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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

FCER1G Gene

protein-coding GIFtS: 60
GCID: GC01P161185

Fc fragment of IgE, high affinity I, receptor for; gamma...

Explore 9 diseases affiliated with
FCER1G via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Fc Fragment Of IgE, High Affinity I, Receptor For; Gamma Polypeptide¹ ²		FcRgamma³
Fc-Epsilon RI-Gamma² ³		High Affinity Immunoglobulin Epsilon Receptor Subunit Gamma²
FceRI Gamma² ³		Immunoglobulin E Receptor, High Affinity, Gamma Chain²
Fc Receptor Gamma-Chain² ³		FcRgamma³
FCRG²		IgE Fc Receptor Subunit Gamma³

External Ids:	HGNC: 3611¹	Entrez Gene: 2207²	Ensembl: ENSG00000158869⁷	OMIM: 147139⁵	UniProtKB: P30273³

Export aliases for FCER1G gene to outside databases

Previous GC identifers: GC01P158896 GC01P156917 GC01P157962 GC01P158402 GC01P158403 GC01P157998 GC01P159451 GC01P132542

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FCER1G:

The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha,

1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: FCERG_HUMAN, P30273

Function: Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several

aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach the

cell surface. Also involved in collagen-mediated platelet activation and in neutrophil activation mediated by integrin

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_004487.19

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the FCER1G gene promoter:
E2F-4 E2F-3a E2F-5 CUTL1 E2F-2 C/EBPalpha PPAR-gamma1 E2F E2F-1 PPAR-gamma2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: FCER1G promoter sequence

Search SABiosciences Chromatin IP Primers for FCER1G

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FCER1G

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q23 Ensembl cytogenetic band: 1q23.3 HGNC cytogenetic band: 1q23

FCER1G Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FCER1G gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P161185: view genomic region (about GC identifiers)

Start:	161,185,024 bp from pter	End:	161,190,489 bp from pter
Size:	5,466 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: FCERG_HUMAN, P30273 (See protein sequence)

Recommended Name: High affinity immunoglobulin epsilon receptor subunit gamma precursor

Size: 86 amino acids; 9667 Da

Subunit: IgE Fc receptor is a tetramer of an alpha chain, a beta chain, and two disulfide linked gamma chains. The

gamma chain from Fc-epsilon-Ri are also subunits of other Fc receptors like FCGR1A. Associated with CLEC6A (By

similarity). Interacts (via ITAM domain) with SYK (via SH2 domains); activates SYK, enabling integrin-mediated

activation of neutrophils and macrophages (By similarity). Interacts with CD300LH; the interaction may be indirect (By

similarity). Interacts with CD300LD (By similarity). Interacts with CLEC4E

Subcellular location: Cell membrane; Single-pass type I membrane protein

Secondary accessions: Q5VTW4

Explore the universe of human proteins at neXtProt for FCER1G: NX_P30273

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P30273

FCER1G Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_004097.1

ENSEMBL proteins:

ENSP00000356971 ENSP00000289902

Reactome Protein details: P30273
Human Recombinant Protein Products:

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	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Browse Proteins at Uscn

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	TAS	--
GO:0005887	integral to plasma membrane	IEA	--
GO:0009897	external side of plasma membrane	IEA	--
GO:0032998	Fc-epsilon receptor I complex	IEA	--

FCER1G for ontologies About GeneDecksing

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Assay Products for FCER1G:

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	Browse ELISAs and CLIAs at Uscn

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

FCER1G for domains About GeneDecksing

2 InterPro domains/families:

IPR003110 Phos_immunorcpt_sig_ITAM

IPR021663 CR3_zeta/IgE_Fc_rcpt_gamma

Graphical View of Domain Structure for InterPro Entry P30273

ProtoNet protein and cluster: P30273

1 Blocks protein family: IPB003110 Phosphorylated immunoreceptor signaling ITAM

UniProtKB/Swiss-Prot: FCERG_HUMAN, P30273

Similarity: Belongs to the CD3Z/FCER1G family

Similarity: Contains 1 ITAM domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: FCERG_HUMAN, P30273

Function: Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several

aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach the

cell surface. Also involved in collagen-mediated platelet activation and in neutrophil activation mediated by integrin

Genatlas biochemistry entry for FCER1G:

immunoglobulin E,high affinity Fc receptor,gamma polypeptide,expressed in most cells,homodimerizing

miRNA Products:		OriGene 3'-UTR Clone: FCER1G Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FCER1G
		1 QIAGEN miScript miRNA Assays for microRNA that regulate FCER1G:
		hsa-miR-4271
		SwitchGear 3'UTR luciferase reporter plasmid: FCER1G 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FCER1G (see all 7) OriGene shRNA RFP: FCER1G OriGene siRNA: FCER1G
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FCER1G

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for FCER1G

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		Search LifeMap BioReagents cell lines for FCER1G

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FCER1G

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	--	--
GO:0019767	IgE receptor activity	IEA	--
GO:0019863	IgE binding	IEA	--
GO:0019864	IgG binding	IEA	--

FCER1G for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for FCER1G:

Cell cycle / mitosis defect

Animal Models:
Mouse knock-outs for FCER1G: Fcer1g^tm1Tks Fcer1g^tm1Rav
15 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Fcer1g):

behavior/neurological	cardiovascular system	cellular	craniofacial	embryogenesis
growth/size	hematopoietic system	homeostasis/metabolism	immune system	limbs/digits/tail
mortality/aging	nervous system	renal/urinary system	reproductive system	skeleton

FCER1G for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/15 super-pathways (see all 15) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Immune response Fc epsilon RI pathway

	Immune response Fc epsilon RI pathway	1.00			Fc-epsilon receptor I signaling in mast cells	0.33
	Immune response_Fc epsilon RI pathway	0.99

Immune response_NFAT in immune response

Immune response_NFAT in immune response

1.00

Immune response NFAT in immune response

0.91

Platelet activation, signaling and aggregation

Platelet activation, signaling and aggregation

1.00

Hemostasis

0.43

GPVI-mediated activation cascade

GPVI-mediated activation cascade

1.00

GPVI stimulates PI3K beta, gamma

0.42

Phagocytosis of Microbes

Phagocytosis of Microbes

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

2 EMD Millipore Pathways for FCER1G

	Immune response NFAT in immune response
	Immune response Fc epsilon RI pathway

5 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for FCER1G

	NFAT Signaling and Lymphocyte Interactions
	Tec Kinases Signaling
	Fc-EpsilonRI Pathway
	NFAT in Immune Response
	Phagocytosis of Microbes

2 GeneGo (Thomson Reuters) Pathways for FCER1G

	Immune response Fc epsilon RI pathway
	Immune response NFAT in immune response

1 BioSystems Pathway for FCER1G

Fc-epsilon receptor I signaling in mast cells

5/6 Reactome Pathways for FCER1G (see all 6)

	Hemostasis
	Platelet Adhesion to exposed collagen
	Platelet activation, signaling and aggregation
	Cell surface interactions at the vascular wall
	GPVI stimulates PI3K beta, gamma

4 Kegg Pathways (Kegg details for FCER1G):

	Natural killer cell mediated cytotoxicity
	Fc epsilon RI signaling pathway
	Tuberculosis
	Asthma

FCER1G for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for FCER1G

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/54 Interacting proteins for FCER1G (P30273^{2, 3} ENSP00000289902⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 54)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SYK	P43405²^,³, ENSP00000364898⁴	MINT-8028449 I2D: score=6 STRING: ENSP00000364898
PLCG2	P16885³, ENSP00000352336⁴	I2D: score=3 STRING: ENSP00000352336
BTK	Q06187³, ENSP00000308176⁴	I2D: score=2 STRING: ENSP00000308176
FCGR3A	P08637³, ENSP00000356946⁴	I2D: score=2 STRING: ENSP00000356946
GP6	Q9HCN6³, ENSP00000308782⁴	I2D: score=2 STRING: ENSP00000308782

About this table

Gene Ontology (GO): 5/30 biological process terms (GO ID links to tree view) (see all 30): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001798	positive regulation of type IIa hypersensitivity	IEA	--
GO:0001805	positive regulation of type III hypersensitivity	IEA	--
GO:0001812	positive regulation of type I hypersensitivity	IEA	--
GO:0002283	neutrophil activation involved in immune response	IEA	--
GO:0002431	Fc receptor mediated stimulatory signaling pathway	IEA	--

FCER1G for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

FCER1G for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for FCER1G

1 DrugBank Compound for FCER1G About this table

Compound	Synonyms	CAS #	Type	Actions	PubMed Ids
Benzylpenicilloyl Polylysine	--	2642-55-9	target	agonist	7436456 17139284 11752352 17016423

1 Novoseek chemical compound relationship for FCER1G gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
tyrosine	7.39	1	8265641 (1)

Search CenterWatch for drugs/clinical trials and news about FCER1G / FCERG

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for FCER1G gene:

NM_004106.1

Unigene Cluster for FCER1G:

Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide

Hs.433300 [show with all ESTs]

Unigene Representative Sequence: BI909222

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000490414 ENST00000367992 ENST00000289902(uc001fyz.1 uc001fza.1)

miRNA Products:		OriGene 3'-UTR Clone: FCER1G Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FCER1G
		1 QIAGEN miScript miRNA Assays for microRNA that regulate FCER1G:
		hsa-miR-4271
		SwitchGear 3'UTR luciferase reporter plasmid: FCER1G 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Additional cDNA sequence:

AK307102.1 BC033872.1 M33195.1

4 DOTS entries:

DT.451781 DT.92424994 DT.95275345 DT.121463647

24/130 AceView cDNA sequences (see all 130):

CD364792 N98747 M33195 NM_004106 AA513769 AA699470 BU786848 AW951597

AI830761 BM662950 CA413064 R80909 AI127246 BM694296 BU789665 BM662934

R31350 N66119 CB529629 R79271 BX089542 BQ002398 BU786099 BX479412

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for FCER1G About this scheme

ExUns:	1a	·	1b	^	2	^	3
SP1:
SP2:

ECgene alternative splicing isoforms for FCER1G

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

FCER1G expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GACTGGAAAA

About this image

FCER1G expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

Mast-like cells (Generation of hemato...)

Posterior foregut-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See FCER1G Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FCER1G

SOURCE GeneReport for Unigene cluster: Hs.433300

SABiosciences Custom PCR Arrays for FCER1G

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FCER1G Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FCER1G

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FCER1G

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of human and mouse.

Orthologs for FCER1G gene from 1/6 species (see all 6) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Fcer1g^{1 , 5}	Fc receptor, IgE, high affinity I, gamma polypeptide^{1, 5}	88.37(n)¹ 88.37(a)¹		1 (79.23 cM)⁵ 14127¹ NM_010185.4¹ NP_034315.1¹ 171229572⁵

ENSEMBL Gene Tree for FCER1G (if available)
TreeFam Gene Tree for FCER1G (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs77823804^1,2	C,F,	--	132541160(+)	`NNNNCT/GTAGTG`	2	--	ds500¹		1		NA	120
rs6674857^1,2	C	--	132541575(+)	`agaaaC/Tcccat`	2	--	ds500¹		1		NA	2
rs36233990^1,2	C,	--	132541605(+)	`TTAGCC/TGGGCG`	2	--	ds500¹		0	--	--	--	--
rs12094497^1,2	C,F,H,	--	132543253(+)	`GCCAAG/AACAAA`	1	--	int¹		21		NS EA NA MN WA CSA	2452
rs11265566^1,2	F,H,	--	132544024(+)	`TAATAG/AGGCAG`	1	--	int¹		4		NS EA	416
rs75382076^1,2	F,	--	132544512(+)	`TTCAAT/CAGAAC`	1	--	int¹		1		WA	118
rs112079466^1,2		--	132545108(+)	`AGGGCC/ATGCCT`	1	--	int¹		2		CSA WA	120
rs74865766^1,2	F,	--	132545199(+)	`TGACAG/CGGAAG`	1	--	int¹		1		WA	118
rs11590967^1,2	C,F,A,H,	--	132545537(+)	`AGGCCG/AGTGGG`	1	--	int¹		5		NS EA NA	510
rs3557^1,2	C,F,A,H,	--	132545843(+)	`CCCTGT/GTAAAG`	1	--	ut3¹		36		MN NA NS EA WA CSA	3544

HapMap Linkage Disequilibrium report for FCER1G (161185024 - 161190489 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FCER1G: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FCER1G

DNA2.0 Custom Variant and Variant Library Synthesis for FCER1G

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

FCER1G for disorders           About GeneDecksing

OMIM gene information: 147139    OMIM disorders: --

9 diseases for FCER1G:    About MalaCards

nephrotic syndrome eczema urticaria hepatitis b

meningioma asthma hepatitis tuberculosis

leukemia

Genetic Association Database (GAD): FCER1G
Human Genome Epidemiology (HuGE) Navigator: FCER1G (15 documents)

Export disorders for FCER1G gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for FCER1G gene, integrated from 9 sources (see all 65):
(articles sorted by number of sources associating them with FCER1G)

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Characterization and expression of the gene for the human Fc receptor gamma subunit. Definition of a new gene family. (PubMed id 2138619)^{1, 2, 3} Kuester H.... Kinet J.-P. (1990)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{1, 2} Gregory S.G.... Bentley D.R. (2006)
Conservation of FcepsilonRI gamma chain coding region in normals and in SLE patients. (PubMed id 11898918)^{1, 4} Wu J....Kimberly R.P. (2002)
Type I IgE receptor, interleukin 4 receptor and interleukin 13 polymorphisms in children with nephrotic syndrome. (PubMed id 11980568)^{1, 4} Tenbrock K....Michalk D. (2002)
BDCA2/Fc epsilon RI gamma complex signals through a novel BCR-like pathway in human plasmacytoid dendritic cells. (PubMed id 17850179)^{1, 9} Cao W....Liu Y.J. (2007)
Expression feature of CD3, FceRIg, and Zap-70 in patie nts with chronic lymphocytic leukemia. (PubMed id 22664044)¹ Huang L....Li Y. (2012)
Demethylation of the FCER1G promoter leads to FceRI ov erexpression on monocytes of patients with atopic dermatitis. (PubMed id 22150093)¹ Liang Y....Lu Q. (2012)
Altered expression of the TCR signaling related genes CD3 and FceRIg in patients with aplastic anemia. (PubMed id 22401598)¹ Li B....Li Y. (2012)
CD2AP/SHIP1 complex positively regulates plasmacytoid dendritic cell receptor signaling by inhibiting the E3 ubiquitin ligase Cbl. (PubMed id 22706086)¹ Bao M....Liu Y.J. (2012)
A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (2011)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 2207	HGNC: 3611	AceView: FCER1G	Ensembl:ENSG00000158869	euGenes: HUgn2207
ECgene: FCER1G	Kegg: 2207	H-InvDB: FCER1G

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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Name	Description
PharmGKB entry for FCER1G	Pharmacogenomics, SNPs, Pathways

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