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Aliases for FBXW4P1 Gene

Aliases for FBXW4P1 Gene

  • F-Box And WD Repeat Domain Containing 4 Pseudogene 1 2 3 5
  • Split Hand/Foot Malformation (Ectrodactyly) Type 3 Pseudogene 1 2 3
  • F-Box And WD-40 Domain Protein 3 2 3
  • SHFM3P1 3
  • FBXW3 3
  • FBW3 3

External Ids for FBXW4P1 Gene

Previous HGNC Symbols for FBXW4P1 Gene

  • FBXW3
  • SHFM3P1

Previous GeneCards Identifiers for FBXW4P1 Gene

  • GC22P021934
  • GC22P023604
  • GC22P006572

Summaries for FBXW4P1 Gene

GeneCards Summary for FBXW4P1 Gene

FBXW4P1 (F-Box And WD Repeat Domain Containing 4 Pseudogene 1) is a Pseudogene. Diseases associated with FBXW4P1 include Split Hand Foot Malformation.

Gene Wiki entry for FBXW4P1 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FBXW4P1 Gene

Genomics for FBXW4P1 Gene

Regulatory Elements for FBXW4P1 Gene

Enhancers for FBXW4P1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH22F023240 1.3 Ensembl ENCODE 22.7 -16.5 -16521 12.5 ARID4B ZNF2 BRCA1 ZNF48 GLIS2 ZNF143 ZNF548 FOS ZNF263 SP5 IGLV5-52 FBXW4P1 ENSG00000272779 ZNF70 RAB36 ENSG00000234630 RSPH14 ENSG00000272578 ENSG00000232545 BCR
GH22F023278 1.6 FANTOM5 Ensembl ENCODE 13.5 +18.3 18279 5.8 HDGF ATF1 PKNOX1 CREB3L1 ARID4B YBX1 ZNF48 ZNF2 GLIS2 ZNF143 ZNF70 RAB36 FBXW4P1 RSPH14 IGLV5-52 ENSG00000272779 BCR PIR39869 GC22P023342
GH22F023269 0.8 ENCODE 13.8 +7.1 7074 1.4 CTCF ESRRA CBX3 USF1 TBL1XR1 BACH1 ZNF316 POLR2A SMC3 NFE2 FBXW4P1 RAB36 RSPH14 PIR39869 GC22P023342
GH22F023289 0.9 ENCODE 12.2 +27.2 27228 1.5 ELF3 HDGF PKNOX1 ARID4B RAD21 RARA ZNF143 KLF13 ZHX1 ZNF263 FBXW4P1 RAB36 RSPH14 BCR GC22P023342 PIR39869
GH22F023256 0.9 Ensembl ENCODE 11.4 -5.7 -5711 1.7 BCOR KLF1 TBL1XR1 ZMYM3 RAD21 NR2F2 YY1 ZFP3 HNF4G E2F6 FBXW4P1 RAB36 RN7SL263P BCRP8
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around FBXW4P1 on UCSC Golden Path with GeneCards custom track

Genomic Location for FBXW4P1 Gene

Chromosome:
22
Start:
23,262,767 bp from pter
End:
23,265,005 bp from pter
Size:
2,239 bases
Orientation:
Plus strand

Genomic View for FBXW4P1 Gene

Genes around FBXW4P1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FBXW4P1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FBXW4P1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FBXW4P1 Gene

Proteins for FBXW4P1 Gene

Post-translational modifications for FBXW4P1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for FBXW4P1 Gene

Domains & Families for FBXW4P1 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for FBXW4P1 Gene

Function for FBXW4P1 Gene

genes like me logo Genes that share phenotypes with FBXW4P1: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FBXW4P1 Gene

Localization for FBXW4P1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FBXW4P1 Gene

Pathways & Interactions for FBXW4P1 Gene

SuperPathways for FBXW4P1 Gene

No Data Available

Interacting Proteins for FBXW4P1 Gene

Gene Ontology (GO) - Biological Process for FBXW4P1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FBXW4P1 Gene

Transcripts for FBXW4P1 Gene

mRNA/cDNA for FBXW4P1 Gene

(4) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FBXW4P1 Gene

F-box and WD repeat domain containing 4 pseudogene 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FBXW4P1 Gene

No ASD Table

Relevant External Links for FBXW4P1 Gene

GeneLoc Exon Structure for
FBXW4P1
ECgene alternative splicing isoforms for
FBXW4P1

Expression for FBXW4P1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for FBXW4P1 Gene

NURSA nuclear receptor signaling pathways regulating expression of FBXW4P1 Gene:

FBXW4P1

SOURCE GeneReport for Unigene cluster for FBXW4P1 Gene:

Hs.729589
genes like me logo Genes that share expression patterns with FBXW4P1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for FBXW4P1 Gene

Orthologs for FBXW4P1 Gene

Evolution for FBXW4P1 Gene

ENSEMBL:
Gene Tree for FBXW4P1 (if available)
TreeFam:
Gene Tree for FBXW4P1 (if available)

No data available for Orthologs for FBXW4P1 Gene

Paralogs for FBXW4P1 Gene

No data available for Paralogs for FBXW4P1 Gene

Variants for FBXW4P1 Gene

Sequence variations from dbSNP and Humsavar for FBXW4P1 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs1054814 -- 23,264,870(+) ACCAA(A/G)AGAGG intron-variant, nc-transcript-variant
rs1054815 -- 23,264,896(+) CAGTT(C/T)TGAGT intron-variant, nc-transcript-variant
rs112251748 -- 23,264,966(+) GTAAA(A/T)ATAAA intron-variant, nc-transcript-variant
rs113157063 -- 23,264,257(+) ACGTC(A/C/G)ACCCG intron-variant, nc-transcript-variant
rs113558787 -- 23,264,793(+) GCCAG(A/T)CCTCA intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for FBXW4P1 Gene

Variant ID Type Subtype PubMed ID
esv2762117 CNV gain 21179565
esv3647392 CNV gain 21293372
esv3647395 CNV gain 21293372
nsv9876 CNV gain+loss 18304495
nsv7350 OTHER inversion 18451855
nsv588598 CNV loss 21841781
nsv588512 CNV loss 21841781
nsv521695 CNV loss 19592680
nsv1066891 CNV gain 25217958
nsv1061433 CNV gain+loss 25217958
nsv1059951 CNV gain 25217958
esv3893457 CNV gain 25118596

Relevant External Links for FBXW4P1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FBXW4P1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for FBXW4P1 Gene

Disorders for FBXW4P1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for FBXW4P1 Gene - From: GeneCards

Disorder Aliases PubMed IDs
split hand foot malformation
  • ectrodactyly
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for FBXW4P1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FBXW4P1
genes like me logo Genes that share disorders with FBXW4P1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for FBXW4P1 Gene

Publications for FBXW4P1 Gene

  1. Identification of a family of human F-box proteins. (PMID: 10531035) Cenciarelli C. … Pagano M. (Curr. Biol. 1999) 2 3 64
  2. A family of mammalian F-box proteins. (PMID: 10531037) Winston J.T. … Harper J.W. (Curr. Biol. 1999) 2 3 64
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64
  4. M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP. (PMID: 15070733) Watanabe N. … Osada H. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 64
  5. A novel human gene encoding an F-box/WD40 containing protein maps in the SHFM3 critical region on 10q24. (PMID: 10405324) Ianakiev P. … Tsipouras P. (Biochem. Biophys. Res. Commun. 1999) 3 64

Products for FBXW4P1 Gene

Sources for FBXW4P1 Gene

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