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FBXL14 Gene

protein-coding   GIFtS: 48
GCID: GC12M001675

F-Box And Leucine-Rich Repeat Protein 14

  Search for FBXL14
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
F-Box And Leucine-Rich Repeat Protein 141 2 3
FBL143 5
Fbl142
F-Box/LRR-Repeat Protein 142

External Ids:    HGNC: 286241   Entrez Gene: 1446992   Ensembl: ENSG000001718237   OMIM: 6090815   UniProtKB: Q8N1E63   

Export aliases for FBXL14 gene to outside databases

Previous GC identifers: GC12M001546 GC12M001547 GC12M001549


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for FBXL14 Gene:
Members of the F-box protein family, such as FBXL14, are characterized by an approximately 40-amino acid F-box
motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as
protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with
ubiquitination targets through other protein interaction domains (Jin et al., 2004 (PubMed 15520277)).(supplied
by OMIM, Mar 2008)

GeneCards Summary for FBXL14 Gene:
FBXL14 (F-box and leucine-rich repeat protein 14) is a protein-coding gene. GO annotations related to this gene include ubiquitin-protein ligase activity. An important paralog of this gene is FBXL2.

UniProtKB/Swiss-Prot: FXL14_HUMAN, Q8N1E6
Function: Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin-protein ligase
complexes. The SCF(FBXL14) complex acts by mediating ubiquitination and subsequent degradation of SNAI1




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000012.12  NC_018923.2  NT_009759.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the FBXL14 gene promoter:
         AhR   MyoD   C/EBPalpha   Arnt   c-Ets-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFBXL14 promoter sequence
   Search Chromatin IP Primers for FBXL14

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FBXL14


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p13.33   Ensembl cytogenetic band:  12p13.33   HGNC cytogenetic band: 12p13.33

FBXL14 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FBXL14 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M001675:  view genomic region     (about GC identifiers)

Start:
1,675,159 bp from pter      End:
1,703,331 bp from pter
Size:
28,173 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: FXL14_HUMAN, Q8N1E6 (See protein sequence)
Recommended Name: F-box/LRR-repeat protein 14  
Size: 418 amino acids; 45886 Da
Subunit: Part of a SCF (SKP1-cullin-F-box) ubiquitin-protein ligase complex. Interacts with SKP1 and CUL1 (By
similarity). Interacts with SNAI1; the interaction requires the phosphorylation of the two serine residues in the
substrate destruction motif D-S-G-X(2,3,4)-S

Explore the universe of human proteins at neXtProt for FBXL14: NX_Q8N1E6

Explore proteomics data for FBXL14 at MOPED


See FBXL14 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_689654.1  
ENSEMBL proteins: 
 ENSP00000344855  

FBXL14 Human Recombinant Protein Products:

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LSBio Antibodies in human, mouse, rat for FBXL14

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Cloud-Clone Corp. CLIAs for FBXL14
Search eBioscience for ELISAs for FBXL14 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
FBXL: F-boxes / Leucine-rich repeats

3 InterPro protein domains:
 IPR001611 Leu-rich_rpt
 IPR013101 Leu-rich_rpt_2
 IPR001810 F-box_dom

Graphical View of Domain Structure for InterPro Entry Q8N1E6

ProtoNet protein and cluster: Q8N1E6

UniProtKB/Swiss-Prot: FXL14_HUMAN, Q8N1E6
Similarity: Contains 1 F-box domain
Similarity: Contains 5 LRR (leucine-rich) repeats


Find genes that share domains with FBXL14           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: FXL14_HUMAN, Q8N1E6
Function: Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin-protein ligase
complexes. The SCF(FBXL14) complex acts by mediating ubiquitination and subsequent degradation of SNAI1
Induction: Down-regulated by hypoxia

     Gene Ontology (GO): 2 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0004842ubiquitin-protein ligase activity IDA19955572
GO:0005515protein binding IPI19955572
     
Find genes that share ontologies with FBXL14           About GenesLikeMe


Phenotypes:
     1 GenomeRNAi human phenotype for FBXL14:
 Synthetic lethal with paclitax 

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FBXL14
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FBXL14

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FBXL14
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FBXL14

miRNA
Products:
    
miRTarBase miRNAs that target FBXL14:
hsa-mir-615-3p (MIRT040331)

Block miRNA regulation of human, mouse, rat FBXL14 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate FBXL14 (see all 20):
hsa-miR-30c hsa-miR-30d hsa-miR-1257 hsa-miR-3171 hsa-miR-3150a-3p hsa-miR-4267 hsa-miR-30a hsa-miR-23a
SwitchGear 3'UTR luciferase reporter plasmidFBXL14 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for FBXL14
Predesigned siRNA for gene silencing in human, mouse, rat FBXL14

Gene Editing
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Sino Biological Human cDNA Clone for FBXL14
DNA2.0 Custom Codon Optimized Gene Synthesis Service for FBXL14
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FBXL14

Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FBXL14


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
FXL14_HUMAN, Q8N1E6: Cytoplasm
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
cytosol2
extracellular1
mitochondrion1
nucleus1
peroxisome1

Gene Ontology (GO): 4 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IDA--
GO:0005730NOT nucleolus IDA--
GO:0005737cytoplasm IDA--
GO:0005794Golgi apparatus IDA--

Find genes that share ontologies with FBXL14           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Pathway & Disease-focused RT2 Profiler PCR Array including FBXL14: 
          Ubiquitin Ligases in human mouse rat

Interactions:

    Search GeneGlobe Interaction Network for FBXL14

STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

Selected Interacting proteins for FBXL14 (Q8N1E63 ENSP000003448554) via UniProtKB, MINT, STRING, and/or I2D (see all 15)
InteractantInteraction Details
GeneCardExternal ID(s)
SNAI1O958633, ENSP000002440504I2D: score=1 STRING: ENSP00000244050
XPCENSP000002850214STRING: ENSP00000285021
POLR2IENSP000002218594STRING: ENSP00000221859
SUPT4H1ENSP000002255044STRING: ENSP00000225504
ERCC6ENSP000003480894STRING: ENSP00000348089
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Gene Ontology (GO): 1 biological process term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic process IDA19955572

Find genes that share ontologies with FBXL14           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for FBXL14 (FXL14)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for FBXL14 gene: 
NM_152441.2  

Unigene Cluster for FBXL14:

F-box and leucine-rich repeat protein 14
Hs.367956  [show with all ESTs]
Unigene Representative Sequence: BC028132
2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000339235(uc001qjh.3) ENST00000543278
miRNA
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Block miRNA regulation of human, mouse, rat FBXL14 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate FBXL14 (see all 20):
hsa-miR-30c hsa-miR-30d hsa-miR-1257 hsa-miR-3171 hsa-miR-3150a-3p hsa-miR-4267 hsa-miR-30a hsa-miR-23a
SwitchGear 3'UTR luciferase reporter plasmidFBXL14 3' UTR sequence
Inhib. RNA
Products:
     
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Predesigned siRNA for gene silencing in human, mouse, rat FBXL14
Clone
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OriGene ORF clones in mouse, rat for FBXL14
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: FBXL14 (NM_152441)
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FBXL14
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for FBXL14
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FBXL14
  QuantiTect SYBR Green Assays in human, mouse, rat FBXL14
  QuantiFast Probe-based Assays in human, mouse, rat FBXL14

Additional mRNA sequence: 

AF007128.1 BC028132.1 

5 DOTS entries:

DT.214954  DT.214953  DT.100745704  DT.40225682  DT.99952826 

Selected AceView cDNA sequences (see all 130):

BQ720804 AI373728 F09498 BF359741 BF590969 BM127210 BE501360 CA307050 
BM053067 AW134908 BX099769 CR589998 BU738298 BU623062 BM127496 AI472033 
U25905 AI458123 AA334373 AI339835 BQ008899 BM675576 AI340145 BM563374 

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for FBXL14    About this scheme

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b
SP1:                          -               
SP2:                    -     -               
SP3:                    -                     


ECgene alternative splicing isoforms for FBXL14

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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FBXL14 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GAGTTAAAGA
FBXL14 Expression
About this image

FBXL14 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

FBXL14 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.367956
    Pathway & Disease-focused RT2 Profiler PCR Array including FBXL14: 
          Ubiquitin Ligases in human mouse rat

Primer
Products:
OriGene qSTAR qPCR primer pairs in human, mouse for FBXL14
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FBXL14
QuantiTect SYBR Green Assays in human, mouse, rat FBXL14
QuantiFast Probe-based Assays in human, mouse, rat FBXL14
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FBXL14

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for FBXL14 gene from Selected species (see all 14)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Fbxl141 , 5 F-box and leucine-rich repeat protein 141, 5 94.47(n)1
100(a)1
  6 (56.86 cM)5
1013581  NM_133940.31  NP_598701.21 
 1194796685 
chicken
(Gallus gallus)
Aves FBXL141 F-box and leucine-rich repeat protein 14 87.78(n)
95.15(a)
  427926  XM_003640416.2  XP_003640464.2 
lizard
(Anolis carolinensis)
Reptilia FBXL146
F-box and leucine-rich repeat protein 14
94(a)
1 ↔ 1
5(12711270-12711833)
African clawed frog
(Xenopus laevis)
Amphibia AF176354.12   -- 82.74(n)    AF176354.1 
zebrafish
(Danio rerio)
Actinopterygii ppab2 partner of paired b 81.11(n)   324835  AF467462.1 
fruit fly
(Drosophila melanogaster)
Insecta ppa1 partner of paired 62.81(n)
63.24(a)
  37602  NM_079088.2  NP_523812.1 


ENSEMBL Gene Tree for FBXL14 (if available)
TreeFam Gene Tree for FBXL14 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for FBXL14 gene
FBXL22  FBXL172  FBXL202  ENSG000002371022  FBXL132  FBXL162  FBXL72  LRRC292  
FBXL152  FBXL42  
1 SIMAP similar gene for FBXL14 using alignment to 1 protein entry:     FXL14_HUMAN:
FBXL2

Find genes that share paralogs with FBXL14           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for FBXL14 (see all 759)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 12 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1429116591,2
C--1674692(+) TTCTTC/TGGACT 1 -- ds50010--------
rs755714091,2
C,F--1674752(+) TGAGAG/ATTTCA 1 -- ds50011Minor allele frequency- A:0.05EA 120
rs1932021891,2
--1674774(+) TGACAA/GGGTAA 1 -- ds50010--------
rs768335671,2
C--1674801(+) CAGGAA/GTTGTA 1 -- ds50012Minor allele frequency- G:0.07CSA EA 122
rs1830553071,2
--1674852(+) CTTGAC/GATGTG 1 -- ds50010--------
rs736058661,2
C,F--1674853(+) TTGACA/CTGTGC 1 -- ds50013Minor allele frequency- C:0.15WA 122
rs1510723261,2
C--1674884(+) CTTCAC/TTGATC 1 -- ds50010--------
rs1168690411,2
C,F--1675076(+) GATCCG/AGTTTA 1 -- ds50011Minor allele frequency- A:0.01NA 120
rs1176555831,2
F--1675089(+) TTACAA/GAACCA 1 -- ds50011Minor allele frequency- G:0.01EA 120
rs2022024141,2
C--1675131(+) AGAGA-/GA/GAG
A
/GAGAGA
ACAAG
2 -- ds5001 cds10--------

HapMap Linkage Disequilibrium report for FBXL14 (1675159 - 1703331 bp)

Structural Variations
     Database of Genomic Variants (DGV) 8 variations for FBXL14:    About this table    
Variant IDTypeSubtypePubMed ID
esv2658521CNV Deletion23128226
esv1766777CNV Insertion17803354
esv1091719CNV Insertion17803354
esv27885CNV Loss19812545
nsv470258CNV Gain18288195
nsv898586CNV Gain21882294
dgv257n67CNV Gain20364138
nsv898584CNV Gain21882294

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing FBXL14
DNA2.0 Custom Variant and Variant Library Synthesis for FBXL14

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 609081    OMIM disorders: --


Find genes that share disorders with FBXL14           About GenesLikeMe


Export disorders for FBXL14 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for FBXL14 gene integrated from 10 sources:
(articles sorted by number of sources associating them with FBXL14)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The hypoxia-controlled FBXL14 ubiquitin ligase targets SNAIL1 for proteasome degradation. (PubMed id 19955572)1, 2 Vinas-Castells R....Diaz V.M. (J. Biol. Chem. 2010)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  4. Parallel SCF adaptor capture proteomics reveals a role for SCFFBXL17 in NRF2 activation via BACH1 repressor turnover. (PubMed id 24035498)1 Tan M.K....Harper J.W. (Mol. Cell 2013)
  5. Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. (PubMed id 22939624)1 Taipale M....Lindquist S. (Cell 2012)
  6. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
  7. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
  8. Systematic analysis and nomenclature of mammalian F-box proteins. (PubMed id 15520277)1 Jin J....Harper J.W. (Genes Dev. 2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 144699 HGNC: 28624 AceView: FBXL14 Ensembl:ENSG00000171823 euGenes: HUgn144699
ECgene: FBXL14 H-InvDB: FBXL14

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for FBXL14 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for FBXL14 gene:
Search GeneIP for patents involving FBXL14

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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