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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FBXL3 Gene

protein-coding   GIFtS: 54
GCID: GC13M077566

F-box and leucine-rich repeat protein 3

(Previous name: F-box and leucine-rich repeat protein 3A )
(Previous symbol: FBXL3A)
 Explore 2 diseases affiliated with
FBXL3 via our new
 Human Malady Compendium 
Biological research products
for FBXL3
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
F-Box And Leucine-Rich Repeat Protein 31 2     FBL31 2 5
FBL3A1 2 3 5     F-Box/LRR-Repeat Protein 3A2 3
FBXL3A1 2 3 5     F-Box Protein Fbl3a2
F-Box And Leucine-Rich Repeat Protein 3A1 2 3     F-Box/LRR-Repeat Protein 32

External Ids:    HGNC: 135991   Entrez Gene: 262242   Ensembl: ENSG000000058127   OMIM: 6056535   UniProtKB: Q9UKT73   

Export aliases for FBXL3 gene to outside databases

Previous GC identifers: GC13M076477 GC13M058277


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FBXL3:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif,
the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs
(SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3
classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different
protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls
class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus.
(provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: FBXL3_HUMAN, Q9UKT7
Function: Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex
involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent
degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins
and promotes their ubiquitination and degradation

Gene Wiki entry for FBXL3


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000013.10  NC_018924.1  NT_024524.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FBXL3 gene promoter:
         Nkx3-1   Nkx3-1 v4   GCNF   POU3F2 (N-Oct-5b)   POU3F2 (N-Oct-5a)   POU3F2   Nkx3-1 v2   GCNF-1   Nkx3-1 v3   GCNF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFBXL3 promoter sequence
   Search SABiosciences Chromatin IP Primers for FBXL3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FBXL3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q22   Ensembl cytogenetic band:  13q22.3   HGNC cytogenetic band: 13q22

FBXL3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FBXL3 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13M077566:  view genomic region     (about GC identifiers)

Start:
77,566,740 bp from pter      End:
77,601,331 bp from pter
Size:
34,592 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: FBXL3_HUMAN, Q9UKT7 (See protein sequence)
Recommended Name: F-box/LRR-repeat protein 3  
Size: 428 amino acids; 48707 Da
Subunit: Part of a SCF (SKP1-cullin-F-box) protein ligase complex. Interacts with CRY1 and CRY2
Subcellular location: Nucleus. Cytoplasm. Note=Predominantly nuclear
Secondary accessions: B2RB04 Q9P122

Explore the universe of human proteins at neXtProt for FBXL3: NX_Q9UKT7

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UKT7

  • FBXL3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_036290.1  
    ENSEMBL proteins: 
     ENSP00000347834   ENSP00000412183  
    Reactome Protein details: Q9UKT7
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    Uscn Proteins for FBXL3

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000151ubiquitin ligase complex NAS10531035
    GO:0005634nucleus ISS--
    GO:0005737cytoplasm IEA--
    GO:0019005SCF ubiquitin ligase complex IDA17463251


    FBXL3 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    FBXL3 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR001810 F-box_dom_cyclin-like

    Graphical View of Domain Structure for InterPro Entry Q9UKT7

    ProtoNet protein and cluster: Q9UKT7

    UniProtKB/Swiss-Prot: FBXL3_HUMAN, Q9UKT7
    Similarity: Contains 1 F-box domain
    Similarity: Contains 7 LRR (leucine-rich) repeats


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: FBXL3_HUMAN, Q9UKT7
    Function: Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex
    involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent
    degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins
    and promotes their ubiquitination and degradation

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    hsa-miR-142-5p hsa-miR-106a hsa-let-7a-2* hsa-miR-374a hsa-miR-3667-5p hsa-miR-9 hsa-miR-93 hsa-miR-526b*
    SwitchGear 3'UTR luciferase reporter plasmidFBXL3 3' UTR sequence
    Inhib. RNA
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004842ubiquitin-protein ligase activity NAS10531035
    GO:0005515protein binding IPI17463251


    FBXL3 for ontologies           About GeneDecksing


    4 GenomeRNAi human phenotypes for FBXL3:
     Decreased BPV1 E2 protein expr  Increased HPV18 LCR reporter a  Increased cell death HMECs cel  Increased circadian period len 

    Animal Models:
         5 MGI mutant phenotypes (inferred from 5 alleles(MGI details for Fbxl3):
     behavior/neurological  hematopoietic system  homeostasis/metabolism  integument  no phenotypic analysis 

    FBXL3 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Chaperonin-mediated protein folding
    Chaperonin-mediated protein folding1.00
    Association of TriC/CCT with target proteins during biosynthesis0.60
    Protein folding0.91
    2Circadian rhythm - mammal
    Circadian rhythm - mammal1.00
    Circadian Clock0.41
    3Signal Transduction
    Ubiquitination of CRY Proteins0.57
    4Asparagine N-linked glycosylation
    Metabolism of proteins0.15

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/6        Reactome Pathways for FBXL3 (see all 6)
        Association of TriC/CCT with target proteins during biosynthesis
    Chaperonin-mediated protein folding
    Circadian Clock
    Metabolism of proteins
    Protein folding


    1         Kegg Pathway  (Kegg details for FBXL3):
        Circadian rhythm - mammal


    FBXL3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FBXL3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/36 Interacting proteins for FBXL3 (Q9UKT72, 3 ENSP000003478344) via UniProtKB, MINT, STRING, and/or I2D (see all 36)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SKP1P632083, ENSP000002314874I2D: score=3 STRING: ENSP00000231487
    CRY1Q165263, ENSP000000085274I2D: score=1 STRING: ENSP00000008527
    CRY2Q49AN03, ENSP000004067514I2D: score=1 STRING: ENSP00000406751
    CUL1Q136163, ENSP000003268044I2D: score=1 STRING: ENSP00000326804
    UBE2D2P628373, ENSP000003817174I2D: score=1 STRING: ENSP00000381717
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016567protein ubiquitination NAS10531035
    GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IDA17463251
    GO:0042752regulation of circadian rhythm IMP17463251
    GO:0043161proteasomal ubiquitin-dependent protein catabolic process ----
    GO:0048511rhythmic process IEA--


    FBXL3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for FBXL3
    Search CenterWatch for drugs/clinical trials and news about FBXL3 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    About This Section

    REFSEQ mRNAs for FBXL3 gene: 
    NM_012158.2  

    Unigene Cluster for FBXL3:

    F-box and leucine-rich repeat protein 3
    Hs.508284  [show with all ESTs]
    Unigene Representative Sequence: NM_012158
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000485797 ENST00000477982 ENST00000355619(uc001vkd.3) ENST00000417323
    ENST00000470210 ENST00000472949

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    hsa-miR-142-5p hsa-miR-106a hsa-let-7a-2* hsa-miR-374a hsa-miR-3667-5p hsa-miR-9 hsa-miR-93 hsa-miR-526b*
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    Inhib. RNA
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    Additional cDNA sequence: 

    AF126028.1 AF129532.1 AK025484.1 AK314442.1 AL833187.1 BC063796.1 BC072448.1 

    15 DOTS entries:

    DT.447214  DT.75169715  DT.120781368  DT.75180488  DT.120781353  DT.120781356  DT.120781363  DT.120781399 
    DT.120781401  DT.70103308  DT.75150425  DT.95146296  DT.99992278  DT.95241428  DT.95264712 

    24/202 AceView cDNA sequences (see all 202):

    AA488914 CD677408 N50224 BQ424398 AI474918 AA805942 BM478132 AW511185 
    AF129532 CB216156 AI866697 BF574334 CA388641 AI133484 Z43904 Z39951 
    T25856 BU754202 BM696524 AA287383 AA864593 BU190174 BQ050755 AA648533 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for FBXL3 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b
    SP1:                          -                                                               
    SP2:                          -     -     -     -                                             
    SP3:                          -                 -                                             
    SP4:              -     -     -                                                               
    SP5:                    -     -                                                               


    ECgene alternative splicing isoforms for FBXL3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FBXL3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CATTGTAGAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See FBXL3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FBXL3

    SOURCE GeneReport for Unigene cluster: Hs.508284

    UniProtKB/Swiss-Prot: FBXL3_HUMAN, Q9UKT7
    Tissue specificity: Widely expressed

        SABiosciences Expression via Pathway-Focused PCR Arrays including FBXL3: 
              Circadian Rhythms in human mouse rat
              Ubiquitin Ligases in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FBXL3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for FBXL3 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fbxl31 , 5 F-box and leucine-rich repeat protein 31, 5 89.25(n)1
    97.2(a)1
      14 (51.73 cM)5
    507891  NM_015822.21  NP_056637.11 
     1030802395 
    chicken
    (Gallus gallus)
    Aves FBXL31 F-box and leucine-rich repeat protein 3 81.93(n)
    93.69(a)
      428048  XM_425611.3  XP_425611.2 
    lizard
    (Anolis carolinensis)
    Reptilia FBXL36
    --
    89(a)
    1 ↔ 1
    3(86642480-86647794)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.102012 Xenopus laevis transcribed sequence with strong similarity more 81.52(n)    48057668 
    zebrafish
    (Danio rerio)
    Actinopterygii 570584702   -- 70.85(n)    57058470 
    honey bee
    (Apis mellifera)
    Insecta --
    --
    37(a)
    1 ↔ 1
    GroupUn.12(25377-29254)


    ENSEMBL Gene Tree for FBXL3 (if available)
    TreeFam Gene Tree for FBXL3 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    4 NCBI SNPs in FBXL3 are shown     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1829147261,2
    --77600849(+) GCCCCA/GGCCCC 1 -- int10--------
    rs106753811,2
    C,--77603116(+) AAAAC-/GTGTTTA 1 -- us2k1 tfbs30--------
    rs771072251,2
    ----58290272(+) AAAAAG/AGCTTA 1 -- int11Minor allele frequency- A:0.00NA 2
    rs1117382141,2
    ----77600872(+) CACCCC/TACCCC 1 -- int10--------

    HapMap Linkage Disequilibrium report for FBXL3 (77566740 - 77601331 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for FBXL3: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FBXL3
    DNA2.0 Custom Variant and Variant Library Synthesis for FBXL3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    FBXL3 for disorders           About GeneDecksing

    OMIM gene information: 605653    OMIM disorders: --

    2 diseases for FBXL3:    About MalaCards
    estrogen-receptor positive breast cancer    breast cancer

    1 disease from the University of Copenhagen DISEASES database for FBXL3:
    estrogen-receptor positive breast cancer

    Export disorders for FBXL3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FBXL3 gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with FBXL3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of a family of human F-box proteins. (PubMed id 10531035)1, 2, 3 Cenciarelli C....Pagano M. (1999)
    2. Five human genes encoding F-box proteins: chromosome mapping and analysis in human tumors. (PubMed id 10828603)1, 3, 9 Chiaur D.S....Pagano M. (2000)
    3. SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins. (PubMed id 17463251)1, 2 Busino L....Pagano M. (2007)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Polyubiquitination of the B-cell translocation gene 1 and 2 proteins is promoted by the SCF ubiquitin ligase complex containing bTrCP. (PubMed id 22975506)1 Sasajima H....Yokosawa H. (2012)
    6. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    7. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    8. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    9. Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)
    10. Systematic analysis of human protein complexes identi fies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R....Peters J.M. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26224 HGNC: 13599 AceView: FBXL3 Ensembl:ENSG00000005812 euGenes: HUgn26224
    ECgene: FBXL3 Kegg: 26224 H-InvDB: FBXL3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FBXL3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for FBXL3 gene:
    Search GeneIP for patents involving FBXL3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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