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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FCAR Gene

protein-coding   GIFtS: 61
GCID: GC19P055386

Fc fragment of IgA, receptor for

 Explore 24 diseases affiliated with
FCAR via our new
 Human Malady Compendium 
Biological research products
for FCAR
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Fc Fragment Of IgA, Receptor For1 2
CD891 2 3
IgA Fc Receptor2 3
Fc Alpha Receptor2
Immunoglobulin Alpha Fc Receptor2
CD89 Antigen3

External Ids:    HGNC: 36081   Entrez Gene: 22042   Ensembl: ENSG000001864317   OMIM: 1470455   UniProtKB: P240713   

Export aliases for FCAR gene to outside databases

Previous GC identifers: GC19P056248 GC19P055810 GC19P060006 GC19P060077 GC19P051708


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FCAR:
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The
receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils,
monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with
IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent
cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced
transcript variants encoding different isoforms have been described for this gene. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: FCAR_HUMAN, P24071
Function: Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production

Gene Wiki entry for FCAR


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011109.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FCAR gene promoter:
         CREB   RORalpha1   deltaCREB   NF-kappaB1   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFCAR promoter sequence
   Search SABiosciences Chromatin IP Primers for FCAR

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FCAR


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.42   Ensembl cytogenetic band:  19q13.42   HGNC cytogenetic band: 19q13.42

FCAR Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FCAR gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P055386:  view genomic region     (about GC identifiers)

Start:
55,385,549 bp from pter      End:
55,401,839 bp from pter
Size:
16,291 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: FCAR_HUMAN, P24071 (See protein sequence)
Recommended Name: Immunoglobulin alpha Fc receptor precursor  
Size: 287 amino acids; 32265 Da
Subunit: Associates with the Fc epsilon RI gamma 2 receptor inducing tyrosine phosphorylation of gamma 2
Subcellular location: Isoform A.1: Cell membrane; Single-pass type I membrane protein
Subcellular location: Isoform A.2: Cell membrane; Single-pass type I membrane protein
Subcellular location: Isoform A.3: Cell membrane; Single-pass type I membrane protein
Subcellular location: Isoform B: Secreted
Subcellular location: Isoform B-delta-S2: Secreted
3 PDB 3D structures from and Proteopedia for FCAR:
1OVZ (3D)        1OW0 (3D)        1UCT (3D)    
Secondary accessions: Q13603 Q13604 Q15727 Q15728 Q1AJL7 Q1AJL8 Q1AJL9 Q53X38 Q53X39 Q92587 Q92588
Q92590 Q92592 Q92593 Q9UEK0
Alternative splicing: 11 isoforms:  P24071-1   P24071-2   P24071-3   P24071-4   P24071-5   P24071-6   P24071-7   P24071-8   
P24071-9   P24071-10   P24071-11   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for FCAR: NX_P24071

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P24071

  • FCAR Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (9 alternative transcripts): 
    NP_001991.1  NP_579803.1  NP_579805.1  NP_579806.1  NP_579807.1  NP_579808.1  NP_579811.1  NP_579812.1  
    NP_579813.1  

    ENSEMBL proteins: 
     ENSP00000375606   ENSP00000347714   ENSP00000375605   ENSP00000338257   ENSP00000338058  
     ENSP00000352218   ENSP00000375603   ENSP00000375604   ENSP00000403072  

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    Novus Biologicals FCAR Proteins
    Novus Biologicals FCAR Lysates
    Sino Biological Recombinant Protein for FCAR
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for FCAR

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0005886plasma membrane IDA--
    GO:0005887integral to plasma membrane TAS2258698
    GO:0016021integral to membrane ----


    FCAR for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    FCAR for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR013783 Ig-like_fold
     IPR003599 Ig_sub

    Graphical View of Domain Structure for InterPro Entry P24071

    ProtoNet protein and cluster: P24071

    1 Blocks protein family: IPB003599 Immunoglobulin subtype

    UniProtKB/Swiss-Prot: FCAR_HUMAN, P24071
    Similarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: FCAR_HUMAN, P24071
    Function: Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production

         Genatlas biochemistry entry for FCAR:
    immunoglobulin A,Fc receptor expressed on granulocyte,monocyte,macrophage,T cell,B cell,complexing with a cytoplasmic
    homodimer gamma subunit with the immunoreceptor based inhibitory motif (ITIM),natural killer inhibitory receptor
    family

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    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FCAR

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004872receptor activity ----
    GO:0019862IgA binding IEA--


    FCAR for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Staphylococcus aureus infection
    Staphylococcus aureus infection1.00
    2Phagosome
    Phagosome1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways



    2         Kegg Pathways  (Kegg details for FCAR):
        Phagosome
    Staphylococcus aureus infection


    FCAR for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for FCAR

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/10 Interacting proteins for FCAR (P240713 ENSP000003477144) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CD79AP119123, ENSP000002219724I2D: score=1 STRING: ENSP00000221972
    PILRAQ9UKJ13, ENSP000001985364I2D: score=1 STRING: ENSP00000198536
    IGHA1P018763, ENSP000003749894I2D: score=1 STRING: ENSP00000374989
    FCGR1AP123143, ENSP000003581654I2D: score=2 STRING: ENSP00000358165
    OSCARQ8IYS53, ENSP000003526714I2D: score=1 STRING: ENSP00000352671
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006955immune response TAS10835685


    FCAR for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    FCAR for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FCAR
    5 Novoseek chemical compound relationships for FCAR gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tyrosine 28.4 6 9234476 (1), 9427690 (1), 8626653 (1), 9581809 (1) (see all 5)
    mannose 5.4 2 11751952 (1), 8262556 (1)
    oxygen 4.27 1 10477741 (1)
    superoxide 0 1 8014525 (1)
    serine 0 2 11369640 (1), 12023895 (1)

    Search CenterWatch for drugs/clinical trials and news about FCAR 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FCAR gene (10 alternative transcripts): 
    NM_002000.2  NM_133269.2  NM_133271.2  NM_133272.2  NM_133273.2  NM_133274.2  NM_133277.2  NM_133278.2  
    NM_133279.2  NM_133280.1  

    Unigene Cluster for FCAR:

    Fc fragment of IgA, receptor for
    Hs.659872  [show with all ESTs]
    Unigene Representative Sequence: NM_002000
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000391726 ENST00000469767 ENST00000488066 ENST00000472634 ENST00000355524(uc002qhr.1 uc002qhs.1 uc002qht.1 uc010esi.1 uc002qhu.1 uc002qhv.1 uc002qhw.1 uc002qhx.1 uc002qhy.1 uc002qhz.1 uc002qia.1)
    ENST00000391725 ENST00000345937 ENST00000353758 ENST00000359272 ENST00000391723
    ENST00000391724 ENST00000482092 ENST00000471750 ENST00000433231(uc021vbp.1 uc002qhq.3)


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    Inhib. RNA
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    Additional cDNA sequence: 

    AK290922.1 BC027953.1 D87853.1 D87854.1 D87855.1 D87856.1 D87857.1 D87858.1 
    D87859.1 D87860.1 D87861.1 D87862.1 DQ075334.1 DQ075335.1 DQ075336.1 DQ075337.1 
    DQ075338.1 DQ075339.1 S82919.1 U43677.1 U43774.1 U56236.1 U56237.1 X90753.1 
    X92558.1 X92559.1 X92560.1 X92561.1 X92562.1 

    11 DOTS entries:

    DT.451562  DT.92421597  DT.100024013  DT.451561  DT.100781093  DT.92476477  DT.100781094  DT.92421596 
    DT.92421598  DT.86840917  DT.121419885 

    24/45 AceView cDNA sequences (see all 45):

    U43774 BF894027 BI518718 X90753 D87862 D87856 U43677 NM_133280 
    D87854 NM_133278 NM_133272 BI029218 D87855 NM_002000 NM_133274 NM_133273 
    D87861 D87853 NM_133269 NM_133271 D87857 NM_133277 X92561 D87858 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for FCAR (see all 9)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b · 4c · 4d ^ 5a · 5b · 5c
    SP1:              -                             -                     
    SP2:              -                 -     -     -                     
    SP3:              -                       -     -                     
    SP4:                                      -     -                     
    SP5:                                            -                     


    ECgene alternative splicing isoforms for FCAR

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FCAR expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTCAAACCAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See FCAR Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FCAR

    SOURCE GeneReport for Unigene cluster: Hs.659872

    UniProtKB/Swiss-Prot: FCAR_HUMAN, P24071
    Tissue specificity: Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal
    myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are
    expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces

        SABiosciences Expression via Pathway-Focused PCR Array including FCAR: 
              HIV Host Response in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FCAR

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for FCAR gene from 2/7 species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves --
    --
    (see all 59)
    --
    24(a)
    23(a)
    (see all 59)
    many ↔ many
    many ↔ many
    (see all 59)
    Un(51843257-51844123)
    Un(10797126-10797984)
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 3)
    --
    9(a)
    18(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    GL343329.1(1200149-1218701)
    GL343329.1(1231914-1234163)


    ENSEMBL Gene Tree for FCAR (if available)
    TreeFam Gene Tree for FCAR (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FCAR gene
    KIR2DL42  LILRB42  LILRB12  LILRA62  IGSF12  LILRA52  KIR3DL12  OSCAR2  
    NCR12  LILRA42  ENSG000002177922  TARM12  KIR3DX12  LILRA32  LILRB52  LILRA12  
    KIR3DL32  KIR2DL12  LILRB22  A1BG2  KIR2DL22  LILRA22  KIR3DL22  KIR2DL32  
    LILRB32  GP62  
    5 SIMAP similar genes for FCAR using alignment to 3 protein entries:     FCAR_HUMAN (see all proteins):
    GP6    LILRA4    TARM1    LILRA2    LILRA5

    FCAR for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/474 NCBI SNPs in FCAR are shown (see all 474    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1465802161,2
    C,other55386805(+) CAGAGA/C/GATTCA 17 R S int1 syn1 mis11NA 4552
    rs1382425921,2
    --55383618(+) AGTAGA/TGACTG 9 -- us2k10--------
    rs1812643871,2
    --55383777(+) TCTCTA/GCATTT 9 -- us2k10--------
    rs177719791,2
    C,F,H,--55383907(+) AATGCG/AGTCAA 9 -- us2k19Minor allele frequency- A:0.04NA NS EA 802
    rs116659861,2
    C,F,H,--55383941(+) ATTTCC/TAGAAC 9 -- us2k126Minor allele frequency- T:0.26NA NS EA WA 2898
    rs1867213231,2
    --55383970(+) CCGAAA/CGTAAA 9 -- us2k10--------
    rs177815561,2
    C,F,H,--55383977(+) TAAATA/GTGTAT 9 -- us2k110Minor allele frequency- G:0.06NA NS EA WA 920
    rs1914983541,2
    --55384108(+) TCGGCA/GTTGGA 9 -- us2k10--------
    rs1835609891,2
    --55384157(+) GGGCGA/CGGTGG 9 -- us2k10--------
    rs116660551,2
    C,F,H,--55384167(+) GCTCAT/CGCCTG 9 -- us2k14Minor allele frequency- C:0.43NA CSA 7

    HapMap Linkage Disequilibrium report for FCAR (55385549 - 55401839 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 5 variations for FCAR
         5 CNVs: 4088 53237 0809 2248 3200
    Human Gene Mutation Database (HGMD): FCAR

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    FCAR for disorders           About GeneDecksing

    OMIM gene information: 147045    OMIM disorders: --

    20/24 diseases for FCAR (see all 24):    About MalaCards
    lichen planus    oral lichen planus    berger disease    iga glomerulonephritis
    ankylosing spondylitis    spondylitis    aggressive periodontitis    allergic asthma
    myocardial infarction    spondyloarthropathy    glomerulonephritis    asthma
    rheumatoid arthritis    multiple sclerosis    periodontitis    hepatitis c
    nephropathy    hepatitis b    alcoholism    gingivitis

    8 Novoseek disease relationships for FCAR gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    nephropathy iga 80.4 11 10344348 (1), 7538927 (1), 9573548 (1), 11776381 (1) (see all 9)
    alcoholic cirrhosis 47.3 1 7636220 (1)
    asthma allergic 12.9 4 15564774 (3)
    spondylitis ankylosing 11.5 4 10685807 (2)
    virus infection 0 1 17033823 (1)
    necrosis 0 3 2010162 (1), 8014525 (1), 12560105 (1)
    tumors 0 11 9469424 (1), 9373259 (1), 12393717 (1), 15843545 (1) (see all 10)
    lymphoma 0 1 20042573 (1)

    Genetic Association Database (GAD): FCAR
    Human Genome Epidemiology (HuGE) Navigator: FCAR (14 documents)

    Export disorders for FCAR gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FCAR gene, integrated from 9 sources (see all 177):
    (articles sorted by number of sources associating them with FCAR)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Are single nucleotide polymorphisms of the immunoglobulin A Fc receptor gene associated with allergic asthma? (PubMed id 15564774)1, 4, 9 Jasek M....Kusnierczyk P. (2004)
    2. IgA nephropathy-specific expression of the IgA Fc receptors (CD89) on blood phagocytic cells. (PubMed id 9367406)1, 2, 9 Toyabe S.... Abo T. (1997)
    3. Identification of Fc alpha receptor (CD89) isoforms generated by alternative splicing that are differentially expressed between blood monocytes and alveolar macrophages. (PubMed id 8666819)1, 2, 9 Patry C.... Monteiro R.C. (1996)
    4. Structure of the gene for the human myeloid IgA Fc receptor (CD89). (PubMed id 7636188)1, 2, 9 de Wit T.P.M.... van de Winkel J.G.J. (1995)
    5. Crystal structure of the ectodomain of human FcalphaRI. (PubMed id 12783876)1, 2, 9 Ding Y....Rao Z. (2003)
    6. Association of IgA-Fc receptors (Fc alpha R) with Fc epsilon RI gamma 2 subunits in U937 cells. Aggregation induces the tyrosine phosphorylation of gamma 2. (PubMed id 7522255)1, 2, 9 Pfefferkorn L.C. and Yeaman G.R. (1994)
    7. The gene for the human IgA Fc receptor maps to 19q13.4. (PubMed id 1577457)1, 3, 9 Kremer E.J....Maliszewski C.R. (1992)
    8. Episodes of natural selection shaped the interactions of IgA-Fc with FcalphaRI and bacterial decoy proteins. (PubMed id 17548632)1, 2 Abi-Rached L.... Parham P. (2007)
    9. An unappreciated role for RNA surveillance. (PubMed id 14759258)1, 2 Hillman R.T.... Brenner S.E. (2004)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 2204 HGNC: 3608 AceView: FCAR Ensembl:ENSG00000186431 euGenes: HUgn2204
    ECgene: FCAR Kegg: 2204 H-InvDB: FCAR

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FCAR Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for FCAR gene:
    Search GeneIP for patents involving FCAR

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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