Aliases for FASTK Gene
Aliases for FASTK Gene
External Ids for FASTK Gene
- HGNC: 24676
- Entrez Gene: 10922
- Ensembl: ENSG00000164896
- OMIM: 606965
- UniProtKB: Q14296
Previous GeneCards Identifiers for FASTK Gene
- GC07M149020
- GC07M150088
- GC07M150165
- GC07M150211
- GC07M150404
- GC07M150773
- GC07M144586
Summaries for FASTK Gene
-
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for FASTK Gene
FASTK (Fas Activated Serine/Threonine Kinase) is a Protein Coding gene. GO annotations related to this gene include protein kinase activity and Fas-activated serine/threonine kinase activity. An important paralog of this gene is FASTKD3.
UniProtKB/Swiss-Prot for FASTK Gene
-
Phosphorylates the splicing regulator TIA1, thereby promoting the inclusion of FAS exon 6, which leads to an mRNA encoding a pro-apoptotic form of the receptor.
-
Isoform 4: Required for the biogenesis of some mitochondrial-encoded mRNAs, specifically stabilizes ND6 (NADH dehydrogenase complex subunit 6) mRNA, and regulates its levels.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FASTK Gene
Genomics for FASTK Gene
Regulatory Elements for FASTK Gene
Enhancers for FASTK Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FASTK on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the FASTK gene promoter:
Regulatory Element Products
Genomic Location for FASTK Gene
- Chromosome:
- 7
- Start:
- 151,076,593 bp from pter
- End:
- 151,080,883 bp from pter
- Size:
- 4,291 bases
- Orientation:
- Minus strand
Genomic View for FASTK Gene
Genes around FASTK on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 7q36.1 by Ensembl
- 7q36.1 by Entrez Gene
- 7q36.1 by HGNC
FASTK Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FASTK Gene
Proteins for FASTK Gene
-
Protein details for FASTK Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q14296-FASTK_HUMAN
- Recommended name:
- Fas-activated serine/threonine kinase
- Protein Accession:
- Q14296
- A8K867
- F8VTW9
- Q59EM8
- Q8IVA0
Protein attributes for FASTK Gene
- Size:
- 549 amino acids
- Molecular mass:
- 61104 Da
- Quaternary structure:
-
- Interacts with TIA-1 and TIAR.
- SequenceCaution:
-
- Sequence=BAD93020.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
Protein Expression for FASTK Gene
Post-translational modifications for FASTK Gene
- Autophosphorylated on serine/threonine residues. Activated by dephosphorylation.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for FASTK Gene
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for FASTK
- Novus Biologicals Antibodies for FASTK
-
Cloud-Clone Corp. Antibodies for FASTK
- Invitrogen Antibodies for FASTK
- antibodies-online Antibodies for FASTK: See all 77
- GeneTex FASTK antibody for FASTK
-
Santa Cruz Biotechnology (SCBT) Antibodies for FASTK
Protein Products
-
OriGene Purified Proteins for FASTK
- Search Origene for MassSpec and Protein Over-expression Lysates for FASTK
- Origene Custom Protein Services for FASTK
-
Cloud-Clone Corp. Proteins for FASTK
- antibodies-online Proteins for FASTK: See all 5
- Search antibodies-online for peptides
- Search GeneTex for Proteins for FASTK
Assay Products
- antibodies-online Kits for FASTK: See all 2
No data available for DME Specific Peptides for FASTK Gene
Domains & Families for FASTK Gene
Protein Domains for FASTK Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for FASTK Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q14296UniProtKB/Swiss-Prot:
FASTK_HUMAN :- The RAP domain is essential for RNA-binding.
- Belongs to the FAST protein kinase family.
- Domain:
-
- The RAP domain is essential for RNA-binding.
- Family:
-
- Belongs to the FAST protein kinase family.
No data available for Gene Families for FASTK Gene
Function for FASTK Gene
Molecular function for FASTK Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- ATP + [Fas-activated serine/threonine protein] = ADP + [Fas-activated serine/threonine phosphoprotein].
- UniProtKB/Swiss-Prot Function:
- Phosphorylates the splicing regulator TIA1, thereby promoting the inclusion of FAS exon 6, which leads to an mRNA encoding a pro-apoptotic form of the receptor.
- UniProtKB/Swiss-Prot Function:
- Isoform 4: Required for the biogenesis of some mitochondrial-encoded mRNAs, specifically stabilizes ND6 (NADH dehydrogenase complex subunit 6) mRNA, and regulates its levels.
Enzyme Numbers (IUBMB) for FASTK Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA | -- |
| GO:0004672 | protein kinase activity | IEA | -- |
| GO:0004674 | protein serine/threonine kinase activity | IEA,IDA | 7544399 |
| GO:0005515 | protein binding | IPI | 7544399 |
| GO:0005524 | ATP binding | IEA | -- |
Phenotypes for FASTK Gene
- MGI mutant phenotypes for FASTK:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for FASTK:
-
- Increased viability
- Increased vaccinia virus (VACV) infection
- Decreased hepcidin::fluc mRNA expression
- shRNA abundance <= 50%
- Decreased viability in esophageal squamous lineage
- Dynamic nuclei (hole, folded or small irregular)
- Decreased NF-kappaB reporter expression
- Decreased viability
- Synthetic lethal with MLN4924 (a NAE inhibitor)
- Decreased cell migration
- Synthetic lethal with vaccinia virus (VACV) infection
- Increased viability with MLN4924 (a NAE inhibitor)
- Decreased human cytomegalovirus (HCMV) strain AD169 replication
- Increased cell migration
Animal Models for FASTK Gene
- MGI Knock Outs for FASTK:
-
- Fastk tm1.1Andp
Animal Model Products
-
Taconic Biosciences Mouse Models for FASTK
-
ViGene Biosciences lentiviral particle packaged cDNA for FASTK gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FASTK gene
- Search ViGene Biosciences for FASTK
CRISPR Products
-
OriGene CRISPR knockouts for FASTK
-
Santa Cruz Biotechnology (SCBT) CRISPR for FASTK
- GenScript: Design CRISPR guide RNA sequences for FASTK
miRNA for FASTK Gene
- miRTarBase miRNAs that target FASTK
-
- hsa-mir-331-3p (MIRT043485)
- hsa-mir-185-5p (MIRT045322)
- hsa-mir-106a-5p (MIRT054367)
- hsa-mir-6796-5p (MIRT486231)
- hsa-mir-6763-5p (MIRT486232)
- hsa-mir-3150a-3p (MIRT486233)
- hsa-mir-6742-5p (MIRT486234)
- hsa-mir-4447 (MIRT486235)
- hsa-mir-4472 (MIRT486236)
- hsa-mir-3151-5p (MIRT486237)
- hsa-mir-491-5p (MIRT486238)
- hsa-mir-6825-5p (MIRT486239)
- hsa-mir-939-5p (MIRT486240)
- hsa-mir-1343-5p (MIRT486241)
- hsa-mir-3175 (MIRT486242)
- hsa-mir-8085 (MIRT486243)
- hsa-mir-6731-5p (MIRT486244)
- hsa-mir-4736 (MIRT486245)
- hsa-mir-6820-5p (MIRT486246)
- hsa-mir-657 (MIRT486247)
- hsa-mir-4784 (MIRT486248)
- hsa-mir-3150b-3p (MIRT486249)
- hsa-mir-3141 (MIRT486250)
- hsa-mir-134-3p (MIRT486251)
miRNA Products
- Search ViGene Biosciences for FASTK
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FASTK
- Browse OriGene Inhibitory RNA Products For FASTK
-
ViGene Biosciences ready-to-package AAV shRNAs for FASTK gene
Clone Products
- Sino Biological Human cDNA Clone for FASTK
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for FASTK
Cell Line Products
-
Horizon Cell Lines for FASTK
-
ViGene Biosciences adenoviral particle packaged cDNA for FASTK gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FASTK gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FASTK gene
Flow Cytometry Products
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for FASTK Gene
Localization for FASTK Gene
Subcellular locations from UniProtKB/Swiss-Prot for FASTK Gene
- Isoform 4: Mitochondrion matrix. Note=Colocalizes with mitochondrial RNA granules. {ECO:0000269 PubMed:25704814}.
| Compartment | Confidence |
|---|---|
| mitochondrion | 5 |
| nucleus | 3 |
| cytosol | 2 |
| plasma membrane | 1 |
| peroxisome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005739 | mitochondrion | IEA | -- |
| GO:0005759 | mitochondrial matrix | IEA | -- |
Pathways & Interactions for FASTK Gene
No Data Available
Interacting Proteins for FASTK Gene
Selected Interacting proteins:
Q14296-FASTK_HUMAN
ENSP00000297532
for FASTK Gene via
IID
STRING
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006468 | protein phosphorylation | IDA,IEA | 7544399 |
| GO:0006915 | apoptotic process | IEA | -- |
| GO:0016310 | phosphorylation | IEA | -- |
| GO:0043484 | regulation of RNA splicing | IMP | 17592127 |
| GO:0097190 | apoptotic signaling pathway | TAS | 7544399 |
No data available for Pathways by source and SIGNOR curated interactions for FASTK Gene
Transcripts for FASTK Gene
mRNA/cDNA for FASTK Gene
- (11) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (631) Selected AceView cDNA sequences:
- (17) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FASTK Gene
CRISPR Products
-
OriGene CRISPR knockouts for FASTK
-
Santa Cruz Biotechnology (SCBT) CRISPR for FASTK
- GenScript: Design CRISPR guide RNA sequences for FASTK
miRNA Products
- Search ViGene Biosciences for FASTK
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FASTK
- Browse OriGene Inhibitory RNA Products For FASTK
-
ViGene Biosciences ready-to-package AAV shRNAs for FASTK gene
Clone Products
- Sino Biological Human cDNA Clone for FASTK
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for FASTK
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | · | 1f | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | · | 3d | · | 3e | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | ^ | 10a | · | 10b | ^ | 11 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP12: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP13: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP14: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP15: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP16: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP17: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP18: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP19: |
| ExUns: | 12a | · | 12b |
|---|---|---|---|
| SP1: | |||
| SP2: | |||
| SP3: | |||
| SP4: | |||
| SP5: | |||
| SP6: | |||
| SP7: | |||
| SP8: | |||
| SP9: | |||
| SP10: | |||
| SP11: | |||
| SP12: | |||
| SP13: | |||
| SP14: | |||
| SP15: | |||
| SP16: | |||
| SP17: | |||
| SP18: | |||
| SP19: |
Expression for FASTK Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
-
Heart (Cardiovascular System)
- Atrioventricular Canal Cells Atrioventricular Canal
- Outflow Tract
-
Testis (Reproductive System)
- Leydig Cells Testis Interstitium
- Thyroid (Endocrine System)
- Intestine (Gastrointestinal Tract)
- Pancreas (Endocrine System)
This gene is overexpressed in Liver (65.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for FASTK Gene
NURSA nuclear receptor signaling pathways regulating expression of FASTK Gene:
FASTKSOURCE GeneReport for Unigene cluster for FASTK Gene:
Hs.647094mRNA Expression by UniProt/SwissProt for FASTK Gene:
Q14296-FASTK_HUMAN
Tissue specificity:
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Evidence on tissue expression from TISSUES for FASTK Gene
- Nervous system(4.9)
- Skin(4.3)
- Blood(4.1)
Primer Products
-
OriGene qPCR primer pairs for FASTK
-
OriGene qPCR primer pairs and template standards for FASTK
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for FASTK Gene
Orthologs for FASTK Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FASTK 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | FASTK 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | FASTK 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Fastk 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Fastk 34 16 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | FASTK 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | FASTK 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | FASTK 35 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | fastk 34 35 |
|
||
| Dr.13216 34 |
|
- Species where no ortholog for FASTK was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for FASTK Gene
(1) SIMAP similar genes for FASTK Gene using alignment to 3 proteins:
Variants for FASTK Gene
| SNP ID | Clin | Chr 07 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs758691941 | A lung adenocarcinoma sample | 151,077,331(+) | AGGCA(A/C/T)AGTCA | reference, missense | |
| rs1000693573 | -- | 151,080,811(+) | AGATA(A/G)CCGCC | intron-variant, upstream-variant-2KB, utr-variant-5-prime | |
| rs1001244461 | -- | 151,080,086(+) | CCACG(C/T)CTTTG | intron-variant | |
| rs1001512726 | -- | 151,080,781(+) | ACCGA(A/G)TCCGC | intron-variant, utr-variant-5-prime | |
| rs1001844773 | -- | 151,079,321(+) | CTAGC(C/G)AGGCC | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv11724n54 | CNV | loss | 21841781 |
| dgv3695n106 | OTHER | inversion | 24896259 |
| dgv6756n100 | CNV | gain | 25217958 |
| nsv1067934 | OTHER | inversion | 25765185 |
| nsv1151906 | OTHER | inversion | 26484159 |
| nsv465215 | CNV | loss | 19166990 |
| nsv517508 | CNV | loss | 19592680 |
| nsv526410 | CNV | loss | 19592680 |
| nsv6004 | CNV | insertion | 18451855 |
| nsv831188 | CNV | loss | 17160897 |
| nsv951648 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
46% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.67;
65.88% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FASTK Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- FASTK
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FASTK Gene
Disorders for FASTK Gene
Relevant External Links for FASTK
No disorders were found for FASTK Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FASTK Gene
Publications for FASTK Gene
- Fas-activated serine/threonine kinase (FAST) phosphorylates TIA-1 during Fas-mediated apoptosis. (PMID: 7544399) Tian Q. … Anderson P. (J. Exp. Med. 1995) 2 3 4 22 64
- FAST is a survival protein that senses mitochondrial stress and modulates TIA-1-regulated changes in protein expression. (PMID: 15572676) Li W. … Anderson P. (Mol. Cell. Biol. 2004) 2 3 22 64
- A mitochondria-specific isoform of FASTK is present in mitochondrial RNA granules and regulates gene expression and function. (PMID: 25704814) Jourdain A.A. … Martinou J.C. (Cell Rep 2015) 3 4 64
- Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3 46 64
- A common variant in DRD3 receptor is associated with autism spectrum disorder. (PMID: 19058789) de Krom M. … van Ree J.M. (Biol. Psychiatry 2009) 3 46 64
Products for FASTK Gene
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- Novus Biologicals Antibodies for FASTK
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- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Cloud-Clone Corp. Antibodies for FASTK
- Cloud-Clone Corp. Proteins for FASTK
- Browse Assay Kits at Cloud-Clone Corp.
- Taconic Biosciences Mouse Models for FASTK
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Addgene plasmids for FASTK
- antibodies-online Antibodies for FASTK: See all 77
- antibodies-online Kits for FASTK: See all 2
- antibodies-online Proteins for FASTK: See all 5
- Search antibodies-online for peptides
- GeneTex FASTK antibody for FASTK
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- ViGene Biosciences adenoviral particle packaged cDNA for FASTK gene
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- Search ViGene Biosciences for FASTK
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- Horizon Cell Lines for FASTK
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- VectorBuilder custom plasmid, inducible vectors for FASTK
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- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FASTK Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer