Aliases for FCER2 Gene
External Ids for FCER2 Gene
Previous Symbols for FCER2 Gene
The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
GeneCards Summary for FCER2 Gene
FCER2 (Fc Fragment Of IgE, Low Affinity II, Receptor For (CD23)) is a Protein Coding gene. Diseases associated with FCER2 include chronic conjunctivitis and intrinsic asthma. Among its related pathways are Signaling by GPCR and GPCR Pathway. GO annotations related to this gene include carbohydrate binding and IgE binding. An important paralog of this gene is CLEC4D.
UniProtKB/Swiss-Prot for FCER2 Gene
Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen)