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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FANCB Gene

protein-coding   GIFtS: 61
GCID: GC0XM014861

Fanconi Anemia, Complementation Group B

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Fanconi Anemia, Complementation Group B1 2     FACB2
FAAP952 3 5     Fanconi Anemia Group B Protein2
Fanconi Anemia-Associated Polypeptide Of 95 KDa2 3     Protein FACB3
FAAP902 5     FLJ340645
FA22     EC 2.8.18
FAB2     EC 3.6.3.148

External Ids:    HGNC: 35831   Entrez Gene: 21872   Ensembl: ENSG000001815447   OMIM: 3005155   UniProtKB: Q8NB913   

Export aliases for FANCB gene to outside databases

Previous GC identifers: GC00U990101 GC0XM014622 GC0XU900615 GC0XM014771 GC0XM012620


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FANCB Gene:
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called
BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called
PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous
recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents,
increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group
do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This
gene encodes the protein for complementation group B. Alternative splicing results in two transcript variants
encoding the same protein. (provided by RefSeq, Jul 2008)

GeneCards Summary for FANCB Gene: 
FANCB (Fanconi anemia, complementation group B) is a protein-coding gene. Diseases associated with FANCB include fanconi anemia, complementation group b, and vater association with macrocephaly and ventriculomegaly, and among its related super-pathways are Nucleotide Excision Repair and Fanconi's Anaemia Pathway.

UniProtKB/Swiss-Prot: FANCB_HUMAN, Q8NB91
Function: DNA repair protein required for FANCD2 ubiquitination

Gene Wiki entry for FANCB Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.2  NT_167197.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FANCB gene promoter:
         AML1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFANCB promoter sequence
   Search SABiosciences Chromatin IP Primers for FANCB

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FANCB


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp22.2   Ensembl cytogenetic band:  Xp22.2   HGNC cytogenetic band: Xp22.2

FANCB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FANCB gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM014861:  view genomic region     (about GC identifiers)

Start:
14,861,529 bp from pter      End:
14,891,191 bp from pter
Size:
29,663 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: FANCB_HUMAN, Q8NB91 (See protein sequence)
Recommended Name: Fanconi anemia group B protein  
Size: 859 amino acids; 97726 Da
Subunit: Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9
and FANCM. The complex is not found in FA patients
Subcellular location: Nucleus
Sequence caution: Sequence=AAH43596.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential
poly-A sequence; Sequence=AAH55411.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential
poly-A sequence;
Secondary accessions: B2RMZ4 Q7Z2U2 Q86XG1

Explore the universe of human proteins at neXtProt for FANCB: NX_Q8NB91

Explore proteomics data for FANCB at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8NB91

  • 2 DME Specific Peptides for FANCB (Q8NB91)
     LETGLKV  NVFEYFL 

    FANCB Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    FANCB Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001018123.1  NP_689846.1  

    ENSEMBL proteins: 
     ENSP00000326819   ENSP00000397849   ENSP00000381378  
    Reactome Protein details: Q8NB91
    Human Recombinant Protein Products for FANCB: 
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    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005654nucleoplasm TAS--
    GO:0043240Fanconi anaemia nuclear complex IDA--

    FANCB for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    FANC: Fanconi anemia, complementation groups

    ProtoNet protein and cluster: Q8NB91


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FANCB_HUMAN, Q8NB91
    Function: DNA repair protein required for FANCD2 ubiquitination

         Enzyme Numbers (IUBMB): EC 2.8.12 EC 3.6.3.142

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI17396147
         
    FANCB for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for FANCB:
     Elongated cells with protrusio 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for FANCB 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for FANCB About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Nucleotide Excision Repair
    DNA Repair0.46
    2Fanconi Anemia pathway
    Fanconi Anemia pathway0.43
    3Meiosis
    Meiosis
    4Fanconi anemia pathway
    Fanconi anemia pathway

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 EMD Millipore Pathway for FANCB
        Meiosis


    2        Reactome Pathways for FANCB
        DNA Repair
    Fanconi Anemia pathway


    1         Kegg Pathway  (Kegg details for FANCB):
        Fanconi anemia pathway


    FANCB for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FANCB

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/39 Interacting proteins for FANCB (Q8NB912, 3 ENSP000003268194) via UniProtKB, MINT, STRING, and/or I2D (see all 39)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FANCAO153602, 3, ENSP000003739524MINT-4789189 MINT-4789226 I2D: score=1 STRING: ENSP00000373952
    FANCGO152872, 3, ENSP000003679104MINT-4789189 MINT-4789226 I2D: score=1 STRING: ENSP00000367910
    C17orf70Q0VG062, 3, ENSP000003332834MINT-4789189 MINT-4789279 MINT-4789226 MINT-4789371 MINT-4789347 I2D: score=2 STRING: ENSP00000333283
    FANCLQ9NW382, 3, ENSP000003850214MINT-4789189 MINT-4789279 MINT-4789226 MINT-4789371 I2D: score=1 STRING: ENSP00000385021
    FANCMQ8IYD82, 3, ENSP000002674304MINT-4789189 MINT-4789279 MINT-4789226 I2D: score=1 STRING: ENSP00000267430
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006281DNA repair TAS--

    FANCB for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FANCB

    Search CenterWatch for drugs/clinical trials and news about FANCB

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FANCB gene (2 alternative transcripts): 
    NM_001018113.1  NM_152633.2  

    Unigene Cluster for FANCB:

    Fanconi anemia, complementation group B
    Hs.554740  [show with all ESTs]
    Unigene Representative Sequence: NM_001018113
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000324138(uc004cwh.1) ENST00000452869 ENST00000489126 ENST00000398334(uc004cwg.1)

    miRNA
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    Additional mRNA sequence: 

    AK091383.1 BC043596.1 BC055411.1 BC136558.1 BC136560.1 HQ234315.1 

    4 DOTS entries:

    DT.75169374  DT.423295  DT.97805281  DT.92060060 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for FANCB    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9
    SP1:                                                                        
    SP2:              -                                                         
    SP3:                                                                        
    SP4:              -     -                                                   
    SP5:                                                                        


    ECgene alternative splicing isoforms for FANCB

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FANCB expression in normal human tissues (normalized intensities)      FANCB embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAAGCAATTT
    FANCB Expression
    About this image


    FANCB expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Testis (Reproductive System)
             XY Germ Cells Testis Cord
     
     Gonad
             XY Germ Cells Testis Cord
     
     Colon (Gastrointestinal Tract)

    See FANCB Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FANCB

    SOURCE GeneReport for Unigene cluster: Hs.554740
        SABiosciences Custom PCR Arrays for FANCB
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for FANCB gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fancb1 , 5 Fanconi anemia, complementation group B1, 5 70.11(n)1
    50.48(a)1
      X (76.75 cM)5
    2372111  NM_001146081.11  NP_001139553.11 
     1649805925 
    chicken
    (Gallus gallus)
    Aves FANCB1 Fanconi anemia, complementation group B 58.18(n)
    43.75(a)
      418628  NM_001199100.1  NP_001186029.1 
    lizard
    (Anolis carolinensis)
    Reptilia FANCB6
    Fanconi anemia, complementation group B
    41(a)
    1 ↔ 1
    3(121143649-121169026)
    zebrafish
    (Danio rerio)
    Actinopterygii fancb1 Fanconi anemia, complementation group B 43.33(n)
    26.67(a)
      692126  NM_001040636.1  NP_001035726.1 


    ENSEMBL Gene Tree for FANCB (if available)
    TreeFam Gene Tree for FANCB (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/408 SNPs in FANCB are shown (see all 408)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0694264
    ----see VAR_0694262 I T mis40--------
    rs59358131,2
    C,H--14775953(+) ACTTGT/GGGATC 2 -- ds50015Minor allele frequency- G:0.00NS EA NA 382
    rs287776931,2
    C--14776108(+) TAAGAT/CGGGAT 2 -- ds50015Minor allele frequency- C:0.12WA NA 8
    rs1859339851,2
    --14776149(+) GCTGGA/TTAATT 2 -- ds50010--------
    rs557252711,2
    --14776216(+) TCCTCG/TATCCA 2 -- ds50010--------
    rs21064121,2
    C,F,A,H--14776227(+) CTAGAC/TGCCCA 2 -- ds500117Minor allele frequency- T:0.49NA EA NS WA CSA 686
    rs1831622591,2
    --14776328(+) GAGGAA/GAGGGA 2 -- ds50010--------
    rs1479734781,2
    --14776414(+) GCCTCA/GGTGTT 2 -- ut310--------
    rs1434342251,2
    C--14776446(+) TAGCAA/CGTAGA 2 -- ut310--------
    rs1876113081,2
    C--14776479(+) AAAACA/GTATTT 2 -- ut310--------

    HapMap Linkage Disequilibrium report for FANCB (14861529 - 14891191 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for FANCB:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv6812CNV Loss18451855
    nsv9934CNV Loss18304495


    Human Gene Mutation Database (HGMD): FANCB

    Locus Specific Mutation Databases (LSDB): FANCB
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 300515   
    OMIM disorders: 300514  
    UniProtKB/Swiss-Prot: FANCB_HUMAN, Q8NB91
  • Fanconi anemia complementation group B (FANCB) [MIM:300514]: A disorder affecting all bone marrow
    elements and resulting in anemia, leukopenia and thrombopenia. It is associated with cardiac, renal and limb
    malformations, dermal pigmentary changes, and a predisposition to the development of malignancies. At the
    cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased
    chromosome breakage) and defective DNA repair. Some severe FANCB cases manifest features of VACTERL syndrome with
    hydrocephalus. Note=The disease is caused by mutations affecting the gene represented in this entry

  • 12 diseases for FANCB:    About MalaCards
    fanconi anemia, complementation group b    vater association with macrocephaly and ventriculomegaly    fancb-related fanconi anemia    vacterl with hydrocephalus, fancb-related
    fanconi's anemia    anemia    breast cancer susceptibility    nijmegen breakage syndrome
    leukopenia    hydrocephalus    breast cancer    squamous cell carcinoma

    1 disease from the University of Copenhagen DISEASES database for FANCB:
    Fanconi's anemia

    FANCB for disorders           About GeneDecksing

    4 Novoseek inferred disease relationships for FANCB gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    fanconis anemia 89 2 16116424 (1), 19861535 (1)
    anemia 34 1 12001267 (1)
    leukemia 28.9 3 16803569 (3)
    cancer 20.3 1 19861535 (1)

    GeneTests: FANCB
    GeneReviews: FANCB
    Genetic Association Database (GAD): FANCB
    Human Genome Epidemiology (HuGE) Navigator: FANCB (621 documents)

    Export disorders for FANCB gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FANCB gene, integrated from 9 sources (see all 37):
    (articles sorted by number of sources associating them with FANCB)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. X-linked inheritance of Fanconi anemia complementation group B. (PubMed id 15502827)1, 2, 3 Meetei A.R....Joenje H. (2004)
    2. The Fanconi anemia family of genes and its correlatio n with breast cancer susceptibility and breast cancer features. (PubMed id 19536649)1, 4 Barroso E....Ribas G. (2009)
    3. Analysis of FANCB and FANCN/PALB2 Fanconi Anemia genes in BRCA1/2-negative Spanish breast cancer families. (PubMed id 18302019)1, 4 Garcia M.J....Benitez J. (2008)
    4. Fanconi anaemia complementation group B presenting as X linked VACTERL with hydrocephalus syndrome. (PubMed id 16679491)1, 2 Holden S.T.... Woods C.G. (2006)
    5. A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M. (PubMed id 16116422)1, 2 Meetei A.R....Wang W. (2005)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Evidence for at least eight Fanconi anemia genes. (PubMed id 9382107)1, 3 Joenje H....Arwert F. (1997)
    9. New advances in the DNA damage response network of Fanconi anemia and BRCA proteins. FAAP95 replaces BRCA2 as the true FANCB protein. (PubMed id 15611632)1, 9 Fei P....Wang W. (2005)
    10. Inactivation of the tumor suppressor genes causing th e hereditary syndromes predisposing to head and neck cancer via promoter hyperm ethylation in sporadic head and neck cancers. (PubMed id 20332657)1, 9 Smith I.M....Califano J.A. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 2187 HGNC: 3583 Ensembl:ENSG00000181544 euGenes: HUgn2187 ECgene: FANCB Kegg: 2187
    H-InvDB: FANCB

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FANCB Pharmacogenomics, SNPs, Pathways
    Fanconi Anemia Mutation Databasehttp://www.rockefeller.edu/fanconi/mutate/jumpb.html
    GeneReviewshttp://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/FANCB

    (Patent information from GeneIP,
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    About This Section
    Patent Information for FANCB gene:
    Search GeneIP for patents involving FANCB

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