FBXL3 Gene
protein-coding GIFtS: 54
GCID: GC13M077566
|
|
F-box and leucine-rich repeat protein 3(Previous name: F-box and leucine-rich repeat protein 3A ) (Previous symbol: FBXL3A)
| |
Aliases for FBXL3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| F-Box And Leucine-Rich Repeat Protein 31 2 | | FBL31 2 5 | | FBL3A1 2 3 5 | | F-Box/LRR-Repeat Protein 3A2 3 | | FBXL3A1 2 3 5 | | F-Box Protein Fbl3a2 | | F-Box And Leucine-Rich Repeat Protein 3A1 2 3 | | F-Box/LRR-Repeat Protein 32 |
Export aliases for FBXL3 gene to outside databasesPrevious GC identifers: GC13M076477 GC13M058277 |
Summaries for FBXL3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for FBXL3: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif,the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs(SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either differentprotein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fblsclass and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus.(provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: FBXL3_HUMAN, Q9UKT7Function: Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complexinvolved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequentdegradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteinsand promotes their ubiquitination and degradation Gene Wiki entry for FBXL3
|
Genomic Views for FBXL3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000013.10 NC_018924.1 NT_024524.14
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the FBXL3 gene promoter: Nkx3-1 Nkx3-1 v4 GCNF POU3F2 (N-Oct-5b) POU3F2 (N-Oct-5a) POU3F2 Nkx3-1 v2 GCNF-1 Nkx3-1 v3 GCNF-2 Other transcription factors
Search SABiosciences Chromatin IP Primers for FBXL3
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FBXL3 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 13q22 Ensembl cytogenetic band: 13q22.3 HGNC cytogenetic band: 13q22FBXL3 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 13 GeneLoc Exon Structure GeneLoc location for GC13M077566: view genomic region
(about GC identifiers)
Start:
|
77,566,740 bp from pter |
End:
|
77,601,331 bp from pter |
Size:
|
34,592 bases |
Orientation:
|
minus strand |
|
Proteins for FBXL3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: FBXL3_HUMAN, Q9UKT7 (See
protein sequence)Recommended Name: F-box/LRR-repeat protein 3 Size: 428 amino acids; 48707 Da
Subunit: Part of a SCF (SKP1-cullin-F-box) protein ligase complex. Interacts with CRY1 and CRY2
Subcellular location: Nucleus. Cytoplasm. Note=Predominantly nuclear
Secondary accessions: B2RB04 Q9P122Explore the universe of human proteins at neXtProt for FBXL3: NX_Q9UKT7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UKT7 FBXL3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_036290.1 ENSEMBL proteins: ENSP00000347834 ENSP00000412183 Reactome Protein details: Q9UKT7 Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
FBXL3 for ontologies About GeneDecksing
FBXL3 Antibody Products: Assay Products for FBXL3: |
Protein
Domains / Families for FBXL3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FBXL3 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9UKT7ProtoNet protein and cluster: Q9UKT7 UniProtKB/Swiss-Prot: FBXL3_HUMAN, Q9UKT7Similarity: Contains 1 F-box domainSimilarity: Contains 7 LRR (leucine-rich) repeats |
Function for FBXL3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: FBXL3_HUMAN, Q9UKT7Function: Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complexinvolved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequentdegradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteinsand promotes their ubiquitination and degradation
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FBXL3 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FBXL3 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FBXL3 (NM_012158) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FBXL3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FBXL3  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FBXL3 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
FBXL3 for ontologies About GeneDecksing
4 GenomeRNAi human phenotypes for FBXL3: Animal Models: 5 MGI mutant phenotypes (inferred from 5 alleles ) (MGI details for Fbxl3):
FBXL3 for phenotypes About GeneDecksing
|
Pathways & Interactions for FBXL3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Chaperonin-mediated protein folding | | | 2 | Circadian rhythm - mammal | | | 3 | Signal Transduction | | | 4 | Asparagine N-linked glycosylation | |
Pathway sources See GeneCards unified pathways Show all pathways
5/6
Reactome Pathways for FBXL3 (see all 6)
1
Kegg Pathway (Kegg details for FBXL3):
FBXL3 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FBXL3
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/36 Interacting proteins for FBXL3 (Q9UKT72, 3 ENSP000003478344) via UniProtKB, MINT, STRING, and/or I2D (see all 36)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
FBXL3 for ontologies About GeneDecksing
|
Drugs & Compounds for FBXL3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for FBXL3 Search CenterWatch for drugs/clinical trials and news about FBXL3 
|
Transcripts for FBXL3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for FBXL3 gene: NM_012158.2 Unigene Cluster for FBXL3: F-box and leucine-rich repeat protein 3 Hs.508284 [show with all ESTs]Unigene Representative Sequence: NM_0121586 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000485797 ENST00000477982 ENST00000355619(uc001vkd.3) ENST00000417323 ENST00000470210 ENST00000472949
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FBXL3 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FBXL3 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FBXL3 (NM_012158) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FBXL3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FBXL3  |
Additional cDNA sequence: AF126028.1 AF129532.1 AK025484.1 AK314442.1 AL833187.1 BC063796.1 BC072448.1 15 DOTS entries: DT.447214 DT.75169715 DT.120781368 DT.75180488 DT.120781353 DT.120781356 DT.120781363 DT.120781399 DT.120781401 DT.70103308 DT.75150425 DT.95146296 DT.99992278 DT.95241428 DT.95264712 24/202 AceView cDNA sequences (see all 202): AA488914 CD677408 N50224 BQ424398 AI474918 AA805942 BM478132 AW511185 AF129532 CB216156 AI866697 BF574334 CA388641 AI133484 Z43904 Z39951 T25856 BU754202 BM696524 AA287383 AA864593 BU190174 BQ050755 AA648533 GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for FBXL3 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | ^ | 7a | · | 7b | |
| SP1: | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for FBXL3
|
Expression for FBXL3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FBXL3 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CATTGTAGAG
About this image See FBXL3 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for FBXL3
SOURCE GeneReport for Unigene cluster: Hs.508284 UniProtKB/Swiss-Prot: FBXL3_HUMAN, Q9UKT7Tissue specificity: Widely expressed SABiosciences Expression via Pathway-Focused PCR Arrays including FBXL3:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FBXL3 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FBXL3 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FBXL3 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FBXL3 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FBXL3 |
Orthologs for FBXL3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for FBXL3 gene from 6/14 species (see all 14) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Fbxl31 , 5 |
F-box and leucine-rich repeat protein 31, 5 |
89.25(n)1 97.2(a)1 |
  |
14 (51.73 cM)5 507891 NM_015822.21 NP_056637.11 1030802395 |
chicken (Gallus gallus) |
Aves |
FBXL31 |
F-box and leucine-rich repeat protein 3 |
81.93(n) 93.69(a) |
  |
428048 XM_425611.3 XP_425611.2 |
lizard (Anolis carolinensis) |
Reptilia |
FBXL36 |
-- |
89(a) |
1 ↔ 1 |
3(86642480-86647794) |
African clawed frog (Xenopus laevis) |
Amphibia |
Xl.102012 |
Xenopus laevis transcribed sequence with strong similarity more |
81.52(n) |
  |
48057668 |
zebrafish (Danio rerio) |
Actinopterygii |
570584702 |
-- |
70.85(n) |
  |
57058470 |
honey bee (Apis mellifera) |
Insecta |
-- |
-- |
37(a) |
1 ↔ 1 |
GroupUn.12(25377-29254) |
ENSEMBL Gene Tree for FBXL3 (if available) TreeFam Gene Tree for FBXL3 (if available)  |
Paralogs for FBXL3 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for FBXL3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 13 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for FBXL3 (77566740 - 77601331 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for FBXL3: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FBXL3 |
|
Disorders
/ Diseases for FBXL3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
FBXL3 for disorders About GeneDecksing
OMIM gene information: 605653
OMIM disorders: --
2 diseases for FBXL3: About MalaCardsestrogen-receptor positive breast cancer breast cancer 1 disease from the University of Copenhagen DISEASES database for FBXL3:estrogen-receptor positive breast cancer Export disorders for FBXL3 gene to outside databases
|
Publications for FBXL3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FBXL3 gene, integrated from 9 sources (see all 16): (articles sorted by number of sources associating them with FBXL3) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Identification of a family of human F-box proteins. (PubMed id 10531035)1, 2, 3 Cenciarelli C....Pagano M. (1999)
- Five human genes encoding F-box proteins: chromosome mapping and analysis in human tumors. (PubMed id 10828603)1, 3, 9 Chiaur D.S....Pagano M. (2000)
- SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins. (PubMed id 17463251)1, 2 Busino L....Pagano M. (2007)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Polyubiquitination of the B-cell translocation gene 1 and 2 proteins is promoted by the SCF ubiquitin ligase complex containing bTrCP. (PubMed id 22975506)1 Sasajima H....Yokosawa H. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)
- Systematic analysis of human protein complexes identi fies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R....Peters J.M. (2010)
|
External Searches for FBXL3 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing FBXL3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FBXL3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FBXL3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for FBXL3 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FBXL3 gene: Search GeneIP for patents involving FBXL3
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for FBXL3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | OriGene Antibodies for FBXL3 | | OriGene shRNA RFP for FBXL3 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FBXL3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FBXL3 | | OriGene Protein Over-expression Lysate for FBXL3 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for FBXL3 | | OriGene 3'-UTR Clone for FBXL3 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FBXL3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FBXL3 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for FBXL3 | | OriGene Custom Protein Services for FBXL3 | | OriGene Custom Immunoassay Development | | |
| |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FBXL3 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FBXL3 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FBXL3 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FBXL3 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FBXL3 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FBXL3 |
| |
 |  |  |  | |
| | | Search Tocris compounds for FBXL3 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | FBXL3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FBXL3 |
|  |  |  | | | ThermoFisher Antibodies for FBXL3 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FBXL3 |
|
|
|
|