FAM9B Gene
protein-coding GIFtS: 40
GCID: GC0XM008952
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|
family with sequence similarity 9, member B
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Aliases
for FAM9B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 9, Member B1 2 | | TEX39B1 2 | | Protein FAM9B2 | | Testis Expressed 39B2 |
Export aliases for FAM9B gene to outside databasesPrevious GC identifers: GC0XU990385 GC0XM008802 GC0XM006820 |
Summaries
for FAM9B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for FAM9B:
This gene is a member of a gene family which arose through duplication on the X chromosome. The encoded protein may belocalized to the nucleus as the protein contains several nuclear localization signals, and has similarity to asynaptonemal complex protein. (provided by RefSeq, Aug 2011)
|
Genomic Views
for FAM9B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_167197.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FAM9B gene promoter:
FOXO3a FOXO3 FOXO3b
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM9B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM9B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xp22.32 Ensembl cytogenetic band: Xp22.31 HGNC cytogenetic band: Xp22.31FAM9B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM008952: view genomic region
(about GC identifiers)
Start:
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8,992,273 bp from pter |
End:
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9,132,680 bp from pter |
Size:
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140,408 bases |
Orientation:
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minus strand |
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Proteins
for FAM9B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: FAM9B_HUMAN, Q8IZU0 (See
protein sequence)Recommended Name: Protein FAM9B Size: 186 amino acids; 22438 Da
Subcellular location: Nucleus
Secondary accessions: Q0IJ68Explore the universe of human proteins at neXtProt for FAM9B: NX_Q8IZU0
FAM9B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_995321.1
ENSEMBL proteins: ENSP00000354770 ENSP00000318716 ENSP00000431456 ENSP00000412606
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
FAM9B for ontologies About GeneDecksing
FAM9B Antibody Products:
Assay Products for FAM9B: |
Protein
Domains /
Families
for FAM9B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FAM9B for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8IZU0ProtoNet protein and cluster: Q8IZU0 UniProtKB/Swiss-Prot: FAM9B_HUMAN, Q8IZU0Similarity: Belongs to the FAM9 family |
Function
for FAM9B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM9B
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM9B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FAM9B (NM_205849) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM9B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM9B |
1 GenomeRNAi human phenotype for FAM9B:
|
Pathways & Interactions
for FAM9B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM9B
|
Drugs & Compounds
for FAM9B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM9B
Search CenterWatch for drugs/clinical trials and news about FAM9B
|
Transcripts
for FAM9B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM9B gene (2 alternative transcripts): NM_173696.1 NM_205849.2 Unigene Cluster for FAM9B: Family with sequence similarity 9, member B Hs.733351 [show with all ESTs]Unigene Representative Sequence: AK0975016 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000362066(uc004csh.3) ENST00000327220 ENST00000472522 ENST00000461107
ENST00000494744 ENST00000428477(uc011mhu.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM9B
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM9B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FAM9B (NM_205849) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM9B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM9B |
Additional cDNA sequence: AF494344.1 AK097501.1 BC120955.1 BC120956.1 3 DOTS entries: DT.100700472 DT.99997916 DT.100757581 16 AceView cDNA sequences: CR612309 BX341638 CA429497 CR612898 AK097501 AA431529 AK128470 AA210928 AW663506 NM_205849 AL555604 AF494344 AA301372 BX341637 AA211102 AL578065
GeneLoc Exon Structure
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Expression
for FAM9B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM9B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGGAAAGAGA
About this image
See FAM9B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM9B
SOURCE GeneReport for Unigene cluster: Hs.733351
UniProtKB/Swiss-Prot: FAM9B_HUMAN, Q8IZU0Tissue specificity: Expressed exclusively in testis
SABiosciences Custom PCR Arrays for FAM9B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM9B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat FAM9B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM9B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM9B |
Orthologs
for FAM9B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for FAM9B (if available)
TreeFam Gene Tree for FAM9B (if available) |
Paralogs
for FAM9B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM9B gene
- FAM9A2 FAM9C2
1 SIMAP similar gene for FAM9B using alignment to 3 protein entries: FAM9B_HUMAN (see all proteins):FAM9C
FAM9B for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for FAM9B
PGOHUM00000241181
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Genomic Variants
for FAM9B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for FAM9B (8992273 - 9132680 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for FAM9B
1 CNV: 53046 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM9B |
|
Disorders
/ Diseases
for FAM9B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 FAM9B for disorders About MalaCards
FAM9B for disorders About GeneDecksing
OMIM gene information: 300478
OMIM disorders: --
Export disorders for FAM9B gene to outside databases
|
Publications
for FAM9B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM9B gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM9B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A new gene family (FAM9) of low-copy repeats in Xp22.3 expressed exclusively in testis: implications for recombinations in this region. (PubMed id 12213195)1, 2, 9 Martinez-Garay I....Kutsche K. (2002)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for FAM9B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing FAM9B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM9B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM9B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM9B | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FAM9B gene:
Search GeneIP for patents involving FAM9B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM9B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
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| | |  | OriGene Antibodies for FAM9B | | OriGene shRNA RFP for FAM9B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM9B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM9B | | | OriGene Protein Over-expression Lysate for FAM9B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM9B | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM9B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM9B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for FAM9B | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM9B | | OriGene Custom Protein Services for FAM9B | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM9B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM9B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM9B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM9B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM9B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM9B |
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| | | | Search Tocris compounds for FAM9B |
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 | | | FAM9B Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for FAM9B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM9B |
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