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FBXL19 Gene

protein-coding   GIFtS: 48
GCID: GC16P030934

F-Box And Leucine-Rich Repeat Protein 19

  See FBXL19-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
F-Box And Leucine-Rich Repeat Protein 191 2 3     Fbl192
Jumonji C Domain-Containing Histone Demethylase 1C1 2     JHDM1C2
FBL193 5     F-Box/LRR-Repeat Protein 192
CXXC112     

External Ids:    HGNC: 253001   Entrez Gene: 546202   Ensembl: ENSG000000993647   OMIM: 6090855   UniProtKB: Q6PCT23   

Export aliases for FBXL19 gene to outside databases

Previous GC identifers: GC16P030970 GC16P030841 GC16P030843 GC16P028498


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for FBXL19 Gene:
This gene encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. The encoded protein is
reported to bind to the transmembrane receptor interleukin 1 receptor-like 1 and regulate its ubiquitination and
degradation. This protein has been linked to the regulation of pulmonary inflammation and psoriasis. Alternative
splicing results in multiple transcript variants. (provided by RefSeq, Aug 2013)

GeneCards Summary for FBXL19 Gene:
FBXL19 (F-box and leucine-rich repeat protein 19) is a protein-coding gene. Diseases associated with FBXL19 include psoriasis. An important paralog of this gene is PHF2.

UniProtKB/Swiss-Prot: FXL19_HUMAN, Q6PCT2
Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex
(By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000016.9  NC_018927.2  NT_187260.1  
Regulatory elements:
   Regulatory transcription factor binding sites in the FBXL19 gene promoter:
         NF-1   AP-4   CUTL1   STAT5A   E47   CREB   deltaCREB   ARP-1   Hand1   Zic3   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for FBXL19

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FBXL19


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p11.2   Ensembl cytogenetic band:  16p11.2   HGNC cytogenetic band: 16p11.2

FBXL19 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FBXL19 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P030934:  view genomic region     (about GC identifiers)

Start:
30,934,376 bp from pter      End:
30,960,104 bp from pter
Size:
25,729 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: FXL19_HUMAN, Q6PCT2 (See protein sequence)
Recommended Name: F-box/LRR-repeat protein 19  
Size: 694 amino acids; 75707 Da
Subunit: Directly interacts with SKP1 and CUL1 (By similarity)
Caution: It is uncertain whether Met-1 or Met-21 is the initiator
Sequence caution: Sequence=AAH59173.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAC05410.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: A8MT10 Q8N789 Q9NT14
Alternative splicing: 3 isoforms:  Q6PCT2-1   Q6PCT2-2   Q6PCT2-3   

Explore the universe of human proteins at neXtProt for FBXL19: NX_Q6PCT2

Explore proteomics data for FBXL19 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See FBXL19 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001093254.2  NP_001269280.1  

    ENSEMBL proteins: 
     ENSP00000455871   ENSP00000458033   ENSP00000339712   ENSP00000455529   ENSP00000454344  
     ENSP00000397913   ENSP00000455337   ENSP00000457199   ENSP00000369666  

    FBXL19 Human Recombinant Protein Products:

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    Novus Biologicals FBXL19 Protein
    Novus Biologicals FBXL19 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for FBXL19

     
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    antibodies-online proteins for FBXL19 (3 products) 

     
    antibodies-online peptides for FBXL19

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    antibodies-online antibodies for FBXL19 (11 products) 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    FBXL: F-boxes / Leucine-rich repeats

    Selected InterPro protein domains (see all 7):
     IPR001965 Znf_PHD
     IPR013083 Znf_RING/FYVE/PHD
     IPR002857 Znf_CXXC
     IPR001810 F-box_dom
     IPR019786 Zinc_finger_PHD-type_CS

    Graphical View of Domain Structure for InterPro Entry Q6PCT2

    ProtoNet protein and cluster: Q6PCT2

    UniProtKB/Swiss-Prot: FXL19_HUMAN, Q6PCT2
    Similarity: Contains 1 CXXC-type zinc finger
    Similarity: Contains 1 F-box domain
    Similarity: Contains 6 LRR (leucine-rich) repeats
    Similarity: Contains 1 PHD-type zinc finger


    Find genes that share domains with FBXL19           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FXL19_HUMAN, Q6PCT2
    Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex
    (By similarity)

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
         
    Find genes that share ontologies with FBXL19           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for FBXL19:
     Low eccentricity cells 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for FBXL19

    miRNA
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    miRTarBase miRNAs that target FBXL19:
    hsa-mir-193b-3p (MIRT041349), hsa-mir-92a-3p (MIRT049576), hsa-mir-423-3p (MIRT042632), hsa-mir-615-3p (MIRT040201), hsa-mir-744-5p (MIRT037597)

    Block miRNA regulation of human, mouse, rat FBXL19 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FBXL19 (see all 59):
    hsa-let-7d hsa-miR-765 hsa-miR-200a hsa-miR-1260b hsa-let-7a-2* hsa-miR-3074-3p hsa-miR-138-2* hsa-let-7g
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Predesigned siRNA for gene silencing in human, mouse, rat FBXL19

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0019005SCF ubiquitin ligase complex IDA--

    Find genes that share ontologies with FBXL19           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FBXL19
    Interactions:

        Search GeneGlobe Interaction Network for FBXL19

    STRING Interaction Network Preview (showing 5 interactants - click image to see 21)

    Selected Interacting proteins for FBXL19 (Q6PCT23 ENSP000003696664) via UniProtKB, MINT, STRING, and/or I2D (see all 26)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000215641P143733I2D: score=1 
    ENSG00000229006P143733I2D: score=1 
    ENSG00000234495P143733I2D: score=1 
    ENSG00000237071P143733I2D: score=1 
    TRIM27P143733I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process IDA--

    Find genes that share ontologies with FBXL19           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FBXL19 (FXL19)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for FBXL19 gene (4 alternative transcripts): 
    NM_001099784.2  NM_001282351.1  NM_001271651.1  NM_019085.1  

    Unigene Cluster for FBXL19:

    F-box and leucine-rich repeat protein 19
    Hs.152149  [show with all ESTs]
    Unigene Representative Sequence: NM_001099784
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000562798 ENST00000471231(uc002dzz.1) ENST00000338343 ENST00000562319
    ENST00000565690 ENST00000427128 ENST00000566320 ENST00000565939 ENST00000380310(uc002eab.2 uc002eaa.1)

    miRNA
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    Block miRNA regulation of human, mouse, rat FBXL19 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FBXL19 (see all 59):
    hsa-let-7d hsa-miR-765 hsa-miR-200a hsa-miR-1260b hsa-let-7a-2* hsa-miR-3074-3p hsa-miR-138-2* hsa-let-7g
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Predesigned siRNA for gene silencing in human, mouse, rat FBXL19
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    GenScript: all cDNA clones in your preferred vector: FBXL19 (NM_001099784)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FBXL19
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for FBXL19
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FBXL19
      QuantiTect SYBR Green Assays in human, mouse, rat FBXL19
      QuantiFast Probe-based Assays in human, mouse, rat FBXL19

    Additional mRNA sequence: 

    AK127701.1 AK302669.1 AL137589.1 BC032391.1 BC048811.1 BC059173.1 NR_073401.1 

    4 DOTS entries:

    DT.40261115  DT.95110062  DT.70103185  DT.87011836 

    Selected AceView cDNA sequences (see all 186):

    BC048811 AW444819 BM129511 AA862341 AA423891 BM764400 BQ648716 AA515878 
    BM680919 AL137589 AI280701 BE222694 C01878 BX384015 BX111140 AI289104 
    NM_019085 CA412795 AI702473 BC059173 BM904282 AK127701 BU608652 BQ574949 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for FBXL19 (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12
    SP1:              -     -                                                                                                   
    SP2:                                                                          -                                             
    SP3:                                                                                                                        
    SP4:                                                                                                                        
    SP5:                                                                                                        -               


    ECgene alternative splicing isoforms for FBXL19

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FBXL19 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAGGGGAGGG
    FBXL19 Expression
    About this image

    FBXL19 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FBXL19 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.152149
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for FBXL19 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fbxl191 , 5 F-box and leucine-rich repeat protein 191, 5 89.66(n)1
    97.48(a)1
      7 (69.71 cM)5
    2339021  NM_172748.21  NP_766336.21 
     1277467755 
    lizard
    (Anolis carolinensis)
    Reptilia FBXL196
    F-box and leucine-rich repeat protein 19
    66(a)
    1 ↔ 1
    GL343220.1(1809604-1833799)
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1583761 zgc:158376 64.44(n)
    61.73(a)
      100101643  NM_001100147.1  NP_001093617.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Kdm26
    Lysine (K)-specific demethylase 2
    13(a)
    1 → many
    3R(4878240-4888967)
    worm
    (Caenorhabditis elegans)
    Secernentea jhdm-16
    Protein JHDM-1, isoform a
    8(a)
    1 → many
    III(6454483-6460010) WBGene00020821
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes JHD16
    JmjC domain family histone demethylase specific fo...
    1(a)
    1 → many
    V(254656-256134) YER051W


    ENSEMBL Gene Tree for FBXL19 (if available)
    TreeFam Gene Tree for FBXL19 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FBXL19 gene
    PHF22  PHF82  KDM2A2  KDM7A2  KDM2B2  
    3 SIMAP similar genes for FBXL19 using alignment to 8 protein entries:     FXL19_HUMAN (see all proteins):
    CXXC1    KDM2A    KDM2B

    Find genes that share paralogs with FBXL19           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FBXL19 (see all 337)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs727993411,2
    C,F--30936743(+) AAGGAG/ACTCCG 3 -- int15Minor allele frequency- A:0.12NA CSA WA EA 362
    rs1496200871,2
    C--30937144(+) TGCCGG/TGCCTG 5 R syn10--------
    rs1807451181,2
    C--30937201(+) AAGTTC/TGGGGG 5 F syn10--------
    rs1449048011,2
    C--30937348(+) TGGCT-/GGGGG 
            
    GTTTG
    3 -- int10--------
    rs747666021,2
    C--30937350(+) GGCTGG/TTTGTT 3 -- int10--------
    rs80505881,2
    C,F,A,H--30937799(+) GGATCG/AGGGAA 3 -- int123Minor allele frequency- A:0.42NS EA NA WA CSA 2348
    rs1120512301,2
    F--30938055(+) GATCCC/TGCCGC 3 -- int11Minor allele frequency- T:0.50CSA 2
    rs791348831,2
    C--30938126(+) CCCCAC/TTTCCC 3 -- int11Minor allele frequency- T:0.01NA 120
    rs1898241131,2
    --30938358(+) CTACAC/TATCAG 3 -- int10--------
    rs1471518111,2
    C--30938544(+) CATCCA/GTCACC 3 -- int10--------

    HapMap Linkage Disequilibrium report for FBXL19 (30934376 - 30960104 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for FBXL19:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv35n68CNV Loss17160897
    nsv833189CNV Loss17160897
    nsv905738CNV Loss21882294
    nsv457483CNV Loss19166990
    dgv2671n71CNV Loss21882294
    nsv905729CNV Loss21882294
    nsv905733CNV Loss21882294
    dgv2670n71CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609085    OMIM disorders: --

    1 disease for FBXL19:    
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    psoriasis

    1 disease from the University of Copenhagen DISEASES database for FBXL19:
    Psoriatic arthritis

    Find genes that share disorders with FBXL19           About GenesLikeMe

    Genetic Association Database (GAD): FBXL19
    Human Genome Epidemiology (HuGE) Navigator: FBXL19 (1 document)

    Export disorders for FBXL19 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FBXL19 gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with FBXL19)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genome-wide association analysis identifies three psoriasis susceptibility loci. (PubMed id 20953189)1, 4 Stuart P.E....Elder J.T. (Nat. Genet. 2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. The genetics of psoriasis and psoriatic arthritis. (PubMed id 22274791)1 Chandran V. (amp 2013)
    5. Parallel SCF adaptor capture proteomics reveals a role for SCFFBXL17 in NRF2 activation via BACH1 repressor turnover. (PubMed id 24035498)1 Tan M.K....Harper J.W. (Mol. Cell 2013)
    6. F-box protein FBXL19-mediated ubiquitination and degradation of the receptor for IL-33 limits pulmonary inflammation. (PubMed id 22660580)1 Zhao J....Zhao Y. (Nat. Immunol. 2012)
    7. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    8. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (Cell 2010)
    9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Aliases
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      Query String
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    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54620 HGNC: 25300 AceView: FBXL19andMGC13024 Ensembl:ENSG00000099364 euGenes: HUgn54620
    ECgene: FBXL19 H-InvDB: FBXL19

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for FBXL19 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for FBXL19 gene:
    Search GeneIP for patents involving FBXL19

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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