Aliases for FCGR2B Gene
Aliases for FCGR2B Gene
External Ids for FCGR2B Gene
- HGNC: 3618
- Entrez Gene: 2213
- Ensembl: ENSG00000072694
- OMIM: 604590
- UniProtKB: P31994
Previous HGNC Symbols for FCGR2B Gene
- FCG2
- FCGR2
Previous GeneCards Identifiers for FCGR2B Gene
- GC01P159267
- GC01P157283
- GC01P158328
- GC01P158820
- GC01P158365
- GC01P159899
- GC01P161552
- GC01P132877
Summaries for FCGR2B Gene
-
The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
GeneCards Summary for FCGR2B Gene
FCGR2B (Fc Fragment Of IgG Receptor IIb) is a Protein Coding gene. Diseases associated with FCGR2B include Systemic Lupus Erythematosus and Malaria. Among its related pathways are Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell and Phospholipase-C Pathway. GO annotations related to this gene include IgG binding. An important paralog of this gene is FCGR2C.
UniProtKB/Swiss-Prot for FCGR2B Gene
-
Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FCGR2B Gene
Genomics for FCGR2B Gene
Regulatory Elements for FCGR2B Gene
Enhancers for FCGR2B Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH01G161611 | 2 | FANTOM5 Ensembl ENCODE dbSUPER | 27.7 | -50.8 | -50815 | 2.6 | HDGF PKNOX1 CREB3L1 ARNT SIN3A FEZF1 ZNF2 ZNF766 ZNF143 KLF13 | FCGR2B ATF6 FCGR2C FCGR3B DUSP12 HSPA6 HSPA7 FCRLB FCGR3A GC01P161612 |
| GH01G161620 | 1.9 | FANTOM5 Ensembl ENCODE dbSUPER | 27.8 | -40.0 | -40036 | 4.6 | HDGF PKNOX1 ARNT SIN3A FEZF1 ZNF2 ZNF766 SP3 JUNB REST | FCGR2B FCGR3B ATF6 FCGR3A FCGR2A GC01P161621 |
| GH01G161642 | 1.6 | Ensembl ENCODE dbSUPER | 25.3 | -19.7 | -19715 | 2.8 | HDGF PKNOX1 CREB3L1 ARNT SIN3A FEZF1 ZNF2 ZNF766 KLF13 DEK | FCGR2B FCGR2C ATF6 DUSP12 FCRLB FCGR3B HSPA7 |
| GH01G161649 | 1.1 | dbSUPER | 28.2 | -12.2 | -12177 | 1.9 | HDGF PKNOX1 ARNT SIN3A FEZF1 ZNF2 ZNF766 KLF13 SP3 REST | FCGR2B FCGR3B HSPA7 ATF6 |
| GH01G161635 | 1.1 | Ensembl dbSUPER | 28.1 | -27.0 | -27015 | 1.8 | HDAC1 PKNOX1 ARNT ZBTB40 CEBPB ZEB2 ZNF592 MEF2D CREB3 MTA1 | FCGR2B FCGR3B |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FCGR2B on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the FCGR2B gene promoter:
Regulatory Element Products
Genomic Location for FCGR2B Gene
- Chromosome:
- 1
- Start:
- 161,663,115 bp from pter
- End:
- 161,678,654 bp from pter
- Size:
- 15,540 bases
- Orientation:
- Plus strand
Genomic View for FCGR2B Gene
Genes around FCGR2B on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1q23.3 by Ensembl
- 1q23.3 by Entrez Gene
- 1q23.3 by HGNC
FCGR2B Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FCGR2B Gene
Proteins for FCGR2B Gene
-
Protein details for FCGR2B Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P31994-FCG2B_HUMAN
- Recommended name:
- Low affinity immunoglobulin gamma Fc region receptor II-b
- Protein Accession:
- P31994
- A6H8N3
- O95649
- Q53X85
- Q5VXA9
- Q8NIA1
Protein attributes for FCGR2B Gene
- Size:
- 310 amino acids
- Molecular mass:
- 34044 Da
- Quaternary structure:
-
- Isoform IIB1 interacts with measles virus N protein. N protein is released in the blood following lysis of measles infected cells. This interaction presumably block inflammatory immune response. Interacts with INPP5D/SHIP1. Interacts with FGR. Interacts with LYN.
- SequenceCaution:
-
- Sequence=CAA35645.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Protein Expression for FCGR2B Gene
Post-translational modifications for FCGR2B Gene
- Phosphorylated by the SRC-type Tyr-kinases LYN and BLK.
- Glycosylation at Asn106, Asn180, and isoforms=2, 3187
- Modification sites at PhosphoSitePlus
Other Protein References for FCGR2B Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for FCGR2B
- R&D Systems Antibodies for FCGR2B (Fc gamma RIIB/C (CD32b/c))
- R&D Systems Antibodies for FCGR2B (Fc gamma RIIB/CD32b)
-
Custom Antibody ServicesOriGene Antibodies for FCGR2B
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- antibodies-online Antibodies for FCGR2B: See all 84
- GeneTex FCGR2B antibody for FCGR2B
-
Santa Cruz Biotechnology (SCBT) Antibodies for FCGR2B
Protein Products
- R&D Systems Proteins and Enzymes for FCGR2B (Fc gamma RIIB/CD32b)
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- Sino Biological Cell Lysates for FCGR2B
- ProSpec Recombinant Proteins for FCGR2B
- antibodies-online Proteins for FCGR2B: See all 22
- Search antibodies-online for peptides
- Search GeneTex for Proteins for FCGR2B
-
ProSci Proteins for FCGR2B
Assay Products
-
Custom Assay ServicesOriGene ELISA Kits for FCGR2B
- R&D Systems ELISAs and other biochemical assays for FCGR2B (Fc gamma RIIB/C (CD32b/c))
- R&D Systems ELISAs and other biochemical assays for FCGR2B (Fc gamma RIIB/CD32b)
- antibodies-online Kits for FCGR2B: See all 28
-
Abcam assays for FCGR2B
No data available for DME Specific Peptides for FCGR2B Gene
Domains & Families for FCGR2B Gene
Gene Families for FCGR2B Gene
Protein Domains for FCGR2B Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for FCGR2B Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P31994UniProtKB/Swiss-Prot:
FCG2B_HUMAN :- Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
- Domain:
-
- Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
Function for FCGR2B Gene
Molecular function for FCGR2B Gene
- GENATLAS Biochemistry:
- immunoglobulin G,low affinity Fc receptor 2B (see IGFCR),maintaining gamma immune system homeostasis through negative regulation of immune responses mediated by receptors that bear the I,dysregulated by chromosomal translocation in malignant lymphoma
- UniProtKB/Swiss-Prot Function:
- Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 8577729 |
| GO:0019864 | IgG binding | IEA | -- |
Phenotypes for FCGR2B Gene
- MGI mutant phenotypes for FCGR2B:
-
inferred from 5 alleles
- mortality/aging
- cellular phenotype
- behavior/neurological phenotype
- normal phenotype
- growth/size/body region phenotype
- immune system phenotype
- nervous system phenotype
- homeostasis/metabolism phenotype
- cardiovascular system phenotype
- respiratory system phenotype
- digestive/alimentary phenotype
- endocrine/exocrine gland phenotype
- skeleton phenotype
- hematopoietic system phenotype
- renal/urinary system phenotype
- liver/biliary system phenotype
- GenomeRNAi human phenotypes for FCGR2B:
Animal Models for FCGR2B Gene
Animal Model Products
-
Taconic Biosciences Mouse Models for FCGR2B
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CRISPR Products
-
OriGene CRISPR knockouts for FCGR2B
-
Santa Cruz Biotechnology (SCBT) CRISPR for FCGR2B
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miRNA for FCGR2B Gene
- miRTarBase miRNAs that target FCGR2B
miRNA Products
- Search ViGene Biosciences for FCGR2B
Inhibitory RNA Products
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Clone Products
-
OriGene ORF clones in human for FCGR2B
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Cell Line Products
-
Horizon Cell Lines for FCGR2B
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for FCGR2B Gene
Localization for FCGR2B Gene
Subcellular locations from UniProtKB/Swiss-Prot for FCGR2B Gene
- Cell membrane; Single-pass type I membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 3 |
| cytosol | 2 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| peroxisome | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for FCGR2B Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | B cell receptor signaling pathway (KEGG) | ||
| 2 | Fc-GammaR Pathway | ||
| 3 | Immune response Fc epsilon RI pathway | ||
| 4 | Fc gamma R-mediated phagocytosis | ||
| 5 | Influenza A |
.34
|
|
Pathways by source for FCGR2B Gene
1 Sino Biological pathway for FCGR2B Gene
2 BioSystems pathways for FCGR2B Gene
3 Reactome pathways for FCGR2B Gene
7 KEGG pathways for FCGR2B Gene
1 GeneGo (Thomson Reuters) pathway for FCGR2B Gene
1 R&D Systems pathway for FCGR2B Gene
4 Qiagen pathways for FCGR2B Gene
Interacting Proteins for FCGR2B Gene
Selected Interacting proteins:
P31994-FCG2B_HUMAN
ENSP00000351497
for FCGR2B Gene via
IID
UniProtKB
STRING
MINT
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006955 | immune response | TAS | 2142460 |
| GO:0007165 | signal transduction | TAS | 2142460 |
| GO:0016032 | viral process | IEA | -- |
| GO:0050776 | regulation of immune response | TAS | -- |
No data available for SIGNOR curated interactions for FCGR2B Gene
Drugs & Compounds for FCGR2B Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Abciximab | Approved | Pharma | Target | 65 | ||
| Adalimumab | Approved | Pharma | Target | 494 | ||
| Alefacept | Approved, Withdrawn | Pharma | Target | 40 | ||
| alemtuzumab | Approved, Investigational | Pharma | Target | Therapeutic Antibodies | 310 | |
| Anti-thymocyte Globulin (Rabbit) | Approved | Pharma | Target | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Transcripts for FCGR2B Gene
mRNA/cDNA for FCGR2B Gene
- (10) REFSEQ mRNAs :
- (35) Additional mRNA sequences :
- (509) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FCGR2B Gene
CRISPR Products
-
OriGene CRISPR knockouts for FCGR2B
-
Santa Cruz Biotechnology (SCBT) CRISPR for FCGR2B
- GenScript: Design CRISPR guide RNA sequences for FCGR2B
miRNA Products
- Search ViGene Biosciences for FCGR2B
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FCGR2B
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Clone Products
-
OriGene ORF clones in human for FCGR2B
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for FCGR2B
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Flow Cytometry Products
Expression for FCGR2B Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Liver (Hepatobiliary System)
- Mature Mesothelial Cells Liver Lobule
-
Eye (Sensory Organs)
- Adult Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
-
Epithelial Cells
- Adult Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
-
Blood (Hematopoietic System)
- Mature B-Cells Peripheral Blood
- Kidney (Urinary System)
-
Placenta (Extraembryonic Tissues)
mRNA differential expression in normal tissues according to GTEx for FCGR2B Gene
This gene is overexpressed in Whole Blood (x6.8).
This gene is overexpressed in Blymphocyte (47.4), Placenta (10.0), and Urinary Bladder (8.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for FCGR2B Gene
NURSA nuclear receptor signaling pathways regulating expression of FCGR2B Gene:
FCGR2BSOURCE GeneReport for Unigene cluster for FCGR2B Gene:
Hs.654395mRNA Expression by UniProt/SwissProt for FCGR2B Gene:
P31994-FCG2B_HUMAN
Tissue specificity:
Is the most broadly distributed Fc-gamma-receptor. Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells). Not detected in natural killer cells.
Evidence on tissue expression from TISSUES for FCGR2B Gene
- Blood(4.6)
- Skin(4.4)
- Lymph node(2.9)
- Spleen(2.8)
- Heart(2.1)
- Bone marrow(2)
Primer Products
-
OriGene qPCR primer pairs for FCGR2B
-
OriGene qPCR primer pairs and template standards for FCGR2B
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for FCGR2B Gene
Orthologs for FCGR2B Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FCGR2B 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | FCGR2B 34 |
|
||
| -- 35 |
|
OneToMany | |||
| mouse (Mus musculus) |
Mammalia | Fcgr2b 34 16 35 |
|
||
| Fcgr3 35 |
|
ManyToMany | |||
| cow (Bos Taurus) |
Mammalia | FCGR2C 34 35 |
|
||
| FCGR2 35 |
|
ManyToMany | |||
| rat (Rattus norvegicus) |
Mammalia | Fcgr2b 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
ManyToMany | |
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
OneToMany |
- Species where no ortholog for FCGR2B was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for FCGR2B Gene
Paralogs for FCGR2B Gene
(14) SIMAP similar genes for FCGR2B Gene using alignment to 4 proteins:
Variants for FCGR2B Gene
Polymorphic Variants from UniProtKB/Swiss-Prot for FCGR2B Gene
- FCG2B_HUMAN-P31994
- Note=FCGR2B polymorphisms can influence susceptibility or resistance to malaria [MIM:611162].
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1050501 | other | 161,674,008(+) | TGGGA(C/T)TGCTG | downstream-variant-500B, reference, missense | |
| rs1000035949 | -- | 161,660,013(+) | CTTTC(A/C)CTTTC | intron-variant | |
| rs1000428236 | -- | 161,656,154(+) | GCCCA(C/G)CCTCA | intron-variant | |
| rs1001028923 | -- | 161,651,316(+) | TTCTT(C/T)TGCCA | intron-variant | |
| rs1001099411 | -- | 161,677,783(+) | ACATC(A/T)AGGCT | utr-variant-3-prime |
Residual Variation Intolerance Score:
50.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
7.59;
82.56% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FCGR2B Gene
Disorders for FCGR2B Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| systemic lupus erythematosus |
|
|
| malaria |
|
|
| measles |
|
|
| cryptococcal meningitis |
|
|
| multifocal motor neuropathy |
|
|
Search FCGR2B in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
FCG2B_HUMAN- Systemic lupus erythematosus (SLE) [MIM:152700]: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow. {ECO:0000269 PubMed:12115230, ECO:0000269 PubMed:20385827}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
Relevant External Links for FCGR2B
No data available for Genatlas for FCGR2B Gene
Publications for FCGR2B Gene
- A defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus. (PMID: 20385827) Willcocks L.C. … Smith K.G. (Proc. Natl. Acad. Sci. U.S.A. 2010) 3 4 46 64
- Genetic susceptibility and haplotype analysis between Fcgamma receptor IIB and IIIA gene with systemic lupus erythematosus in Chinese population. (PMID: 18625651) Pan F. … Ye D.Q. (Lupus 2008) 3 22 46 64
- The combined genotypes of stimulatory and inhibitory Fc gamma receptors associated with systemic lupus erythematosus and periodontitis in Japanese adults. (PMID: 17335370) Kobayashi T. … Yoshie H. (J. Periodontol. 2007) 3 22 46 64
- Association of Fcgamma receptor IIB gene polymorphism with genetic susceptibility to systemic lupus erythematosus in Chinese populations--a family-based association study. (PMID: 16531013) Pan F. … Ye D. (J. Dermatol. Sci. 2006) 3 22 46 64
- The functional variant of the inhibitory Fcgamma receptor IIb (CD32B) is associated with the rate of radiologic joint damage and dendritic cell function in rheumatoid arthritis. (PMID: 17133580) Radstake T.R. … van Riel P.L. (Arthritis Rheum. 2006) 3 22 46 64
Products for FCGR2B Gene
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- GeneTex FCGR2B antibody for FCGR2B
- Search GeneTex for Proteins for FCGR2B
- Search ViGene Biosciences for FCGR2B
- Santa Cruz Biotechnology (SCBT) Antibodies for FCGR2B
- Search Santa Cruz Biotechnology (SCBT) for FCGR2B siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for FCGR2B
- Horizon Cell Lines for FCGR2B
- Cyagen custom Knockout/knockin (KOKI) mouse models for FCGR2B
- VectorBuilder custom plasmid, inducible vectors for FCGR2B
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FCGR2B
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FCGR2B Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer