Aliases for FBXO28 Gene
External Ids for FBXO28 Gene
Previous GeneCards Identifiers for FBXO28 Gene
Members of the F-box protein family, such as FBXO28, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
GeneCards Summary for FBXO28 Gene
UniProtKB/Swiss-Prot for FBXO28 Gene
Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.