FBN3 Gene
protein-coding GIFtS: 56
GCID: GC19M008130
|
|
fibrillin 3
| |
Aliases
for FBN3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Fibrillin 31 2 | | Fibrillin-31 | | KIAA17763 |
Export aliases for FBN3 gene to outside databasesPrevious GC identifers: GC00U991241 GC19M008235 GC19M008025 GC19M008036 GC19M007802 |
Summaries
for FBN3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for FBN3:
This gene encodes a protein that belongs to the fibrillin gene family. Fibrillins are extracellular matrix moleculesthat assemble into microfibrils in many connective tissues. This gene is most highly expressed in fetal tissues andits protein product is localized to extracellular microfibrils of developing skeletal elements, skin, lung, kidney,and skeletal muscle. This gene is potentially involved in Weill-Marchesani syndrome. While several transcript variantsmay exist for this gene, their full-length natures have not been described to date. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: FBN3_HUMAN, Q75N90Function: Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occureither in association with elastin or in elastin-free bundles. Fibrillin-containing microfibrils provide long-termforce bearing structural support
|
Genomic Views
for FBN3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_077812.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FBN3 gene promoter:
NF-1 NF-AT NF-AT4 NF-AT2 NF-AT3 SEF-1 (1) Pax-4a NF-AT1
Other transcription factors
Search SABiosciences Chromatin IP Primers for FBN3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FBN3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13 Ensembl cytogenetic band: 19p13.2 HGNC cytogenetic band: 19p13FBN3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M008130: view genomic region
(about GC identifiers)
Start:
|
8,130,287 bp from pter |
End:
|
8,212,650 bp from pter |
Size:
|
82,364 bases |
Orientation:
|
minus strand |
|
Proteins
for FBN3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: FBN3_HUMAN, Q75N90 (See
protein sequence)Recommended Name: Fibrillin-3 precursor Size: 2809 amino acids; 300356 Da
Subcellular location: Secreted, extracellular space, extracellular matrix
Sequence caution: Sequence=BAB47408.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: Q75N91 Q75N92 Q75N93 Q86SJ5 Q96JP8Explore the universe of human proteins at neXtProt for FBN3: NX_Q75N90
Post-translational modifications:
Probably forms intermolecular disulfide bonds either with other FBN3 molecules or with other components of themicrofibrils (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q75N90
FBN3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_115823.3
ENSEMBL proteins: ENSP00000270509 Reactome Protein details: Q75N90
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005578 | proteinaceous extracellular matrix |
IEA | -- |
FBN3 for ontologies About GeneDecksing
FBN3 Antibody Products:
Assay Products for FBN3: |
Protein
Domains /
Families
for FBN3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FBN3 for domains About GeneDecksing
5/8 InterPro domains/families (see all 8):Graphical View of Domain Structure for InterPro Entry Q75N90ProtoNet protein and cluster: Q75N90 2 Blocks protein families: IPB001881 EGF-like calcium-binding IPB006210 Type I EGF
UniProtKB/Swiss-Prot: FBN3_HUMAN, Q75N90Similarity: Belongs to the fibrillin familySimilarity: Contains 44 EGF-like domainsSimilarity: Contains 9 TB (TGF-beta binding) domains |
Function
for FBN3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: FBN3_HUMAN, Q75N90Function: Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occureither in association with elastin or in elastin-free bundles. Fibrillin-containing microfibrils provide long-termforce bearing structural support
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FBN3
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FBN3
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FBN3 (NM_032447) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FBN3 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FBN3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FBN3 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005201 | extracellular matrix structural constituent |
IEA | -- | | GO:0005509 | calcium ion binding |
IEA | -- |
FBN3 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for FBN3:
|
Pathways & Interactions
for FBN3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Integrin Pathway | | | 2 | Rho Family GTPases | | | 3 | Tropoelastin associates with microfibrils | | | 4 | Elastic fibre formation | | | 5 | PTEN Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/13 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for FBN3 (see all 13)
5/6 
Reactome Pathways for FBN3 (see all 6)
FBN3 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FBN3
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
5/23 Interacting proteins for FBN3 (Q75N902, 3 ENSP000002705094) via UniProtKB, MINT, STRING, and/or I2D (see all 23)About this table
|
Drugs & Compounds
for FBN3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FBN3
1 HMDB Compound for FBN3 About this table
Search CenterWatch for drugs/clinical trials and news about FBN3
|
Transcripts
for FBN3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FBN3 gene: NM_032447.3 Unigene Cluster for FBN3: Fibrillin 3 Hs.370362 [show with all ESTs]Unigene Representative Sequence: AY1658631 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000270509(uc002mje.3 uc002mjf.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FBN3
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FBN3
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FBN3 (NM_032447) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FBN3 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FBN3 |
Additional cDNA sequence: AB053450.2 AK074501.1 AK095563.1 AK096539.1 AK131282.1 AY165863.1 AY165864.1 AY165865.1 BC153882.1 7 DOTS entries: DT.100744014 DT.100019307 DT.121439819 DT.97803365 DT.70104387 DT.121439821 DT.427725 24/90 AceView cDNA sequences (see all 90): CD634018 CD634019 CD634025 NM_032447 AY165865 CD634011 CD634036 CD634038 CD634034 AI341180 AY165864 AY165863 CD634024 CD634027 CD634015 CD634007 CD634009 CD633985 CD634014 CD634039 CD634016 AA601715 CD634004 CD634020
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for FBN3 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25 | ^ |
|---|
|
| SP1: | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 26 | ^ | 27 | ^ | 28 | ^ | 29 | ^ | 30 | ^ | 31 | ^ | 32 | ^ | 33 | ^ | 34 | ^ | 35 | ^ | 36 | ^ | 37 | ^ | 38 | ^ | 39 | ^ | 40 | ^ | 41 | ^ | 42 | ^ | 43 | ^ | 44 | ^ | 45 | ^ | 46 | ^ | 47 | ^ | 48 | ^ | 49 | ^ | 50 | ^ | 51a | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | |
| ExUns: | 51b | ^ | 52 | ^ | 53 | ^ | 54 | ^ | 55 | ^ | 56 | ^ | 57 | ^ | 58 | ^ | 59 | ^ | 60 | ^ | 61 | ^ | 62 | ^ | 63 | ^ | 64 | ^ | 65 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | |
ECgene alternative splicing isoforms for FBN3
|
Expression
for FBN3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FBN3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCAATGGGCA
About this image
See FBN3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FBN3
SOURCE GeneReport for Unigene cluster: Hs.370362
UniProtKB/Swiss-Prot: FBN3_HUMAN, Q75N90Tissue specificity: Predominantly expressed in connective tissues such as skeletal muscle, tendon, skin, perichondriumand periosteum. Highly expressed in fetal lung, brain, kidney. Expressed at low level in prostate, testis, mammarygland, uterus, ovary, placenta, bladder, adrenal gland, thyroid, fetal thymus, fetal liver, liver, fetal heart andheart
SABiosciences Custom PCR Arrays for FBN3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FBN3
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FBN3 |
Orthologs
for FBN3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for FBN3 gene from 4/15 species (see all 15) About this table
ENSEMBL Gene Tree for FBN3 (if available)
TreeFam Gene Tree for FBN3 (if available) |
Paralogs
for FBN3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FBN3 gene
- FBN12 LTBP32 SCUBE32 FBLN52 FBN22 LTBP42 EFEMP12 EFEMP22
- SCUBE12 LTBP22 LTBP12 FBLN22 FBLN12 SCUBE22
14 SIMAP similar genes for FBN3 using alignment to 5 protein entries: FBN3_HUMAN (see all proteins):PP187 FBN2 FBN1 PROS1 LTBP1 LTBP2
FBLN2 FBLN1 LTBP3 NELL2 EFEMP1 HMCN1
DKFZp586A1519 EMR2
FBN3 for paralogs About GeneDecksing
|
Genomic Variants
for FBN3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FBN3 (8130287 - 8212650 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for FBN3
2 CNVs: 2238 5078
Human Gene Mutation Database (HGMD): FBN3
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FBN3 |
|
Disorders
/ Diseases
for FBN3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
FBN3 for disorders About GeneDecksing
OMIM gene information: 608529
OMIM disorders: --
6  diseases for FBN3: About MalaCardsweill-marchesani syndrome polycystic ovary syndrome marfan syndrome scoliosis
thyroiditis prostatitis
2 diseases from the University of Copenhagen DISEASES database for FBN3:Polycystic ovary syndrome Weill-Marchesani syndrome Human Genome Epidemiology (HuGE) Navigator: FBN3 (5 documents)
Export disorders for FBN3 gene to outside databases
|
Publications
for FBN3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FBN3 gene, integrated from 9 sources (see all 21):
(articles sorted by number of sources associating them with FBN3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Differential expression of fibrillin-3 adds to microfibril variety in human and avian, but not rodent, connective tissues. (PubMed id 14962672)1, 2, 9 Corson G.M.... Sakai L.Y. (2004)
- Three novel mutations of the fibrillin-1 gene and ten single nucleotide polymorphisms of the fibrillin-3 gene in Marfan syndrome patients. (PubMed id 15221638)1, 2, 9 Uyeda T.... Ito E. (2004)
- Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11347906)1, 2 Nagase T.... Ohara O. (2001)
- Genetic and gene expression analyses of the polycysti c ovary syndrome candidate gene fibrillin-3 and other fibrillin family members in human ovaries. (PubMed id 19692420)1, 9 Prodoehl M.J....Rodgers R.J. (2009)
- Identification of a polycystic ovary syndrome susceptibility variant in fibrillin-3 and association with a metabolic phenotype. (PubMed id 17785364)1, 9 Urbanek M....Dunaif A. (2007)
- Family-based analysis of candidate genes for polycyst ic ovary syndrome. (PubMed id 20200332)1, 9 Ewens K.G....Spielman R.S. (2010)
- Association of fibrillin-3 and transcription factor-7- like 2 gene variants with metabolic phenotypes in PCOS. (PubMed id 22301903)1 Yalamanchi S.K....Dunaif A. (2012)
- Linkage of regulators of TGF-I^ activity in the fetal ovary to polycystic ovary syndrome. (PubMed id 21411746)1 Hatzirodos N....Rodgers R.J. (2011)
- A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
- Fibrillin-3 expression in human development. (PubMed id 20970500)1 Sabatier L....Reinhardt D.P. (2011)
|
External Searches for FBN3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FBN3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FBN3 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing FBN3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FBN3 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FBN3 gene:
Search GeneIP for patents involving FBN3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FBN3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FBN3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FBN3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FBN3 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FBN3 | | OriGene 3'-UTR Clone for FBN3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FBN3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FBN3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FBN3 | | OriGene Custom Protein Services for FBN3 | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FBN3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FBN3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FBN3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FBN3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FBN3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FBN3 |
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 | | | FBN3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FBN3 |
|  |  |  | | | | Search ThermoFisher Antibodies for FBN3 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FBN3 |
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