Aliases for FANCG Gene
External Ids for FANCG Gene
Previous Symbols for FANCG Gene
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G. [provided by RefSeq, Jul 2008]
GeneCards Summary for FANCG Gene
FANCG (Fanconi Anemia, Complementation Group G) is a Protein Coding gene. Diseases associated with FANCG include fanconi anemia, complementation group g and fancg-related fanconi anemia. Among its related pathways are RB in Cancer and Chks in Checkpoint Regulation. GO annotations related to this gene include damaged DNA binding.
UniProtKB/Swiss-Prot for FANCG Gene
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene