Aliases for FBXW11 Gene
Aliases for FBXW11 Gene
External Ids for FBXW11 Gene
- HGNC: 13607
- Entrez Gene: 23291
- Ensembl: ENSG00000072803
- OMIM: 605651
- UniProtKB: Q9UKB1
Previous HGNC Symbols for FBXW11 Gene
- FBXW1B
Previous GeneCards Identifiers for FBXW11 Gene
- GC05M171270
- GC05M171221
- GC05M166384
- GC05M171288
Summaries for FBXW11 Gene
-
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq, Jul 2008]
GeneCards Summary for FBXW11 Gene
FBXW11 (F-Box And WD Repeat Domain Containing 11) is a Protein Coding gene. Among its related pathways are IL-1 signaling pathway and Activated TLR4 signalling. GO annotations related to this gene include ubiquitin-protein transferase activity and protein dimerization activity. An important paralog of this gene is BTRC.
UniProtKB/Swiss-Prot for FBXW11 Gene
-
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. SCF(FBXW11) mediates the ubiquitination of phosphorylated CTNNB1 and participates in Wnt signaling. SCF(FBXW11) mediates the ubiquitination of phosphorylated NFKBIA, which degradation frees the associated NFKB1 to translocate into the nucleus and to activate transcription. SCF(FBXW11) mediates the ubiquitination of IFNAR1. SCF(FBXW11) mediates the ubiquitination of CEP68; this is required for centriole separation during mitosis (PubMed:25503564). Involved in the oxidative stress-induced a ubiquitin-mediated decrease in RCAN1. Mediates the degradation of CDC25A induced by ionizing radiation in cells progressing through S phase and thus may function in the intra-S-phase checkpoint. Has an essential role in the control of the clock-dependent transcription via degradation of phosphorylated PER1 and phosphorylated PER2. Is target of human immunodeficiency virus type 1 (HIV-1) protein VPU to polyubiquitinate and deplete BST2 from cells and antagonize its antiviral action.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FBXW11 Gene
Genomics for FBXW11 Gene
Regulatory Elements for FBXW11 Gene
Enhancers for FBXW11 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH05G172004 | 1.8 | FANTOM5 ENCODE dbSUPER | 0.7 | -0.5 | -489 | 5.7 | HDGF PKNOX1 FOXA2 MLX CREB3L1 ARNT ZFP64 WRNIP1 ARID4B SIN3A | STK10 UBTD2 FBXW11 GC05P172013 |
| GH05G172002 | 1 | ENCODE dbSUPER | 0.7 | +3.6 | 3602 | 0.6 | GTF2E2 ZMYM3 BMI1 FOSL1 ZFHX2 ARID3A ZNF366 NFYB PRDM10 IKZF2 | FBXW11 GC05P171872 |
| GH05G172003 | 0.7 | ENCODE dbSUPER | 0.7 | +3.0 | 2982 | 0.2 | FOS PRDM1 | FBXW11 GC05P171872 |
| GH05G171999 | 1.2 | Ensembl ENCODE dbSUPER | 0.4 | +7.1 | 7073 | 1.3 | BCOR BHLHE40 ZMYM3 MAX JUNB TBX21 PRDM6 IKZF1 ZKSCAN8 KDM1A | FBXW11 GC05P171872 |
| GH05G171988 | 1.1 | ENCODE dbSUPER | 0.4 | +17.1 | 17071 | 1.6 | TBL1XR1 BACH1 BMI1 RELA ZNF664 ZFHX2 ARID3A ZNF366 CBX5 EED | FBXW11 GC05P171872 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FBXW11 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the FBXW11 gene promoter:
Regulatory Element Products
Genomic Location for FBXW11 Gene
- Chromosome:
- 5
- Start:
- 171,861,549 bp from pter
- End:
- 172,006,873 bp from pter
- Size:
- 145,325 bases
- Orientation:
- Minus strand
Genomic View for FBXW11 Gene
Genes around FBXW11 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 5q35.1 by Ensembl
- 5q35.1 by Entrez Gene
- 5q35.1 by HGNC
FBXW11 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FBXW11 Gene
Proteins for FBXW11 Gene
-
Protein details for FBXW11 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9UKB1-FBW1B_HUMAN
- Recommended name:
- F-box/WD repeat-containing protein 11
- Protein Accession:
- Q9UKB1
- B2RC98
- Q9P2S8
- Q9P2S9
- Q9Y4C6
Protein attributes for FBXW11 Gene
- Size:
- 542 amino acids
- Molecular mass:
- 62091 Da
- Quaternary structure:
-
- Self-associates. Component of the SCF(FBXW11) complex formed of CUL1, SKP1, RBX1 and a FBXW11 dimer. Interacts with BTRC, BST2, PER1, RCAN1 and USP47. Interacts with phosphorylated ubiquitination substrates CTNNB1, NFKBIA, IFNAR1, PER1 and PER2; the interaction requires the phosphorylation of the two serine residues in the substrates destruction motif D-S-G-X(2,3,4)-S. Interacts with TRIM21. Interacts with PER3. Interacts with phosphorylated ubiquitination substrate CEP68 (PubMed:25503564).
- SequenceCaution:
-
- Sequence=BAA31671.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
Protein Expression for FBXW11 Gene
Post-translational modifications for FBXW11 Gene
Other Protein References for FBXW11 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
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-
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Protein Products
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- antibodies-online Proteins for FBXW11: See all 4
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Assay Products
- antibodies-online Kits for FBXW11: See all 15
No data available for DME Specific Peptides for FBXW11 Gene
Domains & Families for FBXW11 Gene
Gene Families for FBXW11 Gene
Protein Domains for FBXW11 Gene
Suggested Antigen Peptide Sequences for FBXW11 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9UKB1- Domain:
-
- The N-terminal D domain mediates homodimerization.
Function for FBXW11 Gene
Molecular function for FBXW11 Gene
- UniProtKB/Swiss-Prot Function:
- Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. SCF(FBXW11) mediates the ubiquitination of phosphorylated CTNNB1 and participates in Wnt signaling. SCF(FBXW11) mediates the ubiquitination of phosphorylated NFKBIA, which degradation frees the associated NFKB1 to translocate into the nucleus and to activate transcription. SCF(FBXW11) mediates the ubiquitination of IFNAR1. SCF(FBXW11) mediates the ubiquitination of CEP68; this is required for centriole separation during mitosis (PubMed:25503564). Involved in the oxidative stress-induced a ubiquitin-mediated decrease in RCAN1. Mediates the degradation of CDC25A induced by ionizing radiation in cells progressing through S phase and thus may function in the intra-S-phase checkpoint. Has an essential role in the control of the clock-dependent transcription via degradation of phosphorylated PER1 and phosphorylated PER2. Is target of human immunodeficiency virus type 1 (HIV-1) protein VPU to polyubiquitinate and deplete BST2 from cells and antagonize its antiviral action.
- UniProtKB/Swiss-Prot Induction:
- Expression is negatively regulated by Wnt/beta-catenin pathway.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004842 | ubiquitin-protein transferase activity | TAS | -- |
| GO:0005515 | protein binding | IPI | 12482991 |
| GO:0046983 | protein dimerization activity | IEA | -- |
| GO:0061630 | ubiquitin protein ligase activity | IEA | -- |
Phenotypes for FBXW11 Gene
- MGI mutant phenotypes for FBXW11:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for FBXW11:
-
- Increased vaccinia virus (VACV) infection
- Increased gamma-H2AX phosphorylation
- Decreased viability
- shRNA abundance <= 50%
- Synthetic lethal with Ras
- Increased shRNA abundance (Z-score > 2)
- Decreased shRNA abundance (Z-score < -2)
- Decreased p24 protein expression
- Increased transferrin (TF) endocytosis
- Increased G1 DNA content
- G0/1 arrest
- Increased cell death HMECs cells
- Synthetic lethal with vaccinia virus (VACV) infection
- Increased circadian period length
- Downregulation of Wnt pathway after Wnt3A stimulation
- Decreased viability of wild-type and TP53 knockout cells
- Decreased Tat-dependent transcription
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miRNA for FBXW11 Gene
- miRTarBase miRNAs that target FBXW11
-
- hsa-mir-148b-3p (MIRT019282)
- hsa-mir-450a-5p (MIRT042396)
- hsa-mir-16-5p (MIRT051087)
- hsa-mir-192-3p (MIRT358381)
- hsa-mir-6892-5p (MIRT442258)
- hsa-mir-6878-5p (MIRT442259)
- hsa-mir-504-3p (MIRT442260)
- hsa-mir-5703 (MIRT442261)
- hsa-mir-4516 (MIRT442262)
- hsa-mir-4434 (MIRT442263)
- hsa-mir-1909-5p (MIRT442264)
- hsa-mir-6770-5p (MIRT442265)
- hsa-mir-6760-5p (MIRT442266)
- hsa-mir-4475 (MIRT442267)
- hsa-mir-4433b-3p (MIRT442268)
miRNA Products
- Search ViGene Biosciences for FBXW11
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-
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Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FBXW11 Gene
Localization for FBXW11 Gene
Subcellular locations from UniProtKB/Swiss-Prot for FBXW11 Gene
- Cytoplasm. Nucleus.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| nucleus | 5 |
| cytosol | 5 |
| peroxisome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000151 | ubiquitin ligase complex | NAS | 10531035 |
| GO:0005634 | nucleus | ISS | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005813 | centrosome | IDA | 21399614 |
| GO:0005829 | cytosol | TAS | -- |
Pathways & Interactions for FBXW11 Gene
Pathways by source for FBXW11 Gene
7 BioSystems pathways for FBXW11 Gene
44 Reactome pathways for FBXW11 Gene
7 KEGG pathways for FBXW11 Gene
5 GeneGo (Thomson Reuters) pathways for FBXW11 Gene
Interacting Proteins for FBXW11 Gene
Selected Interacting proteins:
ENSP00000265094
Q9UKB1-FBW1B_HUMAN
for FBXW11 Gene via
STRING
MINT
IID
UniProtKB
SIGNOR curated interactions for FBXW11 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000086 | G2/M transition of mitotic cell cycle | TAS | -- |
| GO:0000209 | protein polyubiquitination | TAS | -- |
| GO:0002223 | stimulatory C-type lectin receptor signaling pathway | TAS | -- |
| GO:0006470 | protein dephosphorylation | ISS | -- |
| GO:0007049 | cell cycle | IEA | -- |
Transcripts for FBXW11 Gene
mRNA/cDNA for FBXW11 Gene
- (10) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (209) Selected AceView cDNA sequences:
- (12) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FBXW11 Gene
CRISPR Products
-
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-
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miRNA Products
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-
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Clone Products
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Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - |
Expression for FBXW11 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
This gene is overexpressed in Peripheral blood mononuclear cells (30.6), Retina (21.0), and Testis (7.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for FBXW11 Gene
NURSA nuclear receptor signaling pathways regulating expression of FBXW11 Gene:
FBXW11SOURCE GeneReport for Unigene cluster for FBXW11 Gene:
Hs.484138Evidence on tissue expression from TISSUES for FBXW11 Gene
- Nervous system(4.8)
- Lung(4.3)
Primer Products
-
OriGene qPCR primer pairs for FBXW11
-
OriGene qPCR primer pairs and template standards for FBXW11
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FBXW11 Gene
Orthologs for FBXW11 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FBXW11 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | FBXW11 34 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | FBXW11 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | FBXW11 35 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | FBXW11 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Fbxw11 34 16 35 |
|
||
| chicken (Gallus gallus) |
Aves | FBXW11 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | FBXW11 35 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | fbxw11a 35 |
|
OneToMany | |
| fbxw11b 34 35 |
|
||||
| fbxw1b 34 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | slmb 35 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | lin-23 34 35 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | MET30 35 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.8954 35 |
|
OneToMany |
- Species where no ortholog for FBXW11 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Paralogs for FBXW11 Gene
Paralogs for FBXW11 Gene
(6) SIMAP similar genes for FBXW11 Gene using alignment to 5 proteins:
Pseudogenes.org Pseudogenes for FBXW11 Gene
Variants for FBXW11 Gene
| SNP ID | Clin | Chr 05 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000055208 | -- | 171,886,576(+) | ATAAA(A/C)AATAA | intron-variant | |
| rs1000056226 | -- | 171,982,355(+) | ACCTC(C/T)GCCTC | intron-variant | |
| rs1000073028 | -- | 171,921,444(+) | TGTTC(C/T)ACTCA | intron-variant | |
| rs1000108282 | -- | 171,982,567(+) | CAGAA(C/G)GGCTA | intron-variant | |
| rs1000149477 | -- | 171,895,604(+) | CTCAA(A/C)TGGCA | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2762568 | CNV | loss | 21179565 |
| esv3326841 | CNV | insertion | 20981092 |
| esv3607585 | CNV | loss | 21293372 |
| nsv1020999 | CNV | gain | 25217958 |
| nsv328032 | CNV | deletion | 16902084 |
Residual Variation Intolerance Score:
15% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.40;
8.85% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FBXW11 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FBXW11 Gene
Disorders for FBXW11 Gene
Relevant External Links for FBXW11
No disorders were found for FBXW11 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FBXW11 Gene
Publications for FBXW11 Gene
- Molecular cloning and genomic structure of the betaTRCP2 gene on chromosome 5q35.1. (PMID: 10694485) Koike J. … Katoh M. (Biochem. Biophys. Res. Commun. 2000) 2 3 4 64
- Identification of a family of human F-box proteins. (PMID: 10531035) Cenciarelli C. … Pagano M. (Curr. Biol. 1999) 2 3 4 64
- HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkappaB and beta-catenin. (PMID: 10321728) Fuchs S.Y. … Ronai Z. (Oncogene 1999) 3 4 22 64
- The ubiquitin-specific protease USP47 is a novel beta-TRCP interactor regulating cell survival. (PMID: 19966869) Peschiaroli A. … Melino G. (Oncogene 2010) 3 4 64
- Priming and extending: a UbcH5/Cdc34 E2 handoff mechanism for polyubiquitination on a SCF substrate. (PMID: 20347421) Wu K. … Pan Z.Q. (Mol. Cell 2010) 3 4 64
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- Yeast expression
Sources for FBXW11 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer