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Aliases for FAM9B Gene

Aliases for FAM9B Gene

  • Family With Sequence Similarity 9, Member B 2 3
  • Testis Expressed 39B 2 3
  • Protein FAM9B 3
  • TEX39B 3

External Ids for FAM9B Gene

Summaries for FAM9B Gene

Entrez Gene Summary for FAM9B Gene

  • This gene is a member of a gene family which arose through duplication on the X chromosome. The encoded protein may be localized to the nucleus as the protein contains several nuclear localization signals, and has similarity to a synaptonemal complex protein. [provided by RefSeq, Aug 2011]

GeneCards Summary for FAM9B Gene

FAM9B (Family With Sequence Similarity 9, Member B) is a Protein Coding gene. An important paralog of this gene is FAM9C.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM9B Gene

Genomics for FAM9B Gene

Genomic Location for FAM9B Gene

9,024,232 bp from pter
9,164,639 bp from pter
140,408 bases
Minus strand

Genomic View for FAM9B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM9B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM9B Gene

Regulatory Elements for FAM9B Gene

Proteins for FAM9B Gene

  • Protein details for FAM9B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM9B
    Protein Accession:
    Secondary Accessions:
    • Q0IJ68
    • Q8N7Z8

    Protein attributes for FAM9B Gene

    186 amino acids
    Molecular mass:
    22438 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM9B Gene


neXtProt entry for FAM9B Gene

Proteomics data for FAM9B Gene at MOPED

Post-translational modifications for FAM9B Gene

No Post-translational modifications

Other Protein References for FAM9B Gene

No data available for DME Specific Peptides for FAM9B Gene

Domains for FAM9B Gene

Protein Domains for FAM9B Gene



  • Belongs to the FAM9 family.:
    • Q8IZU0
genes like me logo Genes that share domains with FAM9B: view

No data available for Gene Families for FAM9B Gene

Function for FAM9B Gene

Gene Ontology (GO) - Molecular Function for FAM9B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with FAM9B: view

Phenotypes for FAM9B Gene

GenomeRNAi human phenotypes for FAM9B:
genes like me logo Genes that share phenotypes with FAM9B: view

miRNA for FAM9B Gene

miRTarBase miRNAs that target FAM9B

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM9B Gene

Localization for FAM9B Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM9B Gene

Subcellular locations from

Jensen Localization Image for FAM9B Gene COMPARTMENTS Subcellular localization image for FAM9B gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for FAM9B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
GO:0005654 nucleoplasm IDA --
genes like me logo Genes that share ontologies with FAM9B: view

Pathways for FAM9B Gene

SuperPathways for FAM9B Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM9B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007286 spermatid development IBA --
genes like me logo Genes that share ontologies with FAM9B: view

No data available for Pathways by source for FAM9B Gene

Transcripts for FAM9B Gene

mRNA/cDNA for FAM9B Gene

Unigene Clusters for FAM9B Gene

Family with sequence similarity 9, member B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM9B Gene

No ASD Table

Relevant External Links for FAM9B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM9B Gene

mRNA expression in normal human tissues for FAM9B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM9B Gene

This gene is overexpressed in Testis (18.9), Uterus (11.7), and Liver (10.5).

SOURCE GeneReport for Unigene cluster for FAM9B Gene Hs.733351

mRNA Expression by UniProt/SwissProt for FAM9B Gene

Tissue specificity: Expressed exclusively in testis.
genes like me logo Genes that share expressions with FAM9B: view

Orthologs for FAM9B Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for FAM9B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FAM9B 36
  • 98.39 (n)
  • 96.24 (a)
FAM9B 37
  • 96 (a)
Species with no ortholog for FAM9B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM9B Gene

Gene Tree for FAM9B (if available)
Gene Tree for FAM9B (if available)

Paralogs for FAM9B Gene

Paralogs for FAM9B Gene

Selected SIMAP similar genes for FAM9B Gene using alignment to 3 proteins: Pseudogenes for FAM9B Gene

genes like me logo Genes that share paralogs with FAM9B: view

Variants for FAM9B Gene

Sequence variations from dbSNP and Humsavar for FAM9B Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs906389 -- 9,033,516(+) CTGTC(A/G)GGCGG intron-variant, upstream-variant-2KB
rs4830617 -- 9,030,129(+) ACTTA(C/G)AGAAC intron-variant, reference, missense
rs5933708 -- 9,032,851(+) AGCCA(C/T)GAAGG intron-variant
rs5934524 -- 9,032,690(+) GTTCA(A/G)ACCCC intron-variant
rs5978287 -- 9,027,146(+) ACAAC(A/G)TGTTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM9B Gene

Variant ID Type Subtype PubMed ID
nsv526672 CNV Gain 19592680
nsv515590 CNV Gain 19592680
nsv6791 CNV Insertion 18451855

Relevant External Links for FAM9B Gene

HapMap Linkage Disequilibrium report

Disorders for FAM9B Gene

Relevant External Links for FAM9B

Genetic Association Database (GAD)
genes like me logo Genes that share disorders with FAM9B: view

No data available for UniProtKB/Swiss-Prot for FAM9B Gene

Publications for FAM9B Gene

  1. A new gene family (FAM9) of low-copy repeats in Xp22.3 expressed exclusively in testis: implications for recombinations in this region. (PMID: 12213195) Martinez-Garay I. … Kutsche K. (Genomics 2002) 2 3 4 23
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Quantitative reactivity profiling predicts functional cysteines in proteomes. (PMID: 21085121) Weerapana E. … Cravatt B.F. (Nature 2010) 2 3
  5. Genetic determinants of serum testosterone concentrations in men. (PMID: 21998597) Ohlsson C. … Haring R. (PLoS Genet. 2011) 2 3

Products for FAM9B Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate FAM9B
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for FAM9B
    • Block miRNA regulation of FAM9B using miScript Target Protectors

    Sources for FAM9B Gene

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