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FAT1 Gene

protein-coding GIFtS: 56

GC04M187746

FAT tumor suppressor homolog 1 (Drosophila)
(Previous name: FAT tumor suppressor (Drosophila) homolog )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: FAT)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
CDHF7 ^¹, ², ³
FAT ^², ³, ⁵
ME5 ^²
hFat1 ^²

Descriptions
Cadherin-related tumor suppressor homolog ^³
FAT tumor suppressor (Drosophila) homolog ^¹
FAT tumor suppressor 1 ^²
FAT tumor suppressor homolog 1 (Drosophila) ^²
Protein fat homolog ^³
cadherin ME5 ^²
cadherin family member 7 ^²
cadherin-related tumor suppressor ^²

External Ids
HGNC: 3595¹
Entrez Gene: 2195²
UniProtKB: Q14517³
Ensembl: ENSG00000083857⁷

Search outside databases for aliases for FAT1 gene

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for FAT1:

This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for

controlling cell proliferation during Drosophila development. The gene product is a member of the

cadherin superfamily, a group of integral membrane proteins characterized by the presence of

cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product

has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is

expressed at high levels in a number of fetal epithelia. Its product probably functions as an

adhesion molecule and/or signaling receptor, and is likely to be important in developmental

processes and cell communication. Transcript variants derived from alternative splicing and/or

alternative promoter usage exist, but they have not been fully described. [provided by RefSeq]

UniProtKB/Swiss-Prot: FAT1_HUMAN, Q14517

Function: Could function as a cell-adhesion protein

Gene Wiki entry for FAT1 (FAT)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q35 Ensembl cytogenetic band: 4q35.2 HGNC cytogenetic band: 4q35.2

FAT1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 4 GeneLoc Exon Structure

GeneLoc location for GC04M187746: (about GC identifiers)

Start:	187,745,931 bp from pter
End:	187,881,981 bp from pter
Size:	136,051 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000004.10 NT_022792.17

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: FAT1_HUMAN, Q14517 (See protein sequence)

Recommended Name: Protocadherin Fat 1 precursor

Size: 4590 amino acids; 506278 Da

Subcellular location: Cell membrane; Single-pass type I membrane protein (By similarity)

Post-translational modifications:

Phosphorylated upon DNA damage, probably by ATM or ATR¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_005236.2

ENSEMBL proteins:

ENSP00000260147

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
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	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (FAT)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	IEA	--
GO:0005887	integral to plasma membrane	TAS	8586420

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Antibodies for FAT1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for FAT1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (FAT), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for FAT1

Assays for FAT1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry Q14517

ProtoNet protein and cluster: Q14517

5 Blocks protein families:

IPB000152 Aspartic acid and asparagine hydroxylation site

IPB001791 Laminin G

IPB001881 EGF-like calcium-binding

IPB002126 Cadherin

IPB003129 Thrombospondin

UniProtKB/Swiss-Prot: FAT1_HUMAN, Q14517

Similarity: Contains 34 cadherin domains

Similarity: Contains 5 EGF-like domains

Similarity: Contains 1 laminin G-like domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (FAT1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (FAT)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_005245

Applied Biosystems Silencer® siRNAs for FAT1

Sigma-Aldrich siRNA and siRNA Panels for FAT1

Sigma-Aldrich shRNA Panels and shRNA for FAT1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_005245
Myc/DDK tagged cDNA clone in CMV expression vector: NM_005245
untagged cDNA clone in CMV expression vector: NM_005245

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_005245

UniProtKB/Swiss-Prot: FAT1_HUMAN, Q14517

Function: Could function as a cell-adhesion protein

Genatlas biochemistry entry for FAT1:

Drosophila tumor suppressor fat homolog,expressed in many epithelial and some endothelial

cells,putative adhesion molecule,cadherin superfamilily

8 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Fat1):

lethality-postnatal	lethality-prenatal/perinatal	nervous system	pigmentation	renal/urinary system
respiratory system	skin/coat/nails	vision/eye

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005509	calcium ion binding	IEA	--
GO:0005515	protein binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

5/9 Interacting proteins for FAT1 (Q14517² ENSP00000260147³) via UniProtKB, MINT, and/or STRING (see all 9 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
HOMER3	Q9NSC5², ENSP00000348150³	MINT-3370401 MINT-3370454 MINT-3370427 MINT-3370268 STRING (score=.968)
ENAH	Q8N8S7², ENSP00000284563³	MINT-3370478 MINT-3370511 STRING (score=.87)
HOMER1	Q86YM7², ENSP00000334382³	MINT-3370381 STRING (score=.78)
FABP4	ENSP00000256104³	STRING (score=.732)
--	P28738²	MINT-3370187
--	O88448²	MINT-3370206
--	Q99JP6²	MINT-3370150 MINT-3370325
--	Q9Z2Y3²	MINT-3370128
--	O88447²	MINT-3370225

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4 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007155	cell adhesion	TAS	8586420
GO:0007156	homophilic cell adhesion	IEA	--
GO:0007267	cell-cell signaling	TAS	8586420
GO:0009653	anatomical structure morphogenesis	TAS	8586420

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for FAT1

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (FAT1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (FAT)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_005245

Sigma-Aldrich siRNA and siRNA Panels for FAT1

Sigma-Aldrich shRNA Panels and shRNA for FAT1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_005245

REFSEQ mRNAs for FAT1 gene:

NM_005245.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_005245

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_005245
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_005245
                                 untagged cDNA clone in CMV expression vector: NM_005245

Additional cDNA sequence:

AK307938.1 BC012432.1 CR598584.1 D88798.1 EF139845.1 X87241.1

16 DOTS entries:

DT.317047 DT.97801132 DT.75107345 DT.100813734 DT.92444050 DT.102824623 DT.91745710 DT.97786274

DT.100813735 DT.92444046 DT.100018351 DT.100740143 DT.40266667 DT.92444051 DT.121236013 DT.92444045

24/293 AceView cDNA sequences (see all 293 ):

AW294542 BM685014 BM724675 BC012432 AW069476 BU729008 AA769841 BM818370

BX103284 BM698320 BF515335 AI569323 BI494532 AI217914 BM723967 BP428660

BF337432 BQ718467 AI217202 CA489183 AA743948 AI587563 AA639577 AA635705

Unigene Cluster for FAT1:

FAT tumor suppressor homolog 1 (Drosophila)

Hs.481371 [show with all ESTs]

Unigene Representative Sequence: NM_005245

GeneLoc Exon Structure

5/11 Alternative Splicing Database (ASD) splice patterns (SP) for FAT1 (see all 11 )

ExUns:	1	^	2	^	3	^	4a	·	4b	^	5	^	6	^	7	^	8	^	9a	·	9b	^	10	^	11	^	12a	·	12b	^	13	^	14	^	15	^	16	^	17a	·	17b	·	17c	^	18	^	19	^	20a	·	20b	^
SP1:
SP2:
SP3:
SP4:
SP5:

ExUns:	21	^	22a	·	22b	^	23a	·	23b	^	24	^	25	^	26a	·	26b
SP1:
SP2:
SP3:
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for FAT1

1 Ensembl transcript including schematic representation:

ENST00000260147

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

FAT1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for FAT1

¹ / ²

3 probe-sets matching FAT1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
40454_at²	U95-A	1	1.00	1.00	1.00	1.00	--	--	--	--	--
201579_at²	U133-A	1	1.00	1.00	--	--	--	--	--	--	--
201579_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks FAT1 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: ACACAGTTTT

SOURCE GeneReport for Unigene cluster: Hs.481371
UniProtKB/Swiss-Prot: FAT1_HUMAN, Q14517
Tissue specificity: Expressed in many epithelial and some endothelial and smooth muscle cells

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for FAT1 gene from 5/11 species (see all 11 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	FAT1¹	--	FAT tumor suppressor homolog 1 (Drosophila)	86.95(n) 91.17(a)	475621 XM_532835.2 XP_532835.2
cow (Bos taurus)	FAT1¹	--	FAT tumor suppressor homolog 1 (Drosophila)	84.18(n) 89.93(a)	508251 XM_864984.2 XP_870077.1
rat (Rattus norvegicus)	Fat1¹	--	FAT tumor suppressor homolog 1 (Drosophila)	82.93(n) 88.16(a)	83720 NM_031819.1 NP_114007.1
mouse (Mus musculus)	Fat1^{1, 5}	8 (25.00 cM)⁵	FAT tumor suppressor homolog 1 (Drosophila)^{1, 5}	82.51(n)¹ 88.14(a)¹	14107¹ NM_001081286.1¹ NP_001074755.1¹ AA647211⁵ AJ250768⁵ (see all 23)
chicken (Gallus gallus)	FAT¹	--	FAT tumor suppressor homolog 1 (Drosophila)	76.35(n) 81.43(a)	395168 XM_420680.2 XP_420680.2

About this table Species with no ortholog for FAT1

ENSEMBL Gene Tree for FAT1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for FAT1 gene

FAT3² FAT2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/807 NCBI SNPs in FAT1 are shown (see all 807 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 282)

AB	SNP ID	Valid	Chr 4 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs367863^1,2	A,C,F,H	187866134(+)	`CTAAAC/GAAATC`	1	F/L	mis¹		14	MN NA EU EA WA	1210
	rs328418^1,2	A,C,F,H	187794887(-)	`CTATCA/GCGTCA`	1	H/R	mis¹ ese³		12	MN EU EA WA NA	1158
	rs11939575^1,2	A,C,F,H	187864786(+)	`TCTTCC/TGGCGT`	1	R/G	mis¹ ese³		8	EU EA WA	836
	rs3733414^1,2	A,C,F,H	187866764(+)	`GGTGTA/CCTTTT`	1	S/R	mis¹		17	EA NA EU WA	2896
	rs2637777^1,2	C,F,H	187762014(-)	`TCACCG/TCTTCT`	1	S/A	mis¹ ese³		14	EA NA EU WA	2604
	rs3733406^1,2	C,F,H	187776582(+)	`TCCAAT/CAGGCA`	1	V/I	mis¹ ese³		13	EA NA EU WA	2532
	rs3733413^1,2	C,F,H	187866532(+)	`CATGAC/TAGTAG`	1	V/I	mis¹ ese³		15	EU EA WA NA	1511
	rs3796648^1,2	C,F,H	187777912(+)	`ATGTCG/CTCTAC`	1	E/D	mis¹ ese³		9	EU EA WA NA	906
	rs2304867^1,2	C,F,H	187786422(-)	`TCACCG/ACTTCC`	1	T/A	mis¹ ese³		12	EA NA EU WA	2450
	rs1280097^1,2	C,F,H	187756200(+)	`CATGGG/CTTGGA`	1	N/K	mis¹ ese³		6	MN EU EA WA NA	672

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HapMap Linkage Disequilibrium images for FAT1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 600976

2 Novoseek disease relationships for FAT1 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
breast cancer	4.49	3	16581652 (2), 16865240 (1)
tumors	0.00	1	15922730 (1)

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Human Genome Epidemiology Navigator: FAT1 (2 documents)

(Possibly Related Articles in Doctor's Guide)
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DG DISPATCH - EASD: Avandia Positively Impacts On Factors Linked With Insulin Resistance

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/32 PubMed articles for FAT1 gene (see all 32 ):

Molecular cloning and tissue expression of FAT, the human homologue of the Drosophila fat gene that is located on chromosome 4q34-q35 and encodes a putative adhesion molecule. (PubMed id 8586420)^{1, 2, 3, 4} Dunne J.... Owen M.J. (1995)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{3, 4} Olsen J.V....Mann M. (2006)
Differentially spliced isoforms of FAT1 are asymmetrically distributed within migrating cells. (PubMed id 17500054)^{1, 3} Braun G.S....Moeller M.J. (2007)
Processing of the human protocadherin Fat1 and translocation of its cytoplasmic domain to the nucleus. (PubMed id 15922730)^{1, 3} Magg T....Hofer H.W. (2005)
The intracellular domain of the human protocadherin hFat1 interacts with Homer signalling scaffolding proteins. (PubMed id 16979624)^{1, 3} Schreiner D....Hofer H.W. (2006)
Frequent loss of heterozygosity and altered expression of the candidate tumor suppressor gene 'FAT' in human astrocytic tumors. (PubMed id 19126244)³ Chosdol K....Sinha S. (2009)
Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population. (PubMed id 19328558)³ Yosifova A....Nakamura Y. (2009)
Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. (PubMed id 19159218)⁴ Chen R.... Zou H. (2009)
Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)⁴ Cantin G.T....Yates J.R. III (2008)
Genetic variation of the FAT gene at 4q35 is associated with bipolar affective disorder. (PubMed id 17938632)³ Abou Jamra R....Cichon S. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 2195	HGNC: 3595	AceView: FAT	Ensembl:ENSG00000083857	euGenes: HUgn2195
ECgene: FAT1	H-InvDB: FAT1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for FAT1
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for FAT1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for FAT1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for FAT1		Antibodies for FAT1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for FAT1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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Search Novus for antibodies for FAT1

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FAT1 Gene

protein-coding GIFtS: 56

Aliases &
Descriptions
for FAT1

Summaries
for FAT1

Genomic Location
for FAT1

Proteins
for FAT1

Protein Domains/
Families
for FAT1

Gene Function
for FAT1

Pathways & Interactions
for FAT1

Drugs & Compounds
for FAT1

Transcripts
for FAT1

Expression
for FAT1

Orthologs
for FAT1

Paralogs
for FAT1

SNPs/Variants
for FAT1

Disorders & Mutations
for FAT1

Medical News
for FAT1

Publications
for FAT1

Search for FAT1

Genome Databases showing FAT1

Other Databases showing FAT1

Specialized Databases showing FAT1

Licensable Technologies
for FAT1

Services
for FAT1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

FAT1 Gene

protein-coding GIFtS: 56

Aliases & Descriptionsfor FAT1

Summariesfor FAT1

Genomic Locationfor FAT1

Proteinsfor FAT1

Protein Domains/Familiesfor FAT1

Gene Functionfor FAT1

Pathways & Interactionsfor FAT1

Drugs & Compoundsfor FAT1

Transcriptsfor FAT1

Expression for FAT1

Orthologsfor FAT1

Paralogsfor FAT1

SNPs/Variantsfor FAT1

Disorders & Mutationsfor FAT1

Medical Newsfor FAT1

Publicationsfor FAT1

Search for FAT1

Genome Databases showing FAT1

Other Databases showing FAT1

Specialized Databases showing FAT1

Licensable Technologiesfor FAT1

Servicesfor FAT1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for FAT1

Summaries
for FAT1

Genomic Location
for FAT1

Proteins
for FAT1

Protein Domains/
Families
for FAT1

Gene Function
for FAT1

Pathways & Interactions
for FAT1

Drugs & Compounds
for FAT1

Transcripts
for FAT1

Expression
for FAT1

Orthologs
for FAT1

Paralogs
for FAT1

SNPs/Variants
for FAT1

Disorders & Mutations
for FAT1

Medical News
for FAT1

Publications
for FAT1

Licensable Technologies
for FAT1

Services
for FAT1