Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FASTKD3 Gene

protein-coding   GIFtS: 49
GCID: GC05M007913

FAST Kinase Domains 3

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
FAST Kinase Domains 31 2
FAST Kinase Domain-Containing Protein 32

External Ids:    HGNC: 287581   Entrez Gene: 790722   Ensembl: ENSG000001242797   UniProtKB: Q14CZ73   
ORGUL members:         
NONCODE14:n410120      

Export aliases for FASTKD3 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FASTKD3 Gene:
This gene encodes a member of a small family of Fas-activated serine/threonine kinase domain (FASTKD) containing
proteins that share an amino terminal mitochondrial targeting domain and multiple carboxy terminal FAST domains
as well as a putative RNA-binding RAP domain. The members of this family are ubiquitously expressed and are
generally most abundant in mitochondria-enriched tissues such as heart, skeletal muscle and brown-adipose tissue.
Some members of this protein family may play a role in apoptosis. The protein encoded by this gene interacts with
components of the mitochondrial respiratory and translation networks. A pseudogene of this gene is also present
on chromosome 5. Alternative splicing results in multiple transcript variants. (provided by RefSeq, Jan 2013)

GeneCards Summary for FASTKD3 Gene: 
FASTKD3 (FAST kinase domains 3) is a protein-coding gene, and is affiliated with the lncRNA class. Diseases associated with FASTKD3 include encephalomyopathy, and mitochondrial encephalomyopathy. GO annotations related to this gene include protein kinase activity. An important paralog of this gene is FASTK.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.2  NT_006576.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FASTKD3 gene promoter:
         Nkx3-1   TBP   COUP-TF1   COUP   Nkx3-1 v1   HNF-4alpha2   HNF-4alpha1   COUP-TF   POU2F1   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFASTKD3 promoter sequence
   Search SABiosciences Chromatin IP Primers for FASTKD3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FASTKD3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5p15.31   Ensembl cytogenetic band:  5p15.31   HGNC cytogenetic band: 5p15.31

FASTKD3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FASTKD3 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M007913:  view genomic region     (about GC identifiers)

Start:
7,859,272 bp from pter      End:
7,869,150 bp from pter
Size:
9,879 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: FAKD3_HUMAN, Q14CZ7 (See protein sequence)
Recommended Name: FAST kinase domain-containing protein 3  
Size: 662 amino acids; 75689 Da
Secondary accessions: Q9BVD3

Explore the universe of human proteins at neXtProt for FASTKD3: NX_Q14CZ7

Explore proteomics data for FASTKD3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q14CZ7

  • FASTKD3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    FASTKD3 Protein Expression
    REFSEQ proteins: NP_076996.2  
    ENSEMBL proteins: 
     ENSP00000264669   ENSP00000424568   ENSP00000421798   ENSP00000426008   ENSP00000422443  

    Human Recombinant Protein Products for FASTKD3: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for FASTKD3
    GenScript Custom Purified and Recombinant Proteins Services for FASTKD3
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for FASTKD3 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--

    FASTKD3 for ontologies           About GeneDecksing



    FASTKD3 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for FASTKD3
    GenScript Custom Superior Antibodies Services for FASTKD3
    Novus Biologicals FASTKD3 Antibodies
    Abcam antibodies for FASTKD3
    Cloud-Clone Corp. Antibodies for FASTKD3 
    ThermoFisher Antibodies for FASTKD3
    LSBio Antibodies in human, mouse, rat for FASTKD3 

    Assay Products for FASTKD3: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for FASTKD3
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for FASTKD3
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for FASTKD3 
    Cloud-Clone Corp. CLIAs for FASTKD3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR010622 FAST_Leu-rich
     IPR013584 RAP
     IPR013579 FAST_2

    Graphical View of Domain Structure for InterPro Entry Q14CZ7

    ProtoNet protein and cluster: Q14CZ7

    UniProtKB/Swiss-Prot: FAKD3_HUMAN, Q14CZ7
    Similarity: Belongs to the FAST kinase family
    Similarity: Contains 1 RAP domain


    FASTKD3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004672protein kinase activity IEA--
         
    FASTKD3 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for FASTKD3:
     Decreased cell number  Decreased viability of wild-ty  Upregulation of NF-kappaB path 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for FASTKD3 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for FASTKD3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FASTKD3 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FASTKD3 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FASTKD3
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate FASTKD3
    SwitchGear 3'UTR luciferase reporter plasmidFASTKD3 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for FASTKD3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FASTKD3

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for FASTKD3
    Sirion Biotech Customized adenovirus for overexpression of FASTKD3

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for FASTKD3 (see all 8)
    OriGene ORF clones in mouse, rat for FASTKD3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FASTKD3 (NM_024091)
    Sino Biological Human cDNA Clone for FASTKD3
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FASTKD3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FASTKD3
    Sirion Biotech Customized lentivirus for stable overexpression of FASTKD3 
                         Customized lentivirus expression plasmids for stable overexpression of FASTKD3 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for FASTKD3
    Search LifeMap BioReagents cell lines for FASTKD3
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FASTKD3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FASTKD3

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0045333cellular respiration IMP--

    FASTKD3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FASTKD3 (FAKD3)

    Search CenterWatch for drugs/clinical trials and news about FASTKD3 / FAKD3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FASTKD3 gene: 
    NM_024091.3  

    Unigene Cluster for FASTKD3:

    FAST kinase domains 3
    Hs.653162  [show with all ESTs]
    Unigene Representative Sequence: AK026927
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000264669(uc011cmp.2 uc003jeb.3 uc003jec.3) ENST00000513658
    ENST00000282110 ENST00000511261 ENST00000507036 ENST00000513577 ENST00000504695
    ENST00000507572
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FASTKD3
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate FASTKD3
    SwitchGear 3'UTR luciferase reporter plasmidFASTKD3 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for FASTKD3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FASTKD3
    Clone
    Products:
         
    OriGene clones in human, mouse for FASTKD3 (see all 8)
    OriGene ORF clones in mouse, rat for FASTKD3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FASTKD3 (NM_024091)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FASTKD3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FASTKD3
    Sirion Biotech Customized lentivirus for stable overexpression of FASTKD3 
                         Customized lentivirus expression plasmids for stable overexpression of FASTKD3 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for FASTKD3
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FASTKD3
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FASTKD3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FASTKD3

    Additional mRNA sequence: 

    AF161354.1 AK026927.1 BC001295.1 BC113563.1 BC143517.1 BC143518.1 NR_036553.1 NR_073608.1 

    5 DOTS entries:

    DT.452488  DT.100751602  DT.92423121  DT.92423122  DT.412473 

    24/61 AceView cDNA sequences (see all 61):

    BU624105 AI399857 BI964729 CK903403 BQ921348 NM_024091 BQ050729 AI151134 
    BG613096 AA314900 AK026927 BX406626 AW269782 BX342241 BG615709 BG613049 
    BG388682 BX406627 AF161354 BX478397 BM688841 AL707167 AI041749 AW014916 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for FASTKD3 (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c · 2d · 2e · 2f ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b · 7c
    SP1:              -     -     -     -     -     -           -                                                   
    SP2:              -     -     -     -     -     -           -           -                                       
    SP3:                                                        -           -                                       
    SP4:                                                                                                            
    SP5:              -     -                                                                                       


    ECgene alternative splicing isoforms for FASTKD3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FASTKD3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGCTGTAAAG
    FASTKD3 Expression
    About this image


    See FASTKD3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FASTKD3

    SOURCE GeneReport for Unigene cluster: Hs.653162
        SABiosciences Custom PCR Arrays for FASTKD3
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for FASTKD3
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FASTKD3
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FASTKD3
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FASTKD3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FASTKD3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for FASTKD3 gene from 5/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fastkd31 , 5 FAST kinase domains 31, 5 74.15(n)1
    64.95(a)1
      13 (35.55 cM)5
    695771  NM_027123.41  NP_081399.31 
     685822485 
    chicken
    (Gallus gallus)
    Aves FASTKD31 FAST kinase domains 3 62.76(n)
    53.33(a)
      420932  XM_419017.3  XP_419017.2 
    lizard
    (Anolis carolinensis)
    Reptilia FASTKD36
    FAST kinase domains 3
    47(a)
    1 ↔ 1
    4(82543653-82556692)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.190382 Xenopus laevis transcribed sequence with weak similarity more 72.96(n)    AW639711.1 
    zebrafish
    (Danio rerio)
    Actinopterygii fastkd31 FAST kinase domains 3 51.93(n)
    45.29(a)
      100003734  XM_001338215.3  XP_001338251.1 


    ENSEMBL Gene Tree for FASTKD3 (if available)
    TreeFam Gene Tree for FASTKD3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FASTKD3 gene
    FASTK2  TBRG42  FASTKD12  

    FASTKD3 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for FASTKD3
    PGOHUM00000251285


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/192 SNPs in FASTKD3 are shown (see all 192)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0361614
    A breast cancer sample4--see VAR_0361612 L V mis40--------
    VAR_0577694
    ----see VAR_0577692 L F mis40--------
    VAR_0318094
    ----see VAR_0318092 K R mis40--------
    rs40019651,2
    C--7820552(-) GTTTGATTG/-  
            
    GAGGG
    3 -- ds50011Minor allele frequency- -:0.50CSA 2
    rs171838281,2
    C,F--7820651(+) AACCAG/CAAGAT 3 -- ds50013Minor allele frequency- C:0.01NA 142
    rs744977541,2
    C,F--7820702(+) GTACTC/GTATTT 3 -- ds50011Minor allele frequency- G:0.16WA 118
    rs1816592961,2
    --7820725(+) TTTCCC/TTACGG 3 -- ds50010--------
    rs1857916431,2
    --7820881(+) CTTTAC/TAGCAC 3 -- ut31 nc-transcript-variant0--------
    rs10460141,2
    C,F,A,H--7821007(-) TGGTGA/GTCTGA 3 -- ut31 nc-transcript-variant27Minor allele frequency- G:0.22MN EA NA NS WA 3150
    rs2014449101,2
    --7821086(+) AATGCA/GAGTTC 3 -- ut31 nc-transcript-variant0--------

    HapMap Linkage Disequilibrium report for FASTKD3 (7859272 - 7869150 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for FASTKD3:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv268361CNV Insertion20981092
    esv274651CNV Insertion20981092

    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing FASTKD3
    DNA2.0 Custom Variant and Variant Library Synthesis for FASTKD3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for FASTKD3:    About MalaCards
    encephalomyopathy    mitochondrial encephalomyopathy

    1 disease from the University of Copenhagen DISEASES database for FASTKD3:
    Mitochondrial encephalomyopathy

    FASTKD3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): FASTKD3
    Human Genome Epidemiology (HuGE) Navigator: FASTKD3 (4 documents)

    Export disorders for FASTKD3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FASTKD3 gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with FASTKD3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    3. Proteomic dissection of the von Hippel-Lindau (VHL) i nteractome. (PubMed id 21942715)1 Lai Y....Shiio Y. (2011)
    4. Single-nucleotide polymorphisms, acute rejection, and severity of tubulitis in kidney transplantation, accounting for center-to-center variation. (PubMed id 21085059)4 Israni A....Oetting W.S. (2010)
    5. Fast kinase domain-containing protein 3 is a mitochon drial protein essential for cellular respiration. (PubMed id 20869947)1 Simarro M....Anderson P. (2010)
    6. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
    7. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
    8. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    9. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (2004)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 79072 HGNC: 28758 AceView: MGC5297 Ensembl:ENSG00000124279 euGenes: HUgn79072
    ECgene: FASTKD3 H-InvDB: FASTKD3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FASTKD3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for FASTKD3 gene:
    Search GeneIP for patents involving FASTKD3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for FASTKD3  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for FASTKD3  
     OriGene qSTAR qPCR primer pairs in human, mouse for FASTKD3   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for FASTKD3   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for FASTKD3   OriGene Custom Protein Services for FASTKD3  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FASTKD3
     QIAGEN SeqTarget long-range PCR primers for resequencing FASTKD3
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FASTKD3
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FASTKD3
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FASTKD3
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FASTKD3
     GenScript Custom Purified and Recombinant Proteins Services for FASTKD3 GenScript cDNA clones with any tag delivered in your preferred vector for FASTKD3
     GenScript Custom Assay Services for FASTKD3 GenScript Custom Superior Antibodies Services for FASTKD3
     GenScript Custom overexpressing Cell Line Services for FASTKD3 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in FASTKD3 promoter
     Search Chromatin IP Primers for FASTKD3
     RT2 qPCR Primer Assay in human, mouse, rat FASTKD3
     Search GNC Networks for FASTKD3
     SABiosciences Custom PCR Arrays for FASTKD3
     Search Tocris compounds for FASTKD3 (FAKD3)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     cDNA Clones for FASTKD3
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     FASTKD3 antibodies
     Antibodies for FASTKD3
     See all of Abcam's Antibodies, Kits and Proteins for FASTKD3
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for FASTKD3
     Antibodies for FASTKD3
     ELISAs for FASTKD3
     CLIAs for FASTKD3
     Search LifeMap BioReagents cell lines for FASTKD3
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FASTKD3
     SwitchGear 3'UTR luciferase reporter plasmids for FASTKD3
     SwitchGear Promoter luciferase reporter plasmids for FASTKD3
     ThermoFisher Antibodies for FASTKD3
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FASTKD3
     inGenious Targeting Laboratory - Custom generated mouse model solutions for FASTKD3
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for FASTKD3
    Customized:
     lentivirus for stable overexpression of FASTKD3
     lentivirus expression plasmids for stable overexpression of FASTKD3
     adenovirus for overexpression of FASTKD3
     LSBio Antibodies in human, mouse, rat for FASTKD3
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      FASTKD3 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4