FBXO8 Gene
protein-coding GIFtS: 47
GCID: GC04M175157
|
|
F-box protein 8(Previous name: F-box only protein 8 )
| |
Aliases
for FBXO8 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| F-Box Protein 81 2 | | FBS1 2 3 5 | | FBX81 2 3 5 | | F-Box Only Protein 81 2 | | F-Box/SEC7 Protein FBS2 3 | | F-Box Protein Fbx82 |
Export aliases for FBXO8 gene to outside databasesPrevious GC identifers: GC04M176077 GC04M175695 GC04M175742 GC04M175853 GC04M175532 GC04M175394 GC04M170904 |
Summaries
for FBXO8 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for FBXO8:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif,the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs(SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either differentprotein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxsclass. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p,a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylationfactor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: FBX8_HUMAN, Q9NRD0Function: May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDPwith GTP (Potential)
|
Genomic Views
for FBXO8 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_016354.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FBXO8 gene promoter:
NCX/Ncx HTF LUN-1 Cdc5 MZF-1 AREB6 RORalpha1 POU2F1 POU2F1a Pax-4a
Other transcription factors
Search SABiosciences Chromatin IP Primers for FBXO8
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FBXO8 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q34.1 Ensembl cytogenetic band: 4q34.1 HGNC cytogenetic band: 4q34.1FBXO8 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04M175157: view genomic region
(about GC identifiers)
Start:
|
175,157,809 bp from pter |
End:
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175,205,415 bp from pter |
Size:
|
47,607 bases |
Orientation:
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minus strand |
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Proteins
for FBXO8 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: FBX8_HUMAN, Q9NRD0 (See
protein sequence)Recommended Name: F-box only protein 8 Size: 319 amino acids; 37068 Da
Sequence caution: Sequence=AAF04517.1; Type=Erroneous initiation;
Secondary accessions: B2RB40 D3DP41 Q6UWN4 Q9NRP5 Q9UKC4Explore the universe of human proteins at neXtProt for FBXO8: NX_Q9NRD0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NRD0
FBXO8 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_036312.2
ENSEMBL proteins: ENSP00000377280 ENSP00000422905 ENSP00000427313 ENSP00000427506
Human Recombinant Protein Products for FBXO8:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
FBXO8 for ontologies About GeneDecksing
FBXO8 Antibody Products:
Assay Products for FBXO8: |
Protein
Domains /
Families
for FBXO8 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FBXO8 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9NRD0ProtoNet protein and cluster: Q9NRD0 1 Blocks protein family: IPB000904 SEC7-like domain
UniProtKB/Swiss-Prot: FBX8_HUMAN, Q9NRD0Similarity: Contains 1 F-box domainSimilarity: Contains 1 SEC7 domain |
Function
for FBXO8 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: FBX8_HUMAN, Q9NRD0Function: May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDPwith GTP (Potential) Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005086 | ARF guanyl-nucleotide exchange factor activity |
NAS | -- |
FBXO8 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FBXO8 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FBXO8 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector: FBXO8 (NM_012180) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FBXO8 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FBXO8 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FBXO8 |
|
Pathways & Interactions
for FBXO8 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Arf6 signaling events | |
1  BioSystems Pathway for FBXO8
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FBXO8
STRING Interaction
Network Preview (showing 5 interactants - click image to see 6)
5/6 Interacting proteins for FBXO8 (Q9NRD03 ENSP000003772804) via UniProtKB, MINT, STRING, and/or I2D (see all 6)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006511 | ubiquitin-dependent protein catabolic process |
NAS | 10945468 | | GO:0016192 | NOT vesicle-mediated transport |
IBA | -- | | GO:0030036 | actin cytoskeleton organization |
IBA | -- | | GO:0032012 | regulation of ARF protein signal transduction |
IEA | -- |
FBXO8 for ontologies About GeneDecksing
|
Drugs & Compounds
for FBXO8 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FBXO8
1 HMDB Compound for FBXO8 About this table
Search CenterWatch for drugs/clinical trials and news about FBXO8 / FBX8
|
Transcripts
for FBXO8 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FBXO8 gene: NM_012180.2 Unigene Cluster for FBXO8: F-box protein 8 Hs.76917 [show with all ESTs]Unigene Representative Sequence: NM_0121804 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000393674(uc003itp.3 uc003itq.3) ENST00000503293 ENST00000515664
ENST00000513696
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FBXO8 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FBXO8 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FBXO8 (NM_012180) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FBXO8 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FBXO8 |
Additional cDNA sequence: AF115514.1 AF174596.1 AF201932.1 AF233224.1 AK026319.1 AK123740.1 AK314483.1 AY358721.1 BC014679.2 BC014903.1 BC040456.1 7 DOTS entries: DT.453294 DT.100793143 DT.100766227 DT.95200782 DT.100028146 DT.121271481 DT.92439080 24/217 AceView cDNA sequences (see all 217): BG200344 AL543285 CR617381 AI472064 CK904242 CR603561 BF001727 BI225297 AW261927 CK904243 BM979219 BX460164 CD108902 CB156073 BC014679 CR621638 CA418592 BI827173 AK026319 NM_012180 BI791572 CR592920 AA933777 AY358721
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for FBXO8 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | |
ECgene alternative splicing isoforms for FBXO8
|
Expression
for FBXO8 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FBXO8 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See FBXO8 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FBXO8
SOURCE GeneReport for Unigene cluster: Hs.76917
SABiosciences Custom PCR Arrays for FBXO8
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FBXO8
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FBXO8 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FBXO8 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FBXO8 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FBXO8 |
Orthologs
for FBXO8 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for FBXO8 gene from 5/20 species (see all 20) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
FBXO81 |
F-box protein 8 |
86.42(n)
95.92(a) |
|
422565 NM_001006446.1 NP_001006446.1 |
lizard
(Anolis carolinensis) |
Reptilia |
FBXO86 |
-- |
94(a) |
1 ↔ 1 |
3(144007660-144019767) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.186502 |
Xenopus laevis transcribed sequence with strong similarity more |
82.61(n) |
|
BI443365.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
fbxo81 |
F-box protein 8 |
70.13(n)
80.82(a) |
|
678549 NM_001040307.1 NP_001035397.1 |
rice
(Oryza sativa) |
Liliopsida |
-- |
guanine nucleotide exchange family protein, putati... |
|
1 → many |
6(25049896-25054632) |
ENSEMBL Gene Tree for FBXO8 (if available)
TreeFam Gene Tree for FBXO8 (if available) |
Paralogs
for FBXO8 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FBXO8 gene
- PSD32 GBF12 CYTH32 IQSEC32 CYTH22 ARFGEF22 PSD42 ARFGEF12
- IQSEC12 PSD22 PSD2 IQSEC22 CYTH42 CYTH12
2 SIMAP similar genes for FBXO8 using alignment to 6 protein entries: FBX8_HUMAN (see all proteins):MST051 FBXO11
FBXO8 for paralogs About GeneDecksing
|
Genomic Variants
for FBXO8 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 4 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FBXO8 (175157809 - 175205415 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FBXO8: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FBXO8 |
|
Disorders
/ Diseases
for FBXO8 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 FBXO8 for disorders About MalaCards
FBXO8 for disorders About GeneDecksing
OMIM gene information: 605649
OMIM disorders: --
Human Genome Epidemiology (HuGE) Navigator: FBXO8 (1 document)
Export disorders for FBXO8 gene to outside databases
|
Publications
for FBXO8 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FBXO8 gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with FBXO8) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of a family of human F-box proteins. (PubMed id 10531035)1, 2, 3 Cenciarelli C....Pagano M. (1999)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- cDNA cloning and expression analysis of new members of the mammalian F-box protein family. (PubMed id 10945468)1, 2 Ilyin G.P.... Guguen-Guillouzo C. (2000)
- A family of mammalian F-box proteins. (PubMed id 10531037)1, 3 Winston J.T....Harper J.W. (1999)
- c-Myc stimulates cell invasion by inhibiting FBX8 fun ction. (PubMed id 20848231)1 Cho H.J....Kim H. (2010)
- Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
- Fbx8 makes Arf6 refractory to function via ubiquitination. (PubMed id 18094045)1 Yano H....Sabe H. (2008)
- Screening for replication of genome-wide SNP associations in sporadic ALS. (PubMed id 18987618)1 Cronin S....Hardiman O. (2008)
|
External Searches for FBXO8 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FBXO8 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FBXO8 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FBXO8 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FBXO8 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FBXO8 gene:
Search GeneIP for patents involving FBXO8
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FBXO8 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
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| |
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| | | | Search Tocris compounds for FBXO8 |
| |  |  |  |  | | | | |
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 |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FBXO8 |
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