Aliases for FCGR1B Gene
External Ids for FCGR1B Gene
Previous GeneCards Identifiers for FCGR1B Gene
Three distinct, but closely related classes of receptors that bind the Fc portion of IgG have been identified (Fcgamma RI, II and III). The FcgammaRI family consists of three closely related genes termed A, B, and C. This gene encodes the low affinity FcgammaRIB receptor that may play an important role in humoral immune response. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
GeneCards Summary for FCGR1B Gene
FCGR1B (Fc Fragment Of IgG Receptor Ib) is a Protein Coding gene. Among its related pathways are Interleukin-3, 5 and GM-CSF signaling and CDK-mediated phosphorylation and removal of Cdc6. GO annotations related to this gene include IgG binding and immunoglobulin receptor activity. An important paralog of this gene is FCGR1A.
UniProtKB/Swiss-Prot for FCGR1B Gene
May bind to the Fc region of immunoglobulins gamma with a low affinity compared to FCGR1A. May function in the humoral immune response.