FANCC Gene
protein-coding GIFtS: 66
GCID: GC09M097861
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Fanconi anemia, complementation group C
(Previous symbol: FACC)
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Aliases
for FANCC gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Fanconi Anemia, Complementation Group C1 2 | | FAC1 2 3 | | FACC1 2 3 | | FA31 2 | | Fanconi Anemia Group C Protein2 | | Protein FACC3 |
Export aliases for FANCC gene to outside databasesPrevious GC identifers: GC09M088680 GC09M089589 GC09M091160 GC09M093202 GC09M094940 GC09M096901 GC09M067470 |
Summaries
for FANCC gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for FANCC:
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2),FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). Thepreviously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disordercharacterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage,and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity;they are related by their assembly into a common nuclear protein complex. This gene encodes the protein forcomplementation group C. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: FANCC_HUMAN, Q00597Function: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May beimplicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNGinduction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1
Gene Wiki entry for FANCC (Fanconi anemia, complementation group C)
|
Genomic Views
for FANCC gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_008470.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FANCC gene promoter:
STAT1 p53 MEF-2 Nkx2-5 MEF-2A FOXO1a Cart-1 aMEF-2 FOXO1
Other transcription factors
Search SABiosciences Chromatin IP Primers for FANCC
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FANCC |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9q22.3 Ensembl cytogenetic band: 9q22.32 HGNC cytogenetic band: 9q22.3FANCC Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09M097861: view genomic region
(about GC identifiers)
Start:
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97,861,336 bp from pter |
End:
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98,079,991 bp from pter |
Size:
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218,656 bases |
Orientation:
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minus strand |
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Proteins
for FANCC gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: FANCC_HUMAN, Q00597 (See
protein sequence)Recommended Name: Fanconi anemia group C protein Size: 558 amino acids; 63429 Da
Subunit: Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 andFANCM. This complex may also include HSP70. The complex is not found in FA patients. Interacts with ZBTB32. Upon IFNGinduction, interacts with STAT1. Interacts with CDK1. Interacts with EIF2AK2; interaction between FA variants andEIF2AK2 may lead to augmented EIF2AK2 activation and cell death
Subcellular location: Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic
Developmental stage: Expression increases during S phase, is maximal at the G2/M transition, and declines during Mphase (at protein level)
Secondary accessions: B1ALR8Explore the universe of human proteins at neXtProt for FANCC: NX_Q00597
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q00597
FANCC Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_000127.2 NP_001230672.1 NP_001230673.1
ENSEMBL proteins: ENSP00000289081 ENSP00000364454 ENSP00000406908 Reactome Protein details: Q00597
Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
FANCC for ontologies About GeneDecksing
FANCC Antibody Products:
Assay Products for FANCC: |
Protein
Domains /
Families
for FANCC gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FANCC for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q00597ProtoNet protein and cluster: Q00597 1 Blocks protein family: IPB000686 Fanconi anaemia group C protein signature
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Function
for FANCC gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: FANCC_HUMAN, Q00597Function: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May beimplicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNGinduction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1 Genatlas biochemistry entry for FANCC:gene controlling the correct functioning of the replicative,repair and recombination machineries,involved in thefidelity of end-joining of specific double strand break in the cytoplasmic defense against a specific class ofgenotoxic agents and in the repair of oxidatively damaged DNA
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FANCC (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FANCC
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FANCC (NM_000136) | |  | Sino Biological Human cDNA Clone for FANCC | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FANCC | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FANCC |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FANCC |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table
FANCC for ontologies About GeneDecksing
5 GenomeRNAi human phenotypes for FANCC:
Animal Models:
Mouse knock-outs for FANCC: Fancctm1Mab Fancctm1Mgo
7 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Fancc):
FANCC for phenotypes About GeneDecksing
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Pathways & Interactions
for FANCC gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Fanconi Anemia pathway | | | 2 | Immune response_IFN gamma signaling pathway | | | 3 | BRCA1 Pathway | | | 4 | Nucleotide Excision Repair | | | 5 | Chks in Checkpoint Regulation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for FANCC
3 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for FANCC
1  GeneGo (Thomson Reuters) Pathway for FANCC
1  BioSystems Pathway for FANCC
2 
Reactome Pathways for FANCC
FANCC for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for FANCC
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/65 Interacting proteins for FANCC (Q005971, 2, 3 ENSP000002890814) via UniProtKB, MINT, STRING, and/or I2D (see all 65)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| FANCA | O153602, 3, ENSP000003739524 | MINT-19439 MINT-19445 I2D:
score=3 STRING: ENSP00000373952 | | CDK1 | P064932, 3 | MINT-19437 I2D:
score=3 | | FANCE | Q9HB961, 2, 3, ENSP000002297694 | EBI-81625,EBI-396803 MINT-19451 MINT-19450 I2D:
score=4 STRING: ENSP00000229769 | | SPTAN1 | Q138132, 3, ENSP000003618244 | MINT-19443 MINT-7231875 I2D:
score=3 STRING: ENSP00000361824 | | HSPA1A | P081073, ENSP000003648024 | I2D:
score=2 STRING: ENSP00000364802 |
About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table
FANCC for ontologies About GeneDecksing
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Drugs & Compounds
for FANCC gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
FANCC for compounds About GeneDecksing
 Browse Tocris compounds for FANCC
5 Novoseek chemical compound relationships for FANCC gene About this table
Search CenterWatch for drugs/clinical trials and news about FANCC
|
Transcripts
for FANCC gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FANCC gene (3 alternative transcripts): NM_000136.2 NM_001243743.1 NM_001243744.1 Unigene Cluster for FANCC: Fanconi anemia, complementation group C Hs.494529 [show with all ESTs]Unigene Representative Sequence: NM_00013610 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000289081(uc004avh.3 uc004avi.4 uc011lul.1) ENST00000375305(uc010mrm.1 uc022bkl.1)
ENST00000464627 ENST00000480712 ENST00000477942 ENST00000490972 ENST00000464653
ENST00000493098 ENST00000474949 ENST00000433829
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FANCC (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FANCC
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FANCC (NM_000136) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FANCC | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FANCC |
Additional cDNA sequence: AK222871.1 AK304887.1 AK310599.1 AK312548.1 BC015748.1 X66893.1 X66894.1 13 DOTS entries: DT.313375 DT.95162350 DT.100706227 DT.100813029 DT.97769226 DT.40126275 DT.100813030 DT.121205235 DT.121205493 DT.121205515 DT.75169691 DT.91703847 DT.97798713 12 AceView cDNA sequences: BX115735 CA842814 BX509096 H94332 CA848758 BC041030 BC006303 BF311482 AF039185 BF207305 AI591051 H94420
GeneLoc Exon Structure
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Expression
for FANCC gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FANCC expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGGTAAAAC
About this image
See FANCC Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FANCC
SOURCE GeneReport for Unigene cluster: Hs.494529
UniProtKB/Swiss-Prot: FANCC_HUMAN, Q00597Tissue specificity: Ubiquitous
SABiosciences Custom PCR Arrays for FANCC
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FANCC
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FANCC | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FANCC | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FANCC | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FANCC |
Orthologs
for FANCC gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for FANCC gene from 4/10 species (see all 10) About this table
ENSEMBL Gene Tree for FANCC (if available)
TreeFam Gene Tree for FANCC (if available) |
Paralogs
for FANCC gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for FANCC gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FANCC (97861336 - 98079991 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for FANCC
3 CNVs: 83113 96200 83112
Human Gene Mutation Database (HGMD): FANCC
Locus Specific Mutation Databases (LSDB): FANCC
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FANCC |
|
Disorders
/ Diseases
for FANCC gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
FANCC for disorders About GeneDecksing
OMIM gene information: 613899
OMIM disorders: --
UniProtKB/Swiss-Prot: FANCC_HUMAN, Q00597
Defects in FANCC are the cause of Fanconi anemia complementation group C (FANCC) [MIM:227645]. A disorderaffecting all bone marrow elements and resulting in anemia, leukopenia and thrombopenia. It is associated withcardiac, renal and limb malformations, dermal pigmentary changes, and a predisposition to the development ofmalignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomalinstability (increased chromosome breakage) and defective DNA repair
20/35  diseases for FANCC (see all 35): About MalaCardsfanconi's anemia anemia multiple self healing squamous epithelioma fanconi anemia, complementation group m
fanconi anemia, complementation group b xeroderma pigmentosum, group a nevoid basal cell carcinoma syndrome xeroderma pigmentosum
ataxia telangiectasia basal cell carcinoma oral squamous cell carcinoma squamous cell carcinoma
breast cancer susceptibility breast cancer sporadic breast cancer bloom syndrome
epithelial ovarian cancer pancytopenia familial pancreatic cancer familial breast cancer
3 diseases from the University of Copenhagen DISEASES database for FANCC:Bone marrow disease Anemia Genetic disorder 10/16 Novoseek disease relationships for FANCC gene (see all 16) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| fanconis anemia |
97.5 |
51 |
8621788 (3), 12239156 (3), 8058745 (3), 11433346 (2) (see all 31) |
| congenital malformation |
51 |
1 |
8789444 (1) |
| cancer |
45 |
5 |
15277238 (1), 8621788 (1), 12351379 (1), 17909071 (1) (see all 5) |
| anemia |
41.6 |
9 |
7853372 (2), 12670332 (2), 7829076 (1), 16170343 (1) (see all 7) |
| hnscc |
40.2 |
2 |
17409780 (1), 16466850 (1) |
| aplasia |
36.8 |
3 |
10515453 (1), 12351814 (1) |
| pancreatic cancer |
28.8 |
11 |
14726700 (5), 15277238 (1), 15107617 (1), 12750283 (1) (see all 5) |
| ataxia telangiectasia |
26 |
1 |
17277230 (1) |
| chromosomal aberrations |
23 |
1 |
8978774 (1) |
| breast cancer |
22.3 |
4 |
17909071 (1), 14695169 (1), 18990233 (1) |
Genatlas disease: FANCC Fanconi anemia,autosomal recessive,complementation group C,characterized by progressive bone marrow failure(pancytopenia),often associated with skeletal abnormalities,radial hypoplasia and vertebral defect and an increasedcancer risk with spontaneous chromosomal breakage exacerbated by exposure to DNA cross-linking agents
GeneTests: FANCC
Fanconi Anemia
Genetic Association Database (GAD): FANCC
Human Genome Epidemiology (HuGE) Navigator: FANCC (15 documents)
Export disorders for FANCC gene to outside databases
|
Publications
for FANCC gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FANCC gene, integrated from 9 sources (see all 200):
(articles sorted by number of sources associating them with FANCC) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A novel BTB/POZ transcriptional repressor protein interacts with the Fanconi anemia group C protein and PLZF. (PubMed id 10572087)1, 2, 9 Hoatlin M.E.... Licht J.D. (1999)
- Localization of Fanconi anemia C protein to the cytoplasm of mammalian cells. (PubMed id 8058745)1, 2, 9 Youssoufian H. (1994)
- The Fanconi anemia proteins functionally interact with the protein kinase regulated by RNA (PKR). (PubMed id 15299030)1, 2, 9 Zhang X....Pang Q. (2004)
- Regulation of Rev1 by the Fanconi anemia core complex. (PubMed id 22266823)1, 2 Kim H....D'Andrea A.D. (2012)
- A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M. (PubMed id 16116422)1, 2 Meetei A.R....Wang W. (2005)
- Coinheritance of BRCA1 and BRCA2 mutations with Fanconi anemia and Bloom syndrome mutations in Ashkenazi Jewish population: possible role in risk modification for cancer development. (PubMed id 15726604)1, 4 Koren-Michowitz M....Amariglio N. (2005)
- Germ line Fanconi anemia complementation group C mutations and pancreatic cancer. (PubMed id 15695377)1, 4 Couch F.J....Petersen G. (2005)
- X-linked inheritance of Fanconi anemia complementation group B. (PubMed id 15502827)1, 2 Meetei A.R....Joenje H. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome. (PubMed id 12724401)1, 2 Meetei A.R.... Wang W. (2003)
|
External Searches for FANCC gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FANCC gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FANCC gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FANCC gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FANCC | Pharmacogenomics, SNPs, Pathways | | ATLAS Chromosomes in Cancer entry for FANCC | Genetics and Cytogenetics in Oncology and Haematology | | Fanconi Anemia Mutation Database | http://www.rockefeller.edu/fanconi/mutate/jumpc.html | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/FANCC | | NIEHS-SNPs | http://egp.gs.washington.edu/data/fancc/ |
|
| | |
About This Section
| Patent Information for FANCC gene:
Search GeneIP for patents involving FANCC
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FANCC gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | OriGene Antibodies for FANCC | | OriGene shRNA RFP for FANCC | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FANCC | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FANCC | | | OriGene Protein Over-expression Lysate for FANCC | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FANCC | | OriGene 3'-UTR Clone for FANCC | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FANCC | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FANCC | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FANCC | | OriGene Custom Protein Services for FANCC | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FANCC | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FANCC | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FANCC | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FANCC | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FANCC | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FANCC |
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| | | | Search Tocris compounds for FANCC |
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 | | | FANCC Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FANCC |
|  |  |  | | | | ThermoFisher Antibody for FANCC |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FANCC |
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