus Biologicals FCHSD1 Antibodies
    Abcam antibodies for FCHSD1
    Cloud-Clone Corp. Antibodies for FCHSD1
    Search ThermoFisher Antibodies for FCHSD1
    LSBio Antibodies in human, mouse, rat for FCHSD1

    FCHSD1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for FCHSD1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for FCHSD1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for FCHSD1
    Cloud-Clone Corp. CLIAs for FCHSD1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    2 InterPro protein domains:
     IPR001060 FCH_dom
     IPR001452 SH3_domain

    Graphical View of Domain Structure for InterPro Entry Q86WN1

    ProtoNet protein and cluster: Q86WN1

    3 Blocks protein domains:
    IPB001060 Cdc15/Fes/CIP4
    IPB001452 SH3 domain signature
    IPB011511 Variant SH3


    UniProtKB/Swiss-Prot: FCSD1_HUMAN, Q86WN1
    Similarity: Contains 1 FCH domain
    Similarity: Contains 2 SH3 domains


    FCHSD1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    FCHSD1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for FCHSD1:
     Decreased Wnt reporter activit 

         1 MGI phenotypic allele for Fchsd1 (no phenotypes)

    FCHSD1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Fchsd1tm1Lex for FCHSD1

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FCHSD1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FCHSD1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FCHSD1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FCHSD1

    miRNA
    Products:
        
    miRTarBase miRNAs that target FCHSD1:
    hsa-mir-335-5p (MIRT018693)

    Block miRNA regulation of human, mouse, rat FCHSD1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FCHSD1 (see all 34):
    hsa-miR-4254 hsa-miR-15a hsa-miR-29a hsa-miR-766 hsa-miR-4267 hsa-miR-424 hsa-miR-637 hsa-miR-654-5p
    SwitchGear 3'UTR luciferase reporter plasmidFCHSD1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for FCHSD1
    Predesigned siRNA for gene silencing in human, mouse, rat FCHSD1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for FCHSD1

    Clone
    Products:
         
    OriGene clones in human, mouse for FCHSD1 (see all 7)
    OriGene ORF clones in mouse, rat for FCHSD1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FCHSD1 (NM_033449)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FCHSD1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FCHSD1

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for FCHSD1
    Browse ESI BIO Cell Lines and PureStem Progenitors for FCHSD1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FCHSD1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    mitochondrion2
    nucleus2
    peroxisome1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FCHSD1
    Interactions:

        Search GeneGlobe Interaction Network for FCHSD1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for FCHSD1 (Q86WN12, 3 ENSP000003992594) via UniProtKB, MINT, STRING, and/or I2D (see all 54)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HSPA1AP081073, ENSP000003648024I2D: score=1 STRING: ENSP00000364802
    ENSG00000212866P081073I2D: score=1 
    ENSG00000215328P081073I2D: score=1 
    ENSG00000224501P081073I2D: score=1 
    ENSG00000231555P081073I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FCHSD1 (FCSD1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for FCHSD1 gene: 
    NM_033449.2  

    Unigene Cluster for FCHSD1:

    FCH and double SH3 domains 1
    Hs.591257  [show with all ESTs]
    Unigene Representative Sequence: AY217346
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000435817(uc003llj.3 uc003llk.3) ENST00000520747 ENST00000523856(uc010jgg.3)
    ENST00000522126 ENST00000522783 ENST00000518160 ENST00000518499 ENST00000522763
    ENST00000522386 ENST00000519800
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat FCHSD1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FCHSD1 (see all 34):
    hsa-miR-4254 hsa-miR-15a hsa-miR-29a hsa-miR-766 hsa-miR-4267 hsa-miR-424 hsa-miR-637 hsa-miR-654-5p
    SwitchGear 3'UTR luciferase reporter plasmidFCHSD1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for FCHSD1
    Predesigned siRNA for gene silencing in human, mouse, rat FCHSD1
    Clone
    Products:
         
    OriGene clones in human, mouse for FCHSD1 (see all 7)
    OriGene ORF clones in mouse, rat for FCHSD1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FCHSD1 (NM_033449)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FCHSD1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FCHSD1
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for FCHSD1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FCHSD1
      QuantiTect SYBR Green Assays in human, mouse, rat FCHSD1
      QuantiFast Probe-based Assays in human, mouse, rat FCHSD1

    Additional mRNA sequence: 

    AF086518.1 AK000007.1 AY217346.1 

    12 DOTS entries:

    DT.409936  DT.95076258  DT.92390191  DT.120855897  DT.100796558  DT.120855920  DT.102829288  DT.120855924 
    DT.92426748  DT.40201200  DT.97765190  DT.97855127 

    Selected AceView cDNA sequences (see all 89):

    AI382649 CD364643 BE272762 BM449936 AF086518 BC047016 BM825872 BU849451 
    AK000007 BU074147 NM_033449 AY217346 BM666027 AK126203 BM193837 AI204381 
    AI417105 AI865011 BE242637 AW337193 BM710927 AI858504 BE410602 AW052085 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for FCHSD1 (see all 12)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b · 11c ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15a · 15b · 15c ^
    SP1:        -                                                     -     -                                                                                       
    SP2:        -                 -                                   -     -                                                                                       
    SP3:        -                                                                                                                                                   
    SP4:                                                                                                              -                                             
    SP5:                                                                                                                                                            

    ExUns: 16a · 16b ^ 17 ^ 18 ^ 19a · 19b ^ 20a · 20b ^ 21a · 21b · 21c
    SP1:                                                                  
    SP2:                                                                  
    SP3:                                                                  
    SP4:                                                                  
    SP5:                          -     -     -                           


    ECgene alternative splicing isoforms for FCHSD1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    FCHSD1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACCCACCCCA
    FCHSD1 Expression
    About this image

    FCHSD1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FCHSD1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.591257
        Custom PCR Arrays for FCHSD1
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for FCHSD1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FCHSD1
    QuantiTect SYBR Green Assays in human, mouse, rat FCHSD1
    QuantiFast Probe-based Assays in human, mouse, rat FCHSD1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FCHSD1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for FCHSD1 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fchsd11 , 5 FCH and double SH3 domains 11, 5 88.13(n)1
    91.28(a)1
      18 (19.84 cM)5
    3192621  NM_175684.41  NP_783615.21 
     379574315 
    chicken
    (Gallus gallus)
    Aves FCHSD11 FCH and double SH3 domains 1 61.44(n)
    50.62(a)
      427616  XM_425188.4  XP_425188.4 
    lizard
    (Anolis carolinensis)
    Reptilia FCHSD16
    FCH and double SH3 domains 1
    45(a)
    1 ↔ 1
    4(76238088-76285662)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia fchsd11 FCH and double SH3 domains 1 58.16(n)
    52.5(a)
      100489010  XM_002939991.2  XP_002940037.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta nwk6
    nervous wreck
    17(a)
    1 → many
    3L(9130960-9138793)


    ENSEMBL Gene Tree for FCHSD1 (if available)
    TreeFam Gene Tree for FCHSD1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for FCHSD1 gene
    FCHSD22  
    1 SIMAP similar gene for FCHSD1 using alignment to 4 protein entries:     FCSD1_HUMAN (see all proteins):
    FCHSD2

    FCHSD1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for FCHSD1 (see all 346)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2010116971,2
    C--141021238(+) TCTACA/GTACAA 1 -- int10--------
    rs1817185741,2
    --141021273(+) CCGGCC/TTGAGT 2 K R mis10--------
    rs1167721381,2
    C,F--141021294(+) TCATGT/GCCAGG 2 /D /A mis12Minor allele frequency- G:0.03NA EU 713
    rs1862307561,2
    --141021360(+) GACTTC/TGTTTT 1 -- int10--------
    rs1910338601,2
    --141021414(+) AAATAG/TTTGTT 1 -- int10--------
    rs1821355211,2
    --141021462(+) ACTCTA/GTCCAC 1 -- int10--------
    rs1398253111,2
    C--141021542(+) GGATGC/TATAGT 1 -- int10--------
    rs1453508601,2
    --141021590(+) AAACCC/TCAACA 1 -- int10--------
    rs65801931,2
    C,F,A--141021716(+) TAGAAA/TAGGCA 1 -- int11Minor allele frequency- T:0.12WA 118
    rs1506407451,2
    --141021848(+) ACTTAC/TAAGTG 1 -- int10--------

    HapMap Linkage Disequilibrium report for FCHSD1 (141018869 - 141030986 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for FCHSD1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv5034CNV Insertion18451855

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FCHSD1
    DNA2.0 Custom Variant and Variant Library Synthesis for FCHSD1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus

    FCHSD1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): FCHSD1
    Human Genome Epidemiology (HuGE) Navigator: FCHSD1 (4 documents)

    Export disorders for FCHSD1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for FCHSD1 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with FCHSD1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of human FCHSD1 and FCHSD2 genes in silico. (PubMed id 15067381)1, 2, 3, 9 Katoh M. and Katoh M. (Int. J. Mol. Med. 2004)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    4. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W.... Wilson R.K. (Nature 2005)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    8. Characterization of long cDNA clones from human adult spleen. (PubMed id 11214971)1, 3 Hattori A.... Ohara O. (DNA Res. 2000)
    9. Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks. (PubMed id 22558309)1 Wong K.A....O'Bryan J.P. (PLoS ONE 2012)
    10. The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment. (PubMed id 20467438)1 Arbuckle M.I....Grant S.G. (EMBO Rep. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 89848 HGNC: 25463 AceView: FCHSD1 Ensembl:ENSG00000197948 euGenes: HUgn89848
    ECgene: FCHSD1 H-InvDB: FCHSD1

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for FCHSD1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for FCHSD1 gene:
    Search GeneIP for patents involving FCHSD1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for FCHSD1   OriGene RNAi products in human, mouse, rat for FCHSD1  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for FCHSD1  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for FCHSD1  
     OriGene qSTAR qPCR primer pairs in human, mouse for FCHSD1   OriGene Purified Protein for FCHSD1  
     OriGene ORF clones in mouse, rat for FCHSD1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for FCHSD1   OriGene Custom Protein Services for FCHSD1  

     
     
     Block miRNA regulation of human, mouse, rat FCHSD1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing FCHSD1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FCHSD1 Predesigned siRNA for gene silencing in human, mouse, rat FCHSD1
     QuantiFast Probe-based Assays in human, mouse, rat FCHSD1 QuantiTect SYBR Green Assays in human, mouse, rat FCHSD1
     Custom PCR Arrays for FCHSD1 Search Chromatin IP Primers for FCHSD1
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FCHSD1  Search GeneGlobe Interaction Network for FCHSD1
     Regulatory tfbs in FCHSD1 promoter
     GenScript Custom Purified and Recombinant Proteins Services for FCHSD1 GenScript cDNA clones with any tag delivered in your preferred vector for FCHSD1
     GenScript Custom Assay Services for FCHSD1 GenScript Custom overexpressing Cell Line Services for FCHSD1
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for FCHSD1 (FCSD1)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     FCHSD1 antibodies
     FCHSD1 proteins
     FCHSD1 lysates
     Antibodies for FCHSD1
     See all of Abcam's Antibodies, Kits and Proteins for FCHSD1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for FCHSD1
     Antibodies for FCHSD1
     ELISAs for FCHSD1
     CLIAs for FCHSD1



     Browse ESI BIO Cell Lines and PureStem Progenitors for FCHSD1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FCHSD1
     SwitchGear 3'UTR luciferase reporter plasmids for FCHSD1
     SwitchGear Promoter luciferase reporter plasmids for FCHSD1
     Search ThermoFisher Antibodies for FCHSD1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FCHSD1
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FCHSD1
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FCHSD1
     LSBio Antibodies in human, mouse, rat for FCHSD1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      FCHSD1 gene at Home site.
    Version: 3.12.162 20 Aug 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4