Aliases for FCGR2C Gene
External Ids for FCGR2C Gene
Previous GeneCards Identifiers for FCGR2C Gene
This gene encodes one of three members of a family of low-affinity immunoglobulin gamma Fc receptors found on the surface of many immune response cells. The encoded protein is a transmembrane glycoprotein and may be involved in phagocytosis and clearing of immune complexes. An allelic polymorphism in this gene results in both coding and non-coding variants. [provided by RefSeq, Apr 2012]
GeneCards Summary for FCGR2C Gene
FCGR2C (Fc Fragment Of IgG Receptor IIc (Gene/Pseudogene)) is a Protein Coding gene. Diseases associated with FCGR2C include Thrombocytopenic Purpura, Autoimmune. Among its related pathways are Regulation of actin dynamics for phagocytic cup formation and Toxoplasmosis. GO annotations related to this gene include transmembrane signaling receptor activity and IgG binding. An important paralog of this gene is FCRL2.
UniProtKB/Swiss-Prot for FCGR2C Gene
Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells.