Aliases for FCGRT Gene
External Ids for FCGRT Gene
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
GeneCards Summary for FCGRT Gene
FCGRT (Fc Fragment Of IgG, Receptor, Transporter, Alpha) is a Protein Coding gene. Diseases associated with FCGRT include persistent fetal circulation syndrome and hypoproteinemia, hypercatabolic. GO annotations related to this gene include antigen binding and beta-2-microglobulin binding. An important paralog of this gene is MR1.
UniProtKB/Swiss-Prot for FCGRT Gene
Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus