This gene encodes a member of a small family of Fas-activated serine/threonine kinase domain (FASTKD) containing proteins that share an amino terminal mitochondrial targeting domain and multiple carboxy terminal FAST domains as well as a putative RNA-binding RAP domain. The members of this family are ubiquitously expressed and are generally most abundant in mitochondria-enriched tissues such as heart, skeletal muscle and brown-adipose tissue. Some members of this protein family may play a role in apoptosis. The protein encoded by this gene interacts with components of the mitochondrial respiratory and translation networks. A pseudogene of this gene is also present on chromosome 5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
GeneCards Summary for FASTKD3 Gene
FASTKD3 (FAST Kinase Domains 3) is a Protein Coding gene. GO annotations related to this gene include poly(A) RNA binding and protein kinase activity. An important paralog of this gene is TBRG4.
UniProtKB/Swiss-Prot for FASTKD3 Gene
Required for normal mitochondrial respiration.