Aliases for FCER1G Gene
- Fc Fragment Of IgE, High Affinity I, Receptor For; Gamma Polypeptide 2 3
- Fc Receptor Gamma-Chain 3 4
- Fc-Epsilon RI-Gamma 3 4
- FceRI Gamma 3 4
- FcRgamma 3 4
- High Affinity Immunoglobulin Epsilon Receptor Subunit Gamma 3
- Immunoglobulin E Receptor, High Affinity, Gamma Chain 3
- IgE Fc Receptor Subunit Gamma 4
- FCRG 3
External Ids for FCER1G Gene
The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors. [provided by RefSeq, Jul 2008]
GeneCards Summary for FCER1G Gene
FCER1G (Fc Fragment Of IgE, High Affinity I, Receptor For; Gamma Polypeptide) is a Protein Coding gene. Diseases associated with FCER1G include aplastic anemia. Among its related pathways are PI-3K cascade and Akt Signaling. GO annotations related to this gene include IgG binding and IgE receptor activity.
UniProtKB/Swiss-Prot for FCER1G Gene
Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach the cell surface. Also involved in collagen-mediated platelet activation and in neutrophil activation mediated by integrin.