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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FAU Gene

protein-coding   GIFtS: 60
GCID: GC11M064888

Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously...

(Previous name: Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously...)
 Explore 7 diseases affiliated with
FAU via our new
 Human Malady Compendium 
Biological research products
for FAU
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Finkel-Biskis-Reilly Murine Sarcoma Virus (FBR-MuSV) Ubiquitously
Expressed1 2
     40S Ribosomal Protein S302
Fub11 2     FAU12
Fubi1 2     FAU-Encoded Ubiquitin-Like Protein2
MNSFbeta1 2     FBR-MuSV-Associated Ubiquitously Expressed2
RPS301 2     Monoclonal Nonspecific Suppressor Factor Beta2
S301 2     Ribosomal Protein S302
Asr11     Ubiquitin-Like Protein Fubi And Ribosomal Protein S302
Finkel-Biskis-Reilly Murine Sarcoma Virus (FBR-MuSV) Ubiquitously Expressed
(Fox Derived)1 2
     Ubiquitin-Like-S30 Fusion Protein2
FLJ229861     

External Ids:    HGNC: 35971   Entrez Gene: 21972   Ensembl: ENSG000001498067   OMIM: 1346905   UniProtKB: P628613   
UniProtKB: P355443   

Export aliases for FAU gene to outside databases

Previous GC identifers: GC11M067403 GC11M066569 GC11M065138 GC11M064663 GC11M064644 GC11M061214


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FAU:
This gene is the cellular homolog of the fox sequence in the Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV). It
encodes a fusion protein consisting of the ubiquitin-like protein fubi at the N terminus and ribosomal protein S30 at
the C terminus. It has been proposed that the fusion protein is post-translationally processed to generate free fubi
and free ribosomal protein S30. Fubi is a member of the ubiquitin family, and ribosomal protein S30 belongs to the
S30E family of ribosomal proteins. Whereas the function of fubi is currently unknown, ribosomal protein S30 is a
component of the 40S subunit of the cytoplasmic ribosome. Pseudogenes derived from this gene are present in the
genome. Similar to ribosomal protein S30, ribosomal proteins S27a and L40 are synthesized as fusion proteins with
ubiquitin. (provided by RefSeq, Jul 2008)

Gene Wiki entry for FAU


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.1  NT_167190.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FAU gene promoter:
         GR   AP-1   GR-beta   ATF-2   FOXO4   c-Jun   GR-alpha   ATF6   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFAU promoter sequence
   Search SABiosciences Chromatin IP Primers for FAU

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAU


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13   Ensembl cytogenetic band:  11q13.1   HGNC cytogenetic band: 11q13

FAU Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAU gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M064888:  view genomic region     (about GC identifiers)

Start:
64,888,099 bp from pter      End:
64,889,945 bp from pter
Size:
1,847 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RS30_HUMAN, P62861 (See protein sequence)
Recommended Name: 40S ribosomal protein S30  
Size: 59 amino acids; 6648 Da
Miscellaneous: This ribosomal protein is synthesized as a C-terminal extension protein (CEP) of a ubiquitin-like
protein
Sequence caution: Sequence=AAH33877.1; Type=Erroneous initiation; Sequence=AAQ87877.1; Type=Erroneous initiation;
Sequence=BAB15515.1; Type=Erroneous initiation; Sequence=CAA46714.1; Type=Erroneous initiation; Sequence=CAA46716.1;
Type=Erroneous initiation; Sequence=CAG46772.1; Type=Erroneous initiation;
Secondary accessions: Q05472 Q95261 Q9H5V4

UniProtKB/Swiss-Prot: UBIM_HUMAN, P35544 (See protein sequence)

Recommended Name: Ubiquitin-like protein FUBI  
Size: 74 amino acids; 7760 Da
Miscellaneous: This protein is synthesized with ribosomal S30 as its C-terminal extension
1 PDB 3D structure from and Proteopedia for FAU:
2L7R (3D)    
Secondary accessions: Q9H5V4

Explore the universe of human proteins at neXtProt for FAU: NX_P35544

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P35544

  • FAU Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001988.1  
    ENSEMBL proteins: 
     ENSP00000435370   ENSP00000431822   ENSP00000436110   ENSP00000434440   ENSP00000279259  
     ENSP00000434680   ENSP00000433139   ENSP00000413848  
    Reactome Protein details: P62861
    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    R&D Systems Recombinant & Natural Proteins for FAU (FUBI/MNSF beta)
    Enzo Life Sciences proteins for FAU
    OriGene Purified Protein: FAU
    OriGene Protein Over-expression Lysate: FAU
    OriGene Custom Protein Services for FAU 
    GenScript Custom Purified and Recombinant Proteins Services for FAU
    Novus Biologicals FAU Proteins
    Novus Biologicals FAU Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for FAU

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005829cytosol TAS--
    GO:0005840ribosome ----
    GO:0015935small ribosomal subunit IDA15883184
    GO:0022627cytosolic small ribosomal subunit IDA8706699


    FAU for ontologies           About GeneDecksing



    FAU Antibody Products: 
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    OriGene Antibodies (see all 2): FAU
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    Novus Biologicals FAU Antibodies
    Abcam antibodies for FAU 
    Uscn Antibodies for FAU
    ThermoFisher Antibody for FAU

    Assay Products for FAU: 
    Browse Kits and Assays available from EMD Millipore
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    Uscn ELISAs and CLIAs for FAU


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    FAU for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR006846 Ribosomal_S30
     IPR019954 Ubiquitin_CS
     IPR000626 Ubiquitin
     IPR019955 Ubiquitin_supergroup
     IPR019956 Ubiquitin_subgr

    Graphical View of Domain Structure for InterPro Entry P62861
    Graphical View of Domain Structure for InterPro Entry P35544

    ProtoNet protein and cluster: P62861

    UniProtKB/Swiss-Prot: RS30_HUMAN, P62861
    Similarity: Belongs to the ribosomal protein S30e family

    UniProtKB/Swiss-Prot: UBIM_HUMAN, P35544
    Similarity: Belongs to the ubiquitin family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:
         Genatlas biochemistry entry for FAU:
    Finkel-Biskis-Reilly (FBR)-murine sarcoma virus associated,ubiquitously expressed,viral FOX homolog

    miRNA
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    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAU (see all 7)
    OriGene shRNA RFP: FAU
    OriGene siRNA: FAU
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAU

    Gene Editing
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    Clone
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    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: FAU (NM_001997)
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAU
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAU 

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    Search LifeMap BioReagents cell lines for FAU

    In Situ Assay
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    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for FAU

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0003723RNA binding TAS8395683
    GO:0003735structural constituent of ribosome IDA15883184


    FAU for ontologies           About GeneDecksing


    7 GenomeRNAi human phenotypes for FAU:
     Decreased G3BP1 protein expres  Decreased TP53 protein express  Decreased influenza A H1N1 (A/  Decreased influenza A/WSN/33 r 
     Decreased viability of wild-ty  Increased cell number in G1, s  Nucleolar pre-40S maturation d 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/7 super-pathways (see all 7About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Synthesis of PB1-F2
    8/26 pathways (see all 26)
    Viral Protein Synthesis1.00
    Cytoplasmic Ribosomal Proteins0.86
    Viral mRNA Translation1.00
    CFTR translational fidelity (class I mutations)0.83
    Influenza Viral RNA Transcription and Replication1.00
    SMG6 Cleaves mRNA with Premature Termination Codon0.80
    Synthesis of nascent polypeptide containing signal sequence1.00
    L13a-mediated translational silencing of Ceruloplasmin expression0.79
    2Translation initiation complex formation
    Translation initiation complex formation1.00
    Ribosomal scanning and start codon recognition0.96
    Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S0.98
    Formation of the ternary complex, and subsequently, the 43S complex0.87
    3Metabolism of mRNA
    Metabolism of mRNA1.00
    Metabolism of RNA0.92
    4Disease
    Disease1.00
    5Integrated Breast Cancer Pathway
    Integrated Breast Cancer Pathway1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for FAU
        CFTR translational fidelity (class I mutations)

    2 BioSystems Pathways for FAU 
        Integrated Breast Cancer Pathway
    Cytoplasmic Ribosomal Proteins

    5/32        Reactome Pathways for FAU (see all 32)
        Formation of a pool of free 40S subunits
    Synthesis of PB1-F2
    SMG6 Cleaves mRNA with Premature Termination Codon
    Influenza Life Cycle
    Viral mRNA Translation


    1         Kegg Pathway  (Kegg details for FAU):
        Ribosome


    FAU for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAU

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/172 Interacting proteins for FAU (P355442, 3 ENSP000002792594 P628612, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 172)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RETP079492, ENSP000003479424MINT-60966 MINT-60965 STRING: ENSP00000347942
    COPS6Q7L5N12, ENSP000003041024MINT-63691 STRING: ENSP00000304102
    MAP3K14Q995582MINT-48820
    DDOSTENSP000003641884STRING: ENSP00000364188
    EEF2ENSP000003079404STRING: ENSP00000307940
    About this table

    Gene Ontology (GO): 5/14 biological process terms (GO ID links to tree view) (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0006412translation TAS--
    GO:0006413translational initiation TAS--
    GO:0006414translational elongation TAS--
    GO:0006415translational termination TAS--


    FAU for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    FAU for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FAU
    1 Novoseek chemical compound relationship for FAU gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    arsenite 54.2 1 10069470 (1)

    Search CenterWatch for drugs/clinical trials and news about FAU / UBIM 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FAU gene: 
    NM_001997.4  

    Unigene Cluster for FAU:

    Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
    Hs.387208  [show with all ESTs]
    Unigene Representative Sequence: BM911491
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000529639(uc001ocx.3) ENST00000531743 ENST00000525297 ENST00000527548
    ENST00000531357 ENST00000279259 ENST00000529259 ENST00000526555 ENST00000434372


    miRNA
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    OriGene siRNA: FAU
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    Clone
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    GenScript: all cDNA clones in your preferred vector: FAU (NM_001997)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAU
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAU 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAU
      Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAU

    Additional cDNA sequence: 

    AK026639.1 BC033877.1 CR541974.1 X65923.1 

    24/28 DOTS entries (see all 28):

    DT.97761874  DT.100714868  DT.95316561  DT.101987486  DT.95174284  DT.91687819  DT.100727645  DT.95172595 
    DT.91772688  DT.87005531  DT.95172592  DT.120709024  DT.100714838  DT.100714864  DT.101987963  DT.120709010 
    DT.91772689  DT.97761870  DT.100714859  DT.101987166  DT.120709129  DT.91772658  DT.120709040  DT.120709046 

    24/1565 AceView cDNA sequences (see all 1565):

    BQ213069 BE389674 BU163454 AI342048 AA423805 F29294 BU680020 AI338736 
    CA422984 BQ711914 BU857101 AB058713 BM920312 BU839045 BE276935 BU162001 
    BI712456 CB111315 W68413 BU944775 CD244219 BM687534 BM790242 AA352449 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FAU expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GTTCCCTGGC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See FAU Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FAU

    SOURCE GeneReport for Unigene cluster: Hs.387208
        SABiosciences Custom PCR Arrays for FAU
    Primer
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    In Situ
    Assay Products:
     

     
    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for FAU

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for FAU gene from 8/33 species (see all 33)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fau1 , 5 Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) more1, 5 91.48(n)1
    97.74(a)1
      19 (4.34 cM)5
    141091  NM_001160239.21  NP_001153711.11 
     60578885 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    83(a)
    1 ↔ 1
    GL344606.1(8981-12524)
    African clawed frog
    (Xenopus laevis)
    Amphibia BG552281.12   -- 76.86(n)    BG552281.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc731712 40S ribosomal protein S30 76.89(n)   393710  BC059522.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RpS306
    Ribosomal protein S30
    55(a)
    1 ↔ 1
    3R(16676271-16677156)
    worm
    (Caenorhabditis elegans)
    Secernentea rps-301 Protein RPS-30 58.07(n)
    56.25(a)
      179154  NM_072606.3  NP_505007.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G197506
    AT4G293906
    (see all 3)
    40S ribosomal protein S30
    (see all 3)
    73(a)
    73(a)
    (see all 3)
    many → 1
    many → 1
    (see all 3)
    2(8514954-8516138)
    4(14464987-14465983)
    rice
    (Oryza sativa)
    Liliopsida BE039801.12   -- 78.94(n)    BE039801.1 


    ENSEMBL Gene Tree for FAU (if available)
    TreeFam Gene Tree for FAU (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FAU gene
    ENSG000001737272  
    6 SIMAP similar genes for FAU using alignment to 6 protein entries:     RS30_HUMAN (see all proteins):
    UBC    DKFZp434K0435    UBB    UBBP4    RPS27A    UBD

    FAU for paralogs           About GeneDecksing


    4 Pseudogenes.org Pseudogenes for FAU
    PGOHUM00000249930 PGOHUM00000237883 PGOHUM00000258194 PGOHUM00000241951


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    1 NCBI SNPs in FAU are shown     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs93335821,2
    C,F,H,--64887616(-) TGGCCG/AGACTT 1 -- ds50017Minor allele frequency- A:0.01NS EA CSA WA 696

    HapMap Linkage Disequilibrium report for FAU (64888099 - 64889945 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for FAU: --

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    FAU for disorders           About GeneDecksing

    OMIM gene information: 134690    OMIM disorders: --

    7 diseases for FAU:    About MalaCards
    sarcoma    non-hodgkin lymphoma    multiple endocrine neoplasia    hodgkin's lymphoma
    osteosarcoma    breast cancer    malaria

    3 Novoseek disease relationships for FAU gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    sarcoma 67.9 9 1326960 (1), 8395683 (1), 7642109 (1), 7774934 (1) (see all 8)
    osteosarcoma 40.5 1 12660817 (1)
    tumors 0 6 10069470 (2), 12660817 (1), 7512365 (1), 8406491 (1)


    Export disorders for FAU gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FAU gene, integrated from 9 sources (see all 36):
    (articles sorted by number of sources associating them with FAU)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genomic structure and expression of the human fau gene: encoding the ribosomal protein S30 fused to a ubiquitin-like protein. (PubMed id 1326960)1, 2, 9 Kas K.... Merregaert J. (1992)
    2. fau cDNA encodes a ubiquitin-like-S30 fusion protein and is expressed as an antisense sequence in the Finkel-Biskis-Reilly murine sarcoma virus. (PubMed id 8395683)1, 2, 9 Michiels L....Merregaert J. (1993)
    3. Assignment of the human FAU gene to a subregion of chromosome 11q13. (PubMed id 8406491)1, 3, 9 Kas K....Larsson C. (1993)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Dysregulated expression of Fau and MELK is associated with poor prognosis in breast cancer. (PubMed id 19671159)1, 9 Pickard M.R....Williams G.T. (2009)
    7. fau and its ubiquitin-like domain (FUBI) transforms human osteogenic sarcoma (HOS) cells to anchorage-independence. (PubMed id 12660817)1, 9 Rossman T.G....Komissarova E.V. (2003)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    9. Host cell interactome of HIV-1 Rev includes RNA helica ses involved in multiple facets of virus production. (PubMed id 22174317)1 Naji S....Gerace L. (2012)
    10. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 2197 HGNC: 3597 AceView: FAUandZNHIT2andSYVN1 Ensembl:ENSG00000149806 euGenes: HUgn2197
    ECgene: FAU Kegg: 2197 H-InvDB: FAU

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FAU Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for FAU Genetics and Cytogenetics in Oncology and Haematology
    NIEHS-SNPshttp://egp.gs.washington.edu/data/fau/
    NIEHS-SNPshttp://egp.gs.washington.edu/data/fau/

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for FAU gene:
    Search GeneIP for patents involving FAU

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

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