Aliases for FANCC Gene
Aliases for FANCC Gene
External Ids for FANCC Gene
- HGNC: 3584
- Entrez Gene: 2176
- Ensembl: ENSG00000158169
- OMIM: 613899
- UniProtKB: Q00597
Previous HGNC Symbols for FANCC Gene
- FACC
Previous GeneCards Identifiers for FANCC Gene
- GC09M088680
- GC09M089589
- GC09M091160
- GC09M093202
- GC09M094940
- GC09M096901
- GC09M097861
- GC09M067470
Summaries for FANCC Gene
-
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C. [provided by RefSeq, Jul 2008]
GeneCards Summary for FANCC Gene
FANCC (Fanconi Anemia Complementation Group C) is a Protein Coding gene. Diseases associated with FANCC include Fanconi Anemia, Complementation Group C and Fanconi Anemia, Complementation Group A. Among its related pathways are Fanconi anemia pathway and Gene Expression.
UniProtKB/Swiss-Prot for FANCC Gene
-
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FANCC Gene
Genomics for FANCC Gene
Regulatory Elements for FANCC Gene
Enhancers for FANCC Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FANCC on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for FANCC Gene
- Chromosome:
- 9
- Start:
- 95,099,054 bp from pter
- End:
- 95,426,796 bp from pter
- Size:
- 327,743 bases
- Orientation:
- Minus strand
Genomic View for FANCC Gene
Genes around FANCC on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9q22.32 by Ensembl
- 9q22.32 by Entrez Gene
- 9q22.32 by HGNC
FANCC Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FANCC Gene
Proteins for FANCC Gene
-
Protein details for FANCC Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q00597-FANCC_HUMAN
- Recommended name:
- Fanconi anemia group C protein
- Protein Accession:
- Q00597
- B1ALR8
Protein attributes for FANCC Gene
- Size:
- 558 amino acids
- Molecular mass:
- 63429 Da
- Quaternary structure:
-
- Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. This complex may also include HSP70. The complex is not found in FA patients. Interacts with ZBTB32. Upon IFNG induction, interacts with STAT1. Interacts with CDK1. Interacts with EIF2AK2; interaction between FA variants and EIF2AK2 may lead to augmented EIF2AK2 activation and cell death.
Protein Expression for FANCC Gene
Post-translational modifications for FANCC Gene
Other Protein References for FANCC Gene
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for FANCC
-
Custom Antibody ServicesOriGene Antibodies for FANCC
- Novus Biologicals Antibodies for FANCC
- Invitrogen Antibodies for FANCC
- antibodies-online Antibodies for FANCC: See all 108
- GeneTex FANCC antibody for FANCC
-
Santa Cruz Biotechnology (SCBT) Antibodies for FANCC
Protein Products
-
OriGene Purified Proteins for FANCC
- Search Origene for MassSpec and Protein Over-expression Lysates for FANCC
- Origene Custom Protein Services for FANCC
- antibodies-online Proteins for FANCC: See all 8
- Search antibodies-online for peptides
- Search GeneTex for Proteins for FANCC
Assay Products
No data available for DME Specific Peptides for FANCC Gene
Domains & Families for FANCC Gene
Gene Families for FANCC Gene
Protein Domains for FANCC Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for FANCC Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for FANCC Gene
Function for FANCC Gene
Molecular function for FANCC Gene
- GENATLAS Biochemistry:
- gene controlling the correct functioning of the replicative,repair and recombination machineries,involved in the fidelity of end-joining of specific double strand break in the cytoplasmic defense against a specific class of genotoxic agents and in the repair of oxidatively damaged DNA
- UniProtKB/Swiss-Prot Function:
- DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 9596688 |
Phenotypes for FANCC Gene
- MGI mutant phenotypes for FANCC:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for FANCC:
-
- Increased vaccinia virus (VACV) infection
- Increased gamma-H2AX phosphorylation
- Decreased hepcidin::fluc mRNA expression
- Synthetic lethal with Ras
- Dynamic nuclei (hole, folded or small irregular)
- Increased G1 DNA content
- G0/1 arrest
- Effect on mitosis
- Increased number of mitotic cells
- Increased viability with MLN4924 (a NAE inhibitor)
- Decreased mitophagy mCherry-Parkin protein expression after carbonyl cyanide m-chlorphenylhydrazone (CCCP) stimulation
- Decreased Sindbis virus (SIN) capsid and autophagosome LC3 protein colocalization
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for FANCC gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FANCC gene
- Search ViGene Biosciences for FANCC
CRISPR Products
-
OriGene CRISPR knockouts for FANCC
-
Santa Cruz Biotechnology (SCBT) CRISPR for FANCC
- GenScript: Design CRISPR guide RNA sequences for FANCC
miRNA for FANCC Gene
- miRTarBase miRNAs that target FANCC
-
- hsa-mir-26b-5p (MIRT029075)
- hsa-mir-15b-5p (MIRT046532)
- hsa-mir-8085 (MIRT531230)
- hsa-mir-6731-5p (MIRT531231)
- hsa-mir-5192 (MIRT531232)
- hsa-mir-6754-5p (MIRT531233)
- hsa-mir-4441 (MIRT531234)
- hsa-mir-4270 (MIRT531235)
- hsa-mir-211-3p (MIRT531236)
- hsa-mir-3613-3p (MIRT531237)
- hsa-mir-6760-5p (MIRT531238)
- hsa-mir-7844-5p (MIRT531239)
- hsa-mir-5007-5p (MIRT531240)
- hsa-mir-548x-3p (MIRT531241)
- hsa-mir-548j-3p (MIRT531242)
- hsa-mir-548aq-3p (MIRT531243)
- hsa-mir-548am-3p (MIRT531244)
- hsa-mir-548aj-3p (MIRT531245)
- hsa-mir-548ah-3p (MIRT531246)
- hsa-mir-548ae-3p (MIRT531247)
- hsa-mir-587 (MIRT648755)
- hsa-mir-302c-5p (MIRT648756)
- hsa-mir-873-5p (MIRT648757)
- hsa-mir-5698 (MIRT706953)
- hsa-mir-744-3p (MIRT706954)
- hsa-mir-6848-3p (MIRT706955)
- hsa-mir-6843-3p (MIRT706956)
- hsa-mir-4423-5p (MIRT706957)
- hsa-mir-6501-5p (MIRT706958)
- hsa-mir-143-5p (MIRT706959)
- hsa-mir-4430 (MIRT706960)
- hsa-mir-3652 (MIRT706961)
- hsa-mir-122-5p (MIRT706962)
- hsa-mir-504-3p (MIRT706963)
- hsa-mir-3135b (MIRT706964)
- hsa-mir-6499-3p (MIRT706965)
- hsa-mir-1273f (MIRT706966)
- hsa-mir-367-5p (MIRT706967)
- hsa-mir-1267 (MIRT706968)
- hsa-mir-6812-3p (MIRT706969)
- hsa-mir-6733-3p (MIRT706970)
miRNA Products
- Search ViGene Biosciences for FANCC
Inhibitory RNA Products
- Origene RNAi, shRNA, and siRNA products in human, mouse, rat for FANCC
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-
ViGene Biosciences ready-to-package AAV shRNAs for FANCC gene
Clone Products
- Sino Biological Human cDNA Clone for FANCC
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Cell Line Products
-
Horizon Cell Lines for FANCC
-
ViGene Biosciences adenoviral particle packaged cDNA for FANCC gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FANCC gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FANCC gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for FANCC Gene
Localization for FANCC Gene
Subcellular locations from UniProtKB/Swiss-Prot for FANCC Gene
- Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| peroxisome | 2 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | TAS,IEA | 9398857 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005737 | cytoplasm | IEA,TAS | 9398857 |
| GO:0005829 | cytosol | IDA | 9596688 |
| GO:0043240 | Fanconi anaemia nuclear complex | IEA,IDA | 20347428 |
Pathways & Interactions for FANCC Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Fanconi anemia pathway | ||
| 2 | BRCA1 Pathway | ||
| 3 | Gene Expression |
.48
|
|
| 4 | p53 Pathway (RnD) | ||
| 5 | Chks in Checkpoint Regulation | ||
Pathways by source for FANCC Gene
1 BioSystems pathway for FANCC Gene
6 Reactome pathways for FANCC Gene
1 KEGG pathway for FANCC Gene
1 GeneGo (Thomson Reuters) pathway for FANCC Gene
1 R&D Systems pathway for FANCC Gene
3 Qiagen pathways for FANCC Gene
Interacting Proteins for FANCC Gene
Selected Interacting proteins:
Q00597-FANCC_HUMAN
ENSP00000289081
for FANCC Gene via
IID
STRING
UniProtKB
MINT
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002262 | myeloid cell homeostasis | IEA | -- |
| GO:0006281 | DNA repair | IEA,TAS | 1574115 |
| GO:0006289 | nucleotide-excision repair | IBA | -- |
| GO:0006461 | protein complex assembly | TAS | 9398857 |
| GO:0006974 | cellular response to DNA damage stimulus | IEA | -- |
Transcripts for FANCC Gene
mRNA/cDNA for FANCC Gene
- (13) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (12) Selected AceView cDNA sequences:
- (12) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FANCC Gene
CRISPR Products
-
OriGene CRISPR knockouts for FANCC
-
Santa Cruz Biotechnology (SCBT) CRISPR for FANCC
- GenScript: Design CRISPR guide RNA sequences for FANCC
miRNA Products
- Search ViGene Biosciences for FANCC
Inhibitory RNA Products
- Origene RNAi, shRNA, and siRNA products in human, mouse, rat for FANCC
- Browse OriGene Inhibitory RNA Products For FANCC
-
ViGene Biosciences ready-to-package AAV shRNAs for FANCC gene
Clone Products
- Sino Biological Human cDNA Clone for FANCC
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Expression for FANCC Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Skeletal Muscle (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for FANCC Gene
This gene is overexpressed in Liver (x5.1).
This gene is overexpressed in Liver (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for FANCC Gene
NURSA nuclear receptor signaling pathways regulating expression of FANCC Gene:
FANCCSOURCE GeneReport for Unigene cluster for FANCC Gene:
Hs.494529mRNA Expression by UniProt/SwissProt for FANCC Gene:
Q00597-FANCC_HUMAN
Tissue specificity:
Ubiquitous.
Evidence on tissue expression from TISSUES for FANCC Gene
- Intestine(4.2)
- Bone marrow(2.1)
Phenotype-based relationships between genes and organs from Gene ORGANizer for FANCC Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- digestive
- endocrine
- immune
- integumentary
- lymphatic
- nervous
- reproductive
- respiratory
- skeletal muscle
- skeleton
- urinary
Organs:
Head and neck:
- brain
- cerebellum
- cranial nerve
- ear
- eye
- eyelid
- face
- head
- neck
- nose
- outer ear
- pituitary gland
- skull
Thorax:
- breast
- esophagus
- heart
- lung
- rib
- rib cage
Abdomen:
- intestine
- kidney
- large intestine
- liver
- stomach
Pelvis:
- anus
- ovary
- pelvis
- penis
- prostate
- rectum
- testicle
- ureter
- uterus
- vagina
- vulva
Limb:
- arm
- digit
- finger
- forearm
- hand
- radius
- upper limb
General:
- blood
- blood vessel
- bone marrow
- coagulation system
- hair
- peripheral nervous system
- red blood cell
- skin
- spinal column
- vertebrae
- white blood cell
Primer Products
-
OriGene qPCR primer pairs for FANCC
-
OriGene qPCR primer pairs and template standards for FANCC
Orthologs for FANCC Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FANCC 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | FANCC 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | FANCC 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Fancc 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Fancc 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | FANCC 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | FANCC 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | FANCC 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | fancc 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | fancc 34 35 |
|
- Species where no ortholog for FANCC was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for FANCC Gene
No data available for Paralogs for FANCC Gene
Variants for FANCC Gene
| SNP ID | Clin | Chr 09 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs104886458 | Pathogenic, Fanconi anemia complementation group C (FANCC) [MIM:227645] | 95,101,723(-) | AGAGC(C/T)GCGAA | intron-variant, reference, missense | |
| rs121917785 | Pathogenic, Fanconi anemia complementation group C (FANCC) [MIM:227645] | 95,107,112(-) | CCTGC(G/T)CTGGG | intron-variant, nc-transcript-variant, downstream-variant-500B, reference, missense | |
| rs1800365 | other, Fanconi anemia complementation group C (FANCC) [MIM:227645] | 95,150,025(-) | GACAG(A/T)TGTTG | intron-variant, reference, missense | |
| rs104886456 | Pathogenic | 95,172,033(-) | ATGTG(A/T)GTATT | intron-variant | |
| rs104886457 | Pathogenic | 95,101,742(-) | TGGCC(C/T)GAGAG | intron-variant, reference, stop-gained |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3621145 | CNV | loss | 21293372 |
| esv3621150 | CNV | loss | 21293372 |
| nsv1038106 | CNV | gain | 25217958 |
| nsv1147999 | OTHER | inversion | 26484159 |
| nsv831656 | CNV | loss | 17160897 |
| nsv831657 | CNV | loss | 17160897 |
| nsv972424 | CNV | duplication | 23825009 |
| nsv972425 | CNV | duplication | 23825009 |
| nsv972787 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
30.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.37;
54.00% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FANCC Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FANCC Gene
Disorders for FANCC Gene
(10) MalaCards diseases for FANCC Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| fanconi anemia, complementation group c |
|
|
| fanconi anemia, complementation group a |
|
|
| fancc-related fanconi anemia |
|
|
| fanconi anemia, complementation group f |
|
|
| fanconi anemia, complementation group b |
|
|
Search FANCC in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
FANCC_HUMAN- Fanconi anemia complementation group C (FANCC) [MIM:227645]: A disorder affecting all bone marrow elements and resulting in anemia, leukopenia and thrombopenia. It is associated with cardiac, renal and limb malformations, dermal pigmentary changes, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage) and defective DNA repair. {ECO:0000269 PubMed:11520787, ECO:0000269 PubMed:15299030, ECO:0000269 PubMed:1574115, ECO:0000269 PubMed:8128956, ECO:0000269 PubMed:8499901, ECO:0000269 PubMed:8844212, ECO:0000269 PubMed:9242535}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Genatlas disease for FANCC Gene
Fanconi anemia,autosomal recessive,complementation group C,characterized by progressive bone marrow failure (pancytopenia),often associated with skeletal abnormalities,radial hypoplasia and vertebral defect and an increased cancer risk with spontaneous chromosomal breakage exacerbated by exposure to DNA cross-linking agents
Relevant External Links for FANCC
Publications for FANCC Gene
- The Fanconi anemia proteins functionally interact with the protein kinase regulated by RNA (PKR). (PMID: 15299030) Zhang X. … Pang Q. (J. Biol. Chem. 2004) 3 4 22 64
- A novel BTB/POZ transcriptional repressor protein interacts with the Fanconi anemia group C protein and PLZF. (PMID: 10572087) Hoatlin M.E. … Licht J.D. (Blood 1999) 3 4 22 64
- Localization of Fanconi anemia C protein to the cytoplasm of mammalian cells. (PMID: 8058745) Youssoufian H. (Proc. Natl. Acad. Sci. U.S.A. 1994) 3 4 22 64
- Regulation of Rev1 by the Fanconi anemia core complex. (PMID: 22266823) Kim H. … D'Andrea A.D. (Nat. Struct. Mol. Biol. 2012) 3 4 64
- Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk. (PMID: 20496165) Monsees G.M. … Han J. (Breast Cancer Res. Treat. 2011) 3 46 64
Products for FANCC Gene
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- Novus Biologicals Antibodies for FANCC
- Novus Biologicals proteins and lysates for FANCC
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- antibodies-online Antibodies for FANCC: See all 108
- Search antibodies-online for kits
- antibodies-online Proteins for FANCC: See all 8
- Search antibodies-online for peptides
- GeneTex FANCC antibody for FANCC
- Search GeneTex for Proteins for FANCC
- ViGene Biosciences adenoviral particle packaged cDNA for FANCC gene
- ViGene Biosciences lentiviral particle packaged cDNA for FANCC gene
- ViGene Biosciences ready-to-package AAV shRNAs for FANCC gene
- Search ViGene Biosciences for FANCC
- Santa Cruz Biotechnology (SCBT) Antibodies for FANCC
- Search Santa Cruz Biotechnology (SCBT) for FANCC siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for FANCC
- Horizon Cell Lines for FANCC
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- VectorBuilder custom plasmid, inducible vectors for FANCC
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FANCC
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FANCC Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
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