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FAXDC2 Gene

protein-coding GIFtS: 42
GCID: GC05M154198

Fatty Acid Hydroxylase Domain Containing 2

(Previous name: chromosome 5 open reading frame 4)
(Previous symbol: C5orf4)

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disease database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Fatty Acid Hydroxylase Domain Containing 2¹ ²
C5orf4¹ ² ³
Chromosome 5 Open Reading Frame 4¹
Fatty Acid Hydroxylase Domain-Containing Protein 2²

External Ids:	HGNC: 1334¹	Entrez Gene: 10826²	Ensembl: ENSG00000170271⁷	UniProtKB: Q96IV6³

ORGUL members:

Export aliases for FAXDC2 gene to outside databases

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for FAXDC2 Gene:

FAXDC2 (fatty acid hydroxylase domain containing 2) is a protein-coding gene. GO annotations related to this gene include oxidoreductase activity and iron ion binding. An important paralog of this gene is MSMO1.

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence at NCBI GenBank:

NC_000005.9 NT_029289.12 NC_018916.2

Regulatory elements:

Search for regulatory transcription factor binding sites for FAXDC2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: FAXDC2 promoter sequence

Search Chromatin IP Primers for FAXDC2

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAXDC2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q31-q32 Ensembl cytogenetic band: 5q33.2 HGNC cytogenetic band: 5q31-q32

FAXDC2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAXDC2 gene location

GeneLoc information about chromosome 5 GeneLoc Exon Structure

GeneLoc location for GC05M154198: view genomic region (about GC identifiers)

Start:	154,198,051 bp from pter	End:	154,238,812 bp from pter
Size:	40,762 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, antibodies-online, and/or GeneTex,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

UniProtKB/Swiss-Prot: FXDC2_HUMAN, Q96IV6 (See protein sequence)

Recommended Name: Fatty acid hydroxylase domain-containing protein 2

Size: 333 amino acids; 39002 Da

Secondary accessions: Q9BSX6 Q9H8C7

Explore the universe of human proteins at neXtProt for FAXDC2: NX_Q96IV6

Explore proteomics data for FAXDC2 at MOPED

Post-translational modifications:

Modification sites at neXtProt

Modification sites at PhosphoSitePlus

See FAXDC2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_115761.2

ENSEMBL proteins:

ENSP00000320604 ENSP00000430286 ENSP00000431084 ENSP00000428992 ENSP00000428834

ENSP00000429004 ENSP00000429837 ENSP00000429876 ENSP00000429406 ENSP00000431015

FAXDC2 Human Recombinant Protein Products:

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	Novus Biologicals FAXDC2 Protein
	Browse Sino Biological Recombinant Proteins Browse Sino Biological Cell Lysates
	Browse ProSpec Recombinant Proteins
	Browse Proteins at Cloud-Clone Corp.
	Search eBioscience for Proteins for FAXDC2
	Search GeneTex for Proteins for FAXDC2
	antibodies-online proteins for FAXDC2 (2 products)
	antibodies-online peptides for FAXDC2

FAXDC2 Antibody Products:

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	Novus Biologicals FAXDC2 Antibodies
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	antibodies-online antibodies for FAXDC2

FAXDC2 Assay Products:

	Browse Kits and Assays available from EMD Millipore
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	GenScript Custom Assay Services for FAXDC2
	Browse Enzo Life Sciences for kits & assays
	Browse ELISAs at Cloud-Clone Corp. Browse CLIAs at Cloud-Clone Corp.
	Search eBioscience for ELISAs for FAXDC2
	antibodies-online kits for FAXDC2 (2 products)

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GenesLikeMe)
About This Section

HGNC Gene Families:

FATHD: Fatty acid hydroxylase domain containing

1 InterPro protein domain:

IPR006694 Fatty_acid_hydroxylase

Graphical View of Domain Structure for InterPro Entry Q96IV6

ProtoNet protein and cluster: Q96IV6

1 Blocks protein domain: IPB006088 Sterol desaturase

UniProtKB/Swiss-Prot: FXDC2_HUMAN, Q96IV6

Similarity: Belongs to the sterol desaturase family

Find genes that share domains with FAXDC2 About GenesLikeMe

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
About This Section

Gene Ontology (GO): 2 molecular function terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005506	iron ion binding	IEA	--
GO:0016491	oxidoreductase activity	IEA	--

Find genes that share ontologies with FAXDC2 About GenesLikeMe

Animal Models:

genOway: Develop your customized and physiologically relevant rodent model for FAXDC2

miRNA Products:		miRTarBase miRNAs that target FAXDC2: hsa-mir-21-5p (MIRT030819), hsa-mir-124-3p (MIRT022435)

		Block miRNA regulation of human, mouse, rat FAXDC2 using miScript Target Protectors
		Search for qRT-PCR Assays for microRNAs that regulate FAXDC2
		SwitchGear 3'UTR luciferase reporter plasmid: FAXDC2 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for FAXDC2
		Predesigned siRNA for gene silencing in human, mouse, rat FAXDC2

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for FAXDC2

Clone Products:		OriGene clones in human, mouse for FAXDC2 (see all 5) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript Custom all cDNA clones Services for FAXDC2
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAXDC2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAXDC2

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for FAXDC2
		Browse ESI BIO Cell Lines and PureStem Progenitors for FAXDC2

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAXDC2

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
About This Section

Subcellular locations from UniProtKB/Swiss-Prot

FXDC2_HUMAN, Q96IV6: Membrane; Multi-pass membrane protein (Potential)

Gene Ontology (GO): 1 cellular component term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016021	integral component of membrane	IEA	--

Find genes that share ontologies with FAXDC2 About GenesLikeMe

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GenesLikeMe, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
About This Section

SuperPaths for FAXDC2 About

See pathways by source

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by

SuperPath

Contained pathways About

superpathway of cholesterol biosynthesis

Steroid biosynthesis

0.57

Metabolism

Metabolic pathways

0.38

Find genes that share SuperPaths with FAXDC2 About GenesLikeMe

Pathways by source See SuperPaths
Show all pathways

2 Kegg Pathways (Kegg details for FAXDC2):

	Steroid biosynthesis
	Metabolic pathways

Custom Pathway & Disease-focused RT² Profiler PCR Arrays for FAXDC2
Interactions:

Search GeneGlobe Interaction Network for FAXDC2

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins for FAXDC2 (ENSP00000320604⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 46)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
DHCR24	ENSP00000360316⁴	STRING: ENSP00000360316
C14orf1	ENSP00000256319⁴	STRING: ENSP00000256319
FDFT1	ENSP00000220584⁴	STRING: ENSP00000220584
LSS	ENSP00000348762⁴	STRING: ENSP00000348762
SIGMAR1	ENSP00000277010⁴	STRING: ENSP00000277010

About this table

Gene Ontology (GO): 2 biological process terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006633	fatty acid biosynthetic process	IEA	--
GO:0055114	oxidation-reduction process	--	--

Find genes that share ontologies with FAXDC2 About GenesLikeMe

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, Sets of similar genes according to GenesLikeMe)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for FAXDC2 (FXDC2)

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
About This Section

REFSEQ mRNAs for FAXDC2 gene (5 alternative transcripts):

NM_016348.1 NM_032385.3 XM_005268356.1 XM_005268358.1 XM_006714753.1

Unigene Cluster for FAXDC2:

Fatty acid hydroxylase domain containing 2

Hs.519694 [show with all ESTs]

Unigene Representative Sequence: AK023820

16 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000326080(uc003lvs.4 uc011dde.2) ENST00000423554 ENST00000524250

ENST00000517938 ENST00000520581 ENST00000521518 ENST00000524363 ENST00000522825

ENST00000519501 ENST00000519258 ENST00000523997 ENST00000518651 ENST00000520968

ENST00000517448 ENST00000517874 ENST00000520461

miRNA Products:		Block miRNA regulation of human, mouse, rat FAXDC2 using miScript Target Protectors
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		SwitchGear 3'UTR luciferase reporter plasmid: FAXDC2 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for FAXDC2
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Clone Products:		OriGene clones in human, mouse for FAXDC2 (see all 5) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript Custom all cDNA clones Services for FAXDC2
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAXDC2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAXDC2

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for FAXDC2
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Additional mRNA sequence:

AF159165.1 AK023820.1 AK074245.1 AK127944.1 AK295546.1 AK300938.1 AL359655.1 BC004506.2

BC007216.1

20 DOTS entries:

DT.100779971 DT.95165718 DT.100779972 DT.120820826 DT.95138911 DT.120820765 DT.100779969 DT.97819181

DT.453689 DT.95165716 DT.95165714 DT.120820993 DT.120820877 DT.120821075 DT.120820766 DT.120820978

DT.120820991 DT.91638727 DT.92427926 DT.95190370

Selected AceView cDNA sequences (see all 172):

BQ924287 AI274526 BG680571 BQ007983 AL359653 AW294169 BC004506 BF968276

BU178515 AV647694 BM989470 BQ651583 CR626161 AI275844 AI675447 AI985127

AL359655 AA029815 BC007216 AL134385 BX282700 BM701982 BQ183178 BM462884

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for FAXDC2 (see all 14) About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5a	·	5b	·	5c	·	5d	·	5e	·	5f	^	6	^	7	^	8a	·	8b	·	8c	·	8d	^	9a	·	9b	·	9c	·	9d	·	9e	·	9f	^	10a	·	10b	·	10c	^
SP1:					-				-		-		-		-		-																		-										-
SP2:					-				-		-		-		-		-																		-
SP3:					-				-		-		-		-		-																-		-
SP4:					-				-		-		-		-		-		-		-		-		-										-										-
SP5:					-				-												-

ExUns:	11	^	12a	·	12b	·	12c	^	13
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for FAXDC2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GenesLikeMe, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

FAXDC2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: --

About this image

FAXDC2 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database
selected tissues (see all 3) fully expand


Blood (Hematopoietic System)
Erythroblasts Hematopoietic Bone Marrow

Ovary (Reproductive System)

Liver (Hepatobiliary System)

FAXDC2 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

FAXDC2 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.519694

Custom PCR Arrays for FAXDC2

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		QuantiFast Probe-based Assays in human, mouse, rat FAXDC2

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAXDC2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals and fungi.

Orthologs for FAXDC2 gene from Selected species (see all 15) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
rat (Rattus norvegicus)	Mammalia	Faxdc2¹	fatty acid hydroxylase domain containing 2	81.22(n) 77.4(a)		691221 XM_001077260.3 XP_001077260.3
chicken (Gallus gallus)	Aves	C13H5ORF4¹	chromosome 13 open reading frame, human C5orf4	67.37(n) 63.96(a)		416256 XM_414576.4 XP_414576.3
lizard (Anolis carolinensis)	Reptilia	FAXDC2⁶	fatty acid hydroxylase domain containing 2	44(a)	1 ↔ 1	GL343205.1(752699-764988)
tropical clawed frog (Xenopus tropicalis)	Amphibia	LOC100496051¹	fatty acid hydroxylase domain-containing protein 2-like	68.68(n) 66.77(a)		100496051 XM_002932315.2 XP_002932361.1
zebrafish (Danio rerio)	Actinopterygii	Dr.8390²	Danio rerio cDNA clone MGC55420 IMAGE2639318, complete more	77.9(n)		BC044395.1
fruit fly (Drosophila melanogaster)	Insecta	CG1998¹	CG1998	55.69(n) 46.58(a)		32300 NM_132659.3 NP_572887.1
worm (Caenorhabditis elegans)	Secernentea	F49E12.9¹	F49E12.9	46.94(n) 38.95(a)		174339 NM_063362.5 NP_495763.1
baker's yeast (Saccharomyces cerevisiae)	Saccharomycetes	ERG25⁶	C-4 methyl sterol oxidase, catalyzes the first of ...	20(a)	1 → many	VII(610564-611493) YGR060W

ENSEMBL Gene Tree for FAXDC2 (if available)
TreeFam Gene Tree for FAXDC2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68,Sets of similar genes according to GenesLikeMe)
About This Section

Paralogs for FAXDC2 gene

MSMO1² CH25H²

Find genes that share paralogs with FAXDC2 About GenesLikeMe

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section

SNP ID	Valid	Clinical significance	Chr 5 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs114398971^1,2	C,F	--	154197674(+)	`TTCCCC/TGTATA`	1	--	ds500¹		3		WA NA EA	358
rs112703432^1,2	C,F	--	154197716(+)	`ATTTAC/TGTGTT`	1	--	ds500¹		3		NA	124
rs139728830^1,2		--	154197816(+)	`AGTACA/CACCAG`	1	--	ds500¹		0	--	--	--	--
rs149837672^1,2		--	154197877(+)	`GCAGAC/TGGATT`	1	--	ds500¹		0	--	--	--	--
rs112805237^1,2	F	--	154197936(+)	`ATTATC/TGTTAG`	1	--	ds500¹		1		CSA	2
rs370527809^1,2	C	--	154198030(+)	`CCTTC-/AAAAAA`	1	--	ds500¹		0	--	--	--	--
rs189883354^1,2		--	154198063(+)	`AAGACC/TAGTTT`	1	--	ut3¹		0	--	--	--	--
rs141895621^1,2	C	--	154198080(+)	`CATGCG/TTGCTT`	1	--	ut3¹		0	--	--	--	--
rs182479136^1,2		--	154198083(+)	`GCTTGC/TTTTCA`	1	--	ut3¹		0	--	--	--	--
rs76935179^1,2	C	--	154198149(+)	`CAAGGA/GTTTTG`	1	--	ut3¹		2		CSA WA	120

HapMap Linkage Disequilibrium report for FAXDC2 (154198051 - 154238812 bp)

Structural Variations
Database of Genomic Variants (DGV) variations for FAXDC2: --

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing FAXDC2

DNA2.0 Custom Variant and Variant Library Synthesis for FAXDC2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB, Sets of similar genes according to GenesLikeMe)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for FAXDC2 gene integrated from 10 sources:
(articles sorted by number of sources associating them with FAXDC2)

Utopia: connect your pdf to the dynamic
world of online information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S.... Malek J. (Genome Res. 2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (Nat. Genet. 2004)
Transcription mapping of the 5q- syndrome critical region: cloning of two novel genes and sequencing, expression, and mapping of a further six novel cDNAs. (PubMed id 10843801)^{1, 3} Boultwood J.... Wainscoat J.S. (Genomics 2000)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)¹ Olsen J.V....Mann M. (Cell 2006)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 10826	HGNC: 1334	AceView: C5orf4	Ensembl:ENSG00000170271	euGenes: HUgn10826
ECgene: FAXDC2	Kegg: 10826	H-InvDB: FAXDC2

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for FAXDC2	Pharmacogenomics, SNPs, Pathways

Intellectual Property for FAXDC2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for FAXDC2 gene:
Search GeneIP for patents involving FAXDC2

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, GeneTex, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from genOway)
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	EMD Millipore genomic analysis products

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	Browse OriGene Antibodies		OriGene RNAi products in human, mouse, rat for FAXDC2
	Browse OriGene qPCR primer pairs and template standards		Browse OriGene Protein Over-expression Lysates
	OriGene Custom Mass Spec		OriGene clones in human, mouse for FAXDC2
	OriGene qSTAR qPCR primer pairs in human, mouse for FAXDC2		Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
	Browse OriGene ORF clones		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for FAXDC2		OriGene Custom Protein Services for FAXDC2

	Block miRNA regulation of human, mouse, rat FAXDC2 using miScript Target Protectors		SeqTarget long-range PCR primers for resequencing FAXDC2
	DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAXDC2		Predesigned siRNA for gene silencing in human, mouse, rat FAXDC2
	QuantiFast Probe-based Assays in human, mouse, rat FAXDC2		QuantiTect SYBR Green Assays in human, mouse, rat FAXDC2
	Custom PCR Arrays for FAXDC2		Search Chromatin IP Primers for FAXDC2
	Search Pre-validated RT² qPCR Primer Assays in human, mouse, rat FAXDC2		Search GeneGlobe Interaction Network for FAXDC2
	Search Regulatory tfbs for FAXDC2

	GenScript Custom Purified and Recombinant Proteins Services for FAXDC2		GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for FAXDC2
	GenScript Custom Assay Services for FAXDC2		GenScript Custom overexpressing Cell Line Services for FAXDC2
	CloneReady with Over 120,000 Genes		Gene Synthesis: Any Gene in Any Vector
	Vector-based siRNA and miRNA, Ready for Transfection		Gene Mutant Library, Variants up to 10^11
	Plasmid Preparation		Custom Peptide Services

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Search Tocris compounds for FAXDC2 (FXDC2)

	Browse Sino Biological Proteins
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	Protein Production Services
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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	FAXDC2 antibodies
	FAXDC2 proteins

	Search for Antibodies for FAXDC2 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for FAXDC2
	Custom Antibody / Protein Production Service
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	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

	Browse Proteins at Cloud-Clone Corp.
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	Browse CLIAs at Cloud-Clone Corp.

Browse ESI BIO Cell Lines and PureStem Progenitors for FAXDC2

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAXDC2

	SwitchGear 3'UTR luciferase reporter plasmids for FAXDC2
	SwitchGear Promoter luciferase reporter plasmids for FAXDC2

Search ThermoFisher Antibodies for FAXDC2

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAXDC2

Browse compounds at ApexBio

Search Addgene for plasmids for FAXDC2

	Search eBioscience for proteins for FAXDC2
	Search eBioscience for elisas for FAXDC2
	eBioscience FlowRNA Probe Sets

genOway: Develop your customized and physiologically relevant rodent model for FAXDC2

	antibodies-online antibodies for FAXDC2
	antibodies-online kits for FAXDC2 (2 products)
	antibodies-online peptides for FAXDC2
	antibodies-online proteins for FAXDC2 (2 products)

Search GeneTex for proteins for FAXDC2

GeneCards Home - Full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 2 Nov 2014 , 8 Jan 2015 , 3 Feb 2015

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The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes FAXDC2 gene at Home site.

Version: 3.12.348 25 Feb 2015
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FAXDC2 Gene

Fatty Acid Hydroxylase Domain Containing 2

Aliases
for FAXDC2 gene

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for FAXDC2 gene

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for FAXDC2 gene

Proteins
for FAXDC2 gene

FAXDC2 Human Recombinant Protein Products:

FAXDC2 Antibody Products:

FAXDC2 Assay Products:

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for FAXDC2 gene

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for FAXDC2 gene

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for FAXDC2 gene

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for FAXDC2 gene

Drugs & Compounds
for FAXDC2 gene

Transcripts
for FAXDC2 gene

Expression
for FAXDC2 gene

Orthologs
for FAXDC2 gene

Paralogs
for FAXDC2 gene

Genomic Variants
for FAXDC2 gene

Disorders / Diseases
for FAXDC2 gene

Publications
for FAXDC2 gene

External Searches for FAXDC2 gene

Genome Databases showing FAXDC2 gene

Other Databases showing FAXDC2 gene

Specialized Databases showing FAXDC2 gene

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for FAXDC2 gene

View Random Gene

GeneCards Suite

Advanced Search

Export list of displayed genes

FAXDC2 Gene

Fatty Acid Hydroxylase Domain Containing 2

Aliasesfor FAXDC2 gene

Summariesfor FAXDC2 gene

Genomic Viewsfor FAXDC2 gene

Proteinsfor FAXDC2 gene

FAXDC2 Human Recombinant Protein Products:

FAXDC2 Antibody Products:

FAXDC2 Assay Products:

Domains /Familiesfor FAXDC2 gene

Functionfor FAXDC2 gene

Localizationfor FAXDC2 gene

Pathways & Interactionsfor FAXDC2 gene

Drugs & Compoundsfor FAXDC2 gene

Transcriptsfor FAXDC2 gene

Expression for FAXDC2 gene

Orthologsfor FAXDC2 gene

Paralogsfor FAXDC2 gene

Genomic Variantsfor FAXDC2 gene

Disorders / Diseasesfor FAXDC2 gene

Publicationsfor FAXDC2 gene

External Searches for FAXDC2 gene

Genome Databases showing FAXDC2 gene

Other Databases showing FAXDC2 gene

Specialized Databases showing FAXDC2 gene

Intellectual Propertyfor FAXDC2 gene

Productsfor FAXDC2 gene

View Random Gene

Aliases
for FAXDC2 gene

Summaries
for FAXDC2 gene

Genomic Views
for FAXDC2 gene

Proteins
for FAXDC2 gene

Domains /
Families
for FAXDC2 gene

Function
for FAXDC2 gene

Localization
for FAXDC2 gene

Pathways & Interactions
for FAXDC2 gene

Drugs & Compounds
for FAXDC2 gene

Transcripts
for FAXDC2 gene

Expression
for FAXDC2 gene

Orthologs
for FAXDC2 gene

Paralogs
for FAXDC2 gene

Genomic Variants
for FAXDC2 gene

Disorders / Diseases
for FAXDC2 gene

Publications
for FAXDC2 gene

Intellectual Property
for FAXDC2 gene

Products
for FAXDC2 gene