Aliases for FAXDC2 Gene
Aliases for FAXDC2 Gene
External Ids for FAXDC2 Gene
- HGNC: 1334
- Entrez Gene: 10826
- Ensembl: ENSG00000170271
- UniProtKB: Q96IV6
Previous HGNC Symbols for FAXDC2 Gene
- C5orf4
Previous GeneCards Identifiers for FAXDC2 Gene
- GC05M154198
Summaries for FAXDC2 Gene
GeneCards Summary for FAXDC2 Gene
FAXDC2 (Fatty Acid Hydroxylase Domain Containing 2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and iron ion binding. An important paralog of this gene is MSMO1.
Additional gene information for FAXDC2 Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAXDC2 Gene
Genomics for FAXDC2 Gene
GeneHancer (GH) Regulatory Elements for FAXDC2 Gene
Promoters and enhancers for FAXDC2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around FAXDC2 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for FAXDC2 Gene
Genomic Locations for FAXDC2 Gene
- chr5:154,817,034-154,859,252
- (GRCh38/hg38)
- Size:
- 42,219 bases
- Orientation:
- Minus strand
- chr5:154,198,051-154,238,812
- (GRCh37/hg19)
Genomic View for FAXDC2 Gene
Genes around FAXDC2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 5q33.2 by Ensembl
- 5q33.2 by Entrez Gene
- 5q33.2 by HGNC
FAXDC2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FAXDC2 Gene
Proteins for FAXDC2 Gene
-
Protein details for FAXDC2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96IV6-FXDC2_HUMAN
- Recommended name:
- Fatty acid hydroxylase domain-containing protein 2
- Protein Accession:
- Q96IV6
- B4DIE1
- Q9BSX6
- Q9H8C7
Protein attributes for FAXDC2 Gene
- Size:
- 333 amino acids
- Molecular mass:
- 39002 Da
- Quaternary structure:
- No Data Available
Protein Expression for FAXDC2 Gene
Post-translational modifications for FAXDC2 Gene
No Post-translational modifications
Other Protein References for FAXDC2 Gene
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for FAXDC2
- Novus Biologicals Antibodies for FAXDC2
-
Abcam antibodies for FAXDC2
- Invitrogen Antibodies for FAXDC2
- GeneTex FAXDC2 antibody for FAXDC2
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for FAXDC2
- Origene Custom Protein Services for FAXDC2
- Novus Biologicals proteins for FAXDC2
- Search GeneTex for Proteins for FAXDC2
-
Abcam proteins for FAXDC2
Assay Products
No data available for DME Specific Peptides for FAXDC2 Gene
Domains & Families for FAXDC2 Gene
Gene Families for FAXDC2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for FAXDC2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for FAXDC2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q96IV6- Family:
-
- Belongs to the sterol desaturase family.
Function for FAXDC2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005506 | iron ion binding | IEA | -- |
| GO:0016491 | oxidoreductase activity | IBA | -- |
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for FAXDC2
-
-
ViGene Biosciences lentiviral particle packaged cDNA for FAXDC2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAXDC2 gene
- Search ViGene Biosciences for FAXDC2
CRISPR Products
-
OriGene CRISPR knockouts for FAXDC2
- genomics-online: gRNA clones - Search results for available C5orf4 gene related products
- Applied Biological Materials CRISPR for FAXDC2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAXDC2
- GenScript: Design CRISPR guide RNA sequences for FAXDC2
miRNA for FAXDC2 Gene
- miRTarBase miRNAs that target FAXDC2
miRNA Products
- Search ViGene Biosciences for FAXDC2
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for FAXDC2
- Browse OriGene Inhibitory RNA Products For FAXDC2
- genomics-online: shRNA clones - Search results for available C5orf4 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for FAXDC2 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for FAXDC2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAXDC2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available C5orf4 gene related products
- orf clones - Search results for available C5orf4 gene related products
- Applied Biological Materials Clones for FAXDC2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for FAXDC2
-
ViGene Biosciences adenoviral particle packaged cDNA for FAXDC2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FAXDC2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAXDC2 gene
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAXDC2 Gene
Localization for FAXDC2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for FAXDC2 Gene
- Membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| endoplasmic reticulum | 3 |
| cytosol | 2 |
| plasma membrane | 1 |
| extracellular | 1 |
| mitochondrion | 1 |
| peroxisome | 1 |
| nucleus | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005789 | endoplasmic reticulum membrane | IBA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for FAXDC2 Gene
Pathways & Interactions for FAXDC2 Gene
No Data Available
Interacting Proteins for FAXDC2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006629 | lipid metabolic process | IBA | -- |
| GO:0008610 | lipid biosynthetic process | IEA | -- |
| GO:0055114 | oxidation-reduction process | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for FAXDC2 Gene
Drugs & Compounds for FAXDC2 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| 3-beta-Hydroxy-4-beta-methyl-5-alpha-cholest-7-ene-4-alpha-carboxylate |
|
|
||||
| 4,4-Dimethyl-5a-cholesta-8,24-dien-3-b-ol |
|
7448-02-4 |
|
|||
| 4a-Carboxy-4b-methyl-5a-cholesta-8,24-dien-3b-ol |
|
|
||||
| Hydrogen Ion |
|
|
||||
| NADP |
|
53-59-8 |
|
Transcripts for FAXDC2 Gene
mRNA/cDNA for FAXDC2 Gene
- (6) REFSEQ mRNAs :
- (10) Additional mRNA sequences :
- (172) Selected AceView cDNA sequences:
- (16) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FAXDC2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for FAXDC2
- genomics-online: gRNA clones - Search results for available C5orf4 gene related products
- Applied Biological Materials CRISPR for FAXDC2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAXDC2
- GenScript: Design CRISPR guide RNA sequences for FAXDC2
miRNA Products
- Search ViGene Biosciences for FAXDC2
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for FAXDC2
- Browse OriGene Inhibitory RNA Products For FAXDC2
- genomics-online: shRNA clones - Search results for available C5orf4 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for FAXDC2 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for FAXDC2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAXDC2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available C5orf4 gene related products
- orf clones - Search results for available C5orf4 gene related products
- Applied Biological Materials Clones for FAXDC2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | · | 5d | · | 5e | · | 5f | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c | · | 8d | ^ | 9a | · | 9b | · | 9c | · | 9d | · | 9e | · | 9f | ^ | 10a | · | 10b | · | 10c | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP9: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP13: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP14: |
| ExUns: | 11 | ^ | 12a | · | 12b | · | 12c | ^ | 13 |
|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||
| SP2: | |||||||||
| SP3: | |||||||||
| SP4: | |||||||||
| SP5: | |||||||||
| SP6: | |||||||||
| SP7: | |||||||||
| SP8: | |||||||||
| SP9: | |||||||||
| SP10: | |||||||||
| SP11: | |||||||||
| SP12: | |||||||||
| SP13: | |||||||||
| SP14: | - |
Expression for FAXDC2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Erythroblasts Hematopoietic Bone Marrow
-
Liver (Hepatobiliary System)
-
Ovary (Reproductive System)
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for FAXDC2 Gene
NURSA nuclear receptor signaling pathways regulating expression of FAXDC2 Gene:
FAXDC2SOURCE GeneReport for Unigene cluster for FAXDC2 Gene:
Hs.519694Evidence on tissue expression from TISSUES for FAXDC2 Gene
- Nervous system(4.9)
- Skin(4.2)
- Liver(2)
Primer Products
-
OriGene qPCR primer pairs for FAXDC2
- genomics-online: primer clones - Search results for available C5orf4 gene related products
No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAXDC2 Gene
Orthologs for FAXDC2 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FAXDC2 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | FAXDC2 33 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | FAXDC2 34 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Faxdc2 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | FAXDC2 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | C13H5ORF4 33 |
|
||
| FAXDC2 34 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | FAXDC2 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | LOC100496051 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | faxdc2 33 34 |
|
||
| Dr.8390 33 |
|
||||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP000091 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG1998 33 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | F49E12.9 33 34 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | ERG25 34 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.11249 34 |
|
OneToOne | |
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.7976 33 |
|
- Species where no ortholog for FAXDC2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- cow (Bos Taurus)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for FAXDC2 Gene
Variants for FAXDC2 Gene
| SNP ID | Clin | Chr 05 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000156060 | -- | 154,833,934(-) | C/T | intron_variant | |
| rs1000207924 | -- | 154,842,447(-) | A/C | genic_upstream_transcript_variant, intron_variant | |
| rs1000207946 | -- | 154,833,627(-) | T/G | intron_variant | |
| rs1000235983 | -- | 154,845,140(-) | C/A | genic_upstream_transcript_variant, intron_variant | |
| rs1000288502 | -- | 154,844,829(-) | G/C | genic_upstream_transcript_variant, intron_variant |
Residual Variation Intolerance Score:
91.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.08;
60.91% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for FAXDC2 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAXDC2 Gene
Disorders for FAXDC2 Gene
Additional Disease Information for FAXDC2
No disorders were found for FAXDC2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAXDC2 Gene
Publications for FAXDC2 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
- Transcription mapping of the 5q- syndrome critical region: cloning of two novel genes and sequencing, expression, and mapping of a further six novel cDNAs. (PMID: 10843801) Boultwood J … Wainscoat JS (Genomics 2000) 2 3 58
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen JV … Mann M (Cell 2006) 3 58
- The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J … Rubin EM (Nature 2004) 4 58
Products for FAXDC2 Gene
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- GenScript: Design CRISPR guide RNA sequences for FAXDC2
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- CloneReady with Over 120,000 Genes
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- Cloud-Clone Corp. disease models service
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- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for FAXDC2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for FAXDC2
- VectorBuilder custom plasmid, inducible vectors for FAXDC2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAXDC2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for available FAXDC2 related products ranked by validation data
- antibodies-online: Search results for available FAXDC2 related products ranked by validation data
- antibodies-online: Search results for available FAXDC2 related products ranked by validation data
- GeneTex FAXDC2 antibody for FAXDC2
- Search GeneTex for Proteins for FAXDC2
- ViGene Biosciences adenoviral particle packaged cDNA for FAXDC2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for FAXDC2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for FAXDC2 gene
- Search ViGene Biosciences for FAXDC2
- Horizon Cell Lines for FAXDC2
- genomics-online: cdna clones - Search results for available FAXDC2 gene related products
- orf clones - Search results for available FAXDC2 gene related products
- genomics-online: gRNA clones - Search results for available FAXDC2 gene related products
- genomics-online: primer clones - Search results for available FAXDC2 gene related products
- genomics-online: shRNA clones - Search results for available FAXDC2 gene related products
Sources for FAXDC2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
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