Aliases for FARP2 Gene
External Ids for FARP2 Gene
GeneCards Summary for FARP2 Gene
FARP2 (FERM, RhoGEF And Pleckstrin Domain Protein 2) is a Protein Coding gene. Among its related pathways are Ras signaling pathway and L1CAM interactions. GO annotations related to this gene include phospholipid binding and cytoskeletal protein binding. An important paralog of this gene is FRMD3.
UniProtKB/Swiss-Prot for FARP2 Gene
Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion (By similarity).