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FBRS Gene

protein-coding   GIFtS: 46
GCID: GC16P030670

Fibrosin

(Previous name: fibrosin 1)
(Previous symbol: FBS1)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
fibrosin1 2     Fibrogenic Lymphokine2
FBS11 2 3     Probable Fibrosin-12
Fibrosin 11 2     Probable Fibrosin-1 Long Transcript Protein2
FBS2 3     

External Ids:    HGNC: 204421   Entrez Gene: 643192   Ensembl: ENSG000001568607   OMIM: 6086015   UniProtKB: Q9HAH73   

Export aliases for FBRS gene to outside databases

Previous GC identifers: GC16P030579 GC16P028238


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for FBRS Gene:
Fibrosin is a lymphokine secreted by activated lymphocytes that induces fibroblast proliferation (Prakash and
Robbins, 1998 (PubMed 9809749)).(supplied by OMIM, Mar 2008)

GeneCards Summary for FBRS Gene:
FBRS (fibrosin) is a protein-coding gene. An important paralog of this gene is AUTS2.

Gene Wiki entry for FBRS Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000016.9  NC_018927.2  NT_187260.1  
Regulatory elements:
   Regulatory transcription factor binding sites in the FBRS gene promoter:
         E2F-3a   E2F-4   E2F-5   Pax-5   E2F-2   PPAR-alpha   E2F   E2F-1   Pax-4a   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for FBRS

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FBRS


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p11.2   Ensembl cytogenetic band:  16p11.2   HGNC cytogenetic band: 16p11.2

FBRS Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FBRS gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P030670:  view genomic region     (about GC identifiers)

Start:
30,669,752 bp from pter      End:
30,682,135 bp from pter
Size:
12,384 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: FBRS_HUMAN, Q9HAH7 (See protein sequence)
Recommended Name: Probable fibrosin-1  
Size: 460 amino acids; 48388 Da
Caution: Prakash et al. cloned a cDNA corresponding to the 3'UTR of the last exon of the gene (PubMed:9809749).
They have shown that a synthetic peptide derived from this sequence could stimulate fibroblasts growth in vitro,
and that this protein could be a fibrogenic lymphokine, that could stimulate several biological activities
related to scarring. It would be expressed in placenta, skeletal muscle, pancreas, thymus, testis, and
leukocytes. However, it was not confirmed by in vivo data
Sequence caution: Sequence=BAB13872.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAB14094.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: B4DP86 Q96CI9 Q9H9X4
Alternative splicing: 2 isoforms:  Q9HAH7-2   Q9HAH7-1   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FBRS: NX_Q9HAH7

Explore proteomics data for FBRS at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys8, Lys68
  • Modification sites at PhosphoSitePlus

  • See FBRS Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001098549.1  
    ENSEMBL proteins: 
     ENSP00000348489   ENSP00000456204   ENSP00000287468   ENSP00000378511   ENSP00000454920  

    FBRS Human Recombinant Protein Products:

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    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for FBRS 

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    FBRS Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Search eBioscience for ELISAs for FBRS 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR023246 AUTS2

    Graphical View of Domain Structure for InterPro Entry Q9HAH7

    ProtoNet protein and cluster: Q9HAH7


    Find genes that share domains with FBRS           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008083growth factor activity ----
         
    Find genes that share ontologies with FBRS           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for FBRS:
     Elongated cells with protrusio 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FBRS
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FBRS

    miRNA
    Products:
        
    miRTarBase miRNAs that target FBRS:
    hsa-mir-671-5p (MIRT039273), hsa-mir-877-3p (MIRT037203), hsa-mir-484 (MIRT041717)

    Block miRNA regulation of human, mouse, rat FBRS using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FBRS (see all 49):
    hsa-miR-3607-3p hsa-miR-330-5p hsa-miR-200a hsa-miR-29a hsa-miR-486-3p hsa-miR-650 hsa-miR-141 hsa-miR-890
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat FBRS

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: FBRS (NM_001142641)
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    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FBRS

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FBRS


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    endoplasmic reticulum1
    extracellular1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space ----

    Find genes that share ontologies with FBRS           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FBRS
    Interactions:

        Search GeneGlobe Interaction Network for FBRS

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for FBRS (ENSP000002874684) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PCGF3ENSP000003547244STRING: ENSP00000354724
    PCGF5ENSP000003375004STRING: ENSP00000337500
    RNF2ENSP000003564804STRING: ENSP00000356480
    RYBPENSP000004194944STRING: ENSP00000419494
    YAF2ENSP000003280044STRING: ENSP00000328004
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0048146positive regulation of fibroblast proliferation ----

    Find genes that share ontologies with FBRS           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FBRS



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for FBRS gene (2 alternative transcripts): 
    NM_022452.1  NM_001105079.1  

    Unigene Cluster for FBRS:

    Fibrosin
    Hs.247186  [show with all ESTs]
    Unigene Representative Sequence: AK096322
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000356166 ENST00000498588 ENST00000543786 ENST00000484152 ENST00000482749
    ENST00000468966 ENST00000570170 ENST00000494101 ENST00000287468(uc002dzd.4)
    ENST00000395073 ENST00000568722(uc002dzc.4)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat FBRS using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FBRS (see all 49):
    hsa-miR-3607-3p hsa-miR-330-5p hsa-miR-200a hsa-miR-29a hsa-miR-486-3p hsa-miR-650 hsa-miR-141 hsa-miR-890
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat FBRS
    Clone
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    OriGene ORF clones in mouse, rat for FBRS
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FBRS (NM_001142641)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FBRS
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FBRS
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for FBRS
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FBRS
      QuantiTect SYBR Green Assays in human, mouse, rat FBRS
      QuantiFast Probe-based Assays in human, mouse, rat FBRS

    Additional mRNA sequence: 

    AK021680.1 AK022551.1 AK093045.1 AK096322.1 AK298229.1 HQ013238.1 

    8 DOTS entries:

    DT.447958  DT.100031108  DT.100785441  DT.70100132  DT.95297532  DT.95173463  DT.95272123  DT.97824578 

    Selected AceView cDNA sequences (see all 227):

    BQ022226 BU196342 BM922623 CD514951 BE223064 BM981805 BM676664 AW182673 
    BQ276414 AI954123 AW248480 BQ690494 AK021680 BQ641673 BM713462 BF434121 
    BU145914 BU192997 AW189458 BQ675714 BQ888164 CF125915 BI062201 BI522865 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for FBRS (see all 6)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16a · 16b ^ 17
    SP1:                                                                                            -                           
    SP2:        -                       -     -     -     -     -     -     -                       -                           
    SP3:                                                                                            -                           
    SP4:                                                                                                                        
    SP5:                                                                                                                        


    ECgene alternative splicing isoforms for FBRS

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FBRS expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACTTGCGAAT
    FBRS Expression
    About this image


    FBRS expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Testis (Reproductive System)
    FBRS Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FBRS Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.247186
        Custom PCR Arrays for FBRS
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FBRS

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for FBRS gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fbrs1 , 5 fibrosin1, 5 90.51(n)1
    95(a)1
      7 (69.55 cM)5
    141231  NM_010183.11  NP_034313.11 
     1274852215 
    lizard
    (Anolis carolinensis)
    Reptilia FBRS6
    fibrosin
    40(a)
    1 ↔ 1
    GL343516.1(159998-178550)
    zebrafish
    (Danio rerio)
    Actinopterygii fbrs6
    fibrosin
    22(a)
    1 ↔ 1
    12(28605791-28632372) ENSDARG00000074688


    ENSEMBL Gene Tree for FBRS (if available)
    TreeFam Gene Tree for FBRS (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FBRS gene
    AUTS22  FBRSL12  

    Find genes that share paralogs with FBRS           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FBRS (see all 202)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs619972351,2
    C,F--30673889(+) GGGCCC/ACCACG 1 -- us2k12Minor allele frequency- A:0.01NS EU 275
    rs1813485301,2
    --30673897(+) ACGGCA/GCCTTC 1 -- us2k10--------
    rs1451544301,2
    --30674016(+) AGGAA-/CCCACC 1 -- us2k10--------
    rs1475108311,2
    --30674021(+) ACCACC/TGCCTC 1 -- us2k10--------
    rs760829131,2
    F--30674065(+) CACCCC/TTGCCG 1 -- us2k11Minor allele frequency- T:0.03WA 118
    rs1844065611,2
    --30674083(+) CCAGTC/GTGCCA 1 -- us2k10--------
    rs8690741,2
    C,H--30674235(+) GGTGGC/TGGGGA 1 -- us2k19Minor allele frequency- T:0.00NA EA MN NS 780
    rs1400531751,2
    C--30674254(+) GGTACC/TTGTGG 1 -- us2k10--------
    rs1892098571,2
    --30674323(+) GATGAC/TTGCAG 1 -- us2k10--------
    rs8690751,2
    C,H--30674382(+) TGCTGT/GTTCCC 1 -- us2k18Minor allele frequency- G:0.00NA EA MN NS 582

    HapMap Linkage Disequilibrium report for FBRS (30669752 - 30682135 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for FBRS:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv905729CNV Loss21882294
    nsv469724CNV Loss16826518
    nsv905728CNV Loss21882294
    dgv2669n71CNV Loss21882294
    nsv905727CNV Loss21882294
    nsv833188CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FBRS
    DNA2.0 Custom Variant and Variant Library Synthesis for FBRS

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608601    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for FBRS:
    Schistosomiasis

    Find genes that share disorders with FBRS           About GenesLikeMe


    Export disorders for FBRS gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FBRS gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with FBRS)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and analysis of the cDNA for human fibrosin, a novel fibrogenic lymphokine. (PubMed id 9809749)1, 2, 3 Prakash S. and Robbins P.W. (DNA Cell Biol. 1998)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Cloning and analysis of murine cDNA that encodes a fibrogenic lymphokine, fibrosin. (PubMed id 7892239)1, 3 Prakash S....Wyler D.J. (Proc. Natl. Acad. Sci. U.S.A. 1995)
    4. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    5. PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes. (PubMed id 22325352)1 Gao Z....Reinberg D. (Mol. Cell 2012)
    6. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    7. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    8. Fibrosin, a novel fibrogenic cytokine, modulates expression of myofibroblasts. (PubMed id 17083929)1 Prakash S....Robbins P.W. (Exp. Mol. Pathol. 2007)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    10. The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)2 Martin J.... Pennacchio L.A. (Nature 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 64319 HGNC: 20442 AceView: FBS1 Ensembl:ENSG00000156860 euGenes: HUgn64319
    ECgene: FBRS H-InvDB: FBRS

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for FBRS Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FBRS gene:
    Search GeneIP for patents involving FBRS

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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