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Aliases for FBXO48 Gene

Aliases for FBXO48 Gene

  • F-Box Protein 48 2 3
  • FBX48 4

External Ids for FBXO48 Gene

Summaries for FBXO48 Gene

GeneCards Summary for FBXO48 Gene

FBXO48 (F-Box Protein 48) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FBXO48 Gene

Genomics for FBXO48 Gene

Genomic Location for FBXO48 Gene

Start:
68,459,419 bp from pter
End:
68,467,316 bp from pter
Size:
7,898 bases
Orientation:
Minus strand

Genomic View for FBXO48 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FBXO48 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FBXO48 Gene

Regulatory Elements for FBXO48 Gene

Proteins for FBXO48 Gene

  • Protein details for FBXO48 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5FWF7-FBX48_HUMAN
    Recommended name:
    F-box only protein 48
    Protein Accession:
    Q5FWF7
    Secondary Accessions:

    Protein attributes for FBXO48 Gene

    Size:
    155 amino acids
    Molecular mass:
    18241 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FBXO48 Gene

Proteomics data for FBXO48 Gene at MOPED

Post-translational modifications for FBXO48 Gene

No Post-translational modifications

Other Protein References for FBXO48 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FBXO48 Gene

Domains for FBXO48 Gene

Gene Families for FBXO48 Gene

HGNC:
  • FBXO :F-boxes / "other"

Protein Domains for FBXO48 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

FBX48_HUMAN
Domain:
  • Contains 1 F-box domain.:
    • Q5FWF7
genes like me logo Genes that share domains with FBXO48: view

Function for FBXO48 Gene

Gene Ontology (GO) - Molecular Function for FBXO48 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with FBXO48: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FBXO48 Gene

Localization for FBXO48 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FBXO48 Gene COMPARTMENTS Subcellular localization image for FBXO48 gene
Compartment Confidence
extracellular 2
nucleus 2
cytosol 1
mitochondrion 1

No data available for Gene Ontology (GO) - Cellular Components for FBXO48 Gene

Pathways for FBXO48 Gene

SuperPathways for FBXO48 Gene

No Data Available

Interacting Proteins for FBXO48 Gene

Gene Ontology (GO) - Biological Process for FBXO48 Gene

None

No data available for Pathways by source for FBXO48 Gene

Transcripts for FBXO48 Gene

mRNA/cDNA for FBXO48 Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FBXO48 Gene

F-box protein 48:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FBXO48 Gene

No ASD Table

Relevant External Links for FBXO48 Gene

GeneLoc Exon Structure for
FBXO48
ECgene alternative splicing isoforms for
FBXO48

Expression for FBXO48 Gene

mRNA expression in normal human tissues for FBXO48 Gene

SOURCE GeneReport for Unigene cluster for FBXO48 Gene Hs.164117

genes like me logo Genes that share expressions with FBXO48: view

Orthologs for FBXO48 Gene

This gene was present in the common ancestor of chordates.

Orthologs for FBXO48 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FBXO48 36
  • 99.35 (n)
  • 98.71 (a)
FBXO48 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FBXO48 36
  • 89.25 (n)
  • 86.45 (a)
FBXO48 37
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FBXO48 36
  • 90.11 (n)
  • 85.81 (a)
FBXO48 37
  • 64 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fbxo48 36
  • 81.94 (n)
  • 75.48 (a)
Fbxo48 16
Fbxo48 37
  • 73 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FBXO48 37
  • 68 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FBXO48 37
  • 59 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fbxo48 36
  • 78.65 (n)
  • 70.59 (a)
chicken
(Gallus gallus)
Aves FBXO48 36
  • 64.07 (n)
  • 57.79 (a)
FBXO48 37
  • 58 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FBXO48 37
  • 67 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii FBXO48 37
  • 52 (a)
OneToOne
LOC100537883 36
  • 59.47 (n)
  • 59.2 (a)
Species with no ortholog for FBXO48:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FBXO48 Gene

ENSEMBL:
Gene Tree for FBXO48 (if available)
TreeFam:
Gene Tree for FBXO48 (if available)

Paralogs for FBXO48 Gene

No data available for Paralogs for FBXO48 Gene

Variants for FBXO48 Gene

Sequence variations from dbSNP and Humsavar for FBXO48 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs7419812 -- 68,465,493(+) cgatt(C/T)tcttg intron-variant
rs12614904 - 68,465,099(+) CTTCT(A/G)TGTGA reference, missense
rs35477253 -- 68,465,495(+) ATTCT(C/T)TTGAC intron-variant
rs36078393 -- 68,464,243(+) CCCCC(-/C)ATGTA reference, frameshift-variant
rs62146965 -- 68,465,518(+) GCCCC(A/T)CTTTA intron-variant

Relevant External Links for FBXO48 Gene

HapMap Linkage Disequilibrium report
FBXO48

No data available for Structural Variations from Database of Genomic Variants (DGV) for FBXO48 Gene

Disorders for FBXO48 Gene

No disorders were found for FBXO48 Gene.

No data available for UniProtKB/Swiss-Prot for FBXO48 Gene

Publications for FBXO48 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. (PMID: 22190364) Patsopoulos N.A. … de Bakker P.I. (Ann. Neurol. 2011) 3
  3. Genetic analysis of the FBXO48 gene in Chinese Han patients with Parkinson disease. (PMID: 23485738) Xiu X. … Deng H. (Neurosci. Lett. 2013) 3
  4. Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein. (PMID: 23898208) Johnson T.P. … Nath A. (Proc. Natl. Acad. Sci. U.S.A. 2013) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for FBXO48 Gene

Sources for FBXO48 Gene

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