Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



FASTKD3 Gene

protein-coding   GIFtS: 49
GCID: GC05M007913

FAST Kinase Domains 3

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
FAST Kinase Domains 31 2
FAST Kinase Domain-Containing Protein 32

External Ids:    HGNC: 287581   Entrez Gene: 790722   Ensembl: ENSG000001242797   UniProtKB: Q14CZ73   
ORGUL members:         

Export aliases for FASTKD3 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for FASTKD3 Gene:
This gene encodes a member of a small family of Fas-activated serine/threonine kinase domain (FASTKD) containing
proteins that share an amino terminal mitochondrial targeting domain and multiple carboxy terminal FAST domains
as well as a putative RNA-binding RAP domain. The members of this family are ubiquitously expressed and are
generally most abundant in mitochondria-enriched tissues such as heart, skeletal muscle and brown-adipose tissue.
Some members of this protein family may play a role in apoptosis. The protein encoded by this gene interacts with
components of the mitochondrial respiratory and translation networks. A pseudogene of this gene is also present
on chromosome 5. Alternative splicing results in multiple transcript variants. (provided by RefSeq, Jan 2013)

GeneCards Summary for FASTKD3 Gene:
FASTKD3 (FAST kinase domains 3) is a protein-coding gene. GO annotations related to this gene include protein kinase activity. An important paralog of this gene is FASTK.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000005.9  NT_006576.17  NC_018916.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the FASTKD3 gene promoter:
         Nkx3-1   TBP   COUP-TF1   COUP   Nkx3-1 v1   HNF-4alpha2   HNF-4alpha1   COUP-TF   POU2F1   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFASTKD3 promoter sequence
   Search Chromatin IP Primers for FASTKD3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FASTKD3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5p15.31   Ensembl cytogenetic band:  5p15.31   HGNC cytogenetic band: 5p15.31

FASTKD3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FASTKD3 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M007913:  view genomic region     (about GC identifiers)

Start:
7,859,272 bp from pter      End:
7,869,150 bp from pter
Size:
9,879 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: FAKD3_HUMAN, Q14CZ7 (See protein sequence)
Recommended Name: FAST kinase domain-containing protein 3  
Size: 662 amino acids; 75689 Da
Secondary accessions: Q9BVD3

Explore the universe of human proteins at neXtProt for FASTKD3: NX_Q14CZ7

Explore proteomics data for FASTKD3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See FASTKD3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_076996.2  
    ENSEMBL proteins: 
     ENSP00000264669   ENSP00000424568   ENSP00000421798   ENSP00000426008   ENSP00000422443  

    FASTKD3 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for FASTKD3
    GenScript Custom Purified and Recombinant Proteins Services for FASTKD3
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for FASTKD3

     
    Search eBioscience for Proteins for FASTKD3 

    FASTKD3 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for FASTKD3
    OriGene Custom Antibody Services for FASTKD3
    Novus Biologicals FASTKD3 Antibodies
    Abcam antibodies for FASTKD3
    Cloud-Clone Corp. Antibodies for FASTKD3
    ThermoFisher Antibodies for FASTKD3
    LSBio Antibodies in human, mouse, rat for FASTKD3

    FASTKD3 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for FASTKD3
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for FASTKD3
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for FASTKD3
    Cloud-Clone Corp. CLIAs for FASTKD3
    Search eBioscience for ELISAs for FASTKD3 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    3 InterPro protein domains:
     IPR010622 FAST_Leu-rich
     IPR013584 RAP
     IPR013579 FAST_2

    Graphical View of Domain Structure for InterPro Entry Q14CZ7

    ProtoNet protein and cluster: Q14CZ7

    UniProtKB/Swiss-Prot: FAKD3_HUMAN, Q14CZ7
    Similarity: Belongs to the FAST kinase family
    Similarity: Contains 1 RAP domain


    Find genes that share domains with FASTKD3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004672protein kinase activity IEA--
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with FASTKD3           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for FASTKD3:
     Decreased cell number  Decreased viability of wild-ty  Upregulation of NF-kappaB path 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FASTKD3
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FASTKD3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FASTKD3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FASTKD3

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat FASTKD3 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate FASTKD3
    SwitchGear 3'UTR luciferase reporter plasmidFASTKD3 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for FASTKD3
    Predesigned siRNA for gene silencing in human, mouse, rat FASTKD3

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for FASTKD3

    Clone
    Products:
         
    OriGene clones in human, mouse for FASTKD3 (see all 7)
    OriGene ORF clones in mouse, rat for FASTKD3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FASTKD3 (NM_024091)
    Sino Biological Human cDNA Clone for FASTKD3
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FASTKD3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FASTKD3

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for FASTKD3
    Browse ESI BIO Cell Lines and PureStem Progenitors for FASTKD3 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FASTKD3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    nucleus2
    cytosol1
    peroxisome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--

    Find genes that share ontologies with FASTKD3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus




        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FASTKD3
    Interactions:

        Search GeneGlobe Interaction Network for FASTKD3

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0045333cellular respiration IMP--

    Find genes that share ontologies with FASTKD3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FASTKD3 (FAKD3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for FASTKD3 gene: 
    NM_024091.3  

    Unigene Cluster for FASTKD3:

    FAST kinase domains 3
    Hs.653162  [show with all ESTs]
    Unigene Representative Sequence: AK026927
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000264669(uc011cmp.2 uc003jeb.3 uc003jec.3) ENST00000513658
    ENST00000282110 ENST00000511261 ENST00000507036 ENST00000513577 ENST00000504695
    ENST00000507572
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat FASTKD3 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate FASTKD3
    SwitchGear 3'UTR luciferase reporter plasmidFASTKD3 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for FASTKD3
    Predesigned siRNA for gene silencing in human, mouse, rat FASTKD3
    Clone
    Products:
         
    OriGene clones in human, mouse for FASTKD3 (see all 7)
    OriGene ORF clones in mouse, rat for FASTKD3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FASTKD3 (NM_024091)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FASTKD3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FASTKD3
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for FASTKD3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FASTKD3
      QuantiTect SYBR Green Assays in human, mouse, rat FASTKD3
      QuantiFast Probe-based Assays in human, mouse, rat FASTKD3

    Additional mRNA sequence: 

    AF161354.1 AK026927.1 BC001295.1 BC113563.1 BC143517.1 BC143518.1 NR_036553.1 NR_073608.1 

    5 DOTS entries:

    DT.452488  DT.100751602  DT.92423121  DT.92423122  DT.412473 

    Selected AceView cDNA sequences (see all 61):

    BQ921348 BI964729 BQ050729 BU624105 CK903403 NM_024091 AI399857 AI151134 
    BG533707 BI754398 AL707167 AA316122 BX478397 AF161354 BX342241 BX479725 
    BG388682 AL557123 BG499460 BG613049 BG613096 AI041749 BE537873 AK026927 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for FASTKD3 (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c · 2d · 2e · 2f ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b · 7c
    SP1:              -     -     -     -     -     -           -                                                   
    SP2:              -     -     -     -     -     -           -           -                                       
    SP3:                                                        -           -                                       
    SP4:                                                                                                            
    SP5:              -     -                                                                                       


    ECgene alternative splicing isoforms for FASTKD3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    FASTKD3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGCTGTAAAG
    FASTKD3 Expression
    About this image

    FASTKD3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FASTKD3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.653162
        Custom PCR Arrays for FASTKD3
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for FASTKD3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FASTKD3
    QuantiTect SYBR Green Assays in human, mouse, rat FASTKD3
    QuantiFast Probe-based Assays in human, mouse, rat FASTKD3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FASTKD3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for FASTKD3 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fastkd31 , 5 FAST kinase domains 31, 5 74.15(n)1
    64.95(a)1
      13 (35.55 cM)5
    695771  NM_027123.41  NP_081399.31 
     685822485 
    chicken
    (Gallus gallus)
    Aves FASTKD31 FAST kinase domains 3 62.76(n)
    53.33(a)
      420932  XM_419017.4  XP_419017.3 
    lizard
    (Anolis carolinensis)
    Reptilia FASTKD36
    FAST kinase domains 3
    48(a)
    1 ↔ 1
    4(82543653-82556692)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.190382 Xenopus laevis transcribed sequence with weak similarity more 72.96(n)    AW639711.1 
    zebrafish
    (Danio rerio)
    Actinopterygii fastkd31 FAST kinase domains 3 51.93(n)
    45.29(a)
      100003734  XM_001338215.4  XP_001338251.1 


    ENSEMBL Gene Tree for FASTKD3 (if available)
    TreeFam Gene Tree for FASTKD3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for FASTKD3 gene
    FASTK2  TBRG42  FASTKD12  

    Find genes that share paralogs with FASTKD3           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for FASTKD3
    PGOHUM00000251285


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for FASTKD3 (see all 192)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0361614
    A breast cancer sample4--see VAR_0361612 L V mis40--------
    rs40019651,2
    C--7820552(-) GTTTGATTG/-  
            
    GAGGG
    3 -- ds50011Minor allele frequency- -:0.50CSA 2
    rs171838281,2
    C,F--7820651(+) AACCAG/CAAGAT 3 -- ds50013Minor allele frequency- C:0.01NA 142
    rs744977541,2
    C,F--7820702(+) GTACTC/GTATTT 3 -- ds50011Minor allele frequency- G:0.16WA 118
    rs1816592961,2
    --7820725(+) TTTCCC/TTACGG 3 -- ds50010--------
    rs1857916431,2
    --7820881(+) CTTTAC/TAGCAC 3 -- ut31 nc-transcript-variant0--------
    rs10460141,2
    C,F,A,H--7821007(-) TGGTGA/GTCTGA 3 -- ut31 nc-transcript-variant27Minor allele frequency- G:0.22MN EA NA NS WA 3150
    rs2014449101,2
    --7821086(+) AATGCA/GAGTTC 3 -- ut31 nc-transcript-variant0--------
    rs10460121,2
    C,F,H--7821096(-) AACAAT/CGGAAG 3 -- ut31 nc-transcript-variantese323Minor allele frequency- C:0.23MN NA NS EA WA CSA 2550
    rs168792361,2
    C,F,H--7821275(+) TGAGGT/GTCCTC 3 -- int120Minor allele frequency- G:0.15NA NS EA WA CSA 2192

    HapMap Linkage Disequilibrium report for FASTKD3 (7859272 - 7869150 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for FASTKD3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv268361CNV Insertion20981092
    esv274651CNV Insertion20981092

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing FASTKD3
    DNA2.0 Custom Variant and Variant Library Synthesis for FASTKD3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    1 disease from the University of Copenhagen DISEASES database for FASTKD3:
    Mitochondrial encephalomyopathy

    Find genes that share disorders with FASTKD3           About GenesLikeMe

    Genetic Association Database (GAD): FASTKD3
    Human Genome Epidemiology (HuGE) Navigator: FASTKD3 (4 documents)

    Export disorders for FASTKD3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for FASTKD3 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with FASTKD3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    3. Proteomic dissection of the von Hippel-Lindau (VHL) interactome. (PubMed id 21942715)1 Lai Y....Shiio Y. (J. Proteome Res. 2011)
    4. Single-nucleotide polymorphisms, acute rejection, and severity of tubulitis in kidney transplantation, accounting for center-to-center variation. (PubMed id 21085059)4 Israni A....Oetting W.S. (Transplantation 2010)
    5. Fast kinase domain-containing protein 3 is a mitochondrial protein essential for cellular respiration. (PubMed id 20869947)1 Simarro M....Anderson P. (Biochem. Biophys. Res. Commun. 2010)
    6. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (Am. J. Hum. Genet. 2009)
    7. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (Science 2006)
    8. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    9. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (Genome Res. 2004)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 79072 HGNC: 28758 AceView: MGC5297 Ensembl:ENSG00000124279 euGenes: HUgn79072
    ECgene: FASTKD3 H-InvDB: FASTKD3

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for FASTKD3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for FASTKD3 gene:
    Search GeneIP for patents involving FASTKD3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for FASTKD3   OriGene RNAi products in human, mouse, rat for FASTKD3  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for FASTKD3  
     OriGene qSTAR qPCR primer pairs in human, mouse for FASTKD3   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for FASTKD3   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for FASTKD3   OriGene Custom Protein Services for FASTKD3  

     
     
     Block miRNA regulation of human, mouse, rat FASTKD3 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing FASTKD3
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FASTKD3 Predesigned siRNA for gene silencing in human, mouse, rat FASTKD3
     QuantiFast Probe-based Assays in human, mouse, rat FASTKD3 QuantiTect SYBR Green Assays in human, mouse, rat FASTKD3
     Custom PCR Arrays for FASTKD3 Search Chromatin IP Primers for FASTKD3
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FASTKD3  Search GeneGlobe Interaction Network for FASTKD3
     Regulatory tfbs in FASTKD3 promoter
     GenScript Custom Purified and Recombinant Proteins Services for FASTKD3 GenScript cDNA clones with any tag delivered in your preferred vector for FASTKD3
     GenScript Custom Assay Services for FASTKD3 GenScript Custom overexpressing Cell Line Services for FASTKD3
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for FASTKD3 (FAKD3)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for FASTKD3
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     FASTKD3 antibodies
     Antibodies for FASTKD3
     See all of Abcam's Antibodies, Kits and Proteins for FASTKD3
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for FASTKD3
     Antibodies for FASTKD3
     ELISAs for FASTKD3
     CLIAs for FASTKD3



     Browse ESI BIO Cell Lines and PureStem Progenitors for FASTKD3
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FASTKD3
     SwitchGear 3'UTR luciferase reporter plasmids for FASTKD3
     SwitchGear Promoter luciferase reporter plasmids for FASTKD3
     ThermoFisher Antibodies for FASTKD3
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FASTKD3
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FASTKD3
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FASTKD3
     LSBio Antibodies in human, mouse, rat for FASTKD3
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for FASTKD3
      Search eBioscience for proteins for FASTKD3
      Search eBioscience for elisas for FASTKD3
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      FASTKD3 gene at Home site.
    Version: 3.12.224 13 Oct 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4