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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FBLIM1 Gene

protein-coding   GIFtS: 54
GCID: GC01P016083

filamin binding LIM protein 1

 Explore 7 diseases affiliated with
FBLIM1 via our new
 Human Malady Compendium 
Biological research products
for FBLIM1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Filamin Binding LIM Protein 11 2     CSX-Associated LIM2
FBLP-11 2 3     Filamin-Binding LIM Protein 12
FBLP12 3 5     Filamin-Binding LIM Protein-12
CAL1 2     Mitogen-Inducible 2 Interacting Protein2
Migfilin3     Migfilin3
Mitogen-Inducible 2-Interacting Protein2 3     MIGFILIN5
MIG2-Interacting Protein2 3     

External Ids:    HGNC: 246861   Entrez Gene: 547512   Ensembl: ENSG000001624587   OMIM: 6077475   UniProtKB: Q8WUP23   

Export aliases for FBLIM1 gene to outside databases

Previous GC identifers: GC01P015829 GC01P015955 GC01P014604


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FBLIM1:
This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple
C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin
cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a
role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and
may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing
results in multiple transcript variants encoding different isoforms. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: FBLI1_HUMAN, Q8WUP2
Function: Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is
implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated
cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling
complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of
integrins and regulates integrin-mediated cell-cell adhesion

Gene Wiki entry for FBLIM1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004610.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FBLIM1 gene promoter:
         Nkx2-5   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFBLIM1 promoter sequence
   Search SABiosciences Chromatin IP Primers for FBLIM1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FBLIM1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.21   Ensembl cytogenetic band:  1p36.21   HGNC cytogenetic band: 1p36.13

FBLIM1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FBLIM1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P016083:  view genomic region     (about GC identifiers)

Start:
16,083,102 bp from pter      End:
16,113,089 bp from pter
Size:
29,988 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: FBLI1_HUMAN, Q8WUP2 (See protein sequence)
Recommended Name: Filamin-binding LIM protein 1  
Size: 373 amino acids; 40670 Da
Subunit: Interacts with NKX2-5 (By similarity). Isoform 1 and isoform 3 interact with PLEKHC1, FLNA, FLNB and FLNC.
Isoform 2 interacts with FLNB
Subcellular location: Cytoplasm, cell cortex. Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Note=Associated
with actin stress fiber at cell-ECM focal adhesion sites. Isoform 1 and isoform 3 are recruited and localized at actin
stress fibers and clustered at cell-EMC adhesion sites through interaction with PLEKHC1. Isoform 2 is localized at
actin stress fibers
2 PDB 3D structures from and Proteopedia for FBLIM1:
2K9U (3D)        2W0P (3D)    
Secondary accessions: B3KNY0 Q5VVE0 Q5VVE1 Q8IX23 Q96T00 Q9UFD6
Alternative splicing: 3 isoforms:  Q8WUP2-1   Q8WUP2-2   Q8WUP2-3   (May be due to exon skipping)

Explore the universe of human proteins at neXtProt for FBLIM1: NX_Q8WUP2

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8WUP2

  • FBLIM1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001019386.1  NP_001019387.1  NP_060026.2  

    ENSEMBL proteins: 
     ENSP00000422862   ENSP00000423471   ENSP00000421885   ENSP00000387595   ENSP00000364926  
     ENSP00000421764   ENSP00000422075   ENSP00000364921   ENSP00000427052   ENSP00000424920  
     ENSP00000402401   ENSP00000416387   ENSP00000364920   ENSP00000383584  
    Reactome Protein details: Q8WUP2
    Human Recombinant Protein Products: 
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    Uscn Proteins for FBLIM1

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001725stress fiber IDA18829455
    GO:0005829cytosol TAS--
    GO:0005925focal adhesion IEA--
    GO:0005938cell cortex IEA--
    GO:0030054cell junction IDA--


    FBLIM1 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    FBLIM1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR001781 Znf_LIM

    Graphical View of Domain Structure for InterPro Entry Q8WUP2

    ProtoNet protein and cluster: Q8WUP2

    1 Blocks protein family: IPB001781 Zn-binding protein

    UniProtKB/Swiss-Prot: FBLI1_HUMAN, Q8WUP2
    Domain: The N-terminal region is intrinsically disordered
    Similarity: Contains 3 LIM zinc-binding domains


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: FBLI1_HUMAN, Q8WUP2
    Function: Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is
    implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated
    cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling
    complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of
    integrins and regulates integrin-mediated cell-cell adhesion

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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008270zinc ion binding IEA--
    GO:0031005filamin binding IDA19074766


    FBLIM1 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for FBLIM1:
     Increased G2M DNA content  Increased gamma-H2AX phosphory 

    Animal Models:
         Mouse knock-outs for FBLIM1: Fblim1tm1.1Chen Fblim1tm1.2Ref
         6 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Fblim1):
     cellular  hematopoietic system  immune system  no phenotypic analysis  normal 
     skeleton 

    FBLIM1 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Cell-cell junction organization
    Cell junction organization0.69
    Cell-Cell communication0.45
    2Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
    Cell-extracellular matrix interactions0.44

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    3        Reactome Pathways for FBLIM1
        Cell-extracellular matrix interactions
    Cell junction organization
    Cell-Cell communication



    FBLIM1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FBLIM1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/8 Interacting proteins for FBLIM1 (Q8WUP23 ENSP000004163874) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FLNBO753693, ENSP000002959564I2D: score=2 STRING: ENSP00000295956
    FERMT2Q96AC13, ENSP000003428584I2D: score=2 STRING: ENSP00000342858
    FLNAP213333, ENSP000003588664I2D: score=2 STRING: ENSP00000358866
    PXNP490233I2D: score=1 
    FLNCENSP000003271454STRING: ENSP00000327145
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008360regulation of cell shape IEA--
    GO:0016337cell-cell adhesion IMP19074766
    GO:0033623regulation of integrin activation IMP19074766
    GO:0034329cell junction assembly TAS--


    FBLIM1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FBLIM1
    Search CenterWatch for drugs/clinical trials and news about FBLIM1 / FBLI1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FBLIM1 gene (3 alternative transcripts): 
    NM_001024215.1  NM_001024216.1  NM_017556.2  

    Unigene Cluster for FBLIM1:

    Filamin binding LIM protein 1
    Hs.530101  [show with all ESTs]
    Unigene Representative Sequence: NM_017556
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000496928 ENST00000508310 ENST00000510393 ENST00000430076 ENST00000375771(uc001axd.1)
    ENST00000510929 ENST00000502638 ENST00000375766(uc001axe.1) ENST00000483633
    ENST00000502739 ENST00000431771 ENST00000441801(uc001axg.1) ENST00000332305
    ENST00000514156 ENST00000509138 ENST00000400773(uc001axh.1 uc001axi.1)


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    Additional cDNA sequence: 

    AF459643.1 AK027444.1 AK055259.1 AK130732.1 AL133035.1 AY180161.1 BC019895.1 

    14 DOTS entries:

    DT.97838125  DT.436153  DT.100839005  DT.101981007  DT.121450044  DT.97848825  DT.121450051  DT.100787720 
    DT.95372266  DT.102831127  DT.102831129  DT.121450060  DT.121450041  DT.91741673 

    24/165 AceView cDNA sequences (see all 165):

    BG747555 BQ082420 BX096040 CB141474 BI334171 BU191604 BM721201 AW243569 
    CR604326 BM822883 AI867436 BQ674645 BU633652 AK055259 BF438298 AW614039 
    AW083637 AI638392 AI972796 AW179068 BM713018 BM837809 BM726731 CB215706 

    GeneLoc Exon Structure

    5/17 Alternative Splicing Database (ASD) splice patterns (SP) for FBLIM1 (see all 17)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b · 7c · 7d · 7e · 7f · 7g ^ 8a · 8b · 8c ^ 9 ^ 10 ^ 11a · 11b ^ 12a ·
    SP1:                                                                                                                                                        -   
    SP2:              -     -           -     -     -     -                                                                                                         
    SP3:              -     -                 -     -     -                                                                                                         
    SP4:              -     -                 -     -     -                                                                                                         
    SP5:              -     -                 -     -     -           -                                                                                             

    ExUns: 12b ^ 13a · 13b
    SP1:                  
    SP2:                  
    SP3:                  
    SP4:                  
    SP5:                  


    ECgene alternative splicing isoforms for FBLIM1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FBLIM1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See FBLIM1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FBLIM1

    SOURCE GeneReport for Unigene cluster: Hs.530101

    UniProtKB/Swiss-Prot: FBLI1_HUMAN, Q8WUP2
    Tissue specificity: Isoform 1 and isoform 3 are expressed in heart, kidney, lung, pancreas, placenta and platelets.
    Isoform 2 is expressed in brain, heart, kidney, lung, pancreas, placenta, skeletal muscle and platelets

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for FBLIM1 gene from 3/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves FBLIM11 filamin binding LIM protein 1 62.36(n)
    52.92(a)
      419458  XM_417617.3  XP_417617.2 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1541761 zgc:154176 55.8(n)
    48.66(a)
      768160  NM_001077303.1  NP_001070771.1 
    worm
    (Caenorhabditis elegans)
    Secernentea zyx-16
    ZYXin family member (zyx-1)
    10(a)
    1 → many
    II(13056744-13071460)


    ENSEMBL Gene Tree for FBLIM1 (if available)
    TreeFam Gene Tree for FBLIM1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FBLIM1 gene
    LPP2  TRIP62  AJUBA2  WTIP2  ZYX2  LIMD12  
    9 SIMAP similar genes for FBLIM1 using alignment to 10 protein entries:     FBLI1_HUMAN (see all proteins):
    LHX8    LHX4    LHx4    CRIP1    ZYX    FHL1
    LMO2    TRIP6    TRIP6i1

    FBLIM1 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for FBLIM1
    PGOHUM00000242661 PGOHUM00000241531


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/502 NCBI SNPs in FBLIM1 are shown (see all 502    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs348438941,2
    C--14620953(+) GTCTC-/AAAAAA 1 -- int11Minor allele frequency- A:0.00NA 2
    rs1396079881,2
    --16083333(+) CCCCAA/CATCAA 1 -- us2k10--------
    rs767947571,2
    C,F,--16083593(+) GTTTTG/CGGGGG 1 -- us2k13Minor allele frequency- C:0.05NA 124
    rs1448133801,2
    --16083594(+) TTTTGC/GGGGGC 1 -- us2k10--------
    rs1458330821,2
    --16083642(+) AGCAGA/GGACTC 1 -- us2k10--------
    rs1870708041,2
    --16083859(+) TTGACC/TGTGAA 1 -- us2k10--------
    rs1485807871,2
    --16083860(+) TGACCA/GTGAAC 1 -- us2k10--------
    rs716317501,2
    C,F,--16083898(+) CTCTTG/CTGGGA 1 -- us2k17Minor allele frequency- C:0.17NA WA EA 366
    rs756448731,2
    C,--16084213(+) AAGCC-/TCAGCC 1 -- us2k10--------
    rs1895196541,2
    --16084265(+) TCAGAC/TCCAGA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for FBLIM1 (16083102 - 16113089 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for FBLIM1
         1 CNV: 53278
    Human Gene Mutation Database (HGMD): FBLIM1

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    FBLIM1 for disorders           About GeneDecksing

    OMIM gene information: 607747    OMIM disorders: --

    7 diseases for FBLIM1:    About MalaCards
    epidermolysis bullosa    kindler syndrome    skin atrophy    lipoma
    leiomyosarcoma    chondrosarcoma    breast cancer

    1 disease from the University of Copenhagen DISEASES database for FBLIM1:
    Skin atrophy

    Export disorders for FBLIM1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FBLIM1 gene, integrated from 9 sources (see all 31):
    (articles sorted by number of sources associating them with FBLIM1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation. (PubMed id 12679033)1, 2, 3, 9 Tu Y.... Wu C. (2003)
    2. A new member of the LIM protein family binds to filamin B and localizes at stress fibers. (PubMed id 12496242)1, 2, 3, 9 Takafuta T....Shapiro S.S. (2003)
    3. Structural Basis of the Migfilin-Filamin Interaction and Competition with Integrin {beta} Tails. (PubMed id 18829455)1, 2, 9 Lad Y....Calderwood D.A. (2008)
    4. Migfilin, a molecular switch in regulation of integrin activation. (PubMed id 19074766)1, 2, 9 Ithychanda S.S....Qin J. (2009)
    5. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. Physical and functional association of migfilin with cell-cell adhesions. (PubMed id 15671069)1, 9 Gkretsi V....Wu C. (2005)
    9. Migfilin interacts with vasodilator-stimulated phosphoprotein (VASP) and regulates VASP localization to cell-matrix adhesions and migration. (PubMed id 16531412)1, 9 Zhang Y....Wu C. (2006)
    10. Migfilin interacts with Src and contributes to cell-m atrix adhesion-mediated survival signaling. (PubMed id 19833732)1, 9 Zhao J....Wu C. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54751 HGNC: 24686 AceView: FBLP-1 Ensembl:ENSG00000162458 euGenes: HUgn54751
    ECgene: FBLIM1 H-InvDB: FBLIM1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FBLIM1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for FBLIM1 gene:
    Search GeneIP for patents involving FBLIM1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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