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FCER1G Gene

protein-coding   GIFtS: 64
GCID: GC01P161185

Fc Fragment Of IgE, High Affinity I, Receptor For; Gamma...

  See FCER1G-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Fc Fragment Of IgE, High Affinity I, Receptor For; Gamma
Polypeptide1 2
     fcRgamma2
Fc-Epsilon RI-Gamma2 3     High Affinity Immunoglobulin Epsilon Receptor Subunit Gamma2
FceRI Gamma2 3     Immunoglobulin E Receptor, High Affinity, Gamma Chain2
Fc Receptor Gamma-Chain2 3     FcRgamma3
FCRG2     IgE Fc Receptor Subunit Gamma3

External Ids:    HGNC: 36111   Entrez Gene: 22072   Ensembl: ENSG000001588697   OMIM: 1471395   UniProtKB: P302733   
ORGUL members:         

Export aliases for FCER1G gene to outside databases

Previous GC identifers: GC01P158896 GC01P156917 GC01P157962 GC01P158402 GC01P158403 GC01P157998 GC01P159451 GC01P132542


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for FCER1G Gene:
The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1
alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors. (provided by RefSeq,
Jul 2008)

GeneCards Summary for FCER1G Gene:
FCER1G (Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide) is a protein-coding gene. Diseases associated with FCER1G include aplastic anemia. GO annotations related to this gene include IgG binding and IgE receptor activity.

UniProtKB/Swiss-Prot: FCERG_HUMAN, P30273
Function: Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several
aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach
the cell surface. Also involved in collagen-mediated platelet activation and in neutrophil activation mediated by
integrin




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_004487.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the FCER1G gene promoter:
         E2F-4   E2F-3a   E2F-5   CUTL1   E2F-2   C/EBPalpha   PPAR-gamma1   E2F   E2F-1   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFCER1G promoter sequence
   Search Chromatin IP Primers for FCER1G

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FCER1G


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q23   Ensembl cytogenetic band:  1q23.3   HGNC cytogenetic band: 1q23

FCER1G Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FCER1G gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P161185:  view genomic region     (about GC identifiers)

Start:
161,185,024 bp from pter      End:
161,190,489 bp from pter
Size:
5,466 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: FCERG_HUMAN, P30273 (See protein sequence)
Recommended Name: High affinity immunoglobulin epsilon receptor subunit gamma precursor  
Size: 86 amino acids; 9667 Da
Subunit: IgE Fc receptor is a tetramer of an alpha chain, a beta chain, and two disulfide linked gamma chains. The
gamma chain from Fc-epsilon-Ri are also subunits of other Fc receptors like FCGR1A. Associated with CLEC6A (By
similarity). Interacts (via ITAM domain) with SYK (via SH2 domains); activates SYK, enabling integrin-mediated
activation of neutrophils and macrophages (By similarity). Interacts with CD300LH; the interaction may be
indirect (By similarity). Interacts with CD300LD (By similarity). Interacts with CLEC4E
Secondary accessions: Q5VTW4

Explore the universe of human proteins at neXtProt for FCER1G: NX_P30273

Explore proteomics data for FCER1G at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys60
  • Modification sites at PhosphoSitePlus

  • See FCER1G Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_004097.1  
    ENSEMBL proteins: 
     ENSP00000356971   ENSP00000289902  
    Reactome Protein details: P30273

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    antibodies-online proteins for FCER1G (2 products) 

     
    antibodies-online peptides for FCER1G

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR003110 Phos_immunorcpt_sig_ITAM
     IPR021663 CR3_zeta/IgE_Fc_rcpt_gamma

    Graphical View of Domain Structure for InterPro Entry P30273

    ProtoNet protein and cluster: P30273

    1 Blocks protein domain: IPB003110 Phosphorylated immunoreceptor signaling ITAM

    UniProtKB/Swiss-Prot: FCERG_HUMAN, P30273
    Similarity: Belongs to the CD3Z/FCER1G family
    Similarity: Contains 1 ITAM domain


    Find genes that share domains with FCER1G           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FCERG_HUMAN, P30273
    Function: Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several
    aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach
    the cell surface. Also involved in collagen-mediated platelet activation and in neutrophil activation mediated by
    integrin

         Genatlas biochemistry entry for FCER1G:
    immunoglobulin E,high affinity Fc receptor,gamma polypeptide,expressed in most cells,homodimerizing

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004888transmembrane signaling receptor activity ----
    GO:0005515protein binding IPI8810294
    GO:0019767IgE receptor activity IEA--
    GO:0019863IgE binding IEA--
    GO:0019864IgG binding IEA--
         
    Find genes that share ontologies with FCER1G           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for FCER1G:
     Cell cycle / mitosis defect 

         15 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Fcer1g):
     behavior/neurological  cardiovascular system  cellular  craniofacial  embryogenesis 
     growth/size/body  hematopoietic system  homeostasis/metabolism  immune system  limbs/digits/tail 
     mortality/aging  nervous system  renal/urinary system  reproductive system  skeleton 

    Find genes that share phenotypes with FCER1G           About GenesLikeMe

    Animal Models:
         MGI mouse knock-outs for FCER1G: Fcer1gtm1Tks Fcer1gtm1Rav

       genOway: Develop your customized and physiologically relevant rodent model for FCER1G

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    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    FCERG_HUMAN, P30273: Cell membrane; Single-pass type I membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    extracellular2
    endoplasmic reticulum1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0005887integral component of plasma membrane IEA--
    GO:0009897external side of plasma membrane IEA--
    GO:0009986cell surface IDA1535625
    GO:0016020membrane ----

    Find genes that share ontologies with FCER1G           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for FCER1G About   (see all 16)  
    See pathways by source

    SuperPathContained pathways About
    1Immune response Fc epsilon RI pathway
    Immune response Fc epsilon RI pathway0.43
    Fc-epsilon receptor I signaling in mast cells0.34
    Fc epsilon RI signaling pathway0.41
    2Hemostasis
    Hemostasis0.43
    Platelet activation, signaling and aggregation0.43
    3PI-3K cascade
    Fc epsilon receptor (FCERI) signaling0.64
    4GPCR Pathway
    NFAT in Immune Response0.58
    5PEDF Induced Signaling
    NFAT Signaling and Lymphocyte Interactions0.57


    Find genes that share SuperPaths with FCER1G           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 R&D Systems Pathway for FCER1G
        Pathogen or Damage-activated C-Type Lectin Receptor Signaling Pathways

    5 Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for FCER1G
        NFAT Signaling and Lymphocyte Interactions
    Tec Kinases Signaling
    Fc-EpsilonRI Pathway
    NFAT in Immune Response
    Phagocytosis of Microbes

    2 GeneGo (Thomson Reuters) Pathways for FCER1G
        Immune response Fc epsilon RI pathway
    Immune response NFAT in immune response

    1 BioSystems Pathway for FCER1G
        Fc-epsilon receptor I signaling in mast cells


    Selected Reactome Pathways for FCER1G (see all 8)
        Platelet Adhesion to exposed collagen
    FCERI mediated MAPK activation
    FCERI mediated NF-kB activation
    Role of LAT2/NTAL/LAB on calcium mobilization
    GPVI-mediated activation cascade


    4 Kegg Pathways  (Kegg details for FCER1G):
        Natural killer cell mediated cytotoxicity
    Fc epsilon RI signaling pathway
    Tuberculosis
    Asthma

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FCER1G
    Interactions:

        Search GeneGlobe Interaction Network for FCER1G

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for FCER1G (P302731, 2, 3 ENSP000002899024) via UniProtKB, MINT, STRING, and/or I2D (see all 54)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SYKP434051, 2, 3, ENSP000003648984EBI-515289,EBI-78302 MINT-8028449 I2D: score=6 STRING: ENSP00000364898
    PLCG2P168853, ENSP000003523364I2D: score=3 STRING: ENSP00000352336
    BTKQ061873, ENSP000003081764I2D: score=2 STRING: ENSP00000308176
    FCGR3AP086373, ENSP000003569464I2D: score=2 STRING: ENSP00000356946
    GP6Q9HCN63, ENSP000003087824I2D: score=2 STRING: ENSP00000308782
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 31):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001798positive regulation of type IIa hypersensitivity IEA--
    GO:0001805positive regulation of type III hypersensitivity IEA--
    GO:0001812positive regulation of type I hypersensitivity IEA--
    GO:0002283neutrophil activation involved in immune response IEA--
    GO:0002431Fc receptor mediated stimulatory signaling pathway IEA--

    Find genes that share ontologies with FCER1G           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FCER1G (FCERG)

    1 DrugBank Compound for FCER1G    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Benzylpenicilloyl Polylysine-- 2642-55-9targetagonist7436456 17139284 11752352 17016423

    1 Novoseek inferred chemical compound relationship for FCER1G gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tyrosine 7.39 1 8265641 (1)

    1 PharmGKB related drug/compound annotation for FCER1G gene    About this table
    Drug/compound PharmGKB Annotation
    aspirinCA  



    Find genes that share compounds with FCER1G           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for FCER1G gene: 
    NM_004106.1  

    Unigene Cluster for FCER1G:

    Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
    Hs.433300  [show with all ESTs]
    Unigene Representative Sequence: BI909222
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000490414 ENST00000367992 ENST00000289902(uc001fyz.1 uc001fza.1)

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    Additional mRNA sequence: 

    AK307102.1 BC033872.1 M33195.1 

    4 DOTS entries:

    DT.451781  DT.92424994  DT.95275345  DT.121463647 

    Selected AceView cDNA sequences (see all 130):

    NM_004106 BM662950 AI127246 M33195 AI830761 AA699470 BM694296 CD364792 
    AA513769 BU786848 R80909 N98747 AW951597 CA413064 AI310689 R79271 
    BX479412 CD641483 AI292115 CD640349 BX089542 BC033872 BQ002398 BU786099 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for FCER1G    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3
    SP1:                        
    SP2:                        


    ECgene alternative splicing isoforms for FCER1G

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FCER1G expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GACTGGAAAA
    FCER1G Expression
    About this image


    FCER1G expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 12) fully expand
     
     Brain (Nervous System)    fully expand to see all 5 entries
             Cerebral Cortex
     
     Spleen (Hematopoietic System)
             Conventional Dendritic Cells II Spleen
     
     Epithelial Cells
             Adult Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
     
     NULL (Uncategorized)
             Mast-like cells
     
     Bone (Muscoskeletal System)
             Bone Marrow
    FCER1G Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FCER1G Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.433300
        Custom PCR Arrays for FCER1G
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for FCER1G gene from Selected species (see all 6)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fcer1g1 , 5 Fc receptor, IgE, high affinity I, gamma polypeptide1, 5 89.05(n)1
    89.55(a)1
      1 (79.23 cM)5
    141271  NM_010185.41  NP_034315.11 
     1712295725 


    ENSEMBL Gene Tree for FCER1G (if available)
    TreeFam Gene Tree for FCER1G (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FCER1G gene
    Selected SIMAP similar genes for FCER1G using alignment to 2 protein entries:     FCERG_HUMAN (see all proteins) (see all similar genes):
    DYNC2LI1    RRM2B    EEF1E1    MRPL45    UTY    FAM3A
    ZNF66    ADCK1    TFR2    ZNF799    ADRA1A    RAD51
    CCDC122    CD247    NLRC5    SNRPF    SH2B3    SUN3

    Find genes that share paralogs with FCER1G           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FCER1G (see all 120)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs710903691,2
    C--132543163(-) CTATA-/CT/TA 
            
    TATAT
    1 -- int11NA 2
    rs1509570271,2
    --161184763(+) TTGCAC/TTCCAG 1 -- us2k10--------
    rs1886922491,2
    --161184842(+) GGAAAA/TTGGCA 1 -- us2k10--------
    rs115872131,2
    C,F,A,H--161184875(+) CGTGAA/GAGTCT 1 -- us2k130Minor allele frequency- N:0.00EA NA NS MN CSA 3257
    rs1917565471,2
    --161184909(+) GGTCAC/TTGAAG 1 -- us2k10--------
    rs412708471,2
    C--161184976(+) CGCCCA/GGTCTC 1 -- us2k10--------
    rs1838797881,2
    --161185037(+) GAGGGA/GGACTC 1 -- us2k10--------
    rs20709011,2
    C,F,O,A--161185058(+) GAACTG/TCTCGC 1 -- us2k116Minor allele frequency- N:0.00EA NA NS WA CSA 2494
    rs1132208671,2
    C--161185096(+) ACGGCG/CGATCT 1 -- ut511Minor allele frequency- C:0.50CSA 2
    rs1128392851,2
    C--161185097(+) CGGCCA/GATCTC 1 -- ut511Minor allele frequency- G:0.00CSA 1

    HapMap Linkage Disequilibrium report for FCER1G (161185024 - 161190489 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for FCER1G:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv482136CNV Loss20164927

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FCER1G
    DNA2.0 Custom Variant and Variant Library Synthesis for FCER1G

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 147139    OMIM disorders: --

    1 disease for FCER1G:    
    About MalaCards
    aplastic anemia


    Find genes that share disorders with FCER1G           About GenesLikeMe

    Genetic Association Database (GAD): FCER1G
    Human Genome Epidemiology (HuGE) Navigator: FCER1G (15 documents)

    Export disorders for FCER1G gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FCER1G gene, integrated from 10 sources (see all 68):
    (articles sorted by number of sources associating them with FCER1G)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization and expression of the gene for the human Fc receptor gamma subunit. Definition of a new gene family. (PubMed id 2138619)1, 2, 3 Kuester H.... Kinet J.-P. (J. Biol. Chem. 1990)
    2. Risk of meningioma and common variation in genes related to innate immunity. (PubMed id 20406964)1, 4 Rajaraman P....Inskip P.D. (amp 2010)
    3. Polymorphisms in innate immunity genes and risk of childhood leukemia. (PubMed id 20438785)1, 4 Han S....Kang D. (Hum. Immunol. 2010)
    4. Analysis of the high affinity IgE receptor genes reveals epistatic effects of FCER1A variants on eczema risk. (PubMed id 20028371)1, 4 Mahachie John J.M....Weidinger S. (Allergy 2010)
    5. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    6. Analysis of high-affinity IgE receptor (FcepsilonR1) polymorphisms in patients with aspirin-intolerant chronic urticaria. (PubMed id 18534082)1, 4 Palikhe N....Park H.S. (Allergy Asthma Proc 2008)
    7. Association and functional relevance of E237G, a polymorphism of the high-affinity immunoglobulin E-receptor beta chain gene, to airway hyper-responsiveness. (PubMed id 17430357)1, 4 Kim Y.K....Kim Y.Y. (Clin. Exp. Allergy 2007)
    8. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    9. Conservation of FcepsilonRI gamma chain coding region in normals and in SLE patients. (PubMed id 11898918)1, 4 Wu J....Kimberly R.P. (Lupus 2002)
    10. Type I IgE receptor, interleukin 4 receptor and interleukin 13 polymorphisms in children with nephrotic syndrome. (PubMed id 11980568)1, 4 Tenbrock K....Michalk D. (Clin. Sci. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 2207 HGNC: 3611 AceView: FCER1G Ensembl:ENSG00000158869 euGenes: HUgn2207
    ECgene: FCER1G Kegg: 2207 H-InvDB: FCER1G

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for FCER1G Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for FCER1G gene:
    Search GeneIP for patents involving FCER1G

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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