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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FBXL17 Gene

protein-coding   GIFtS: 44
GCID: GC05M107223

F-box and leucine-rich repeat protein 17

(Previous name: F-box only protein 13 )
(Previous symbol: FBXO13)
 Explore 1 disease affiliated with
FBXL17 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for FBXL17    

Aliases
for FBXL17 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
F-Box And Leucine-Rich Repeat Protein 171 2 3     FBL173 5
FBXO131 2 3 5     FBX133 5
F-Box Only Protein 131 2 3     DKFZP434C17151
Fbl171 2     F-Box/LRR-Repeat Protein 172
Fbx131 2     

External Ids:    HGNC: 136151   Entrez Gene: 648392   Ensembl: ENSG000001457437   OMIM: 6090835   UniProtKB: Q9UF563   

Export aliases for FBXL17 gene to outside databases

Previous GC identifers: GC05M107271 GC05M102367


Summaries
for FBXL17 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for FBXL17:
Members of the F-box protein family, such as FBXL17, are characterized by an approximately 40-amino acid F-box motif.
SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as
protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination
targets through other protein interaction domains (Jin et al., 2004 (PubMed 15520277)).(supplied by OMIM, Mar 2008)

UniProtKB/Swiss-Prot: FXL17_HUMAN, Q9UF56
Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex (By
similarity)




Genomic Views
for FBXL17 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.1  NT_034772.6  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FBXL17 gene promoter:
         c-Fos   AREB6   Elk-1   AP-1   Sp1   COMP1   c-Jun   Ik-3   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: FBXL17 promoter sequence
   Search SABiosciences Chromatin IP Primers for FBXL17

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FBXL17


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q21.3   Ensembl cytogenetic band:  5q21.3   HGNC cytogenetic band: 5q21.3

FBXL17 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FBXL17 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M107223:  view genomic region     (about GC identifiers)

Start:
 107,194,734 bp from pter      End:
 107,717,799 bp from pter
Size:
 523,066 bases      Orientation:
 minus strand

Proteins
for FBXL17 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: FXL17_HUMAN, Q9UF56 (See protein sequence)
Recommended Name: F-box/LRR-repeat protein 17  
Size: 701 amino acids; 75695 Da
Subunit: Interacts with SKP1 and CUL1 (By similarity)
Secondary accessions: A1A4E3
Alternative splicing: 3 isoforms:  Q9UF56-1   Q9UF56-3   Q9UF56-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FBXL17: NX_Q9UF56

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UF56

    • FBXL17 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001156787.2  
    ENSEMBL proteins: 
     ENSP00000352683   ENSP00000418111   ENSP00000437464  

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    Novus Biologicals FBXL17 Lysates
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    Uscn Proteins for FBXL17


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    Uscn ELISAs and CLIAs for FBXL17

    Protein Domains /
    Families
    for FBXL17 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    FBXL17 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR001810 F-box_dom_cyclin-like

    Graphical View of Domain Structure for InterPro Entry Q9UF56

    ProtoNet protein and cluster: Q9UF56

    UniProtKB/Swiss-Prot: FXL17_HUMAN, Q9UF56
    Similarity: Contains 1 F-box domain


    Function
    for FBXL17 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: FXL17_HUMAN, Q9UF56
    Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex (By
    similarity)

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FBXL17
    8/48 QIAGEN miScript miRNA Assays for microRNAs that regulate FBXL17 (see all 48):
    hsa-miR-429 hsa-miR-4272 hsa-miR-25 hsa-miR-30d hsa-miR-219-5p hsa-miR-519a hsa-miR-1304 hsa-miR-30a
    SwitchGear 3'UTR luciferase reporter plasmid: FBXL17 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FBXL17 (see all 4)
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    Cell Line
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    Search LifeMap BioReagents cell lines for FBXL17

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FBXL17

    3 GenomeRNAi human phenotypes for FBXL17:
     Decreased viability with pacli  G0/1 arrest  Increased G1 DNA content 


    Pathways & Interactions
    for FBXL17 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FBXL17

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for FBXL17 (ENSP000004181114) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SIRT1ENSP000002120154STRING: ENSP00000212015
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Drugs & Compounds
    for FBXL17 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FBXL17
    Search CenterWatch for drugs/clinical trials and news about FBXL17 / FXL17 

    Transcripts
    for FBXL17 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for FBXL17 gene (2 alternative transcripts): 
    NM_022824.1  NM_001163315.2  

    Unigene Cluster for FBXL17:

    F-box and leucine-rich repeat protein 17
    Hs.657225  [show with all ESTs]
    Unigene Representative Sequence: NM_001163315
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000359660 ENST00000496714(uc003kon.4) ENST00000481160 ENST00000518486
    ENST00000542267(uc011cvc.2)

    miRNA
    Products:             		 OriGene 3'-UTR Clone: FBXL17
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FBXL17
    8/48 QIAGEN miScript miRNA Assays for microRNAs that regulate FBXL17 (see all 48):
    hsa-miR-429 hsa-miR-4272 hsa-miR-25 hsa-miR-30d hsa-miR-219-5p hsa-miR-519a hsa-miR-1304 hsa-miR-30a
    SwitchGear 3'UTR luciferase reporter plasmid: FBXL17 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FBXL17 (see all 4)
    OriGene shRNA RFP: FBXL17
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    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FBXL17
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FBXL17

    Additional cDNA sequence: 

    AB533280.1 AK126722.1 AK172822.1 AL133602.1 BC018548.2 BC126144.1 BC126146.1 

    5 DOTS entries:

    DT.452070  DT.95219556  DT.92042073  DT.40259668  DT.91752406 

    24/71 AceView cDNA sequences (see all 71):

    AA687884 AW002313 AI127909 H93512 BM720801 BM676904 BC018548 AA804434 
    BM023593 BM021542 AA988642 BM353053 AA605275 AA532453 BM677076 AW630872 
    BF437214 BX487603 AI359105 CB242339 BF531122 BU167043 N34057 BE379607 

    GeneLoc Exon Structure


    Expression
    for FBXL17 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FBXL17 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TGAACACGTT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    FBXL17 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    3 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Spinal CordSpinal Ventral ColumnsVentral Spinal Cord Progenitor CellsMotor Neurons
    Neural TubeMesencephalic Ventricular ZoneNeural Tube
    Spinal CordSpinal Ventral ColumnsSpinal Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See FBXL17 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FBXL17

    SOURCE GeneReport for Unigene cluster: Hs.657225
        SABiosciences Custom PCR Arrays for FBXL17
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FBXL17

    Orthologs
    for FBXL17 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for FBXL17 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Fbxl171 , 5 F-box and leucine-rich repeat protein 171, 5 91.22(n)1
    93.96(a)1    		   17 (32.68 cM)5
    507581  NM_015794.11  NP_056609.11 
     630574525 
    chicken
    (Gallus gallus)    		 Aves FBXL171 F-box and leucine-rich repeat protein 17 78.58(n)
    78.58(a)    		   415615  XM_413983.3  XP_413983.3 
    lizard
    (Anolis carolinensis)    		 Reptilia FBXL176
    		 --
    		 90(a)
    		 1 ↔ 1
    		 GL343193.1(4971179-5043709)
    zebrafish
    (Danio rerio)    		 Actinopterygii LOC7950231 f-box/LRR-repeat protein 17-like 58.56(n)
    54.6(a)    		   795023  XM_001335061.4  XP_001335097.4 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT2G170206
    AT1G555906
    		 F-box protein At-B
    		 9(a)
    10(a)
    		 many ↔ many
    many ↔ many
    		 2(7396337-7398838)
    1(20769320-20771871)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    		 F-box protein At-B, putative, expressed
    OsFBL10 - F-box domain and LRR containing protein,...
    		 11(a)
    11(a)
    		 many ↔ many
    many ↔ many
    		 8(24674869-24677686)
    3(1955855-1958795)


    ENSEMBL Gene Tree for FBXL17 (if available)
    TreeFam Gene Tree for FBXL17 (if available) 

    Paralogs
    for FBXL17 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FBXL17 gene
    FBXL22  FBXL202  ENSG000002371022  FBXL132  FBXL162  FBXL72  AMN12  LRRC292  
    FBXL152  FBXL42  FBXL142  

    FBXL17 for paralogs           About GeneDecksing



    Genomic Variants
    for FBXL17 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/9040 NCBI SNPs in FBXL17 are shown (see all 9040)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 5 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1883493581,2
    		--107194237(+) CGTGTC/TGTGGG 1 -- int10--------
    rs1913029711,2
    		--107194242(+) CGTGGA/GAGGGA 1 -- int10--------
    rs1138450951,2
    		C,--107194259(+) GGGAGG/CCAATG 1 -- int14Minor allele frequency- C:0.12NA WA EA 360
    rs1399009861,2
    		--107194270(+) GAATCA/TTGGGG 1 -- int10--------
    rs1832160621,2
    		--107194360(+) TGCTTC/GGTTCT 1 -- int10--------
    rs1438322011,2
    		--107194388(+) CCACCC/TTGTGA 1 -- int10--------
    rs1474420891,2
    		--107194417(+) TCCCTC/TCTGCC 1 -- int10--------
    rs1876619931,2
    		--107194490(+) GTATAA/CCCTTT 1 -- int10--------
    rs1397240031,2
    		--107194618(+) GTTAGA/TCAAAC 1 -- int10--------
    rs753997081,2
    		C,--107194689(+) CAGCAT/CTGGGG 1 -- int14Minor allele frequency- C:0.11NA WA EA 360

    HapMap Linkage Disequilibrium report for FBXL17 (107194734 - 107444734 bp, first 250kb of FBXL17)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 7 variations for FBXL17
         4 CNVs: 6434 36331 99248 99247
         3 Indels: 46744 64270 40791

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FBXL17
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    Disorders / Diseases
    for FBXL17 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    FBXL17 for disorders           About GeneDecksing

    OMIM gene information: 609083    OMIM disorders: --

    1 disease for FBXL17:    About MalaCards
    breast cancer

    Human Genome Epidemiology (HuGE) Navigator: FBXL17 (2 documents)

    Export disorders for FBXL17 gene to outside databases

    Publications
    for FBXL17 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FBXL17 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with FBXL17)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    2. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
    3. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    5. Replication of previous genome-wide association studi es of bone mineral density in premenopausal American women. (PubMed id 20200978)1 Ichikawa S....Econs M.J. (2010)
    6. Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
    7. Identification of F-box/LLR-repeated protein 17 as potential useful biomarker for breast cancer therapy. (PubMed id 18820369)1 Xiao G.G....Yen Y. (2008)
    8. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    10. The DNA sequence and comparative analysis of human chromosome 5. (PubMed id 15372022)2 Schmutz J.... Rubin E.M. (2004)

    External Searches for FBXL17 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
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    Genome Databases showing FBXL17 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 64839 HGNC: 13615 AceView: FBXL17 Ensembl:ENSG00000145743 euGenes: HUgn64839
    ECgene: FBXL17 H-InvDB: FBXL17

    Other Databases showing FBXL17 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing FBXL17 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FBXL17 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for FBXL17 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for FBXL17 gene:
    Search GeneIP for patents involving FBXL17

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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