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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

FAR2 Gene

protein-coding GIFtS: 54
GCID: GC12P029302

fatty acyl CoA reductase 2

(Previous name: male sterility domain containing 1 )
(Previous symbol: MLSTD1)

Explore 4 diseases affiliated with
FAR2 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Fatty Acyl CoA Reductase 2¹ ²		FLJ10462¹
MLSTD1¹ ² ³		Male Sterility Domain Containing 1¹
SDR10E2¹ ²		Fatty Acyl-CoA Reductase 2²
Male Sterility Domain-Containing Protein 1² ³		Short Chain Dehydrogenase/Reductase Family 10E, Member 2²
EC 1.2.1.N2¹

External Ids:	HGNC: 25531¹	Entrez Gene: 55711²	Ensembl: ENSG00000064763⁷	UniProtKB: Q96K12³

Export aliases for FAR2 gene to outside databases

Previous GC identifers: GC12P029268 GC12P029376 GC12P029145

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FAR2:

This gene belongs to the short chain dehydrogenase/reductase superfamily. It encodes a reductase enzyme involved in the

first step of wax biosynthesis wherein fatty acids are converted to fatty alcohols. The encoded peroxisomal protein

utilizes saturated fatty acids of 16 or 18 carbons as preferred substrates. Alternatively spliced transcript variants

have been observed for this gene. Related pseudogenes have been identified on chromosomes 2, 14 and 22. (provided by

RefSeq, Nov 2012)

UniProtKB/Swiss-Prot: FACR2_HUMAN, Q96K12

Function: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. The preferred substrates are C16, C18, C18:1 and

C18:2 but low activity can be observed with C10-C14 substrates

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000012.11 NC_018923.1 NT_009714.17

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the FAR2 gene promoter:
Nkx3-1 v4 NF-1 Pax-5 Pbx1a Nkx3-1 v1 POU6F1 (c2) Evi-1 MZF-1 Nkx3-1 v2 Nkx3-1 v3
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): FAR2 promoter sequence

Search SABiosciences Chromatin IP Primers for FAR2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAR2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p11.22 Ensembl cytogenetic band: 12p11.22 HGNC cytogenetic band: 12p11.23

FAR2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAR2 gene location

GeneLoc information about chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12P029302: view genomic region (about GC identifiers)

Start:	29,302,036 bp from pter	End:	29,493,913 bp from pter
Size:	191,878 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: FACR2_HUMAN, Q96K12 (See protein sequence)

Recommended Name: Fatty acyl-CoA reductase 2

Size: 515 amino acids; 59438 Da

Subcellular location: Peroxisome membrane; Multi-pass membrane protein (Potential). Endoplasmic reticulum membrane;

Multi-pass membrane protein (Potential). Note=Peroxisome in cells expressing low levels of the protein. Peroxisome and

endoplasmic reticulum in cells expressing high levels of the protein

Secondary accessions: Q9H0D5 Q9NVW8

Explore the universe of human proteins at neXtProt for FAR2: NX_Q96K12

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q96K12

4 DME Specific Peptides for FAR2 (Q96K12)

FNFDVRQL

SYFRASST

IARSQMARN

TGATGFLGKVL

FAR2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (3 alternative transcripts):

NP_001258712.1 NP_001258713.1 NP_060569.3

ENSEMBL proteins:

ENSP00000450117 ENSP00000443291 ENSP00000182377 ENSP00000449349 ENSP00000449436

ENSP00000449187 ENSP00000447467

Reactome Protein details: Q96K12
Human Recombinant Protein Products:

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	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for FAR2

Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005777	peroxisome	ISS	--
GO:0005778	peroxisomal membrane	IEA	--
GO:0005782	peroxisomal matrix	TAS	--
GO:0005789	endoplasmic reticulum membrane	IEA	--
GO:0016021	integral to membrane	IEA	--

FAR2 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for FAR2

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

FAR2 for domains About GeneDecksing

3 InterPro domains/families:

IPR026055 FAR

IPR016040 NAD(P)-bd_dom

IPR013120 Male_sterile_NAD-bd

Graphical View of Domain Structure for InterPro Entry Q96K12

ProtoNet protein and cluster: Q96K12

1 Blocks protein family: IPB013120 Male sterility C-terminal

UniProtKB/Swiss-Prot: FACR2_HUMAN, Q96K12

Similarity: Belongs to the fatty acyl-CoA reductase family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: FACR2_HUMAN, Q96K12

Function: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. The preferred substrates are C16, C18, C18:1 and

C18:2 but low activity can be observed with C10-C14 substrates

Catalytic activity: Hexadecanal + CoA + NADP(+) = hexadecanoyl-CoA + NADPH

Enzyme Number (IUBMB): EC 1.2.1.n2¹ ²

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FAR2
		2 QIAGEN miScript miRNA Assays for microRNAs that regulate FAR2:
		hsa-miR-3200-5p hsa-miR-202
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Gene Editing
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAR2

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	--	--
GO:0050062	long-chain-fatty-acyl-CoA reductase activity	IEA	--
GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity	IDA	15220348

FAR2 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Metabolism

Metabolism

1.00

Metabolism of lipids and lipoproteins

0.34

Plasmalogen biosynthesis

Plasmalogen biosynthesis

1.00

Peroxisome

Peroxisome

1.00

Peroxisomal lipid metabolism

Peroxisomal lipid metabolism

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

4 Reactome Pathways for FAR2

	Plasmalogen biosynthesis
	Metabolism
	Peroxisomal lipid metabolism
	Metabolism of lipids and lipoproteins

1 Kegg Pathway (Kegg details for FAR2):

Peroxisome

FAR2 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for FAR2

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

2 Interacting proteins for FAR2 (ENSP00000182377⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
AGPS	ENSP00000264167⁴	STRING: ENSP00000264167
GNPAT	ENSP00000355607⁴	STRING: ENSP00000355607

About this table

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008611	ether lipid biosynthetic process	TAS	--
GO:0035336	long-chain fatty-acyl-CoA metabolic process	IDA	15220348
GO:0044255	cellular lipid metabolic process	TAS	--
GO:0044281	small molecule metabolic process	TAS	--

FAR2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for FAR2

10/48 HMDB Compounds for FAR2 (see all 48) About this table

Compound	Synonyms	CAS #	PubMed Ids
(2E)-Decenoyl-CoA	(E)-S-2-decenoate Coenzyme A (see all 15)	10018-95-8	--
(2E)-Dodecenoyl-CoA	2-trans-Dodecenoyl-Coenzyme A (see all 4)	1066-12-2	--
(2E)-Hexadecenoyl-CoA	trans-2-Hexadecenoyl-CoA (see all 4)	4460-95-1	--
(2E)-Octenoyl-CoA	(E)-S-2-octenoate Coenzyme A (see all 16)	10018-94-7	--
(2E)-Tetradecenoyl-CoA	(2E)-Tetradecenoyl-Coenzyme A (see all 8)	38795-33-4	--
1-Butanol	1-Butanol (see all 10)	71-36-3	--
1-Hexadecanol	1-Cetanol (see all 82)	36653-82-4	--
1-Hexanol	1-Hexyl alcohol (see all 30)	111-27-3	--
1-Pentanol	1-Pentol (see all 34)	71-41-0	--
1-Undecanol	1-Hendecanol (see all 25)	112-42-5	--

Search CenterWatch for drugs/clinical trials and news about FAR2 / FACR2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for FAR2 gene (3 alternative transcripts):

NM_001271783.1 NM_001271784.1 NM_018099.4

Unigene Cluster for FAR2:

Fatty acyl CoA reductase 2

Hs.728955 [show with all ESTs]

Unigene Representative Sequence: NM_001271783

10 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000551451 ENST00000536681(uc001ris.4) ENST00000549080 ENST00000547411

ENST00000550541 ENST00000182377(uc001rit.3 uc009zjm.3) ENST00000547116

ENST00000552137 ENST00000551193 ENST00000547759

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		2 QIAGEN miScript miRNA Assays for microRNAs that regulate FAR2:
		hsa-miR-3200-5p hsa-miR-202
		SwitchGear 3'UTR luciferase reporter plasmid: FAR2 3' UTR sequence

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAR2

Additional cDNA sequence:

AK001324.1 AK001927.1 AK027756.1 AK129857.1 AK314670.1 AL136843.1 BC022267.1 BX537693.1

11 DOTS entries:

DT.100744748 DT.208073 DT.121128420 DT.40111229 DT.101981442 DT.40111228 DT.100730511 DT.121128390

DT.415878 DT.95258807 DT.99985406

24/87 AceView cDNA sequences (see all 87):

CR607516 AK027756 BG697652 BG741742 AA489804 BM929835 N67205 BC022267

BQ186333 AA996057 AK129857 BC018460 CK299276 AI057451 NM_018099 AL136843

AI283542 AU136692 AW016785 CB217409 AA479308 BG719367 BG739917 AI279458

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for FAR2 (see all 6) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	^	2	^	3	^	4a	·	4b	^	5	^	6	^	7a	·	7b	^	8	^	9	^	10	^	11	^	12	^	13	^	14	^	15
SP1:
SP2:																	-
SP3:									-		-		-		-
SP4:									-		-		-		-		-
SP5:									-

ECgene alternative splicing isoforms for FAR2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

FAR2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATAAAAATAT

About this image

FAR2 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Brain

Blood Brain Barrier

Postnatal Endothelial Cells

Blood Brain Barrier, Endothelium

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 5 LifeMap Cells

Name

Category

PureStem™ progenitor T42 (Embryonic Progenitor Cell)

PureStem™ progenitor E69 (Embryonic Progenitor Cell)

PureStem™ progenitor T36 (Embryonic Progenitor Cell)

White adipocyte-like cells (Differentiation of ...)

Adipose

Definitive endoderm-like cells (A scalable, suspensi...)

See FAR2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAR2

SOURCE GeneReport for Unigene cluster: Hs.728955

SABiosciences Custom PCR Arrays for FAR2

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAR2

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAR2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for FAR2 gene from 8/21 species (see all 21) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Far2^{1 , 5}	fatty acyl CoA reductase 2^{1, 5}	84.01(n)¹ 87.7(a)¹		6 (78.49 cM)⁵ 330450¹ NM_178797.3¹ NP_848912.1¹ 148047259⁵
chicken (Gallus gallus)	Aves	FAR2¹	fatty acyl CoA reductase 2	67.9(n) 63.62(a)		419043 XM_417235.3 XP_417235.2
lizard (Anolis carolinensis)	Reptilia	-- --	--	62(a) 62(a)	many → 1 many → 1	5(82207004-82248710) 5(82310265-82339770)
zebrafish (Danio rerio)	Actinopterygii	si:dkey-97m3.1⁶	si:dkey-97m3.1	61(a)	1 ↔ 1	4(1849440-1897600)
fruit fly (Drosophila melanogaster)	Insecta	CG5065¹	CG5065	48.3(n) 39.59(a)		36860 NM_001169697.2 NP_001163168.1
worm (Caenorhabditis elegans)	Secernentea	fard-1¹	Protein FARD-1	49.08(n) 37.58(a)		180582 NM_076104.3 NP_508505.1
thale cress (Arabidopsis thaliana)	eudicotyledons	FAR7¹	putative fatty acyl-CoA reductase 7	47.51(n) 36.22(a)		832303 NM_122147.1 NP_197634.1
rice (Oryza sativa)	Liliopsida	Os04g0354400¹	hypothetical protein	48.95(n) 35.14(a)		4335561 NM_001059075.1 NP_001052540.1

ENSEMBL Gene Tree for FAR2 (if available)
TreeFam Gene Tree for FAR2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for FAR2 gene

FAR1²

1 SIMAP similar gene for FAR2 using alignment to 6 protein entries: FACR2_HUMAN (see all proteins):

FAR1

FAR2 for paralogs About GeneDecksing

5/12 Pseudogenes.org Pseudogenes for FAR2 (see all 12)
PGOHUM00000247722 PGOHUM00000247724 PGOHUM00000248002 PGOHUM00000248003 PGOHUM00000246189

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 12 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs11612182^1,2	C,F,H,	--	29202385(+)	`GAAAAA/GAACTT`	2	--	int¹ nc-transcript-variant		11		NS EA NA	688
rs73271545^1,2	C,	--	29202425(+)	`TTCATC/TTATCA`	2	--	int¹ nc-transcript-variant		2		WA	120
rs59442924^1,2	C,	--	29203344(+)	`TCTGGG/TAGGAA`	2	--	int¹ nc-transcript-variant		2		WA	120
rs113410239^1,2	C,	--	29203789(+)	`CAGTGG/ACAACA`	2	--	int¹		2		NA	122
rs78209351^1,2	F,	--	29204007(+)	`GGAAAG/CTTGGT`	2	--	int¹		1		WA	118
rs143167743^1,2	C,	--	29204313(+)	`AATATG/TTATTA`	2	--	int¹		0	--	--	--	--
rs112333349^1,2	C,	--	29204935(+)	`ACTTT-/CTCACA`	2	--	int¹		1		CSA	2
rs60697326^1,2	C,	--	29205276(+)	`ATTAGA/CATTAT`	2	--	int¹		2		WA	120
rs75554254^1,2	F,	--	29205641(+)	`AGGTAA/TATTTC`	2	--	int¹		1		WA	118
rs78977555^1,2		--	29205802(+)	`TGCAAT/CTGATA`	2	--	int¹		1		NA	120

HapMap Linkage Disequilibrium report for FAR2 (29302036 - 29493913 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for FAR2
1 Indel: 11067

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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FAR2 for disorders About GeneDecksing

4 diseases for FAR2: About MalaCards

intestinal volvulus amyloidosis, renal amyloidosis alcoholism

1 disease from the University of Copenhagen DISEASES database for FAR2:

Extrahepatic bile duct carcinoma

Genatlas disease: FAR2

familial amyloidosis,renal,Ostertag type (lysozyme deposit)

Human Genome Epidemiology (HuGE) Navigator: FAR2 (1 document)

Export disorders for FAR2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for FAR2 gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with FAR2)

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world of online information

Mammalian wax biosynthesis: I. Identification of two fatty acyl- coenzyme A reductases with different substrate specificities and tissue distributions. (PubMed id 15220348)^{1, 2, 3} Cheng J.B. and Russell D.W. (2004)
The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. (PubMed id 19027726)^{1, 3} Persson B.... Oppermann U. (2009)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Mammalian wax biosynthesis. II. Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family. (PubMed id 15220349)^{1, 3} Cheng J.B. and Russell D.W. (2004)
Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)^{1, 2} Wiemann S.... Poustka A. (2001)
The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)¹ Aichem A....Groettrup M. (2012)
New gene functions in megakaryopoiesis and platelet fo rmation. (PubMed id 22139419)¹ Gieger C....Soranzo N. (2011)
A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (2011)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 55711	HGNC: 25531	AceView: MLSTD1	Ensembl:ENSG00000064763	euGenes: HUgn55711
ECgene: FAR2	Kegg: 55711	H-InvDB: FAR2

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for FAR2	Pharmacogenomics, SNPs, Pathways

Intellectual Property for FAR2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for FAR2 gene:
Search GeneIP for patents involving FAR2

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

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fatty acyl CoA reductase 2

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fatty acyl CoA reductase 2

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