Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

FBXO34 Gene

protein-coding GIFtS: 46
GCID: GC14P055738

F-box protein 34

(Previous name: F-box only protein 34 )

Search for FBXO34
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
F-Box Protein 34¹ ²
Fbx34¹ ²
F-Box Only Protein 34¹ ²
FBX34³ ⁵
FLJ20725¹
Protein CGI-301²

External Ids:	HGNC: 20201¹	Entrez Gene: 55030²	Ensembl: ENSG00000178974⁷	OMIM: 609104⁵	UniProtKB: Q9NWN3³

Export aliases for FBXO34 gene to outside databases

Previous GC identifers: GC14P049534 GC14P053728 GC14P054807 GC14P035900

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FBXO34:

Members of the F-box protein family, such as FBXO34, are characterized by an approximately 40-amino acid F-box motif.

SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as

protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination

targets through other protein interaction domains (Jin et al., 2004 (PubMed 15520277)).(supplied by OMIM, Mar 2008)

UniProtKB/Swiss-Prot: FBX34_HUMAN, Q9NWN3

Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex (By

similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000014.8 NC_018925.1 NT_026437.12

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the FBXO34 gene promoter:
HOXA9B HOXA9 Arnt Meis-1 Meis-1b
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: FBXO34 promoter sequence

Search SABiosciences Chromatin IP Primers for FBXO34

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FBXO34

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q22.3 Ensembl cytogenetic band: 14q22.3 HGNC cytogenetic band: 14q22.1

FBXO34 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FBXO34 gene location

GeneLoc information about chromosome 14 GeneLoc Exon Structure

GeneLoc location for GC14P055738: view genomic region (about GC identifiers)

Start:	55,738,021 bp from pter	End:	55,828,636 bp from pter
Size:	90,616 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: FBX34_HUMAN, Q9NWN3 (See protein sequence)

Recommended Name: F-box only protein 34

Size: 711 amino acids; 78711 Da

Subunit: Directly interacts with SKP1 and CUL1 (By similarity)

Sequence caution: Sequence=BAA91346.1; Type=Erroneous initiation; Sequence=CAD62596.1; Type=Erroneous initiation;

Secondary accessions: Q2VPB5 Q86TY4

Explore the universe of human proteins at neXtProt for FBXO34: NX_Q9NWN3

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9NWN3

FBXO34 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_060413.2 NP_689417.1

ENSEMBL proteins:

ENSP00000313159 ENSP00000450877 ENSP00000394117

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells Browse OriGene Protein Over-expression Lysates OriGene Custom Protein Services for FBXO34
	GenScript Custom Purified and Recombinant Proteins Services for FBXO34
	Novus Biologicals FBXO34 Proteins Novus Biologicals FBXO34 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for FBXO34

FBXO34 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for FBXO34
	GenScript Custom Superior Antibodies Services for FBXO34
	Novus Biologicals FBXO34 Antibodies
	Search for Antibodies for FBXO34 at Abcam
	Uscn Antibodies for FBXO34
	ThermoFisher Antibody for FBXO34

Assay Products for FBXO34:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for FBXO34
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for FBXO34

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

FBXO34 for domains About GeneDecksing

1 InterPro domain/family:

IPR001810 F-box_dom_cyclin-like

Graphical View of Domain Structure for InterPro Entry Q9NWN3

ProtoNet protein and cluster: Q9NWN3

UniProtKB/Swiss-Prot: FBX34_HUMAN, Q9NWN3

Similarity: Contains 1 F-box domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: FBX34_HUMAN, Q9NWN3

Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex (By

similarity)

miRNA Products:		OriGene 3'-UTR Clone (see all 2): FBXO34 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FBXO34
		8/41 QIAGEN miScript miRNA Assays for microRNAs that regulate FBXO34 (see all 41):
		hsa-miR-3607-3p hsa-miR-411 hsa-miR-3651 hsa-let-7a-2* hsa-miR-30d hsa-miR-342-3p hsa-miR-570 hsa-miR-30a

		SwitchGear 3'UTR luciferase reporter plasmid: FBXO34 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FBXO34 (see all 7) OriGene shRNA RFP: FBXO34 OriGene siRNA: FBXO34
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FBXO34

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for FBXO34

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FBXO34 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FBXO34 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): FBXO34 (NM_152231)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for FBXO34
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FBXO34

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for FBXO34
		Search LifeMap BioReagents cell lines for FBXO34

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FBXO34

1 GenomeRNAi human phenotype for FBXO34:

Increased cell death HMECs cel

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for FBXO34

STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

3 Interacting proteins for FBXO34 (Q9NWN3^{2, 3} ENSP00000313159⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SKP1	P63208²^,³, ENSP00000231487⁴	MINT-63990 I2D: score=4 STRING: ENSP00000231487
TGFBR1	P36897³, ENSP00000364133⁴	I2D: score=3 STRING: ENSP00000364133
SMAD4	Q13485³, ENSP00000341551⁴	I2D: score=3 STRING: ENSP00000341551

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for FBXO34
Search CenterWatch for drugs/clinical trials and news about FBXO34 / FBX34

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for FBXO34 gene (2 alternative transcripts):

NM_017943.3 NM_152231.1

Unigene Cluster for FBXO34:

F-box protein 34

Hs.525348 [show with all ESTs]

Unigene Representative Sequence: NM_017943

7 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000313833(uc001xbu.3 uc010aoo.3) ENST00000554940 ENST00000555087

ENST00000557647 ENST00000556920 ENST00000555280(uc001xbv.3) ENST00000440021

miRNA Products:		OriGene 3'-UTR Clone (see all 2): FBXO34 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FBXO34
		8/41 QIAGEN miScript miRNA Assays for microRNAs that regulate FBXO34 (see all 41):
		hsa-miR-3607-3p hsa-miR-411 hsa-miR-3651 hsa-let-7a-2* hsa-miR-30d hsa-miR-342-3p hsa-miR-570 hsa-miR-30a

		SwitchGear 3'UTR luciferase reporter plasmid: FBXO34 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FBXO34 (see all 7) OriGene shRNA RFP: FBXO34 OriGene siRNA: FBXO34
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FBXO34

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FBXO34 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FBXO34 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): FBXO34 (NM_152231)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for FBXO34
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FBXO34

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FBXO34 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat FBXO34
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FBXO34
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FBXO34

Additional cDNA sequence:

AK000732.1 AK092873.1 AK092879.1 AK225367.1 BC063526.1 BC095482.1 BC109120.1 BC109121.1

BX248268.1 CR457249.1

8 DOTS entries:

DT.215414 DT.100842638 DT.97786119 DT.100691005 DT.120786678 DT.97855373 DT.100708683 DT.100816666

8 AceView cDNA sequences:

AF531436 CN479244 AL834124 AI653349 AI653064 AI653082 AI672080 BF898625

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for FBXO34 About this scheme

ExUns:	1a	·	1b	^	2a	·	2b	·	2c	^	3	^	4a	·	4b	·	4c	·	4d	·	4e	·	4f	^	5
SP1:									-								-		-		-		-
SP2:					-		-		-		-
SP3:					-		-		-		-		-
SP4:											-
SP5:									-		-

ECgene alternative splicing isoforms for FBXO34

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

FBXO34 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CATCTTAAAT

About this image

FBXO34 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Definitive endoderm-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See FBXO34 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FBXO34

SOURCE GeneReport for Unigene cluster: Hs.525348

SABiosciences Custom PCR Arrays for FBXO34

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FBXO34 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat FBXO34
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FBXO34
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FBXO34

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FBXO34

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for FBXO34 gene from 4/10 species (see all 10) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	FBXO34¹	F-box protein 34	66.04(n) 62.88(a)		423554 NM_001031213.1 NP_001026384.1
lizard (Anolis carolinensis)	Reptilia	FBXO34⁶	--	52(a)	1 ↔ 1	GL343325.1(321913-325073)
tropical clawed frog (Xenopus tropicalis)	Amphibia	Str.14993²	Transcribed sequence with moderate similarity to protein more	74.81(n)		142010871
zebrafish (Danio rerio)	Actinopterygii	wu:fb99d03¹	wu:fb99d03	53.63(n) 47.46(a)		323474 XM_002665151.1 XP_002665197.1

ENSEMBL Gene Tree for FBXO34 (if available)
TreeFam Gene Tree for FBXO34 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for FBXO34 gene

FBXO46²

FBXO34 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 14 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs143796130^1,2	C	--	55736293(+)	`GTTTG-/TTTTTT`	1	--	us2k¹		0	--	--	--	--
rs188524047^1,2		--	55736296(+)	`TGTTTG/TTTTTT`	1	--	us2k¹		0	--	--	--	--
rs116543643^1,2	F,	--	55736356(+)	`TGTGGT/GCTCAG`	1	--	us2k¹		1		WA	118
rs75141260^1,2	C,	--	55736417(+)	`TCCCAG/AGTTGC`	1	--	us2k¹		2		WA CSA	3
rs142200847^1,2		--	55736450(+)	`CACACC/TGGGCT`	1	--	us2k¹		0	--	--	--	--
rs112280038^1,2		--	55736521(+)	`CCTGAC/TCTCAA`	1	--	us2k¹		1		CSA	2
rs148125573^1,2		--	55736579(+)	`AGCCAC/TCATGC`	1	--	us2k¹		0	--	--	--	--
rs140992662^1,2		--	55736597(+)	`GAATCA/CAGAGG`	1	--	us2k¹		0	--	--	--	--
rs10149926^1,2	C,	--	55736767(+)	`CCATAT/CAACAC`	1	--	us2k¹		4		WA CSA EA	242
rs202245973^1,2		--	55736782(+)	`CTTAA-/TTTTTT`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for FBXO34 (55738021 - 55828636 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for FBXO34
1 CNV: 5747

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FBXO34

DNA2.0 Custom Variant and Variant Library Synthesis for FBXO34

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

FBXO34 for disorders About MalaCards

FBXO34 for disorders About GeneDecksing

OMIM gene information: 609104 OMIM disorders: --

Export disorders for FBXO34 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for FBXO34 gene integrated from 9 sources:
(articles sorted by number of sources associating them with FBXO34)

Utopia: connect your pdf to the dynamic
world of online information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)¹ Lin Y.Y....Boeke J.D. (2012)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)
A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)¹ Stelzl U.... Wanker E.E. (2005)
High-throughput mapping of a dynamic signaling network in mammalian cells. (PubMed id 15761153)¹ Barrios-Rodiles M....Wrana J.L. (2005)
Systematic analysis and nomenclature of mammalian F-box proteins. (PubMed id 15520277)¹ Jin J....Harper J.W. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )² Aoki H.... Hino O. (2000)
Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)¹ Maruyama K. and Sugano S. (1994)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 55030	HGNC: 20201	AceView: FBXO34.2	Ensembl:ENSG00000178974	euGenes: HUgn55030
ECgene: FBXO34	H-InvDB: FBXO34

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for FBXO34	Pharmacogenomics, SNPs, Pathways

Intellectual Property for FBXO34 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for FBXO34 gene:
Search GeneIP for patents involving FBXO34

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for FBXO34
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FBXO34		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FBXO34
	Browse OriGene Protein Over-expression Lysates		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for FBXO34		OriGene 3'-UTR Clone for FBXO34
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FBXO34		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FBXO34
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for FBXO34		OriGene Custom Protein Services for FBXO34
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FBXO34
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FBXO34
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FBXO34
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FBXO34
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FBXO34
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FBXO34

	GenScript Custom Purified and Recombinant Proteins Services for FBXO34		GenScript cDNA clones with any tag delivered in your preferred vector for FBXO34
	GenScript Custom Assay Services for FBXO34		GenScript Custom Superior Antibodies Services for FBXO34
	GenScript Custom overexpressing Cell Line Services for FBXO34		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in FBXO34 promoter
	Search Chromatin IP Primers for FBXO34
	RT² qPCR Primer Assay in human, mouse, rat FBXO34
	Search GNC Networks for FBXO34
	SABiosciences Custom PCR Arrays for FBXO34

Search Tocris compounds for FBXO34

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	FBXO34 antibodies
	FBXO34 proteins
	FBXO34 lysates

	Search for Antibodies for FBXO34 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for FBXO34
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

FBXO34 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for FBXO34

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FBXO34

	SwitchGear 3'UTR luciferase reporter plasmids for FBXO34
	SwitchGear Promoter luciferase reporter plasmids for FBXO34

ThermoFisher Antibody for FBXO34

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FBXO34

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes FBXO34 gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4

Advanced Search

Export list of displayed genes

FBXO34 Gene

F-box protein 34

Aliases
for FBXO34 gene

Summaries
for FBXO34 gene

Genomic Views
for FBXO34 gene

Proteins
for FBXO34 gene

Protein Domains /
Families
for FBXO34 gene

Function
for FBXO34 gene

Pathways & Interactions
for FBXO34 gene

Drugs & Compounds
for FBXO34 gene

Transcripts
for FBXO34 gene

Expression
for FBXO34 gene

Orthologs
for FBXO34 gene

Paralogs
for FBXO34 gene

Genomic Variants
for FBXO34 gene

Disorders / Diseases
for FBXO34 gene

Publications
for FBXO34 gene

External Searches for FBXO34 gene

Genome Databases showing FBXO34 gene

Other Databases showing FBXO34 gene

Specialized Databases showing FBXO34 gene

Intellectual Property
for FBXO34 gene

Products
for FBXO34 gene

View Random Gene

Advanced Search

Export list of displayed genes

FBXO34 Gene

F-box protein 34

Aliasesfor FBXO34 gene

Summariesfor FBXO34 gene

Genomic Viewsfor FBXO34 gene

Proteinsfor FBXO34 gene

Protein Domains /Familiesfor FBXO34 gene

Functionfor FBXO34 gene

Pathways & Interactionsfor FBXO34 gene

Drugs & Compoundsfor FBXO34 gene

Transcriptsfor FBXO34 gene

Expression for FBXO34 gene

Orthologsfor FBXO34 gene

Paralogsfor FBXO34 gene

Genomic Variantsfor FBXO34 gene

Disorders / Diseasesfor FBXO34 gene

Publicationsfor FBXO34 gene

External Searches for FBXO34 gene

Genome Databases showing FBXO34 gene

Other Databases showing FBXO34 gene

Specialized Databases showing FBXO34 gene

Intellectual Propertyfor FBXO34 gene

Productsfor FBXO34 gene

View Random Gene

Aliases
for FBXO34 gene

Summaries
for FBXO34 gene

Genomic Views
for FBXO34 gene

Proteins
for FBXO34 gene

Protein Domains /
Families
for FBXO34 gene

Function
for FBXO34 gene

Pathways & Interactions
for FBXO34 gene

Drugs & Compounds
for FBXO34 gene

Transcripts
for FBXO34 gene

Expression
for FBXO34 gene

Orthologs
for FBXO34 gene

Paralogs
for FBXO34 gene

Genomic Variants
for FBXO34 gene

Disorders / Diseases
for FBXO34 gene

Publications
for FBXO34 gene

Intellectual Property
for FBXO34 gene

Products
for FBXO34 gene