FAM9C Gene
protein-coding GIFtS: 40
GCID: GC0XM013053
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family with sequence similarity 9, member C
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Aliases
for FAM9C gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 9, Member C1 2 | | TEX39C1 2 | | Protein FAM9C2 | | Testis Expressed 39C2 |
Export aliases for FAM9C gene to outside databasesPrevious GC identifers: GC0XU990386 GC0XM012415 GC0XM012813 GC0XP011142 GC0XM012964 GC0XM010816 |
Summaries
for FAM9C gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for FAM9C:
This gene is a member of a gene family which arose through duplication on the X chromosome. The encoded protein may belocalized to the nucleus as the protein contains several nuclear localization signals, and has similarity to asynaptonemal complex protein. (provided by RefSeq, Aug 2011)
|
Genomic Views
for FAM9C gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_167197.1
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for FAM9C
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM9C
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM9C |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xp22.2 Ensembl cytogenetic band: Xp22.2 HGNC cytogenetic band: Xp22.32FAM9C Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM013053: view genomic region
(about GC identifiers)
Start:
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13,053,736 bp from pter |
End:
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13,062,917 bp from pter |
Size:
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9,182 bases |
Orientation:
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minus strand |
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Proteins
for FAM9C gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: FAM9C_HUMAN, Q8IZT9 (See
protein sequence)Recommended Name: Protein FAM9C Size: 166 amino acids; 19210 Da
Subcellular location: Nucleus
Secondary accessions: B2R9G7 Q5HYJ6Explore the universe of human proteins at neXtProt for FAM9C: NX_Q8IZT9
FAM9C Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_777561.1
ENSEMBL proteins: ENSP00000369999 ENSP00000334430 ENSP00000409506 ENSP00000439185
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
FAM9C for ontologies About GeneDecksing
FAM9C Antibody Products:
Assay Products for FAM9C: |
Protein
Domains /
Families
for FAM9C gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FAM9C for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8IZT9ProtoNet protein and cluster: Q8IZT9 UniProtKB/Swiss-Prot: FAM9C_HUMAN, Q8IZT9Similarity: Belongs to the FAM9 family |
Function
for FAM9C gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM9C
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM9C
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for FAM9C | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM9C |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM9C |
|
Pathways & Interactions
for FAM9C gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM9C
|
Drugs & Compounds
for FAM9C gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM9C
Search CenterWatch for drugs/clinical trials and news about FAM9C
|
Transcripts
for FAM9C gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM9C gene: NM_174901.5 Unigene Cluster for FAM9C: Family with sequence similarity 9, member C Hs.667546 [show with all ESTs]Unigene Representative Sequence: BX6475805 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000380625 ENST00000468287 ENST00000333995 ENST00000438997 ENST00000542843(uc004cvh.2 uc004cvg.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM9C
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM9C
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FAM9C (NM_174901) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM9C | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM9C |
Additional cDNA sequence: AF494345.1 AK313776.1 BC127957.1 BX647580.1 3 DOTS entries: DT.100009610 DT.101980527 DT.95209370 11 AceView cDNA sequences: BM832944 AI214289 BX648111 BX647580 AI969041 BQ081938 AI650599 BI521529 BX648919 BI522314 AW444496
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for FAM9C About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 |
|---|
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| SP1: | | | - | | | | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for FAM9C
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Expression
for FAM9C gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM9C expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See FAM9C Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM9C
SOURCE GeneReport for Unigene cluster: Hs.667546
UniProtKB/Swiss-Prot: FAM9C_HUMAN, Q8IZT9Tissue specificity: Expressed exclusively in testis
SABiosciences Custom PCR Arrays for FAM9C
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM9C
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat FAM9C | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM9C | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM9C | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM9C |
Orthologs
for FAM9C gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for FAM9C (if available)
TreeFam Gene Tree for FAM9C (if available) |
Paralogs
for FAM9C gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM9C gene
- FAM9A2 FAM9B2
3 SIMAP similar genes for FAM9C using alignment to 3 protein entries: FAM9C_HUMAN (see all proteins):DKFZp686B0429 FAM9A FAM9B
FAM9C for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for FAM9C
PGOHUM00000260945 PGOHUM00000261037
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Genomic Variants
for FAM9C gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM9C (13053736 - 13062917 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FAM9C: --
Locus Specific Mutation Databases (LSDB): FAM9C
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM9C |
|
Disorders
/ Diseases
for FAM9C gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 FAM9C for disorders About MalaCards
FAM9C for disorders About GeneDecksing
OMIM gene information: 300479
OMIM disorders: --
Export disorders for FAM9C gene to outside databases
|
Publications
for FAM9C gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM9C gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM9C) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A new gene family (FAM9) of low-copy repeats in Xp22.3 expressed exclusively in testis: implications for recombinations in this region. (PubMed id 12213195)1, 2, 9 Martinez-Garay I....Kutsche K. (2002)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for FAM9C gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FAM9C gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM9C gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM9C gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM9C | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FAM9C gene:
Search GeneIP for patents involving FAM9C
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM9C gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM9C | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM9C | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM9C | | | OriGene Protein Over-expression Lysate for FAM9C | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM9C | | OriGene 3'-UTR Clone for FAM9C | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM9C | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM9C | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for FAM9C | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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 | | | FAM9C Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM9C |
|  |  |  | | | | Search ThermoFisher Antibodies for FAM9C |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM9C |
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