Aliases for FCGRT Gene
Aliases for FCGRT Gene
- Fc Fragment Of IgG Receptor And Transporter 2 3 5
- Heavy Chain Of The Major Histocompatibility Complex Class I-Like Fc Receptor 2 3
- Transmembrane Alpha Chain Of The Neonatal Receptor 2 3
- Fc Fragment Of IgG, Receptor, Transporter, Alpha 2 3
- IgG Fc Fragment Receptor Transporter Alpha Chain 3 4
- Neonatal Fc Receptor 3 4
- FCRN 3 4
External Ids for FCGRT Gene
- HGNC: 3621
- Entrez Gene: 2217
- Ensembl: ENSG00000104870
- OMIM: 601437
- UniProtKB: P55899
Previous GeneCards Identifiers for FCGRT Gene
- GC19P050674
- GC19P050384
- GC19P054691
- GC19P054707
- GC19P054708
- GC19P050015
- GC19P046393
- GC19P050028
- GC19P050047
Summaries for FCGRT Gene
-
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
GeneCards Summary for FCGRT Gene
FCGRT (Fc Fragment Of IgG Receptor And Transporter) is a Protein Coding gene. Diseases associated with FCGRT include Hypoproteinemia, Hypercatabolic and Immunoglobulin G Deficiency. GO annotations related to this gene include antigen binding and beta-2-microglobulin binding. An important paralog of this gene is MICA.
UniProtKB/Swiss-Prot for FCGRT Gene
-
Binds to the Fc region of monomeric immunoglobulins gamma (PubMed:7964511, PubMed:10933786). Mediates the selective uptake of IgG from milk and helps newborn animals to acquire passive immunity. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids (By similarity). Possible role in transfer of immunoglobulin G from mother to fetus (PubMed:7964511).
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FCGRT Gene
Genomics for FCGRT Gene
Regulatory Elements for FCGRT Gene
Enhancers for FCGRT Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FCGRT on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the FCGRT gene promoter:
Regulatory Element Products
Genomic Location for FCGRT Gene
- Chromosome:
- 19
- Start:
- 49,506,816 bp from pter
- End:
- 49,526,428 bp from pter
- Size:
- 19,613 bases
- Orientation:
- Plus strand
Genomic View for FCGRT Gene
Genes around FCGRT on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.33 by Ensembl
- 19q13.33 by Entrez Gene
- 19q13.33 by HGNC
FCGRT Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FCGRT Gene
Proteins for FCGRT Gene
-
Protein details for FCGRT Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P55899-FCGRN_HUMAN
- Recommended name:
- IgG receptor FcRn large subunit p51
- Protein Accession:
- P55899
- Q5HYM5
- Q9HBV7
- Q9NZ19
Protein attributes for FCGRT Gene
- Size:
- 365 amino acids
- Molecular mass:
- 39743 Da
- Quaternary structure:
-
- FcRn complex consist of two subunits: p51, and p14 which is equivalent to beta-2-microglobulin. It forms an MHC class I-like heterodimer.
Protein Expression for FCGRT Gene
Post-translational modifications for FCGRT Gene
Other Protein References for FCGRT Gene
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for FCGRT
- R&D Systems Antibodies for FCGRT (FCRN)
-
Custom Antibody ServicesOriGene Antibodies for FCGRT
- Novus Biologicals Antibodies for FCGRT
-
Cloud-Clone Corp. Antibodies for FCGRT
- Invitrogen Antibodies for FCGRT
- antibodies-online Antibodies for FCGRT: See all 48
- GeneTex FCGRT antibody for FCGRT
-
Santa Cruz Biotechnology (SCBT) Antibodies for FCGRT
Protein Products
- R&D Systems Proteins and Enzymes for FCGRT (FCRN)
-
OriGene Purified Proteins for FCGRT
- Search Origene for MassSpec and Protein Over-expression Lysates for FCGRT
- Origene Custom Protein Services for FCGRT
-
Cloud-Clone Corp. Proteins for FCGRT
- antibodies-online Proteins for FCGRT: See all 14
- Search antibodies-online for peptides
- Search GeneTex for Proteins for FCGRT
-
ProSci Proteins for FCGRT
No data available for DME Specific Peptides for FCGRT Gene
Domains & Families for FCGRT Gene
Gene Families for FCGRT Gene
Protein Domains for FCGRT Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for FCGRT Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P55899- Family:
-
- Belongs to the immunoglobulin superfamily.
Function for FCGRT Gene
Molecular function for FCGRT Gene
- GENATLAS Biochemistry:
- MHC,class I-like FC receptor,FCGRT
- UniProtKB/Swiss-Prot Function:
- Binds to the Fc region of monomeric immunoglobulins gamma (PubMed:7964511, PubMed:10933786). Mediates the selective uptake of IgG from milk and helps newborn animals to acquire passive immunity. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids (By similarity). Possible role in transfer of immunoglobulin G from mother to fetus (PubMed:7964511).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003823 | antigen binding | IBA | -- |
| GO:0019770 | IgG receptor activity | IBA | -- |
| GO:0019864 | IgG binding | IDA,IEA | 7964511 |
| GO:0030881 | beta-2-microglobulin binding | IBA | -- |
| GO:0042605 | NOT peptide antigen binding | ISS | -- |
Phenotypes for FCGRT Gene
- MGI mutant phenotypes for FCGRT:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for FCGRT:
-
- Increased viability
- Increased vaccinia virus (VACV) infection
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased JFH-1 genotype 2a Hepatitis C virus (HCV) infection
- Decreased human papilloma virus 16 (HPV16) pseudovirus infection
- Increased transferrin (TF) endocytosis
- Decreased viability
- Decreased JFH-1 genotype 2a Hepatitis C virus (HCV) infection after viral supernatant infection
- Decreased JFH-1 genotype 2a Hepatitis C virus (HCV) infection after direct virus infection
- Decreased vesicular stomatitis virus (VSV) infection
Animal Models for FCGRT Gene
- MGI Knock Outs for FCGRT:
-
- Fcgrt tm1Dcr
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for FCGRT gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FCGRT gene
- Search ViGene Biosciences for FCGRT
CRISPR Products
-
OriGene CRISPR knockouts for FCGRT
-
Santa Cruz Biotechnology (SCBT) CRISPR for FCGRT
- GenScript: Design CRISPR guide RNA sequences for FCGRT
miRNA for FCGRT Gene
- miRTarBase miRNAs that target FCGRT
miRNA Products
- Search ViGene Biosciences for FCGRT
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for FCGRT
- Browse OriGene Inhibitory RNA Products For FCGRT
-
ViGene Biosciences ready-to-package AAV shRNAs for FCGRT gene
Clone Products
- Sino Biological Human cDNA Clone for FCGRT
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- R&D Systems cDNA Clones for FCGRT (FCRN)
Cell Line Products
-
Horizon Cell Lines for FCGRT
-
ViGene Biosciences adenoviral particle packaged cDNA for FCGRT gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FCGRT gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FCGRT gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for FCGRT Gene
Localization for FCGRT Gene
Subcellular locations from UniProtKB/Swiss-Prot for FCGRT Gene
- Cell membrane; Single-pass type I membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 3 |
| cytosol | 2 |
| lysosome | 2 |
| endosome | 2 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | IEA,IBA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for FCGRT Gene
No Data Available
Interacting Proteins for FCGRT Gene
Selected Interacting proteins:
P55899-FCGRN_HUMAN
ENSP00000221466
for FCGRT Gene via
IID
STRING
MINT
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002416 | IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor | NAS | 7964511 |
| GO:0019882 | antigen processing and presentation | IBA | -- |
| GO:0038094 | Fc-gamma receptor signaling pathway | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for FCGRT Gene
Transcripts for FCGRT Gene
mRNA/cDNA for FCGRT Gene
- (4) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (31) Selected AceView cDNA sequences:
- (18) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FCGRT Gene
- Fc fragment of IgG, receptor, transporter, alpha:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for FCGRT
-
Santa Cruz Biotechnology (SCBT) CRISPR for FCGRT
- GenScript: Design CRISPR guide RNA sequences for FCGRT
miRNA Products
- Search ViGene Biosciences for FCGRT
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for FCGRT
- Browse OriGene Inhibitory RNA Products For FCGRT
-
ViGene Biosciences ready-to-package AAV shRNAs for FCGRT gene
Clone Products
- Sino Biological Human cDNA Clone for FCGRT
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- R&D Systems cDNA Clones for FCGRT (FCRN)
Flow Cytometry Products
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5a | · | 5b | · | 5c | · | 5d | · | 5e | ^ | 6 | ^ | 7a | · | 7b | · | 7c | · | 7d | · | 7e | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP13: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP14: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP15: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP16: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP17: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP18: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP19: | - | - | - | - | - |
| ExUns: | 12 | ^ | 13 | ^ | 14a | · | 14b | · | 14c | ^ | 15a | · | 15b | ^ | 16a | · | 16b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||
| SP2: | |||||||||||||||||
| SP3: | - | - | - | ||||||||||||||
| SP4: | |||||||||||||||||
| SP5: | |||||||||||||||||
| SP6: | |||||||||||||||||
| SP7: | - | ||||||||||||||||
| SP8: | |||||||||||||||||
| SP9: | |||||||||||||||||
| SP10: | |||||||||||||||||
| SP11: | |||||||||||||||||
| SP12: | - | ||||||||||||||||
| SP13: | - | - | |||||||||||||||
| SP14: | |||||||||||||||||
| SP15: | |||||||||||||||||
| SP16: | - | - | - | - | - | - | - | ||||||||||
| SP17: | |||||||||||||||||
| SP18: | - | - | - | - | - | - | |||||||||||
| SP19: | - |
Expression for FCGRT Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Common Dendritic Cell Precursors Hematopoietic Bone Marrow
- Neural Tube (Nervous System)
- Intestine (Gastrointestinal Tract)
- Bone (Muscoskeletal System)
-
Uterus (Reproductive System)
-
Colon (Gastrointestinal Tract)
-
Prostate (Endocrine System)
-
Placenta (Extraembryonic Tissues)
-
Spleen (Hematopoietic System)
-
Thyroid (Endocrine System)
-
Gall Bladder (Hepatobiliary System)
-
Lung (Respiratory System)
-
Kidney (Urinary System)
-
Adrenal Gland (Endocrine System)
-
Esophagus (Gastrointestinal Tract)
-
Stomach (Gastrointestinal Tract)
-
Liver (Hepatobiliary System)
-
Pancreas (Endocrine System)
-
Ovary (Reproductive System)
-
Adipose (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for FCGRT Gene
This gene is overexpressed in Whole Blood (x6.6).
This gene is overexpressed in Spleen (10.1) and Nasopharynx (6.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for FCGRT Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of FCGRT Gene:
FCGRTSOURCE GeneReport for Unigene cluster for FCGRT Gene:
Hs.111903mRNA Expression by UniProt/SwissProt for FCGRT Gene:
P55899-FCGRN_HUMAN
Tissue specificity:
Expressed in full-term placenta, heart, lung, liver, muscle, kidney, pancreas, and both fetal and adult small intestine.
Evidence on tissue expression from TISSUES for FCGRT Gene
- Nervous system(4.9)
- Lung(4.8)
- Liver(4.5)
- Intestine(3.5)
- Blood(3.1)
- Kidney(2.9)
- Spleen(2.9)
- Lymph node(2.7)
- Heart(2.4)
- Gall bladder(2)
- Skin(2)
Primer Products
-
OriGene qPCR primer pairs and template standards for FCGRT
-
OriGene qPCR primer pairs for FCGRT
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for FCGRT Gene
Orthologs for FCGRT Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FCGRT 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | FCGRT 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | FCGRT 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Fcgrt 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Fcgrt 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | FCGRT 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
OneToMany | |
| chicken (Gallus gallus) |
Aves | BFIV21 35 |
|
ManyToMany | |
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| BF1 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
ManyToMany | |
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany |
- Species where no ortholog for FCGRT was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for FCGRT Gene
(34) SIMAP similar genes for FCGRT Gene using alignment to 10 proteins:
Variants for FCGRT Gene
| SNP ID | Clin | Chr 19 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000021938 | -- | 49,513,479(+) | GTGAG(A/G)GCCGC | intron-variant | |
| rs1000499647 | -- | 49,522,207(+) | CTCCA(A/G)AGTAG | intron-variant | |
| rs1000512107 | -- | 49,518,578(+) | GCCCA(C/G)ACTGG | intron-variant | |
| rs1000910403 | -- | 49,511,136(+) | TGTGG(A/C)TTCTG | upstream-variant-2KB | |
| rs1000946663 | -- | 49,518,197(+) | CATCA(C/T)ACCTA | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3644626 | CNV | loss | 21293372 |
| nsv1160655 | CNV | deletion | 26073780 |
| nsv833862 | CNV | loss | 17160897 |
| nsv833863 | CNV | loss | 17160897 |
| nsv9739 | CNV | gain+loss | 18304495 |
Residual Variation Intolerance Score:
51% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.16;
39.13% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FCGRT Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FCGRT Gene
Disorders for FCGRT Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| hypoproteinemia, hypercatabolic |
|
|
| immunoglobulin g deficiency |
|
|
| persistent fetal circulation syndrome |
|
|
| epidermolysis bullosa acquisita |
|
|
| hemochromatosis |
|
Search FCGRT in MalaCards
View complete list of genes associated with diseases
Relevant External Links for FCGRT
No data available for UniProtKB/Swiss-Prot and Genatlas for FCGRT Gene
Publications for FCGRT Gene
- Association between polymorphisms in the FCGRT gene and lupus nephritis in Chinese patients. (PMID: 19772792) Zhou X.J. … Zhang H. (Clin. Exp. Rheumatol. 2009) 3 22 46 64
- Crystal structure and immunoglobulin G binding properties of the human major histocompatibility complex-related Fc receptor. (PMID: 10933786) West A.P. Jr. … Bjorkman P.J. (Biochemistry 2000) 3 4 22 64
- Cloning and analysis of the gene encoding the human neonatal Fc receptor. (PMID: 10998088) Mikulska J.E. … Simister N.E. (Eur. J. Immunogenet. 2000) 3 4 22 64
- The human gene encoding the heavy chain of the major histocompatibility complex class I-like Fc receptor (FCGRT) maps to 19q13.3. (PMID: 8646894) Kandil E. … Miyosi O. (Cytogenet. Cell Genet. 1996) 2 3 22 64
- A major histocompatibility complex class I-like Fc receptor cloned from human placenta: possible role in transfer of immunoglobulin G from mother to fetus. (PMID: 7964511) Story C.M. … Simister N.E. (J. Exp. Med. 1994) 2 3 4 64
Products for FCGRT Gene
- R&D Systems Antibodies for FCGRT (FCRN)
- R&D Systems Proteins and Enzymes for FCGRT (FCRN)
- Browse R&D Systems for biochemical assays
- R&D Systems cDNA Clones for FCGRT (FCRN)
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for FCGRT
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for FCGRT
- Search Origene for MassSpec and Protein Over-expression Lysates for FCGRT
- Origene Custom Protein Services for FCGRT
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for FCGRT
- Browse OriGene Inhibitory RNA Products For FCGRT
- OriGene qPCR primer pairs and template standards for FCGRT
- OriGene qPCR primer pairs for FCGRT
- OriGene CRISPR knockouts for FCGRT
- OriGene ORF clones in human for FCGRT
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For FCGRT
- GenScript: Next-day shipping cDNA ORF clone for FCGRT in any vector
- GenScript Custom Purified and Recombinant Proteins Services for FCGRT
- GenScript Custom Assay Services for FCGRT
- GenScript Custom overexpressing Cell Line Services for FCGRT
- GenScript: Design CRISPR guide RNA sequences for FCGRT
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for FCGRT
- Sino Biological Human cDNA Clone for FCGRT
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for FCGRT
- Novus Biologicals proteins and lysates for FCGRT
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Cloud-Clone Corp. Antibodies for FCGRT
- Cloud-Clone Corp. Proteins for FCGRT
- Cloud-Clone Corp Assay Kits for FCGRT
- antibodies-online Antibodies for FCGRT: See all 48
- antibodies-online Kits for FCGRT: See all 8
- antibodies-online Proteins for FCGRT: See all 14
- Search antibodies-online for peptides
- GeneTex FCGRT antibody for FCGRT
- Search GeneTex for Proteins for FCGRT
- ViGene Biosciences adenoviral particle packaged cDNA for FCGRT gene
- ViGene Biosciences lentiviral particle packaged cDNA for FCGRT gene
- ViGene Biosciences ready-to-package AAV shRNAs for FCGRT gene
- Search ViGene Biosciences for FCGRT
- Santa Cruz Biotechnology (SCBT) Antibodies for FCGRT
- Search Santa Cruz Biotechnology (SCBT) for FCGRT siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for FCGRT
- Search for FCGRT Antibodies at ProSci
- Custom Antibody Services
- ProSci Proteins for FCGRT
- Horizon Cell Lines for FCGRT
- Cyagen custom Knockout/knockin (KOKI) mouse models for FCGRT
- VectorBuilder custom plasmid, inducible vectors for FCGRT
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FCGRT
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FCGRT Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer