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Aliases for FASTKD5 Gene

Aliases for FASTKD5 Gene

  • FAST Kinase Domains 5 2 3
  • FAST Kinase Domain-Containing Protein 5 3
  • DJ1187M17.5 3
  • KIAA1792 4

External Ids for FASTKD5 Gene

Summaries for FASTKD5 Gene

GeneCards Summary for FASTKD5 Gene

FASTKD5 (FAST Kinase Domains 5) is a Protein Coding gene. GO annotations related to this gene include protein kinase activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FASTKD5 Gene

Genomics for FASTKD5 Gene

Genomic Location for FASTKD5 Gene

Start:
3,146,519 bp from pter
End:
3,159,897 bp from pter
Size:
13,379 bases
Orientation:
Minus strand

Genomic View for FASTKD5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FASTKD5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FASTKD5 Gene

Regulatory Elements for FASTKD5 Gene

Proteins for FASTKD5 Gene

  • Protein details for FASTKD5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7L8L6-FAKD5_HUMAN
    Recommended name:
    FAST kinase domain-containing protein 5
    Protein Accession:
    Q7L8L6
    Secondary Accessions:
    • Q96JN3
    • Q9H5D1
    • Q9H8Y3

    Protein attributes for FASTKD5 Gene

    Size:
    764 amino acids
    Molecular mass:
    86574 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB15696.1; Type=Frameshift; Positions=662; Evidence={ECO:0000305}; Sequence=BAB47421.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for FASTKD5 Gene

Proteomics data for FASTKD5 Gene at MOPED

Post-translational modifications for FASTKD5 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys87

Other Protein References for FASTKD5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FASTKD5 Gene

Domains for FASTKD5 Gene

Protein Domains for FASTKD5 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

FAKD5_HUMAN
Domain:
  • Contains 1 RAP domain.:
    • Q7L8L6
Family:
  • Belongs to the FAST kinase family.:
    • Q7L8L6
genes like me logo Genes that share domains with FASTKD5: view

No data available for Gene Families for FASTKD5 Gene

Function for FASTKD5 Gene

Gene Ontology (GO) - Molecular Function for FASTKD5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004672 protein kinase activity IEA --
GO:0005515 protein binding IPI 25416956
GO:0044822 poly(A) RNA binding IDA 22681889
genes like me logo Genes that share ontologies with FASTKD5: view
genes like me logo Genes that share phenotypes with FASTKD5: view

miRNA for FASTKD5 Gene

miRTarBase miRNAs that target FASTKD5

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for FASTKD5 Gene

Localization for FASTKD5 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FASTKD5 Gene COMPARTMENTS Subcellular localization image for FASTKD5 gene
Compartment Confidence
mitochondrion 5
cytosol 2
nucleus 1

Gene Ontology (GO) - Cellular Components for FASTKD5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IDA 20869947
genes like me logo Genes that share ontologies with FASTKD5: view

Pathways for FASTKD5 Gene

SuperPathways for FASTKD5 Gene

No Data Available

Gene Ontology (GO) - Biological Process for FASTKD5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006468 protein phosphorylation IEA --
GO:0045333 cellular respiration ISS 20869947
genes like me logo Genes that share ontologies with FASTKD5: view

No data available for Pathways by source for FASTKD5 Gene

Transcripts for FASTKD5 Gene

mRNA/cDNA for FASTKD5 Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(218) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FASTKD5 Gene

FAST kinase domains 5:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FASTKD5 Gene

No ASD Table

Relevant External Links for FASTKD5 Gene

GeneLoc Exon Structure for
FASTKD5
ECgene alternative splicing isoforms for
FASTKD5

Expression for FASTKD5 Gene

mRNA expression in normal human tissues for FASTKD5 Gene

mRNA differential expression in normal tissues according to GTEx for FASTKD5 Gene

This gene is overexpressed in Muscle - Skeletal (4.5).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FASTKD5 Gene

SOURCE GeneReport for Unigene cluster for FASTKD5 Gene Hs.741168

genes like me logo Genes that share expressions with FASTKD5: view

Orthologs for FASTKD5 Gene

This gene was present in the common ancestor of animals.

Orthologs for FASTKD5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FASTKD5 36
  • 99.3 (n)
  • 98.95 (a)
FASTKD5 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FASTKD5 36
  • 86.16 (n)
  • 80.29 (a)
dog
(Canis familiaris)
Mammalia FASTKD5 36
  • 84.28 (n)
  • 76.88 (a)
FASTKD5 37
  • 77 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fastkd5 36
  • 81.03 (n)
  • 74.77 (a)
Fastkd5 16
Fastkd5 37
  • 70 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FASTKD5 37
  • 63 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fastkd5 36
  • 81.78 (n)
  • 75.63 (a)
chicken
(Gallus gallus)
Aves FASTKD5 36
  • 57.7 (n)
  • 47.54 (a)
FASTKD5 37
  • 43 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia fastkd5 36
  • 55.28 (n)
  • 49.66 (a)
zebrafish
(Danio rerio)
Actinopterygii FASTKD5 37
  • 35 (a)
OneToOne
LOC569940 36
  • 51.1 (n)
  • 40.69 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG2124 37
  • 19 (a)
OneToOne
Species with no ortholog for FASTKD5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FASTKD5 Gene

ENSEMBL:
Gene Tree for FASTKD5 (if available)
TreeFam:
Gene Tree for FASTKD5 (if available)

Paralogs for FASTKD5 Gene

No data available for Paralogs for FASTKD5 Gene

Variants for FASTKD5 Gene

Sequence variations from dbSNP and Humsavar for FASTKD5 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
VAR_053891 -
VAR_053892 -
VAR_053893 -

Structural Variations from Database of Genomic Variants (DGV) for FASTKD5 Gene

Variant ID Type Subtype PubMed ID
nsv833897 CNV Loss 17160897
nsv524482 CNV Gain 19592680
nsv833898 CNV Gain+Loss 17160897
nsv912604 CNV Loss 21882294
nsv912605 CNV Loss 21882294
nsv912606 CNV Loss 21882294
dgv4518n71 CNV Loss 21882294

Relevant External Links for FASTKD5 Gene

HapMap Linkage Disequilibrium report
FASTKD5

Disorders for FASTKD5 Gene

No disorders were found for FASTKD5 Gene.

No data available for UniProtKB/Swiss-Prot for FASTKD5 Gene

Publications for FASTKD5 Gene

  1. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11347906) Nagase T. … Ohara O. (DNA Res. 2001) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  4. Fast kinase domain-containing protein 3 is a mitochondrial protein essential for cellular respiration. (PMID: 20869947) Simarro M. … Anderson P. (Biochem. Biophys. Res. Commun. 2010) 3
  5. Exome sequencing supports a de novo mutational paradigm for schizophrenia. (PMID: 21822266) Xu B. … Karayiorgou M. (Nat. Genet. 2011) 3

Products for FASTKD5 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate FASTKD5
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat
  • Predesigned siRNA for gene silencing in human,mouse,rat for FASTKD5
  • Block miRNA regulation of FASTKD5 using miScript Target Protectors
  • antibodies-online proteins for FASTKD5
  • antibodies-online antibodies for FASTKD5
  • antibodies-online kits for FASTKD5

Sources for FASTKD5 Gene

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