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FBXO33 Gene

protein-coding   GIFtS: 49
GCID: GC14M039866

F-Box Protein 33

(Previous name: F-box only protein 33)
  See FBXO33-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
F-Box Protein 331 2
F-Box Only Protein 331 2
BMND122 5
FBX333 5
Fbx332
c14_52472

External Ids:    HGNC: 198331   Entrez Gene: 2541702   Ensembl: ENSG000001653557   OMIM: 6091035   UniProtKB: Q7Z6M23   

Export aliases for FBXO33 gene to outside databases

Previous GC identifers: GC14M033724 GC14M037856 GC14M038936 GC14M019981


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for FBXO33 Gene:
This locus represents an member of the F-box gene family. The encoded protein contains an F-box motif and a domain
that might form a structure similar to a leucine-rich repeat found in placental RNAse inhibitor. This locus may
be associated with copy number variation of UGT2B17 (GeneID 7367), which has been associated with susceptibility
to osteoporosis.(provided by RefSeq, Sep 2010)

GeneCards Summary for FBXO33 Gene:
FBXO33 (F-box protein 33) is a protein-coding gene. Diseases associated with FBXO33 include osteoporosis.

UniProtKB/Swiss-Prot: FBX33_HUMAN, Q7Z6M2
Function: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex
which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes
and binds to phosphorylated target proteins. Recognizes YBX1 (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000014.8  NC_018925.2  NT_026437.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the FBXO33 gene promoter:
         Pax-5   ATF-2   XBP-1   Nkx2-5   C/EBPalpha   HOXA5   HSF2   c-Myb   Cart-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFBXO33 promoter sequence
   Search Chromatin IP Primers for FBXO33

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FBXO33


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q21.1   Ensembl cytogenetic band:  14q21.1   HGNC cytogenetic band: 14q13.3

FBXO33 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FBXO33 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M039866:  view genomic region     (about GC identifiers)

Start:
39,865,577 bp from pter      End:
39,901,704 bp from pter
Size:
36,128 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: FBX33_HUMAN, Q7Z6M2 (See protein sequence)
Recommended Name: F-box only protein 33  
Size: 555 amino acids; 62630 Da
Subunit: Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXO33) formed of CUL1, SKP1,
RBX1 and FBXO33. Interacts via its N-terminus with YBX1 CSD domain. Directly interacts with SKP1 and CUL1 (By
similarity)
Secondary accessions: Q6PIR2 Q86TR2 Q86YE0

Explore the universe of human proteins at neXtProt for FBXO33: NX_Q7Z6M2

Explore proteomics data for FBXO33 at MOPED


See FBXO33 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_976046.1  
ENSEMBL proteins: 
 ENSP00000298097   ENSP00000451277   ENSP00000450974  

FBXO33 Human Recombinant Protein Products:

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Cloud-Clone Corp. Proteins for FBXO33

 
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antibodies-online proteins for FBXO33 (5 products) 

 
antibodies-online peptides for FBXO33

FBXO33 Antibody Products:

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antibodies-online antibodies for FBXO33 (18 products) 

FBXO33 Assay Products:

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Cloud-Clone Corp. CLIAs for FBXO33
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antibodies-online kits for FBXO33 (16 products) 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
FBXO: F-boxes / "other"

1 InterPro protein domain:
 IPR001810 F-box_dom

Graphical View of Domain Structure for InterPro Entry Q7Z6M2

ProtoNet protein and cluster: Q7Z6M2

UniProtKB/Swiss-Prot: FBX33_HUMAN, Q7Z6M2
Similarity: Contains 1 F-box domain


Find genes that share domains with FBXO33           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: FBX33_HUMAN, Q7Z6M2
Function: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex
which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes
and binds to phosphorylated target proteins. Recognizes YBX1 (By similarity)

     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005515protein binding IPI16797541
     
Find genes that share ontologies with FBXO33           About GenesLikeMe


Phenotypes:
     1 GenomeRNAi human phenotype for FBXO33:
 Decreased nuclei size in G2M 

     1 MGI phenotypic allele for Fbxo33 (no phenotypes)

Find genes that share phenotypes with FBXO33           About GenesLikeMe

Animal Models:
   genOway: Develop your customized and physiologically relevant rodent model for FBXO33

miRNA
Products:
    
miRTarBase miRNAs that target FBXO33:
hsa-mir-1 (MIRT023545), hsa-mir-505-3p (MIRT041067), hsa-mir-181a-5p (MIRT025123)

Block miRNA regulation of human, mouse, rat FBXO33 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate FBXO33 (see all 132):
hsa-miR-411* hsa-miR-26a-2* hsa-miR-128 hsa-miR-342-3p hsa-miR-200b hsa-miR-92b hsa-miR-490-5p hsa-miR-455-5p
SwitchGear 3'UTR luciferase reporter plasmidFBXO33 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for FBXO33
Predesigned siRNA for gene silencing in human, mouse, rat FBXO33

Gene Editing
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DNA2.0 Custom Protein Engineering Service for FBXO33

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OriGene clones in human, mouse for FBXO33 (see all 7)
OriGene ORF clones in mouse, rat for FBXO33
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GenScript: all cDNA clones in your preferred vector: FBXO33 (NM_203301)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for FBXO33
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FBXO33

Cell Line
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GenScript Custom overexpressing Cell Line Services for FBXO33
Browse ESI BIO Cell Lines and PureStem Progenitors for FBXO33 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FBXO33


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
mitochondrion2
nucleus1

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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UniProtKB/Swiss-Prot: FBX33_HUMAN, Q7Z6M2
Pathway: Protein modification; protein ubiquitination

    Pathway & Disease-focused RT2 Profiler PCR Array including FBXO33: 

          Ubiquitin Ligases in human mouse rat

Interactions:

    Search GeneGlobe Interaction Network for FBXO33

STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

Selected Interacting proteins for FBXO33 (Q7Z6M21, 2, 3 ENSP000002980974) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
InteractantInteraction Details
GeneCardExternal ID(s)
C1QBPQ070212, 3, ENSP000002256984MINT-2831634 I2D: score=1 STRING: ENSP00000225698
CUL1Q136162, 3, ENSP000003268044MINT-2831398 I2D: score=1 STRING: ENSP00000326804
HSPA9P386462, 3, ENSP000002971854MINT-2831598 I2D: score=1 STRING: ENSP00000297185
IPO5O004102, 3, ENSP000002615744MINT-2831534 I2D: score=1 STRING: ENSP00000261574
RBX1P628772, 3, ENSP000002162254MINT-2831467 I2D: score=1 STRING: ENSP00000216225
About this table

Gene Ontology (GO): 1 biological process term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0016567protein ubiquitination IEA--

Find genes that share ontologies with FBXO33           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for FBXO33 (FBX33)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for FBXO33 gene: 
NM_203301.3  

Unigene Cluster for FBXO33:

F-box protein 33
Hs.146632  [show with all ESTs]
Unigene Representative Sequence: NM_203301
3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000298097(uc001wvk.3) ENST00000554190 ENST00000554932
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat FBXO33 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate FBXO33 (see all 132):
hsa-miR-411* hsa-miR-26a-2* hsa-miR-128 hsa-miR-342-3p hsa-miR-200b hsa-miR-92b hsa-miR-490-5p hsa-miR-455-5p
SwitchGear 3'UTR luciferase reporter plasmidFBXO33 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for FBXO33
Predesigned siRNA for gene silencing in human, mouse, rat FBXO33
Clone
Products:
     
OriGene clones in human, mouse for FBXO33 (see all 7)
OriGene ORF clones in mouse, rat for FBXO33
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: FBXO33 (NM_203301)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for FBXO33
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FBXO33
Primer
Products:
    
OriGene qPCR primer pairs and template standards for FBXO33
OriGene qSTAR qPCR primer pairs in human, mouse for FBXO33
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FBXO33
  QuantiTect SYBR Green Assays in human, mouse, rat FBXO33
  QuantiFast Probe-based Assays in human, mouse, rat FBXO33

Additional mRNA sequence: 

AK294140.1 BC030611.1 BC042535.1 BC053537.1 BC068566.1 BX248772.1 

5 DOTS entries:

DT.211025  DT.312076  DT.65287402  DT.120766501  DT.92418848 

Selected AceView cDNA sequences (see all 110):

BQ286342 AI656037 BC068566 AI693807 AW772348 AI207351 BX093575 NM_203301 
AL040793 BM979476 BM565461 BM991451 BX346963 BM988543 BQ775793 BC053537 
CA390622 AI989795 BQ185585 AI219242 BC042535 AI561122 AI695035 AI095389 

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for FBXO33    About this scheme

ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5a · 5b
SP1:                                                
SP2:                                                
SP3:                                                
SP4:                          -     -               


ECgene alternative splicing isoforms for FBXO33

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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FBXO33 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: ACTACTTTTA
FBXO33 Expression
About this image

FBXO33 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

FBXO33 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.146632
    Pathway & Disease-focused RT2 Profiler PCR Array including FBXO33: 
          Ubiquitin Ligases in human mouse rat

Primer
Products:
OriGene qPCR primer pairs and template standards for FBXO33
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QuantiFast Probe-based Assays in human, mouse, rat FBXO33
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FBXO33

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for FBXO33 gene from Selected species (see all 14)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Fbxo331 , 5 F-box protein 331, 5 90.33(n)1
92.79(a)1
  12 (26.03 cM)5
706111  NM_001033156.41  NP_001028328.21 
 592006555 
chicken
(Gallus gallus)
Aves FBXO331 F-box protein 33 84.2(n)
89.38(a)
  428887  XM_426443.4  XP_426443.3 
lizard
(Anolis carolinensis)
Reptilia FBXO336
F-box protein 33
79(a)
1 ↔ 1
1(23855650-23877893)
African clawed frog
(Xenopus laevis)
Amphibia Xl.69802 Xenopus laevis transcribed sequences 89.95(n)    AW640340.1 
zebrafish
(Danio rerio)
Actinopterygii wufb78e032 Transcribed sequences 82.38(n)    57043160 
fruit fly
(Drosophila melanogaster)
Insecta CG49116
--
24(a)
1 ↔ 1
3L(9062749-9065831)


ENSEMBL Gene Tree for FBXO33 (if available)
TreeFam Gene Tree for FBXO33 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for FBXO33 (see all 786)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 14 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1503479501,2
C--19995903(+) GACTT-/CCCCCC 1 -- int10--------
rs1404221401,2
--20006108(+) CACAC-/ACAC  
  ACACAA
ACACA
1 -- int10--------
rs2005571641,2
C--20006117(+) TGTGTA/C/G/
        
TGTGT
1 -- int10--------
rs2011104941,2
C--20862238(+) AAGGGG/TGGGGG 1 -- ds50010--------
rs124330451,2
C,H--20862241(+) GGTGGC/GGGGGG 1 -- ds50011Minor allele frequency- G:0.00WA 2
rs2009854071,2
C--20862252(+) GGGGGC/GGGGGG 1 -- ds50010--------
rs1896529681,2
--20862258(+) GGGGGC/GGCGTC 1 -- ds50010--------
rs620007201,2
C--20862265(+) CGTCTA/CCAAAG 1 -- ds50014Minor allele frequency- C:0.09NA WA EA 360
rs3737004881,2
C--20862394(+) CCTGCA/GCCTCT 1 -- ds50010--------
rs171091701,2
C,F,H--20862430(+) TTGGTG/AGCTGT 1 -- ds50018Minor allele frequency- A:0.04NA NS EA WA 678

HapMap Linkage Disequilibrium report for FBXO33 (39865577 - 39901704 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for FBXO33:    About this table    
Variant IDTypeSubtypePubMed ID
esv2748623CNV Deletion23290073
nsv832774CNV Loss17160897

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing FBXO33
DNA2.0 Custom Variant and Variant Library Synthesis for FBXO33

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 609103    OMIM disorders: --

1 disease for FBXO33:    
About MalaCards
osteoporosis


Find genes that share disorders with FBXO33           About GenesLikeMe

Genetic Association Database (GAD): FBXO33
Human Genome Epidemiology (HuGE) Navigator: FBXO33 (1 document)

Export disorders for FBXO33 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for FBXO33 gene, integrated from 10 sources (see all 17):
(articles sorted by number of sources associating them with FBXO33)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  3. Proteasomal degradation of the multifunctional regulator YB-1 is mediated by an F-Box protein induced during programmed cell death. (PubMed id 16797541)1, 9 Lutz M.... von Melchner H. (FEBS Lett. 2006)
  4. Genome wide association study for plasma levels of natural anticoagulant inhibitors and protein C anticoagulant pathway: the MARTHA project. (PubMed id 22443383)4 Oudot-Mellakh T....Morange P.E. (Br. J. Haematol. 2012)
  5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
  6. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
  7. Genome-wide association study of electrocardiographic and heart rate variability traits: the Framingham Heart Study. (PubMed id 17903306)4 Newton-Cheh C....Larson M.G. (BMC Med. Genet. 2007)
  8. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (BMC Med. Genet. 2007)
  9. Genome-wide association with diabetes-related traits in the Framingham Heart Study. (PubMed id 17903298)4 Meigs J.B....Dupuis J. (BMC Med. Genet. 2007)
  10. Genome-wide association with select biomarker traits in the Framingham Heart Study. (PubMed id 17903293)4 Benjamin E.J....Vasan R.S. (BMC Med. Genet. 2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 254170 HGNC: 19833 AceView: FBXO33 Ensembl:ENSG00000165355 euGenes: HUgn254170
ECgene: FBXO33 H-InvDB: FBXO33

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for FBXO33 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for FBXO33 gene:
Search GeneIP for patents involving FBXO33

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from genOway)
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