Aliases for FCHO2 Gene
External Ids for FCHO2 Gene
- HGNC: 25180
- Entrez Gene: 115548
- Ensembl: ENSG00000157107
- OMIM: 613438
- UniProtKB: Q0JRZ9
Previous GeneCards Identifiers for FCHO2 Gene
- GC05P072287
- GC05P067457
Summaries for FCHO2 Gene
GeneCards Summary for FCHO2 Gene
FCHO2 (FCH Domain Only 2) is a Protein Coding gene. Among its related pathways are Vesicle-mediated transport and Clathrin-mediated endocytosis. GO annotations related to this gene include phosphatidylinositol binding and phosphatidylserine binding. An important paralog of this gene is FCHO1.
UniProtKB/Swiss-Prot for FCHO2 Gene
-
Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) like the plasma membrane. Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles. Involved in adaptor protein complex AP-2-dependent endocytosis of the transferin receptor, it also functions in the AP-2-independent endocytosis of the LDL receptor.
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FCHO2 Gene
Genomics for FCHO2 Gene
Regulatory Elements for FCHO2 Gene
Enhancers for FCHO2 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FCHO2 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for FCHO2 Gene
- Chromosome:
- 5
- Start:
- 72,955,981 bp from pter
- End:
- 73,090,522 bp from pter
- Size:
- 134,542 bases
- Orientation:
- Plus strand
Genomic View for FCHO2 Gene
Genes around FCHO2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 5q13.2 by Ensembl
- 5q13.2 by Entrez Gene
- 5q13.2 by HGNC
FCHO2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FCHO2 Gene
Proteins for FCHO2 Gene
-
Protein details for FCHO2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q0JRZ9-FCHO2_HUMAN
- Recommended name:
- F-BAR domain only protein 2
- Protein Accession:
- Q0JRZ9
- A8K6W7
- B2RNQ9
- B4DHK0
- E9PG79
- Q0JTJ3
- Q96CF5
Protein attributes for FCHO2 Gene
- Size:
- 810 amino acids
- Molecular mass:
- 88924 Da
- Quaternary structure:
-
- Homodimer; disulfide-linked. May form homotetramer. Interacts with AP2A1. Interacts with EPS15, EPS15R, ITSN1 and ITSN2; recruit those scaffolding proteins which in turn may interact with the adaptor protein complex AP-2 at the plasma membrane. Interacts with DAB2 (via DPF motifs); mediates LDL receptor/LDLR endocytosis.
- Miscellaneous:
-
- Deforms liposomes into a range of tubule diameters from 20 to 130 nm in vitro.
- SequenceCaution:
-
- Sequence=AAH14311.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
Protein Expression for FCHO2 Gene
Post-translational modifications for FCHO2 Gene
- Ubiquitinated. Mainly undergoes monoubiquitination but also polyubiquitination (By similarity).
- Ubiquitination at isoforms=2, 358
- Modification sites at PhosphoSitePlus
Other Protein References for FCHO2 Gene
Antibody Products
- Novus Biologicals Antibodies for FCHO2
- Invitrogen Antibodies for FCHO2
- antibodies-online Antibodies for FCHO2: See all 27
- GeneTex FCHO2 antibody for FCHO2
-
Custom Antibody ServicesProSci Antibodies for FCHO2
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for FCHO2
- Origene Custom Protein Services for FCHO2
- Novus Biologicals proteins for FCHO2
- Search GeneTex for Proteins for FCHO2
Assay Products
No data available for DME Specific Peptides for FCHO2 Gene
Domains & Families for FCHO2 Gene
Gene Families for FCHO2 Gene
Protein Domains for FCHO2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for FCHO2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q0JRZ9- Family:
-
- Belongs to the FCHO family.
Function for FCHO2 Gene
Molecular function for FCHO2 Gene
- UniProtKB/Swiss-Prot Function:
- Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) like the plasma membrane. Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles. Involved in adaptor protein complex AP-2-dependent endocytosis of the transferin receptor, it also functions in the AP-2-independent endocytosis of the LDL receptor.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001786 | phosphatidylserine binding | ISS | -- |
| GO:0005515 | protein binding | IPI | 19380743 |
| GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding | ISS | -- |
| GO:0035091 | phosphatidylinositol binding | ISS | -- |
Phenotypes for FCHO2 Gene
- GenomeRNAi human phenotypes for FCHO2:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for FCHO2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FCHO2 gene
- Search ViGene Biosciences for FCHO2
CRISPR Products
-
OriGene CRISPR knockouts for FCHO2
-
Santa Cruz Biotechnology (SCBT) CRISPR for FCHO2
- GenScript: Design CRISPR guide RNA sequences for FCHO2
miRNA for FCHO2 Gene
- miRTarBase miRNAs that target FCHO2
-
- hsa-mir-124-3p (MIRT002703)
- hsa-mir-93-5p (MIRT028083)
- hsa-mir-181d-5p (MIRT041166)
- hsa-mir-17-5p (MIRT097127)
- hsa-mir-20a-5p (MIRT097128)
- hsa-mir-33a-3p (MIRT097129)
- hsa-mir-106a-5p (MIRT097130)
- hsa-mir-106b-5p (MIRT097131)
- hsa-mir-20b-5p (MIRT097132)
- hsa-mir-409-3p (MIRT097133)
- hsa-mir-526b-3p (MIRT097134)
- hsa-mir-519d-3p (MIRT097135)
- hsa-mir-548t-5p (MIRT097136)
- hsa-mir-3674 (MIRT097137)
- hsa-mir-548az-5p (MIRT097138)
- hsa-mir-6736-3p (MIRT097139)
- hsa-mir-32-5p (MIRT097147)
- hsa-mir-92a-3p (MIRT097148)
- hsa-mir-92b-3p (MIRT097151)
- hsa-mir-519c-3p (MIRT097158)
- hsa-mir-519b-3p (MIRT097159)
- hsa-mir-519a-3p (MIRT097160)
- hsa-mir-3680-5p (MIRT166946)
- hsa-mir-340-5p (MIRT166963)
- hsa-mir-548c-3p (MIRT166971)
- hsa-mir-552-5p (MIRT314310)
- hsa-mir-1273e (MIRT444651)
- hsa-mir-200b-5p (MIRT444652)
- hsa-mir-3163 (MIRT444653)
- hsa-mir-200a-5p (MIRT444654)
- hsa-mir-8068 (MIRT537400)
- hsa-mir-548n (MIRT537401)
- hsa-mir-5583-5p (MIRT557898)
- hsa-mir-3129-3p (MIRT557899)
miRNA Products
- Search ViGene Biosciences for FCHO2
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FCHO2
- Browse OriGene Inhibitory RNA Products For FCHO2
-
ViGene Biosciences ready-to-package AAV shRNAs for FCHO2 gene
Cell Line Products
-
Horizon Cell Lines for FCHO2
-
ViGene Biosciences adenoviral particle packaged cDNA for FCHO2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FCHO2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FCHO2 gene
Flow Cytometry Products
- eBioscience FlowRNA Probe Sets (VA1-11974) for FCHO2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FCHO2 Gene
Localization for FCHO2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for FCHO2 Gene
- Membrane, clathrin-coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Associated with forming but not mature clathrin-coated vesicles. The recruitment to coated-pits precede the one of clathrin and the adaptor protein complex AP-2 (By similarity). {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| plasma membrane | 4 |
| nucleus | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005829 | cytosol | TAS | -- |
| GO:0005886 | plasma membrane | ISS | -- |
| GO:0005905 | clathrin-coated pit | IEA,IDA | 21762413 |
| GO:0016020 | membrane | IEA | -- |
| GO:0030136 | clathrin-coated vesicle | IDA | 21762413 |
Pathways & Interactions for FCHO2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Clathrin-mediated endocytosis | ||
| 2 | Vesicle-mediated transport | ||
Pathways by source for FCHO2 Gene
4 Reactome pathways for FCHO2 Gene
Interacting Proteins for FCHO2 Gene
Selected Interacting proteins:
ENSP00000393776
Q0JRZ9-FCHO2_HUMAN
for FCHO2 Gene via
STRING
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006897 | endocytosis | IEA | -- |
| GO:0010324 | membrane invagination | ISS | -- |
| GO:0048268 | clathrin coat assembly | IMP | 20448150 |
| GO:0048488 | synaptic vesicle endocytosis | IEA | -- |
| GO:0061024 | membrane organization | TAS | -- |
No data available for SIGNOR curated interactions for FCHO2 Gene
Transcripts for FCHO2 Gene
mRNA/cDNA for FCHO2 Gene
- (10) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (88) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for FCHO2
-
Santa Cruz Biotechnology (SCBT) CRISPR for FCHO2
- GenScript: Design CRISPR guide RNA sequences for FCHO2
miRNA Products
- Search ViGene Biosciences for FCHO2
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FCHO2
- Browse OriGene Inhibitory RNA Products For FCHO2
-
ViGene Biosciences ready-to-package AAV shRNAs for FCHO2 gene
Flow Cytometry Products
- eBioscience FlowRNA Probe Sets (VA1-11974) for FCHO2
Expression for FCHO2 Gene
This gene is overexpressed in Cervix (23.0), Plasma (9.4), Spleen (7.4), and Serum (7.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for FCHO2 Gene
NURSA nuclear receptor signaling pathways regulating expression of FCHO2 Gene:
FCHO2SOURCE GeneReport for Unigene cluster for FCHO2 Gene:
Hs.165762Evidence on tissue expression from TISSUES for FCHO2 Gene
- Lung(4.3)
- Liver(4.2)
- Muscle(4.2)
- Nervous system(4.2)
Primer Products
-
OriGene qPCR primer pairs for FCHO2
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FCHO2 Gene
Orthologs for FCHO2 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FCHO2 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | FCHO2 35 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | FCHO2 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Fcho2 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Fcho2 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | FCHO2 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
ManyToMany | |
| chicken (Gallus gallus) |
Aves | FCHO2 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | FCHO2 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | fcho2 34 |
|
||
| Str.1488 34 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.33576 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | fcho2 34 |
|
||
| si:dkey-24m12.3 35 |
|
ManyToMany | |||
| sbcb304 34 |
|
||||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP002024 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG8176 35 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | fcho-1 35 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToMany |
- Species where no ortholog for FCHO2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for FCHO2 Gene
(18) SIMAP similar genes for FCHO2 Gene using alignment to 5 proteins:
Pseudogenes.org Pseudogenes for FCHO2 Gene
Variants for FCHO2 Gene
| SNP ID | Clin | Chr 05 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000008113 | -- | 72,974,488(+) | TTGTT(-/G)GTTTA | intron-variant | |
| rs1000015106 | -- | 73,074,244(+) | AAAGT(A/C)ATGTG | intron-variant | |
| rs1000042595 | -- | 73,030,205(+) | CCCAG(C/T)TAATT | intron-variant | |
| rs1000064934 | -- | 72,982,378(+) | CCCCT(C/T)ATTGG | intron-variant | |
| rs1000092244 | -- | 73,036,697(+) | ATGGG(A/C/T)CTGCT | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2730298 | CNV | deletion | 23290073 |
| esv2730299 | CNV | deletion | 23290073 |
| esv27712 | CNV | loss | 19812545 |
| esv3310324 | CNV | mobile element insertion | 20981092 |
| esv3358480 | CNV | insertion | 20981092 |
| esv3394174 | CNV | insertion | 20981092 |
| esv3605410 | CNV | loss | 21293372 |
| nsv525479 | CNV | loss | 19592680 |
| nsv830343 | CNV | loss | 17160897 |
| nsv980683 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
35.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.14;
75.68% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FCHO2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- FCHO2
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FCHO2 Gene
Disorders for FCHO2 Gene
Relevant External Links for FCHO2
No disorders were found for FCHO2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FCHO2 Gene
Publications for FCHO2 Gene
- FCH domain only-2 organizes clathrin-coated structures and interacts with Disabled-2 for low-density lipoprotein receptor endocytosis. (PMID: 22323290) Mulkearns E.E. … Cooper J.A. (Mol. Biol. Cell 2012) 3 4 64
- Distinct and separable activities of the endocytic clathrin-coat components Fcho1/2 and AP-2 in developmental patterning. (PMID: 22484487) Umasankar P.K. … Traub L.M. (Nat. Cell Biol. 2012) 3 4 64
- Characterization of the EFC/F-BAR domain protein, FCHO2. (PMID: 21762413) Uezu A. … Nakanishi H. (Genes Cells 2011) 3 4 64
- FCHo proteins are nucleators of clathrin-mediated endocytosis. (PMID: 20448150) Henne W.M. … McMahon H.T. (Science 2010) 3 4 64
- Structure and analysis of FCHo2 F-BAR domain: a dimerizing and membrane recruitment module that effects membrane curvature. (PMID: 17540576) Henne W.M. … McMahon H.T. (Structure 2007) 3 4 64
Products for FCHO2 Gene
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- Browse R&D Systems for biochemical assays
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- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for FCHO2
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- OriGene qPCR primer pairs for FCHO2
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- GenScript: Design CRISPR guide RNA sequences for FCHO2
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Gene Mutant Library, Variants up to 10^11
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for FCHO2
- Novus Biologicals proteins for FCHO2
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ViGene Biosciences adenoviral particle packaged cDNA for FCHO2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for FCHO2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for FCHO2 gene
- Search ViGene Biosciences for FCHO2
- Custom Antibody ServicesProSci Antibodies for FCHO2
- Search for FCHO2 Proteins at ProSci
- Horizon Cell Lines for FCHO2
- Cyagen custom Knockout/knockin (KOKI) mouse models for FCHO2
- VectorBuilder custom plasmid, inducible vectors for FCHO2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FCHO2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FCHO2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
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- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer