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Aliases for FANCD2OS Gene

Aliases for FANCD2OS Gene

  • FANCD2 Opposite Strand 2 3 5
  • Fanconi Anemia Group D2 Protein Opposite Strand Transcript Protein 3 4
  • C3orf24 3 4
  • Chromosome 3 Open Reading Frame 24 2
  • FANCD2 Opposite Strand Protein 3

External Ids for FANCD2OS Gene

Previous HGNC Symbols for FANCD2OS Gene

  • C3orf24

Summaries for FANCD2OS Gene

Entrez Gene Summary for FANCD2OS Gene

  • This gene encodes a conserved protein of unknown function. [provided by RefSeq, Jan 2013]

GeneCards Summary for FANCD2OS Gene

FANCD2OS (FANCD2 Opposite Strand) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FANCD2OS Gene

Genomics for FANCD2OS Gene

Regulatory Elements for FANCD2OS Gene

Enhancers for FANCD2OS Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around FANCD2OS on UCSC Golden Path with GeneCards custom track

Genomic Location for FANCD2OS Gene

10,081,317 bp from pter
10,108,339 bp from pter
27,023 bases
Minus strand

Genomic View for FANCD2OS Gene

Genes around FANCD2OS on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FANCD2OS Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FANCD2OS Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FANCD2OS Gene

Proteins for FANCD2OS Gene

  • Protein details for FANCD2OS Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    FANCD2 opposite strand protein
    Protein Accession:

    Protein attributes for FANCD2OS Gene

    177 amino acids
    Molecular mass:
    20188 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FANCD2OS Gene

Post-translational modifications for FANCD2OS Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FANCD2OS Gene

No data available for DME Specific Peptides for FANCD2OS Gene

Domains & Families for FANCD2OS Gene

Protein Domains for FANCD2OS Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with FANCD2OS: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for FANCD2OS Gene

Function for FANCD2OS Gene

genes like me logo Genes that share phenotypes with FANCD2OS: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FANCD2OS Gene

Localization for FANCD2OS Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FANCD2OS Gene

Pathways & Interactions for FANCD2OS Gene

SuperPathways for FANCD2OS Gene

No Data Available

Interacting Proteins for FANCD2OS Gene

Gene Ontology (GO) - Biological Process for FANCD2OS Gene


No data available for Pathways by source and SIGNOR curated interactions for FANCD2OS Gene

Drugs & Compounds for FANCD2OS Gene

No Compound Related Data Available

Transcripts for FANCD2OS Gene

Unigene Clusters for FANCD2OS Gene

FANCD2 opposite strand:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FANCD2OS Gene

No ASD Table

Relevant External Links for FANCD2OS Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FANCD2OS Gene

mRNA expression in normal human tissues for FANCD2OS Gene

mRNA differential expression in normal tissues according to GTEx for FANCD2OS Gene

This gene is overexpressed in Testis (x52.6).

NURSA nuclear receptor signaling pathways regulating expression of FANCD2OS Gene:


SOURCE GeneReport for Unigene cluster for FANCD2OS Gene:

genes like me logo Genes that share expression patterns with FANCD2OS: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for FANCD2OS Gene

Orthologs for FANCD2OS Gene

This gene was present in the common ancestor of chordates.

Orthologs for FANCD2OS Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FANCD2OS 34
  • 90.96 (n)
  • 96.61 (a)
  • 96 (a)
(Canis familiaris)
Mammalia FANCD2OS 34
  • 90.02 (n)
  • 96.05 (a)
  • 91 (a)
(Mus musculus)
Mammalia Fancd2os 34
  • 87.19 (n)
  • 92.09 (a)
Fancd2os 16
Fancd2os 35
  • 92 (a)
(Pan troglodytes)
Mammalia FANCD2OS 34
  • 99.81 (n)
  • 100 (a)
  • 100 (a)
(Rattus norvegicus)
Mammalia Fancd2os 34
  • 88.14 (n)
  • 93.22 (a)
(Monodelphis domestica)
Mammalia FANCD2OS 35
  • 96 (a)
(Ornithorhynchus anatinus)
Mammalia FANCD2OS 35
  • 58 (a)
(Gallus gallus)
Aves C3ORF24 34
  • 54.83 (n)
  • 50 (a)
  • 45 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 55 (a)
-- 35
  • 48 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fancd2os 34
  • 60.69 (n)
  • 53.18 (a)
Species where no ortholog for FANCD2OS was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FANCD2OS Gene

Gene Tree for FANCD2OS (if available)
Gene Tree for FANCD2OS (if available)

Paralogs for FANCD2OS Gene

(2) SIMAP similar genes for FANCD2OS Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with FANCD2OS: view

No data available for Paralogs for FANCD2OS Gene

Variants for FANCD2OS Gene

Sequence variations from dbSNP and Humsavar for FANCD2OS Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs2619498 -- 10,102,688(+) aatac(A/C)aaaaa intron-variant
rs7625186 -- 10,103,993(+) ACATG(A/G/T)ACATG intron-variant, downstream-variant-500B, utr-variant-3-prime
rs9839613 -- 10,105,772(+) aaaaa(A/T)tatat intron-variant
rs7628448 -- 10,105,144(+) ACTTC(A/G)CCCAG intron-variant
rs2687883 -- 10,104,540(+) GCGCA(A/T)CTCTG reference, missense

Structural Variations from Database of Genomic Variants (DGV) for FANCD2OS Gene

Variant ID Type Subtype PubMed ID
dgv762e201 CNV deletion 23290073
esv3568607 CNV loss 25503493
esv4117 OTHER complex 18987735
nsv1013567 CNV loss 25217958
nsv1013605 CNV loss 25217958
nsv1073204 CNV deletion 25765185
nsv1121603 CNV deletion 24896259
nsv436362 CNV deletion 17901297
nsv436869 CNV insertion 17901297

Variation tolerance for FANCD2OS Gene

Residual Variation Intolerance Score: 87.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.66; 56.97% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FANCD2OS Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FANCD2OS Gene

Disorders for FANCD2OS Gene

Relevant External Links for FANCD2OS

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FANCD2OS Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FANCD2OS Gene

Publications for FANCD2OS Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 65
  3. Overrepresentation of glutamate signaling in Alzheimer's disease: network-based pathway enrichment using meta-analysis of genome-wide association studies. (PMID: 24755620) PAcrez-Palma E. … . (PLoS ONE 2014) 3 65
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3 65
  5. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 4 65

Products for FANCD2OS Gene

Sources for FANCD2OS Gene

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