Aliases for FCER1G Gene
External Ids for FCER1G Gene
Previous GeneCards Identifiers for FCER1G Gene
The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors. [provided by RefSeq, Jul 2008]
GeneCards Summary for FCER1G Gene
FCER1G (Fc Fragment Of IgE Receptor Ig) is a Protein Coding gene. Among its related pathways are Cell surface interactions at the vascular wall and Response to elevated platelet cytosolic Ca2+. GO annotations related to this gene include transmembrane signaling receptor activity and IgE binding.
UniProtKB/Swiss-Prot for FCER1G Gene
Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach the cell surface. Also involved in collagen-mediated platelet activation and in neutrophil activation mediated by integrin.