Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
- GeneCards Team
- Our Publications
- Citing GeneCards
- Licensing Agreement
- Weizmann Institute
- LifeMap Sciences Inc
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

FAXDC2 Gene

protein-coding GIFtS: 38
GCID: GC05M154198

Fatty Acid Hydroxylase Domain Containing 2

(Previous name: chromosome 5 open reading frame 4)
(Previous symbol: C5orf4)

Search for FAXDC2
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
Fatty Acid Hydroxylase Domain Containing 2¹ ²
C5orf4¹ ² ³
Chromosome 5 Open Reading Frame 4¹
Fatty Acid Hydroxylase Domain-Containing Protein 2²

External Ids:	HGNC: 1334¹	Entrez Gene: 10826²	Ensembl: ENSG00000170271⁷	UniProtKB: Q96IV6³

Export aliases for FAXDC2 gene to outside databases

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for FAXDC2 Gene:

FAXDC2 (fatty acid hydroxylase domain containing 2) is a protein-coding gene. Among its related super-pathways are cholesterol biosynthesis III (via desmosterol) and Metabolism. An important paralog of this gene is MSMO1.

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000005.9 NT_029289.11 NC_018916.2

Regulatory elements:

Search SABiosciences Regulatory transcription factor binding sites for FAXDC2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: FAXDC2 promoter sequence

Search SABiosciences Chromatin IP Primers for FAXDC2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAXDC2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q31-q32 Ensembl cytogenetic band: 5q33.2 HGNC cytogenetic band: 5q31-q32

FAXDC2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAXDC2 gene location

GeneLoc information about chromosome 5 GeneLoc Exon Structure

GeneLoc location for GC05M154198: view genomic region (about GC identifiers)

Start:	154,198,051 bp from pter	End:	154,238,812 bp from pter
Size:	40,762 bases	Orientation:	minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: FXDC2_HUMAN, Q96IV6 (See protein sequence)

Recommended Name: Fatty acid hydroxylase domain-containing protein 2

Size: 333 amino acids; 39002 Da

Subcellular location: Membrane; Multi-pass membrane protein (Potential)

Secondary accessions: Q9BSX6 Q9H8C7

Explore the universe of human proteins at neXtProt for FAXDC2: NX_Q96IV6

Explore proteomics data for FAXDC2 at MOPED

Post-translational modifications:

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_Q96IV6

FAXDC2 Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins: NP_115761.2

ENSEMBL proteins:

ENSP00000320604 ENSP00000430286 ENSP00000431084 ENSP00000428992 ENSP00000428834

ENSP00000429004 ENSP00000429837 ENSP00000429876 ENSP00000429406 ENSP00000431015

Human Recombinant Protein Products for FAXDC2:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells Browse OriGene Protein Over-expression Lysates OriGene Custom MassSpec OriGene Custom Protein Services for FAXDC2
	GenScript Custom Purified and Recombinant Proteins Services for FAXDC2
	Novus Biologicals FAXDC2 Protein
	Browse Sino Biological Recombinant Proteins Browse Sino Biological Cell Lysates
	Browse ProSpec Recombinant Proteins
	Browse Proteins at Cloud-Clone Corp.

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016021	integral to membrane	IEA	--

FAXDC2 for ontologies About GeneDecksing

FAXDC2 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for FAXDC2
	GenScript Custom Superior Antibodies Services for FAXDC2
	Novus Biologicals FAXDC2 Antibodies
	Search for Antibodies for FAXDC2 at Abcam
	Browse Antibodies at Cloud-Clone Corp.
	Search ThermoFisher Antibodies for FAXDC2
	Search LSBio for Antibodies for FAXDC2

Assay Products for FAXDC2:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Assay Services for FAXDC2
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for FAXDC2
	Browse Enzo Life Sciences for kits & assays
	Browse ELISAs at Cloud-Clone Corp. Browse CLIAs at Cloud-Clone Corp.

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

HGNC Gene Families:

FATHD: Fatty acid hydroxylase domain containing

1 InterPro protein domain:

IPR006694 Fatty_acid_hydroxylase

Graphical View of Domain Structure for InterPro Entry Q96IV6

ProtoNet protein and cluster: Q96IV6

1 Blocks protein domain: IPB006088 Sterol desaturase

UniProtKB/Swiss-Prot: FXDC2_HUMAN, Q96IV6

Similarity: Belongs to the sterol desaturase family

FAXDC2 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005506	iron ion binding	IEA	--
GO:0016491	oxidoreductase activity	IEA	--

FAXDC2 for ontologies About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Custom generated mouse model solutions for FAXDC2

inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for FAXDC2

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FAXDC2

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FAXDC2

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FAXDC2
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate FAXDC2
		SwitchGear 3'UTR luciferase reporter plasmid: FAXDC2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for FAXDC2
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAXDC2

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for FAXDC2
			Sirion Biotech Customized adenovirus for overexpression of FAXDC2

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene clones in human, mouse for FAXDC2 (see all 4) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript Custom all cDNA clones Services for FAXDC2
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAXDC2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAXDC2
		Sirion Biotech Customized lentivirus for stable overexpression of FAXDC2 Customized lentivirus expression plasmids for stable overexpression of FAXDC2

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for FAXDC2
		Search LifeMap BioReagents cell lines for FAXDC2

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAXDC2

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for FAXDC2 About

See pathways by source

SuperPath

Contained pathways About

cholesterol biosynthesis III (via desmosterol)

Steroid biosynthesis

0.48

Metabolism

Metabolic pathways

0.40

Pathways by source See SuperPaths
Show all pathways

2 Kegg Pathways (Kegg details for FAXDC2):

	Steroid biosynthesis
	Metabolic pathways

FAXDC2 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for FAXDC2

STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

3 Interacting proteins for FAXDC2 (ENSP00000320604⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
DHCR24	ENSP00000360316⁴	STRING: ENSP00000360316
NSDHL	ENSP00000359297⁴	STRING: ENSP00000359297
TM7SF2	ENSP00000279263⁴	STRING: ENSP00000279263

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006633	fatty acid biosynthetic process	IEA	--
GO:0055114	oxidation-reduction process	--	--

FAXDC2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for FAXDC2 (FXDC2)

Search CenterWatch for drugs/clinical trials and news about FAXDC2 / FXDC2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for FAXDC2 gene (2 alternative transcripts):

NM_016348.1 NM_032385.3

Unigene Clusters for FAXDC2:

Fatty acid hydroxylase domain containing 2

Hs.519694 [show with all ESTs], Hs.713175 [show with all ESTs]

Unigene Representative Sequences: AK023820, AL359653

16 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000326080(uc003lvs.4 uc011dde.2) ENST00000423554 ENST00000524250

ENST00000517938 ENST00000520581 ENST00000521518 ENST00000524363 ENST00000522825

ENST00000519501 ENST00000519258 ENST00000523997 ENST00000518651 ENST00000520968

ENST00000517448 ENST00000517874 ENST00000520461

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FAXDC2
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate FAXDC2
		SwitchGear 3'UTR luciferase reporter plasmid: FAXDC2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for FAXDC2
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAXDC2

Clone Products:		OriGene clones in human, mouse for FAXDC2 (see all 4) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript Custom all cDNA clones Services for FAXDC2
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAXDC2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAXDC2
		Sirion Biotech Customized lentivirus for stable overexpression of FAXDC2 Customized lentivirus expression plasmids for stable overexpression of FAXDC2

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for FAXDC2
		Search SABiosciences RT² qPCR Primer Assays in human, mouse, rat FAXDC2
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAXDC2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAXDC2

Additional mRNA sequence: AL359653.1

20 DOTS entries:

DT.100779971 DT.95165718 DT.100779972 DT.120820826 DT.95138911 DT.120820765 DT.100779969 DT.95165716

DT.97819181 DT.453689 DT.95165714 DT.120820993 DT.120820877 DT.120821075 DT.120820766 DT.120820978

DT.120820991 DT.91638727 DT.92427926 DT.95190370

24/172 AceView cDNA sequences (see all 172):

AL359653 BG680571 BC007216 BU178515 BC004506 BM462884 BQ007983 AW294169

AI625383 BQ183178 AV647694 AI274526 AL134385 BM989470 AA029815 BQ651583

AI675447 BF968276 BM701982 CR626161 AL546557 AI659352 CA430965 AL359655

GeneLoc Exon Structure

5/14 Alternative Splicing Database (ASD) splice patterns (SP) for FAXDC2 (see all 14) About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5a	·	5b	·	5c	·	5d	·	5e	·	5f	^	6	^	7	^	8a	·	8b	·	8c	·	8d	^	9a	·	9b	·	9c	·	9d	·	9e	·	9f	^	10a	·	10b	·	10c	^
SP1:					-				-		-		-		-		-																		-										-
SP2:					-				-		-		-		-		-																		-
SP3:					-				-		-		-		-		-																-		-
SP4:					-				-		-		-		-		-		-		-		-		-										-										-
SP5:					-				-												-

ExUns:	11	^	12a	·	12b	·	12c	^	13
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for FAXDC2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

FAXDC2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: --

About this image

See FAXDC2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAXDC2

SOURCE GeneReport for Unigene clusters: Hs.519694 Hs.713175

SABiosciences Custom PCR Arrays for FAXDC2

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for FAXDC2
		Search SABiosciences RT² qPCR Primer Assays in human, mouse, rat FAXDC2
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAXDC2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAXDC2

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAXDC2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals and fungi.

Orthologs for FAXDC2 gene from 7/14 species (see all 14) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
rat (Rattus norvegicus)	Mammalia	LOC691221¹	similar to CG1998-PA	81.22(n) 77.4(a)		691221 XM_001077260.2 XP_001077260.2
chicken (Gallus gallus)	Aves	C13H5orf4¹	chromosome 13 open reading frame, human C5orf4	67.37(n) 63.96(a)		416256 XM_414576.3 XP_414576.3
lizard (Anolis carolinensis)	Reptilia	C5ORF4⁶	Uncharacterized protein	43(a)	1 ↔ 1	GL343205.1(752699-764988)
zebrafish (Danio rerio)	Actinopterygii	Dr.8390²	Danio rerio cDNA clone MGC55420 IMAGE2639318, complete more	77.9(n)		BC044395.1
fruit fly (Drosophila melanogaster)	Insecta	CG1998¹	CG1998	55.69(n) 46.58(a)		32300 NM_132659.3 NP_572887.1
worm (Caenorhabditis elegans)	Secernentea	F49E12.9¹	Protein F49E12.9	47.12(n) 39.1(a)		174339 NM_063362.4 NP_495763.1
baker's yeast (Saccharomyces cerevisiae)	Saccharomycetes	ERG25⁶	C-4 methyl sterol oxidase, catalyzes the first of ...	17(a)	1 → many	VII(610564-611493)

ENSEMBL Gene Tree for FAXDC2 (if available)
TreeFam Gene Tree for FAXDC2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for FAXDC2 gene

MSMO1² CH25H²

FAXDC2 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 5 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs114398971^1,2	C,F	--	154197674(+)	`TTCCCC/TGTATA`	1	--	ds500¹		3		WA NA EA	358
rs112703432^1,2	C,F	--	154197716(+)	`ATTTAC/TGTGTT`	1	--	ds500¹		3		NA	124
rs139728830^1,2		--	154197816(+)	`AGTACA/CACCAG`	1	--	ds500¹		0	--	--	--	--
rs149837672^1,2		--	154197877(+)	`GCAGAC/TGGATT`	1	--	ds500¹		0	--	--	--	--
rs112805237^1,2	F	--	154197936(+)	`ATTATC/TGTTAG`	1	--	ds500¹		1		CSA	2
rs370527809^1,2	C	--	154198030(+)	`CCTTC-/AAAAAA`	1	--	ds500¹		0	--	--	--	--
rs189883354^1,2		--	154198063(+)	`AAGACC/TAGTTT`	1	--	ut3¹		0	--	--	--	--
rs141895621^1,2	C	--	154198080(+)	`CATGCG/TTGCTT`	1	--	ut3¹		0	--	--	--	--
rs182479136^1,2		--	154198083(+)	`GCTTGC/TTTTCA`	1	--	ut3¹		0	--	--	--	--
rs76935179^1,2	C	--	154198149(+)	`CAAGGA/GTTTTG`	1	--	ut3¹		2		CSA WA	120

HapMap Linkage Disequilibrium report for FAXDC2 (154198051 - 154238812 bp)

Structural Variations
Database of Genomic Variants (DGV) variations for FAXDC2: --

SABiosciences Cancer Mutation PCR Assays

SeqTarget long-range PCR primers for resequencing FAXDC2

DNA2.0 Custom Variant and Variant Library Synthesis for FAXDC2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for FAXDC2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAXDC2)

Utopia: connect your pdf to the dynamic
world of online information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Transcription mapping of the 5q- syndrome critical region: cloning of two novel genes and sequencing, expression, and mapping of a further six novel cDNAs. (PubMed id 10843801)^{1, 3} Boultwood J.... Wainscoat J.S. (2000)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)¹ Olsen J.V....Mann M. (2006)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 10826	HGNC: 1334	AceView: C5orf4	Ensembl:ENSG00000170271	euGenes: HUgn10826
ECgene: FAXDC2	Kegg: 10826	H-InvDB: FAXDC2

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for FAXDC2	Pharmacogenomics, SNPs, Pathways

Intellectual Property for FAXDC2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for FAXDC2 gene:
Search GeneIP for patents involving FAXDC2

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Protease Activity Assays and Reagents		Browse Recombinant/Natural Proteins
	Browse Stem Cell Products		Browse Tocris Biochemicals & Compounds
	Browse cDNA Clones		Browse Proteome Profiler Antibody Arrays

	Browse OriGene Antibodies		OriGene RNAi products in human, mouse, rat for FAXDC2
	Browse OriGene qPCR primer pairs and template standards		Browse OriGene Protein Over-expression Lysates
	OriGene Custom Mass Spec		OriGene clones in human, mouse for FAXDC2
	OriGene qSTAR qPCR primer pairs in human, mouse for FAXDC2		Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
	Browse OriGene ORF clones		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for FAXDC2		OriGene Custom Protein Services for FAXDC2

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAXDC2
	QIAGEN SeqTarget long-range PCR primers for resequencing FAXDC2
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAXDC2
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAXDC2
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAXDC2
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAXDC2

	GenScript Custom Purified and Recombinant Proteins Services for FAXDC2		GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for FAXDC2
	GenScript Custom Assay Services for FAXDC2		GenScript Custom Superior Antibodies Services for FAXDC2
	GenScript Custom overexpressing Cell Line Services for FAXDC2		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Search Regulatory tfbs for FAXDC2
	Search Chromatin IP Primers for FAXDC2
	Search RT² qPCR Primer Assays in human, mouse, rat FAXDC2
	Search GNC Networks for FAXDC2
	SABiosciences Custom PCR Arrays for FAXDC2

Search Tocris compounds for FAXDC2 (FXDC2)

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological Cell Lysates
	Browse Sino Biological cDNA Clones
	4000+ Proteins
	Search Sino Biological for antibodies, proteins & pathways
	Protein Production Services
	Transfection Reagents
	Protein A/G/L resins
	Isotyping reagents

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	FAXDC2 antibodies
	FAXDC2 proteins

	Search for Antibodies for FAXDC2 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for FAXDC2
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

	Browse Proteins at Cloud-Clone Corp.
	Browse Antibodies at Cloud-Clone Corp.
	Browse ELISAs at Cloud-Clone Corp.
	Browse CLIAs at Cloud-Clone Corp.

Search LifeMap BioReagents cell lines for FAXDC2

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAXDC2

	SwitchGear 3'UTR luciferase reporter plasmids for FAXDC2
	SwitchGear Promoter luciferase reporter plasmids for FAXDC2

Search ThermoFisher Antibodies for FAXDC2

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAXDC2

	inGenious Targeting Laboratory - Custom generated mouse model solutions for FAXDC2
	inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for FAXDC2

Customized:

	lentivirus for stable overexpression of FAXDC2
	lentivirus expression plasmids for stable overexpression of FAXDC2
	adenovirus for overexpression of FAXDC2

Search LSBio for Antibodies for FAXDC2

Customized transgenic rodents for:

	Humanization
	Biomarker expression
	Off-target effect monitoring
	Translational medicine
	Tissue-specific gene expresssion
	Time-controlled gene expresssion

GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

View Random Gene

Category			TGFB1 (GIFtS: 73) transforming growth factor, beta 1
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes FAXDC2 gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4

Advanced Search

Export list of displayed genes

FAXDC2 Gene

Fatty Acid Hydroxylase Domain Containing 2

Aliases
for FAXDC2 gene

Summaries
for FAXDC2 gene

Genomic Views
for FAXDC2 gene

Proteins
for FAXDC2 gene

Protein Domains /
Families
for FAXDC2 gene

Function
for FAXDC2 gene

Pathways & Interactions
for FAXDC2 gene

Drugs & Compounds
for FAXDC2 gene

Transcripts
for FAXDC2 gene

Expression
for FAXDC2 gene

Orthologs
for FAXDC2 gene

Paralogs
for FAXDC2 gene

Genomic Variants
for FAXDC2 gene

Disorders / Diseases
for FAXDC2 gene

Publications
for FAXDC2 gene

External Searches for FAXDC2 gene

Genome Databases showing FAXDC2 gene

Other Databases showing FAXDC2 gene

Specialized Databases showing FAXDC2 gene

Intellectual Property
for FAXDC2 gene

Products
for FAXDC2 gene

View Random Gene

Advanced Search

Export list of displayed genes

FAXDC2 Gene

Fatty Acid Hydroxylase Domain Containing 2

Aliasesfor FAXDC2 gene

Summariesfor FAXDC2 gene

Genomic Viewsfor FAXDC2 gene

Proteinsfor FAXDC2 gene

Protein Domains /Familiesfor FAXDC2 gene

Functionfor FAXDC2 gene

Pathways & Interactionsfor FAXDC2 gene

Drugs & Compoundsfor FAXDC2 gene

Transcriptsfor FAXDC2 gene

Expression for FAXDC2 gene

Orthologsfor FAXDC2 gene

Paralogsfor FAXDC2 gene

Genomic Variantsfor FAXDC2 gene

Disorders / Diseasesfor FAXDC2 gene

Publicationsfor FAXDC2 gene

External Searches for FAXDC2 gene

Genome Databases showing FAXDC2 gene

Other Databases showing FAXDC2 gene

Specialized Databases showing FAXDC2 gene

Intellectual Propertyfor FAXDC2 gene

Productsfor FAXDC2 gene

View Random Gene

Aliases
for FAXDC2 gene

Summaries
for FAXDC2 gene

Genomic Views
for FAXDC2 gene

Proteins
for FAXDC2 gene

Protein Domains /
Families
for FAXDC2 gene

Function
for FAXDC2 gene

Pathways & Interactions
for FAXDC2 gene

Drugs & Compounds
for FAXDC2 gene

Transcripts
for FAXDC2 gene

Expression
for FAXDC2 gene

Orthologs
for FAXDC2 gene

Paralogs
for FAXDC2 gene

Genomic Variants
for FAXDC2 gene

Disorders / Diseases
for FAXDC2 gene

Publications
for FAXDC2 gene

Intellectual Property
for FAXDC2 gene

Products
for FAXDC2 gene