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Aliases for FANCD2OS Gene

Aliases for FANCD2OS Gene

  • FANCD2 Opposite Strand 2 3 5
  • Fanconi Anemia Group D2 Protein Opposite Strand Transcript Protein 3 4
  • C3orf24 3 4
  • Chromosome 3 Open Reading Frame 24 2

External Ids for FANCD2OS Gene

Previous HGNC Symbols for FANCD2OS Gene

  • C3orf24

Summaries for FANCD2OS Gene

Entrez Gene Summary for FANCD2OS Gene

  • This gene encodes a conserved protein of unknown function. [provided by RefSeq, Jan 2013]

GeneCards Summary for FANCD2OS Gene

FANCD2OS (FANCD2 Opposite Strand) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FANCD2OS Gene

Genomics for FANCD2OS Gene

Regulatory Elements for FANCD2OS Gene

Enhancers for FANCD2OS Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FANCD2OS on UCSC Golden Path with GeneCards custom track

Genomic Location for FANCD2OS Gene

Chromosome:
3
Start:
10,081,317 bp from pter
End:
10,108,339 bp from pter
Size:
27,023 bases
Orientation:
Minus strand

Genomic View for FANCD2OS Gene

Genes around FANCD2OS on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FANCD2OS Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FANCD2OS Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FANCD2OS Gene

Proteins for FANCD2OS Gene

  • Protein details for FANCD2OS Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96PS1-FACOS_HUMAN
    Recommended name:
    FANCD2 opposite strand protein
    Protein Accession:
    Q96PS1

    Protein attributes for FANCD2OS Gene

    Size:
    177 amino acids
    Molecular mass:
    20188 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FANCD2OS Gene

Proteomics data for FANCD2OS Gene at MOPED

Post-translational modifications for FANCD2OS Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FANCD2OS Gene

No data available for DME Specific Peptides for FANCD2OS Gene

Domains & Families for FANCD2OS Gene

Protein Domains for FANCD2OS Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with FANCD2OS: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for FANCD2OS Gene

Function for FANCD2OS Gene

genes like me logo Genes that share phenotypes with FANCD2OS: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FANCD2OS Gene

Localization for FANCD2OS Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FANCD2OS Gene

Pathways & Interactions for FANCD2OS Gene

SuperPathways for FANCD2OS Gene

No Data Available

Interacting Proteins for FANCD2OS Gene

Gene Ontology (GO) - Biological Process for FANCD2OS Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FANCD2OS Gene

Drugs & Compounds for FANCD2OS Gene

No Compound Related Data Available

Transcripts for FANCD2OS Gene

Unigene Clusters for FANCD2OS Gene

FANCD2 opposite strand:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FANCD2OS Gene

No ASD Table

Relevant External Links for FANCD2OS Gene

GeneLoc Exon Structure for
FANCD2OS
ECgene alternative splicing isoforms for
FANCD2OS

Expression for FANCD2OS Gene

mRNA expression in normal human tissues for FANCD2OS Gene

mRNA differential expression in normal tissues according to GTEx for FANCD2OS Gene

This gene is overexpressed in Testis (x52.6).

SOURCE GeneReport for Unigene cluster for FANCD2OS Gene Hs.190413

genes like me logo Genes that share expression patterns with FANCD2OS: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for FANCD2OS Gene

Orthologs for FANCD2OS Gene

This gene was present in the common ancestor of chordates.

Orthologs for FANCD2OS Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia FANCD2OS 35
  • 90.96 (n)
  • 96.61 (a)
FANCD2OS 36
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FANCD2OS 35
  • 90.02 (n)
  • 96.05 (a)
FANCD2OS 36
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fancd2os 35
  • 87.19 (n)
  • 92.09 (a)
Fancd2os 16
Fancd2os 36
  • 92 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia FANCD2OS 35
  • 99.81 (n)
  • 100 (a)
FANCD2OS 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fancd2os 35
  • 88.14 (n)
  • 93.22 (a)
oppossum
(Monodelphis domestica)
Mammalia FANCD2OS 36
  • 96 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FANCD2OS 36
  • 58 (a)
OneToOne
chicken
(Gallus gallus)
Aves C3ORF24 35
  • 54.83 (n)
  • 50 (a)
FANCD2OS 36
  • 45 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 55 (a)
OneToMany
-- 36
  • 48 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia fancd2os 35
  • 60.69 (n)
  • 53.18 (a)
Species with no ortholog for FANCD2OS:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FANCD2OS Gene

ENSEMBL:
Gene Tree for FANCD2OS (if available)
TreeFam:
Gene Tree for FANCD2OS (if available)

Paralogs for FANCD2OS Gene

(2) SIMAP similar genes for FANCD2OS Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with FANCD2OS: view

No data available for Paralogs for FANCD2OS Gene

Variants for FANCD2OS Gene

Sequence variations from dbSNP and Humsavar for FANCD2OS Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs2619498 -- 10,102,688(+) aatac(A/C)aaaaa intron-variant
rs7618815 -- 10,109,361(+) GGAAG(A/G)AGAGG upstream-variant-2KB
rs10510415 -- 10,104,352(+) GGCTC(C/T)TTCAG reference, synonymous-codon
rs10510416 -- 10,104,403(+) AAGGC(G/T)GACTT reference, synonymous-codon
rs2687883 -- 10,104,540(+) GCGCA(A/T)CTCTG reference, missense

Variation tolerance for FANCD2OS Gene

Residual Variation Intolerance Score: 87.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.66; 56.97% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for FANCD2OS Gene

Disorders for FANCD2OS Gene

Relevant External Links for FANCD2OS

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FANCD2OS

No disorders were found for FANCD2OS Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FANCD2OS Gene

Publications for FANCD2OS Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Overrepresentation of glutamate signaling in Alzheimer's disease: network-based pathway enrichment using meta-analysis of genome-wide association studies. (PMID: 24755620) PAcrez-Palma E. … . (PLoS ONE 2014) 3
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3

Products for FANCD2OS Gene

Sources for FANCD2OS Gene

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