Aliases for FCGR2C Gene
External Ids for FCGR2C Gene
Previous GeneCards Identifiers for FCGR2C Gene
This gene encodes one of three members of a family of low-affinity immunoglobulin gamma Fc receptors found on the surface of many immune response cells. The encoded protein is a transmembrane glycoprotein and may be involved in phagocytosis and clearing of immune complexes. An allelic polymorphism in this gene results in both coding and non-coding variants. [provided by RefSeq, Apr 2012]
GeneCards Summary for FCGR2C Gene
FCGR2C (Fc Fragment Of IgG, Low Affinity IIc, Receptor For (CD32) (Gene/Pseudogene)) is a Protein Coding gene. Diseases associated with FCGR2C include thrombocytopenic purpura, autoimmune and purpura. Among its related pathways are Class I MHC mediated antigen processing and presentation and Staphylococcus aureus infection. GO annotations related to this gene include transmembrane signaling receptor activity and IgG binding.
UniProtKB/Swiss-Prot for FCGR2C Gene
Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells