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Aliases for FBRSL1 Gene

Aliases for FBRSL1 Gene

  • Fibrosin-Like 1 2 3
  • HBV X-Transactivated Gene 9 Protein 4
  • HBV XAg-Transactivated Protein 9 4
  • AUTS2-Like Protein 4
  • KIAA1545 4
  • AUTS2L 4
  • XTP9 4

External Ids for FBRSL1 Gene

Previous GeneCards Identifiers for FBRSL1 Gene

  • GC12P131578
  • GC12P133067
  • GC12P129866

Summaries for FBRSL1 Gene

GeneCards Summary for FBRSL1 Gene

FBRSL1 (Fibrosin-Like 1) is a Protein Coding gene. An important paralog of this gene is FBRS.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FBRSL1 Gene

Genomics for FBRSL1 Gene

Regulatory Elements for FBRSL1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FBRSL1 Gene

132,489,551 bp from pter
132,585,188 bp from pter
95,638 bases
Plus strand

Genomic View for FBRSL1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FBRSL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FBRSL1 Gene

Proteins for FBRSL1 Gene

  • Protein details for FBRSL1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Fibrosin-1-like protein
    Protein Accession:
    Secondary Accessions:
    • Q86XQ1

    Protein attributes for FBRSL1 Gene

    1045 amino acids
    Molecular mass:
    110907 Da
    Quaternary structure:
    No Data Available
    • Sequence=EAW54843.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for FBRSL1 Gene

Proteomics data for FBRSL1 Gene at MOPED

Post-translational modifications for FBRSL1 Gene

  • Ubiquitination at Lys484
  • Modification sites at PhosphoSitePlus

Other Protein References for FBRSL1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FBRSL1 Gene

Domains for FBRSL1 Gene

Protein Domains for FBRSL1 Gene


Suggested Antigen Peptide Sequences for FBRSL1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the AUTS2 family.
  • Belongs to the AUTS2 family.
genes like me logo Genes that share domains with FBRSL1: view

No data available for Gene Families for FBRSL1 Gene

Function for FBRSL1 Gene

Gene Ontology (GO) - Molecular Function for FBRSL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0044822 poly(A) RNA binding IDA 22681889
genes like me logo Genes that share ontologies with FBRSL1: view

miRNA for FBRSL1 Gene

miRTarBase miRNAs that target FBRSL1

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FBRSL1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for FBRSL1 Gene

Localization for FBRSL1 Gene

Subcellular locations from

Jensen Localization Image for FBRSL1 Gene COMPARTMENTS Subcellular localization image for FBRSL1 gene
Compartment Confidence
nucleus 3
cytosol 2
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FBRSL1 Gene

Pathways for FBRSL1 Gene

SuperPathways for FBRSL1 Gene

No Data Available

Interacting Proteins for FBRSL1 Gene

Gene Ontology (GO) - Biological Process for FBRSL1 Gene


No data available for Pathways by source for FBRSL1 Gene

Transcripts for FBRSL1 Gene

Unigene Clusters for FBRSL1 Gene

Fibrosin-like 1:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FBRSL1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FBRSL1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16

Relevant External Links for FBRSL1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FBRSL1 Gene

mRNA expression in normal human tissues for FBRSL1 Gene

Protein differential expression in normal tissues for FBRSL1 Gene

This gene is overexpressed in Salivary gland (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for FBRSL1 Gene

SOURCE GeneReport for Unigene cluster for FBRSL1 Gene Hs.411138

genes like me logo Genes that share expressions with FBRSL1: view

Expression partners for FBRSL1 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FBRSL1 Gene

Orthologs for FBRSL1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for FBRSL1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FBRSL1 35
  • 82.06 (n)
  • 77.45 (a)
  • 64 (a)
(Canis familiaris)
Mammalia FBRSL1 35
  • 79.18 (n)
  • 74.38 (a)
  • 63 (a)
(Mus musculus)
Mammalia Fbrsl1 35
  • 79.36 (n)
  • 75.84 (a)
Fbrsl1 16
Fbrsl1 36
  • 60 (a)
(Pan troglodytes)
Mammalia FBRSL1 35
  • 98.85 (n)
  • 98.28 (a)
  • 98 (a)
(Rattus norvegicus)
Mammalia Fbrsl1 35
  • 79.1 (n)
  • 75.73 (a)
(Monodelphis domestica)
Mammalia FBRSL1 36
  • 55 (a)
(Ornithorhynchus anatinus)
Mammalia FBRSL1 36
  • 45 (a)
(Gallus gallus)
Aves FBRSL1 36
  • 43 (a)
(Anolis carolinensis)
Reptilia FBRSL1 36
  • 40 (a)
(Danio rerio)
Actinopterygii fbrsl1 36
  • 39 (a)
Species with no ortholog for FBRSL1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FBRSL1 Gene

Gene Tree for FBRSL1 (if available)
Gene Tree for FBRSL1 (if available)

Paralogs for FBRSL1 Gene

Paralogs for FBRSL1 Gene Pseudogenes for FBRSL1 Gene

genes like me logo Genes that share paralogs with FBRSL1: view

Variants for FBRSL1 Gene

Sequence variations from dbSNP and Humsavar for FBRSL1 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs10870461 -- 132,531,634(+) tgcac(A/T)tggcg intron-variant
rs10870464 -- 132,540,903(+) AAGTT(A/C)TTTCC intron-variant
rs10870465 -- 132,548,889(+) TTCTC(A/G)CCCTG intron-variant
rs10870469 -- 132,566,100(+) agttc(C/T)gcagc intron-variant
rs10870471 -- 132,573,723(+) GGCGC(C/G)CCTGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FBRSL1 Gene

Variant ID Type Subtype PubMed ID
dgv1520n71 CNV Loss 21882294
nsv826563 CNV Gain 20364138
nsv899765 CNV Loss 21882294
dgv1531n71 CNV Loss 21882294
nsv509494 CNV Insertion 20534489
dgv1533n71 CNV Loss 21882294
dgv1534n71 CNV Loss 21882294
nsv899780 CNV Loss 21882294
dgv1535n71 CNV Loss 21882294
dgv1536n71 CNV Loss 21882294
nsv899785 CNV Loss 21882294
dgv1537n71 CNV Loss 21882294
nsv470334 CNV Loss 18288195
dgv1538n71 CNV Gain+Loss 21882294
nsv899798 CNV Gain 21882294
esv2747002 CNV Deletion 23290073
esv2678329 CNV Deletion 23128226
esv2747003 CNV Deletion 23290073
esv2407620 CNV Deletion 18987734
esv2747004 CNV Deletion 23290073
esv991918 CNV Deletion 20482838
esv1553523 CNV Deletion 17803354
esv29631 CNV Loss 19812545
dgv1539n71 CNV Loss 21882294
dgv1540n71 CNV Loss 21882294
nsv455806 CNV Loss 19166990
nsv455807 CNV Loss 19166990
dgv1541n71 CNV Loss 21882294
esv2747005 CNV Deletion 23290073
esv2747006 CNV Deletion 23290073
dgv1542n71 CNV Loss 21882294
dgv1543n71 CNV Loss 21882294
nsv826569 CNV Gain 20364138
dgv239e201 CNV Deletion 23290073
esv2747009 CNV Deletion 23290073
esv2747010 CNV Deletion 23290073
esv1661784 CNV Insertion 17803354
esv1562329 CNV Insertion 17803354
esv2747012 CNV Deletion 23290073
esv2668583 CNV Deletion 23128226
esv2747013 CNV Deletion 23290073
esv2747014 CNV Deletion 23290073
esv2747015 CNV Deletion 23290073
esv2040735 CNV Deletion 18987734
nsv53631 CNV Loss 16902084
esv2663688 CNV Deletion 23128226
esv1040121 CNV Deletion 17803354
esv2747016 CNV Deletion 23290073
esv2747017 CNV Deletion 23290073
esv2747019 CNV Deletion 23290073
nsv455809 CNV Loss 19166990
nsv899826 CNV Loss 21882294

Relevant External Links for FBRSL1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FBRSL1 Gene

Disorders for FBRSL1 Gene

No disorders were found for FBRSL1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for FBRSL1 Gene

Publications for FBRSL1 Gene

  1. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10997877) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PMID: 19851445) Barcellos L.F. … Criswell L.A. (PLoS Genet. 2009) 3
  4. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  5. PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes. (PMID: 22325352) Gao Z. … Reinberg D. (Mol. Cell 2012) 3

Products for FBRSL1 Gene

Sources for FBRSL1 Gene

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